| Definition | Francisella tularensis subsp. holarctica LVS chromosome, complete genome. |
|---|---|
| Accession | NC_007880 |
| Length | 1,895,994 |
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The map label for this gene is cadA [H]
Identifier: 89255886
GI number: 89255886
Start: 452890
End: 455031
Strand: Direct
Name: cadA [H]
Synonym: FTL_0476
Alternate gene names: 89255886
Gene position: 452890-455031 (Clockwise)
Preceding gene: 89255885
Following gene: 89255887
Centisome position: 23.89
GC content: 32.91
Gene sequence:
>2142_bases ATGAAAACTGTTGTATTTGTCTATAAAGATACCTTAAAGTCATATAAGGAAAAATTTTTACTAAAAATTGAGAAAGATCT TAAAAATCATCATGAGTATTATACTTTGAAGCTTGATGATTTATCCGAAGTGGTTGAAATTCTTGAGGAGAACTCTAGAA TATGCTGTATTGTTTTAGATAGAGCTAGTTTCAATATTGAAGCTTTTCATAATATTGCGCACCTTAATACAAAGCTGCCA ATATTTGTAGCATCTGACTATAGTCAAAGTATTAAGCTTAATCTGCGTGATTTTAATCTAAATATCAACTTCTTGCAGTA TGATGCTTTAGCTGGTGAGGATTCTGACTTTATTCACAAAACTATCACAAATTATTTTAATTATATATTGCCACCGTTGA CTTATGAGTTATTTAAGTACTCTAAATCTTTTAATTCGGCTTTTTGTACTCCAGGTCACCAAGGAGGTTATGGTTTTCAG CGTTCTGCAGTAGGGGCTTTGTTTTATGATTTTTATGGCGAGAATATTTTTAAGACAGATTTATCTATTTCAATGAAAGA GCTGGGAAGCTTGCTTGATCATTCTGAAGCACATAAGGACGCTGAAGAATATATATCTAAAGTTTTTAAATCAGACAGAT CACTTATTGTTACAAATGGTACTTCAACAGCTAATAAAATAGTGGGAATGTATAGTGTTGTTGATGGTGATACGATTCTT GTAGATAGAAATTGCCATAAATCAGTGACACATCTAATGATGATGGTTGATGTTAACCCAATATATCTAAAACCAACCAG AAATGCTTATGGAATAATTGGTGGGATTCCTAAAAAAGAGTTCAAAAGAGAAACTATCCAAGAAAAGATAGATAATAGTA ATATTGCTGATAAGTGGCCTGAATATGCGGTAGTTACAAACTCAACTTATGACGGTATCCTTTATAATACTGATACGATA CATCGAGAGCTTGATGTTAAAAAACTACATTTTGATAGTGCTTGGATACCATATGCAATATTTCATCCAATTTATAAGCA TAAATCAGCAATGCAAATTGAGCCAAGACCAGAACATATAATTTTTGAAACACAGTCAACACATAAACTTTTAGCGGCCT TTAGCCAATCATCAATGCTGCATATAAAAGGCGACTATAATGAAGAAGTATTAAATGAAGCGTTTATGCTGCATACTTCA ACATCACCTTTTTATCCGATAGTTGCTAGCGTGGAAACAGCAGCAGCAATGATGGAGGGCGAGCAAGGCTATAATCTTAT CGACAAGACTATTAACTTAGCTATAGATTTTAGAAGAGAACTAATCAAACTAAGATCTGAAGCAAATGGTTGGTTTTTTG ATGTTTGGCAACCTGATAATATCTCTAATAAAGAGGCATGGCTTCTGAGAAATGCTGATAAATGGCATGGATTTAAAAAT GTTGATGGTGATTTTCTCTCATTAGACCCTATCAAAATAACAATTCTAACTCCTGGGATAAAAGATAATGATGTTCAAGA TTGGGGAGTACCAGCTGATGTGGTCGCTAAATTCTTAGATGAGCATGATATTGTGGTTGAGAAGTCTGGACCATATTCAT TACTATTTATATTTAGTTTAGGTACAACAAAAGCTAAATCAGTAAGGCTAATTTCGGTATTGAATAAATTCAAACAAATG TATGATGAAAATACACTTGTTGAAAAAATGCTACCAACTTTATATGCGGAAGATCCTAAATTTTATGAAGATATGAGAAT TCAAGAAGTTAGTGAAAGATTACATCAGTATATGAAAGAGGCTAATCTTCCTAATCTCATGTATCATGCTTTTAATGTGC TACCAGAGCAACAGCTAAATCCTCATAGGGCTTTTCAGAAATTATTAAAAGGTAAGGTTAAAAAGGTTCCTCTAGTAGAA CTGTATGAGCATACTTCAGCTGTTATGATATTACCTTATCCACCTGGGATACCTGTTATTTTTCCTGGAGAGAAGATAAC CGAAGAATCTAAAGTAATATTGGATTTCTTATTAATGCTTGAGAAAATAGGTTCGATGTTGCCTGGCTTTGATACAGATA TTCATGGTCCTGAGAGGGCAAAAGATGGTAAGCTCTATATCAAAGTTATTGATGATAAATAA
Upstream 100 bases:
>100_bases CTATATTTTTCTATTATATTATGATAAAAAAATATTTTTAATTTAGATACTTTTAGTATACTGAATTAATACTGTAGTTA TTTTTCTAAGTCGTAAAATT
Downstream 100 bases:
>100_bases TATCTTATTTTTTGAAATAAAATGCTTATAAAACACTAAAAAAAAATGTATAGTGTCATTATCGAGCATAATTTTTTAGG TGGATAGTTCATGCTGAAAA
Product: lysine decarboxylase, inducable
Products: NA
Alternate protein names: LDC [H]
Number of amino acids: Translated: 713; Mature: 713
Protein sequence:
>713_residues MKTVVFVYKDTLKSYKEKFLLKIEKDLKNHHEYYTLKLDDLSEVVEILEENSRICCIVLDRASFNIEAFHNIAHLNTKLP IFVASDYSQSIKLNLRDFNLNINFLQYDALAGEDSDFIHKTITNYFNYILPPLTYELFKYSKSFNSAFCTPGHQGGYGFQ RSAVGALFYDFYGENIFKTDLSISMKELGSLLDHSEAHKDAEEYISKVFKSDRSLIVTNGTSTANKIVGMYSVVDGDTIL VDRNCHKSVTHLMMMVDVNPIYLKPTRNAYGIIGGIPKKEFKRETIQEKIDNSNIADKWPEYAVVTNSTYDGILYNTDTI HRELDVKKLHFDSAWIPYAIFHPIYKHKSAMQIEPRPEHIIFETQSTHKLLAAFSQSSMLHIKGDYNEEVLNEAFMLHTS TSPFYPIVASVETAAAMMEGEQGYNLIDKTINLAIDFRRELIKLRSEANGWFFDVWQPDNISNKEAWLLRNADKWHGFKN VDGDFLSLDPIKITILTPGIKDNDVQDWGVPADVVAKFLDEHDIVVEKSGPYSLLFIFSLGTTKAKSVRLISVLNKFKQM YDENTLVEKMLPTLYAEDPKFYEDMRIQEVSERLHQYMKEANLPNLMYHAFNVLPEQQLNPHRAFQKLLKGKVKKVPLVE LYEHTSAVMILPYPPGIPVIFPGEKITEESKVILDFLLMLEKIGSMLPGFDTDIHGPERAKDGKLYIKVIDDK
Sequences:
>Translated_713_residues MKTVVFVYKDTLKSYKEKFLLKIEKDLKNHHEYYTLKLDDLSEVVEILEENSRICCIVLDRASFNIEAFHNIAHLNTKLP IFVASDYSQSIKLNLRDFNLNINFLQYDALAGEDSDFIHKTITNYFNYILPPLTYELFKYSKSFNSAFCTPGHQGGYGFQ RSAVGALFYDFYGENIFKTDLSISMKELGSLLDHSEAHKDAEEYISKVFKSDRSLIVTNGTSTANKIVGMYSVVDGDTIL VDRNCHKSVTHLMMMVDVNPIYLKPTRNAYGIIGGIPKKEFKRETIQEKIDNSNIADKWPEYAVVTNSTYDGILYNTDTI HRELDVKKLHFDSAWIPYAIFHPIYKHKSAMQIEPRPEHIIFETQSTHKLLAAFSQSSMLHIKGDYNEEVLNEAFMLHTS TSPFYPIVASVETAAAMMEGEQGYNLIDKTINLAIDFRRELIKLRSEANGWFFDVWQPDNISNKEAWLLRNADKWHGFKN VDGDFLSLDPIKITILTPGIKDNDVQDWGVPADVVAKFLDEHDIVVEKSGPYSLLFIFSLGTTKAKSVRLISVLNKFKQM YDENTLVEKMLPTLYAEDPKFYEDMRIQEVSERLHQYMKEANLPNLMYHAFNVLPEQQLNPHRAFQKLLKGKVKKVPLVE LYEHTSAVMILPYPPGIPVIFPGEKITEESKVILDFLLMLEKIGSMLPGFDTDIHGPERAKDGKLYIKVIDDK >Mature_713_residues MKTVVFVYKDTLKSYKEKFLLKIEKDLKNHHEYYTLKLDDLSEVVEILEENSRICCIVLDRASFNIEAFHNIAHLNTKLP IFVASDYSQSIKLNLRDFNLNINFLQYDALAGEDSDFIHKTITNYFNYILPPLTYELFKYSKSFNSAFCTPGHQGGYGFQ RSAVGALFYDFYGENIFKTDLSISMKELGSLLDHSEAHKDAEEYISKVFKSDRSLIVTNGTSTANKIVGMYSVVDGDTIL VDRNCHKSVTHLMMMVDVNPIYLKPTRNAYGIIGGIPKKEFKRETIQEKIDNSNIADKWPEYAVVTNSTYDGILYNTDTI HRELDVKKLHFDSAWIPYAIFHPIYKHKSAMQIEPRPEHIIFETQSTHKLLAAFSQSSMLHIKGDYNEEVLNEAFMLHTS TSPFYPIVASVETAAAMMEGEQGYNLIDKTINLAIDFRRELIKLRSEANGWFFDVWQPDNISNKEAWLLRNADKWHGFKN VDGDFLSLDPIKITILTPGIKDNDVQDWGVPADVVAKFLDEHDIVVEKSGPYSLLFIFSLGTTKAKSVRLISVLNKFKQM YDENTLVEKMLPTLYAEDPKFYEDMRIQEVSERLHQYMKEANLPNLMYHAFNVLPEQQLNPHRAFQKLLKGKVKKVPLVE LYEHTSAVMILPYPPGIPVIFPGEKITEESKVILDFLLMLEKIGSMLPGFDTDIHGPERAKDGKLYIKVIDDK
Specific function: Appears To Play A Role In pH Homeostasis By Consuming Protons And Neutralizing The Acidic By-Products Of Carbohydrate Fermentation. [C]
COG id: COG1982
COG function: function code E; Arginine/lysine/ornithine decarboxylases
Gene ontology:
Cell location: Cytoplasm (Probable) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]
Homologues:
Organism=Escherichia coli, GI1790573, Length=677, Percent_Identity=54.9483013293944, Blast_Score=798, Evalue=0.0, Organism=Escherichia coli, GI1786384, Length=670, Percent_Identity=50.7462686567164, Blast_Score=746, Evalue=0.0, Organism=Escherichia coli, GI221142684, Length=698, Percent_Identity=34.6704871060172, Blast_Score=454, Evalue=1e-128, Organism=Escherichia coli, GI87082193, Length=722, Percent_Identity=31.7174515235457, Blast_Score=329, Evalue=3e-91, Organism=Escherichia coli, GI1786909, Length=609, Percent_Identity=31.1986863711002, Blast_Score=293, Evalue=2e-80,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005308 - InterPro: IPR011193 - InterPro: IPR000310 - InterPro: IPR008286 - InterPro: IPR015424 - InterPro: IPR015421 - InterPro: IPR015422 [H]
Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]
EC number: =4.1.1.18 [H]
Molecular weight: Translated: 81936; Mature: 81936
Theoretical pI: Translated: 6.15; Mature: 6.15
Prosite motif: PS00703 OKR_DC_1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 3.2 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKTVVFVYKDTLKSYKEKFLLKIEKDLKNHHEYYTLKLDDLSEVVEILEENSRICCIVLD CCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHCCCCEEEEEEE RASFNIEAFHNIAHLNTKLPIFVASDYSQSIKLNLRDFNLNINFLQYDALAGEDSDFIHK CCCCCHHHHHHHHHCCCCCEEEEECCCCCEEEEEEEEEEEEEEEEEEECCCCCCCHHHHH TITNYFNYILPPLTYELFKYSKSFNSAFCTPGHQGGYGFQRSAVGALFYDFYGENIFKTD HHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEECC LSISMKELGSLLDHSEAHKDAEEYISKVFKSDRSLIVTNGTSTANKIVGMYSVVDGDTIL CCEEHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEECCCCCHHHHEEEEEEECCCEEE VDRNCHKSVTHLMMMVDVNPIYLKPTRNAYGIIGGIPKKEFKRETIQEKIDNSNIADKWP EECCCHHHHHHEEEEEECCEEEEEECCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCCC EYAVVTNSTYDGILYNTDTIHRELDVKKLHFDSAWIPYAIFHPIYKHKSAMQIEPRPEHI CEEEEECCCCCCEEECCHHHHHHCCCEEEECCCCCCCHHHHHHHHHCCCCEEECCCCCEE IFETQSTHKLLAAFSQSSMLHIKGDYNEEVLNEAFMLHTSTSPFYPIVASVETAAAMMEG EEECCHHHHHHHHHCCCCEEEEECCCCHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHCC EQGYNLIDKTINLAIDFRRELIKLRSEANGWFFDVWQPDNISNKEAWLLRNADKWHGFKN CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEECCHHHCCCCC VDGDFLSLDPIKITILTPGIKDNDVQDWGVPADVVAKFLDEHDIVVEKSGPYSLLFIFSL CCCCEEEECCEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCEEEEEEEEC GTTKAKSVRLISVLNKFKQMYDENTLVEKMLPTLYAEDPKFYEDMRIQEVSERLHQYMKE CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH ANLPNLMYHAFNVLPEQQLNPHRAFQKLLKGKVKKVPLVELYEHTSAVMILPYPPGIPVI CCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEEECCCCCCEE FPGEKITEESKVILDFLLMLEKIGSMLPGFDTDIHGPERAKDGKLYIKVIDDK ECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCC >Mature Secondary Structure MKTVVFVYKDTLKSYKEKFLLKIEKDLKNHHEYYTLKLDDLSEVVEILEENSRICCIVLD CCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHCCCCEEEEEEE RASFNIEAFHNIAHLNTKLPIFVASDYSQSIKLNLRDFNLNINFLQYDALAGEDSDFIHK CCCCCHHHHHHHHHCCCCCEEEEECCCCCEEEEEEEEEEEEEEEEEEECCCCCCCHHHHH TITNYFNYILPPLTYELFKYSKSFNSAFCTPGHQGGYGFQRSAVGALFYDFYGENIFKTD HHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEECC LSISMKELGSLLDHSEAHKDAEEYISKVFKSDRSLIVTNGTSTANKIVGMYSVVDGDTIL CCEEHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEECCCCCHHHHEEEEEEECCCEEE VDRNCHKSVTHLMMMVDVNPIYLKPTRNAYGIIGGIPKKEFKRETIQEKIDNSNIADKWP EECCCHHHHHHEEEEEECCEEEEEECCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCCC EYAVVTNSTYDGILYNTDTIHRELDVKKLHFDSAWIPYAIFHPIYKHKSAMQIEPRPEHI CEEEEECCCCCCEEECCHHHHHHCCCEEEECCCCCCCHHHHHHHHHCCCCEEECCCCCEE IFETQSTHKLLAAFSQSSMLHIKGDYNEEVLNEAFMLHTSTSPFYPIVASVETAAAMMEG EEECCHHHHHHHHHCCCCEEEEECCCCHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHCC EQGYNLIDKTINLAIDFRRELIKLRSEANGWFFDVWQPDNISNKEAWLLRNADKWHGFKN CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEECCHHHCCCCC VDGDFLSLDPIKITILTPGIKDNDVQDWGVPADVVAKFLDEHDIVVEKSGPYSLLFIFSL CCCCEEEECCEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCEEEEEEEEC GTTKAKSVRLISVLNKFKQMYDENTLVEKMLPTLYAEDPKFYEDMRIQEVSERLHQYMKE CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH ANLPNLMYHAFNVLPEQQLNPHRAFQKLLKGKVKKVPLVELYEHTSAVMILPYPPGIPVI CCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEEECCCCCCEE FPGEKITEESKVILDFLLMLEKIGSMLPGFDTDIHGPERAKDGKLYIKVIDDK ECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]