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The map label for this gene is sucC [H]

Identifier: 89256837

GI number: 89256837

Start: 1484657

End: 1485820

Strand: Direct

Name: sucC [H]

Synonym: FTL_1553

Alternate gene names: 89256837

Gene position: 1484657-1485820 (Clockwise)

Preceding gene: 89256835

Following gene: 89256838

Centisome position: 78.3

GC content: 37.8

Gene sequence:

>1164_bases
ATGAACTTACATGAATATCAAGCTAAAGATCTTTTAGAAAGCTATGGTCTAAAAGTTCAAAAAGGTATCGTAGCTCATAA
CCCAAATGAAGCTGCTCAAGCATTTGACCAATTAGGTGGCAAATTTGCTGTGGTTAAAGCTCAGGTACATGCTGGTGGTC
GTGGTAAAGCTGGTGGTGTAAAGGTTGTTAAATCATCTCAAGAAGCTCGTGAAGTAGCAGAAAGCTTAATCGGTAAAAAT
CTTGTTACTTTCCAAACTGATGCTGAAGGTCAGCCAGTTAATTCTGTAGGTATATTTGAAGATGTATACCCTGTTACTCG
TGAGTTATACCTTGGTGCGGTAGTTGATAGATCTAGCCGTAAAGTAACATTCATGGCTTCAACTGAAGGCGGTGTAGATA
TTGAAGAAGTTGCACACAACTCTCCTGAAAAAATCCTTAAAGTAGAAGTAGATCCTTTAGTTGGCTTACAACCTTTCCAA
GCTCGTGAAGTAGCTTTCAAGCTTGGTCTAGAAGGCAAGCAAATCAATGATTTTGTTAAAACTATGCTAGGCGCTTACAA
AGCATTCATCGAATGTGATTTTGCCCTATTTGAAATCAACCCTCTTGCAGTTAGAGAAAACGGAGAGATTGTCTGTGTTG
ATGGTAAAATCAACCTTGATTCAAATGCTCTTTATAGACACCCTAAACTTTTAGCTCTAAGAGACAAATCTCAAGAAAAT
GCTAAAGAACTTAAAGCTTCAGAGCATGAGCTAAACTATGTAGCTCTTGAAGGTAACATCGGTTGTATGGTAAACGGTGC
TGGTCTAGCAATGGCTACTATGGATATTATCCAATTATACGGTGGTAAGCCTGCTAACTTCCTAGATGTAGGTGGTGGTG
CTACTAAAGAGAGAGTAATCGAAGCTTTCAAACTAATCCTAGATGATGAAAATGTAAAAGCTGTTTTAATTAACATCTTC
GGTGGTATTGTTCGTTGTGATATGATCGCTGAAGCAATTATTGAAGCTGTTAAAGAAGTAAATGTAACTGTACCAGTAGT
TGTTCGTCTAGAAGGTAACAATGCAGAAAAAGGTGCTAAAATATTAGCTGATTCAGGTTTAAAACTAATACCTGCTGATG
GTTTAGCTGATGCTGCTGATAAAGTTGTGAAATCACTAGGTTAA

Upstream 100 bases:

>100_bases
AATAAGTATTTTTATTAGAAAAAATAACATAAATGAGTTATTATTTTGTTTGTTATCTAATAAAAATTTTCATCAAACTA
TCAAATAAGGAAGAAAATCA

Downstream 100 bases:

>100_bases
TAAATTAAAACAGTTAAAAGGATATTAAATAATGAGCGTATTAGTTTATAAAAATACAAAAGTTTTAGTACAGGGTTTTA
CTGGTAAAAATGGTACTTTC

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MNLHEYQAKDLLESYGLKVQKGIVAHNPNEAAQAFDQLGGKFAVVKAQVHAGGRGKAGGVKVVKSSQEAREVAESLIGKN
LVTFQTDAEGQPVNSVGIFEDVYPVTRELYLGAVVDRSSRKVTFMASTEGGVDIEEVAHNSPEKILKVEVDPLVGLQPFQ
AREVAFKLGLEGKQINDFVKTMLGAYKAFIECDFALFEINPLAVRENGEIVCVDGKINLDSNALYRHPKLLALRDKSQEN
AKELKASEHELNYVALEGNIGCMVNGAGLAMATMDIIQLYGGKPANFLDVGGGATKERVIEAFKLILDDENVKAVLINIF
GGIVRCDMIAEAIIEAVKEVNVTVPVVVRLEGNNAEKGAKILADSGLKLIPADGLADAADKVVKSLG

Sequences:

>Translated_387_residues
MNLHEYQAKDLLESYGLKVQKGIVAHNPNEAAQAFDQLGGKFAVVKAQVHAGGRGKAGGVKVVKSSQEAREVAESLIGKN
LVTFQTDAEGQPVNSVGIFEDVYPVTRELYLGAVVDRSSRKVTFMASTEGGVDIEEVAHNSPEKILKVEVDPLVGLQPFQ
AREVAFKLGLEGKQINDFVKTMLGAYKAFIECDFALFEINPLAVRENGEIVCVDGKINLDSNALYRHPKLLALRDKSQEN
AKELKASEHELNYVALEGNIGCMVNGAGLAMATMDIIQLYGGKPANFLDVGGGATKERVIEAFKLILDDENVKAVLINIF
GGIVRCDMIAEAIIEAVKEVNVTVPVVVRLEGNNAEKGAKILADSGLKLIPADGLADAADKVVKSLG
>Mature_387_residues
MNLHEYQAKDLLESYGLKVQKGIVAHNPNEAAQAFDQLGGKFAVVKAQVHAGGRGKAGGVKVVKSSQEAREVAESLIGKN
LVTFQTDAEGQPVNSVGIFEDVYPVTRELYLGAVVDRSSRKVTFMASTEGGVDIEEVAHNSPEKILKVEVDPLVGLQPFQ
AREVAFKLGLEGKQINDFVKTMLGAYKAFIECDFALFEINPLAVRENGEIVCVDGKINLDSNALYRHPKLLALRDKSQEN
AKELKASEHELNYVALEGNIGCMVNGAGLAMATMDIIQLYGGKPANFLDVGGGATKERVIEAFKLILDDENVKAVLINIF
GGIVRCDMIAEAIIEAVKEVNVTVPVVVRLEGNNAEKGAKILADSGLKLIPADGLADAADKVVKSLG

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=391, Percent_Identity=47.3145780051151, Blast_Score=356, Evalue=2e-98,
Organism=Homo sapiens, GI157779135, Length=384, Percent_Identity=44.53125, Blast_Score=312, Evalue=4e-85,
Organism=Homo sapiens, GI294862256, Length=364, Percent_Identity=44.7802197802198, Blast_Score=298, Evalue=5e-81,
Organism=Escherichia coli, GI1786948, Length=386, Percent_Identity=62.9533678756477, Blast_Score=474, Evalue=1e-135,
Organism=Caenorhabditis elegans, GI17567829, Length=393, Percent_Identity=45.5470737913486, Blast_Score=330, Evalue=6e-91,
Organism=Caenorhabditis elegans, GI17539378, Length=395, Percent_Identity=44.3037974683544, Blast_Score=322, Evalue=2e-88,
Organism=Saccharomyces cerevisiae, GI6321683, Length=394, Percent_Identity=44.1624365482233, Blast_Score=330, Evalue=3e-91,
Organism=Drosophila melanogaster, GI161078106, Length=390, Percent_Identity=45.8974358974359, Blast_Score=316, Evalue=1e-86,
Organism=Drosophila melanogaster, GI24645208, Length=390, Percent_Identity=45.8974358974359, Blast_Score=316, Evalue=1e-86,
Organism=Drosophila melanogaster, GI281361397, Length=391, Percent_Identity=46.0358056265985, Blast_Score=315, Evalue=4e-86,
Organism=Drosophila melanogaster, GI281361395, Length=391, Percent_Identity=46.0358056265985, Blast_Score=315, Evalue=4e-86,
Organism=Drosophila melanogaster, GI21356231, Length=394, Percent_Identity=42.1319796954315, Blast_Score=293, Evalue=2e-79,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41542; Mature: 41542

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHEYQAKDLLESYGLKVQKGIVAHNPNEAAQAFDQLGGKFAVVKAQVHAGGRGKAGGV
CCCHHHHHHHHHHHCCCEEECCEEECCCCHHHHHHHHCCCEEEEEEEEEECCCCCCCCCE
KVVKSSQEAREVAESLIGKNLVTFQTDAEGQPVNSVGIFEDVYPVTRELYLGAVVDRSSR
EEEECCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCC
KVTFMASTEGGVDIEEVAHNSPEKILKVEVDPLVGLQPFQAREVAFKLGLEGKQINDFVK
EEEEEEECCCCCCHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCHHHHHHH
TMLGAYKAFIECDFALFEINPLAVRENGEIVCVDGKINLDSNALYRHPKLLALRDKSQEN
HHHHHHHHHHEECEEEEEECEEEEECCCCEEEECCEEECCCCCHHCCCEEEEECCCCHHH
AKELKASEHELNYVALEGNIGCMVNGAGLAMATMDIIQLYGGKPANFLDVGGGATKERVI
HHHHHCCCCCCEEEEEECCCEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHH
EAFKLILDDENVKAVLINIFGGIVRCDMIAEAIIEAVKEVNVTVPVVVRLEGNNAEKGAK
HHHHHHHCCCCCCEEHEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHH
ILADSGLKLIPADGLADAADKVVKSLG
EEECCCCEEEECCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNLHEYQAKDLLESYGLKVQKGIVAHNPNEAAQAFDQLGGKFAVVKAQVHAGGRGKAGGV
CCCHHHHHHHHHHHCCCEEECCEEECCCCHHHHHHHHCCCEEEEEEEEEECCCCCCCCCE
KVVKSSQEAREVAESLIGKNLVTFQTDAEGQPVNSVGIFEDVYPVTRELYLGAVVDRSSR
EEEECCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCC
KVTFMASTEGGVDIEEVAHNSPEKILKVEVDPLVGLQPFQAREVAFKLGLEGKQINDFVK
EEEEEEECCCCCCHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCHHHHHHH
TMLGAYKAFIECDFALFEINPLAVRENGEIVCVDGKINLDSNALYRHPKLLALRDKSQEN
HHHHHHHHHHEECEEEEEECEEEEECCCCEEEECCEEECCCCCHHCCCEEEEECCCCHHH
AKELKASEHELNYVALEGNIGCMVNGAGLAMATMDIIQLYGGKPANFLDVGGGATKERVI
HHHHHCCCCCCEEEEEECCCEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHH
EAFKLILDDENVKAVLINIFGGIVRCDMIAEAIIEAVKEVNVTVPVVVRLEGNNAEKGAK
HHHHHHHCCCCCCEEHEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHH
ILADSGLKLIPADGLADAADKVVKSLG
EEECCCCEEEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA