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The map label for this gene is gpmI

Identifier: 89256779

GI number: 89256779

Start: 1417700

End: 1419238

Strand: Direct

Name: gpmI

Synonym: FTL_1490

Alternate gene names: 89256779

Gene position: 1417700-1419238 (Clockwise)

Preceding gene: 89256777

Following gene: 89256780

Centisome position: 74.77

GC content: 34.89

Gene sequence:

>1539_bases
ATGAAAAAAACTACTCTTTTAGTAATCCTAGATGGCTGGGGTTATAGTGATAGTGACTATTTTAACGCTATCAAAAACGC
AAACACTCCAACTTGGGATAGTATTTGGCAAGAATTTCCTAAAACACTTATCAATGCCTCTAGTTTGGAAGTAGGCTTAC
CTAGAAGCCAAATGGGCAACTCTGAGGTTGGTCATGTAAATATAGGCTGTGGTCGAGTGGTCTATCAAGAATTAACAAAA
ATTGATAAAGCTATCGAAGAAAAAACCTTTGGTGATAATAAAGCAATCTGTGCAGCTATTGACAATGTAATCAAAAATGA
CTCTAATCTACACCTAATCGGGTTACTCTCACCAGGTGGTGTTCACTCTCATGAAGAGCATATTTTTGAGATGATAAAAA
TCGCCAAACAAAAAGGTATCAAAAGATTATATTTACATGCATTTTTAGATGGTAGAGATACTCCTCCACGCTCCGCAGAA
AAATCAATTAAAAAAGCAGATAAACTACTACAAGATCTAAACTTAGGCTATATCGCTAGTGTTTGTGGTAGGTATTATGC
AATGGACAGAGATAATCGCTGGGATAGAGTAGAGAAAGCTTATAATGCTATTGTTAACGCTAATGCTGATTTTATCTATG
ACTCAGCACTAGAAGCACTAGAGCAATCGTATGCGCGTGATCAGTCTGATGAGTTTGTTATACCTACTTGTATCAAAAAA
GATGGACATCTTGTAAAAGTCCAAGATAATGATAGTGTTATCTTTATGAACTTTAGAGCAGATAGAGCTAGAGAAATTTC
ACATGCTTTTACTGATGAAAGCTTTGATCATTTCCCAAGAAAAAAACATTTGAATATAAACTTCACTACGCTTACAGAAT
ACGATTCAAAACTTAAATGTGCAGTAGCATTTCCACCTGAGCAGCCTATAAATACTCTTGGCGAAGTATTAATGAAAAAT
CATAAAACTCAACTAAGAATCGCTGAAACTGAAAAATATCCACATGTAACATTCTTTTTTAATGGTGGTAGAGAAGAACA
ATTCGAAGGCGAAGATAGAATACTTATTCCTTCACCAAAGGTAGCTACTTATGATTTACAACCAGAAATGTCAGCTCCAG
AGGTTACAGATAAGTTAGTCGCAGCTATTAATAGTGGTAAATATGATTGTATAGTATGTAACTATGCTAATTCTGATATG
GTTGGTCATACAGGTAATTACGAAGCAGCTATGCAAGCAATTGAGTATCTTGATAAGTGTATTGCCAGATTAAAAGATGC
CATACTTGAGCATGATGGTAACATGTTTATCACGGCAGATCATGGTAATGCTGATATGATGGTTAATCCAGAAACACAAA
AACCTCATACAGCTCACACTACAAATCTTGTGCCATTTATATATGTAGGACATAAAAAAGCTCAAGTTGCTTTAGAGCAT
GGTAAACTCTCAGATATTGCACCAACTCTACTTAATGTCATGGGTATAGCTCAACCTAAAGAAATGACTGGTAAAACTAT
TTTTAACTTTGAAAAATAA

Upstream 100 bases:

>100_bases
AAAATCGTGTATCAAAGCAGACAAACTATAAATATAAAGTTATAATTATGCTTGCGAATCAAAAAATAATTTCAAAAGTT
AAAAGTTTTTGAGGATAATT

Downstream 100 bases:

>100_bases
GGATTTTAGATAAAATGCTTGATGCTAAATATGTTAAGGATAATTTACAACAAGTTGCTGAAAAGCTTGCAACTAGAGGT
TATCAATTTGATATAGCCGA

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-independent PGAM; Phosphoglyceromutase; iPGM

Number of amino acids: Translated: 512; Mature: 512

Protein sequence:

>512_residues
MKKTTLLVILDGWGYSDSDYFNAIKNANTPTWDSIWQEFPKTLINASSLEVGLPRSQMGNSEVGHVNIGCGRVVYQELTK
IDKAIEEKTFGDNKAICAAIDNVIKNDSNLHLIGLLSPGGVHSHEEHIFEMIKIAKQKGIKRLYLHAFLDGRDTPPRSAE
KSIKKADKLLQDLNLGYIASVCGRYYAMDRDNRWDRVEKAYNAIVNANADFIYDSALEALEQSYARDQSDEFVIPTCIKK
DGHLVKVQDNDSVIFMNFRADRAREISHAFTDESFDHFPRKKHLNINFTTLTEYDSKLKCAVAFPPEQPINTLGEVLMKN
HKTQLRIAETEKYPHVTFFFNGGREEQFEGEDRILIPSPKVATYDLQPEMSAPEVTDKLVAAINSGKYDCIVCNYANSDM
VGHTGNYEAAMQAIEYLDKCIARLKDAILEHDGNMFITADHGNADMMVNPETQKPHTAHTTNLVPFIYVGHKKAQVALEH
GKLSDIAPTLLNVMGIAQPKEMTGKTIFNFEK

Sequences:

>Translated_512_residues
MKKTTLLVILDGWGYSDSDYFNAIKNANTPTWDSIWQEFPKTLINASSLEVGLPRSQMGNSEVGHVNIGCGRVVYQELTK
IDKAIEEKTFGDNKAICAAIDNVIKNDSNLHLIGLLSPGGVHSHEEHIFEMIKIAKQKGIKRLYLHAFLDGRDTPPRSAE
KSIKKADKLLQDLNLGYIASVCGRYYAMDRDNRWDRVEKAYNAIVNANADFIYDSALEALEQSYARDQSDEFVIPTCIKK
DGHLVKVQDNDSVIFMNFRADRAREISHAFTDESFDHFPRKKHLNINFTTLTEYDSKLKCAVAFPPEQPINTLGEVLMKN
HKTQLRIAETEKYPHVTFFFNGGREEQFEGEDRILIPSPKVATYDLQPEMSAPEVTDKLVAAINSGKYDCIVCNYANSDM
VGHTGNYEAAMQAIEYLDKCIARLKDAILEHDGNMFITADHGNADMMVNPETQKPHTAHTTNLVPFIYVGHKKAQVALEH
GKLSDIAPTLLNVMGIAQPKEMTGKTIFNFEK
>Mature_512_residues
MKKTTLLVILDGWGYSDSDYFNAIKNANTPTWDSIWQEFPKTLINASSLEVGLPRSQMGNSEVGHVNIGCGRVVYQELTK
IDKAIEEKTFGDNKAICAAIDNVIKNDSNLHLIGLLSPGGVHSHEEHIFEMIKIAKQKGIKRLYLHAFLDGRDTPPRSAE
KSIKKADKLLQDLNLGYIASVCGRYYAMDRDNRWDRVEKAYNAIVNANADFIYDSALEALEQSYARDQSDEFVIPTCIKK
DGHLVKVQDNDSVIFMNFRADRAREISHAFTDESFDHFPRKKHLNINFTTLTEYDSKLKCAVAFPPEQPINTLGEVLMKN
HKTQLRIAETEKYPHVTFFFNGGREEQFEGEDRILIPSPKVATYDLQPEMSAPEVTDKLVAAINSGKYDCIVCNYANSDM
VGHTGNYEAAMQAIEYLDKCIARLKDAILEHDGNMFITADHGNADMMVNPETQKPHTAHTTNLVPFIYVGHKKAQVALEH
GKLSDIAPTLLNVMGIAQPKEMTGKTIFNFEK

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0696

COG function: function code G; Phosphoglyceromutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BPG-independent phosphoglycerate mutase family

Homologues:

Organism=Escherichia coli, GI1790041, Length=511, Percent_Identity=57.9256360078278, Blast_Score=624, Evalue=1e-180,
Organism=Caenorhabditis elegans, GI32564249, Length=511, Percent_Identity=45.2054794520548, Blast_Score=438, Evalue=1e-123,
Organism=Caenorhabditis elegans, GI17507741, Length=511, Percent_Identity=45.2054794520548, Blast_Score=438, Evalue=1e-123,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPMI_FRATO (Q0BKX8)

Other databases:

- EMBL:   CP000437
- RefSeq:   YP_763893.1
- ProteinModelPortal:   Q0BKX8
- STRING:   Q0BKX8
- GeneID:   4307852
- GenomeReviews:   CP000437_GR
- KEGG:   fth:FTH_1444
- eggNOG:   COG0696
- HOGENOM:   HBG613255
- OMA:   DHGNAEL
- ProtClustDB:   PRK05434
- BioCyc:   FTUL393011:FTH_1444-MONOMER
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_01038
- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR011258
- InterPro:   IPR006124
- InterPro:   IPR005995
- Gene3D:   G3DSA:3.40.720.10
- Gene3D:   G3DSA:3.40.1450.10
- PIRSF:   PIRSF001492
- TIGRFAMs:   TIGR01307

Pfam domain/function: PF06415 iPGM_N; PF01676 Metalloenzyme; SSF53649 Alkaline_phosphatase_core; SSF64158 BPG-indep_PGM_N

EC number: =5.4.2.1

Molecular weight: Translated: 57628; Mature: 57628

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: NA

Important sites: ACT_SITE 65-65

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTTLLVILDGWGYSDSDYFNAIKNANTPTWDSIWQEFPKTLINASSLEVGLPRSQMGN
CCCEEEEEEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEECCCHHHCCC
SEVGHVNIGCGRVVYQELTKIDKAIEEKTFGDNKAICAAIDNVIKNDSNLHLIGLLSPGG
CCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCC
VHSHEEHIFEMIKIAKQKGIKRLYLHAFLDGRDTPPRSAEKSIKKADKLLQDLNLGYIAS
CCCHHHHHHHHHHHHHHHCHHEEEHHHEECCCCCCCCHHHHHHHHHHHHHHHCCCHHHHH
VCGRYYAMDRDNRWDRVEKAYNAIVNANADFIYDSALEALEQSYARDQSDEFVIPTCIKK
HHHHHEECCCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCCCCEEEEHEECC
DGHLVKVQDNDSVIFMNFRADRAREISHAFTDESFDHFPRKKHLNINFTTLTEYDSKLKC
CCCEEEEECCCCEEEEEECCCHHHHHHHHHCCCCHHHCCCCEEEEEEEEEEECCCCCEEE
AVAFPPEQPINTLGEVLMKNHKTQLRIAETEKYPHVTFFFNGGREEQFEGEDRILIPSPK
EEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCEEEECCCC
VATYDLQPEMSAPEVTDKLVAAINSGKYDCIVCNYANSDMVGHTGNYEAAMQAIEYLDKC
EEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
IARLKDAILEHDGNMFITADHGNADMMVNPETQKPHTAHTTNLVPFIYVGHKKAQVALEH
HHHHHHHHHHCCCCEEEEEECCCCCEEECCCCCCCCCCCCCCCCEEEEECCCCEEEEECC
GKLSDIAPTLLNVMGIAQPKEMTGKTIFNFEK
CCCHHHHHHHHHHHCCCCCHHHCCCEEEECCC
>Mature Secondary Structure
MKKTTLLVILDGWGYSDSDYFNAIKNANTPTWDSIWQEFPKTLINASSLEVGLPRSQMGN
CCCEEEEEEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEECCCHHHCCC
SEVGHVNIGCGRVVYQELTKIDKAIEEKTFGDNKAICAAIDNVIKNDSNLHLIGLLSPGG
CCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCC
VHSHEEHIFEMIKIAKQKGIKRLYLHAFLDGRDTPPRSAEKSIKKADKLLQDLNLGYIAS
CCCHHHHHHHHHHHHHHHCHHEEEHHHEECCCCCCCCHHHHHHHHHHHHHHHCCCHHHHH
VCGRYYAMDRDNRWDRVEKAYNAIVNANADFIYDSALEALEQSYARDQSDEFVIPTCIKK
HHHHHEECCCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCCCCEEEEHEECC
DGHLVKVQDNDSVIFMNFRADRAREISHAFTDESFDHFPRKKHLNINFTTLTEYDSKLKC
CCCEEEEECCCCEEEEEECCCHHHHHHHHHCCCCHHHCCCCEEEEEEEEEEECCCCCEEE
AVAFPPEQPINTLGEVLMKNHKTQLRIAETEKYPHVTFFFNGGREEQFEGEDRILIPSPK
EEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCEEEECCCC
VATYDLQPEMSAPEVTDKLVAAINSGKYDCIVCNYANSDMVGHTGNYEAAMQAIEYLDKC
EEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
IARLKDAILEHDGNMFITADHGNADMMVNPETQKPHTAHTTNLVPFIYVGHKKAQVALEH
HHHHHHHHHHCCCCEEEEEECCCCCEEECCCCCCCCCCCCCCCCEEEEECCCCEEEEECC
GKLSDIAPTLLNVMGIAQPKEMTGKTIFNFEK
CCCHHHHHHHHHHHCCCCCHHHCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA