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The map label for this gene is holB [H]

Identifier: 89256881

GI number: 89256881

Start: 1532711

End: 1533622

Strand: Reverse

Name: holB [H]

Synonym: FTL_1604

Alternate gene names: 89256881

Gene position: 1533622-1532711 (Counterclockwise)

Preceding gene: 89256882

Following gene: 89256880

Centisome position: 80.89

GC content: 29.28

Gene sequence:

>912_bases
GTGTTATCTCTAACCACACATCAGCAATTAATAGATAATTTTCTTGAGCAAAAAGCTAAGCAAACGTTGCGTCATGCTTT
TATCTTCAGAGTAGAGGACGCTGTATTACTTGATAGCTTCATCAATTCTTTGTGCCAACTATTGTTAGGGGAGAAAATAC
TTAGTTATGATGACTCGCCTTATATCAATATAGCAGCGATTGAAAATGATGAAATTAAAGTCGCAGAAATAAAAAAAATA
ATCAAAAATTGTGAACTGACTGCACATAATAATTTAGCAAAGATTATTATAATCCAGGGACTCGATTTATTGAACGAATC
AGCGGCTAATGCGTTGCTAAAAACATTAGAAGAACCAACACAAAATACTTTTTTTTTGATGTTTACAAGAAATTATAGTG
ATGTTTTAGCAACTGTCAAAAGTAGATCTTTGGTGTATGATATTAAATTTACTCAAAAAGATAAGTATAATTACCTAAGT
TATACGTTTGATATGTCAAAAGATGCTATTGAAAAGTCATTACAAATGACGCGTAATGATATAAATATAATTGCCAAGAT
TAAACTTGAGCAACATTTTTGGCAACTGCGAAATAACTTAATGAAGGTTTTAGCTAATCAGGTTAATTTAAACGTGTTTC
TCAAAGAAGCTAATCCACATTTTAAGGATACTCTTTATTGGTTAACTAGTATGATTATAGATGTTTATTGTTATAAGCTT
GATGAGCAAAACCAAGGTATCGCAAACTATGATAAACTAGCAATAATAAAATATCTTGCAGCTAAATTTGATGCTGATTG
TATATATAAGTTGTATTCTAAGGCGCTAGAGGCACAAAGTTACTTTGTAAAATTTAAAAATGTAGACAAAGAATTAATCT
TAGAAAACTTAATATTAGAAATTATAAAATAG

Upstream 100 bases:

>100_bases
GTTATAAAAAAAGAAAAAGGATTCTTAAGGTCTAAATTTAGTATGCTTAAAAGAGCAATTACAAACCTCTTGTATGCACG
TAAAATAATATAGGATAAAA

Downstream 100 bases:

>100_bases
GTAAAATAACATGGATGTAAAACAACAACAAAAATTAAAAGCTCAAGCACATAGCTTAAAACCTGTTGTACTAATGGGTG
AGAAAGGCCTAACAGAAAAT

Product: DNA polymerase III, delta prime subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MLSLTTHQQLIDNFLEQKAKQTLRHAFIFRVEDAVLLDSFINSLCQLLLGEKILSYDDSPYINIAAIENDEIKVAEIKKI
IKNCELTAHNNLAKIIIIQGLDLLNESAANALLKTLEEPTQNTFFLMFTRNYSDVLATVKSRSLVYDIKFTQKDKYNYLS
YTFDMSKDAIEKSLQMTRNDINIIAKIKLEQHFWQLRNNLMKVLANQVNLNVFLKEANPHFKDTLYWLTSMIIDVYCYKL
DEQNQGIANYDKLAIIKYLAAKFDADCIYKLYSKALEAQSYFVKFKNVDKELILENLILEIIK

Sequences:

>Translated_303_residues
MLSLTTHQQLIDNFLEQKAKQTLRHAFIFRVEDAVLLDSFINSLCQLLLGEKILSYDDSPYINIAAIENDEIKVAEIKKI
IKNCELTAHNNLAKIIIIQGLDLLNESAANALLKTLEEPTQNTFFLMFTRNYSDVLATVKSRSLVYDIKFTQKDKYNYLS
YTFDMSKDAIEKSLQMTRNDINIIAKIKLEQHFWQLRNNLMKVLANQVNLNVFLKEANPHFKDTLYWLTSMIIDVYCYKL
DEQNQGIANYDKLAIIKYLAAKFDADCIYKLYSKALEAQSYFVKFKNVDKELILENLILEIIK
>Mature_303_residues
MLSLTTHQQLIDNFLEQKAKQTLRHAFIFRVEDAVLLDSFINSLCQLLLGEKILSYDDSPYINIAAIENDEIKVAEIKKI
IKNCELTAHNNLAKIIIIQGLDLLNESAANALLKTLEEPTQNTFFLMFTRNYSDVLATVKSRSLVYDIKFTQKDKYNYLS
YTFDMSKDAIEKSLQMTRNDINIIAKIKLEQHFWQLRNNLMKVLANQVNLNVFLKEANPHFKDTLYWLTSMIIDVYCYKL
DEQNQGIANYDKLAIIKYLAAKFDADCIYKLYSKALEAQSYFVKFKNVDKELILENLILEIIK

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG0470

COG function: function code L; ATPase involved in DNA replication

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008921
- InterPro:   IPR004622
- InterPro:   IPR015199 [H]

Pfam domain/function: PF09115 DNApol3-delta_C [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 35269; Mature: 35269

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLTTHQQLIDNFLEQKAKQTLRHAFIFRVEDAVLLDSFINSLCQLLLGEKILSYDDSP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
YINIAAIENDEIKVAEIKKIIKNCELTAHNNLAKIIIIQGLDLLNESAANALLKTLEEPT
CEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCC
QNTFFLMFTRNYSDVLATVKSRSLVYDIKFTQKDKYNYLSYTFDMSKDAIEKSLQMTRND
CCEEEEEEECCHHHHHHHHHCCCEEEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHCC
INIIAKIKLEQHFWQLRNNLMKVLANQVNLNVFLKEANPHFKDTLYWLTSMIIDVYCYKL
EEEEEEEEHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHEE
DEQNQGIANYDKLAIIKYLAAKFDADCIYKLYSKALEAQSYFVKFKNVDKELILENLILE
CCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
IIK
HHC
>Mature Secondary Structure
MLSLTTHQQLIDNFLEQKAKQTLRHAFIFRVEDAVLLDSFINSLCQLLLGEKILSYDDSP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
YINIAAIENDEIKVAEIKKIIKNCELTAHNNLAKIIIIQGLDLLNESAANALLKTLEEPT
CEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCC
QNTFFLMFTRNYSDVLATVKSRSLVYDIKFTQKDKYNYLSYTFDMSKDAIEKSLQMTRND
CCEEEEEEECCHHHHHHHHHCCCEEEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHCC
INIIAKIKLEQHFWQLRNNLMKVLANQVNLNVFLKEANPHFKDTLYWLTSMIIDVYCYKL
EEEEEEEEHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHEE
DEQNQGIANYDKLAIIKYLAAKFDADCIYKLYSKALEAQSYFVKFKNVDKELILENLILE
CCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
IIK
HHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]