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The map label for this gene is yjcE [H]

Identifier: 89255735

GI number: 89255735

Start: 290059

End: 291357

Strand: Reverse

Name: yjcE [H]

Synonym: FTL_0304

Alternate gene names: 89255735

Gene position: 291357-290059 (Counterclockwise)

Preceding gene: 89255736

Following gene: 89255725

Centisome position: 15.37

GC content: 32.79

Gene sequence:

>1299_bases
ATGAGTGAATATTTTTTATTTAGTTTGCTAACTGTTGTAGCTGCATTAATGAGTTACATTAACACTAAGTTTCTAAAGTT
ACCCAAAGCAATAGGTTTAACAATTCTTTCAATAACCTTTTCGGCACTATGTGCCTCATTTTTGAGTCCATCAAATTTTT
TAGTAGTTGCTTTATCAAGTTTTGATTTCAAAAAAACTGTTCTTGATGGAATGTTATCTTTCTTATTATTTGCTAATGCG
TTGCATTTTAATATGATTGATCTAAAAAAAGAGTTAAAAGCTATATTTGGACTTGCAAGTATTGGTCTATTACTATCAGC
ACTTACAACTGCTATATTAATCTATGGTTTCTGTCTCCTAGTTGGTTTTGAAATTAGTTTAGGCTATTGCTTAGTTTTTG
GAGCGTTGATATCACCTACTGATCCAATTGCAGTAATTAGTACACTTGCTGGTAATAAATCTATACCCAAACATATCAAA
ACACGTGTAGTTGGTGAATCATTGTTTAATGATGCTACAGGAATTGTCCTTTTCGTAGTATTATCAAATATCGTTTTCTT
TAGTAGTGGTGGTGAATTTGGACAAGCTATTAATGGTCATGGTATTGAATATATTTGGATAATAGCTAAACAGATTGGCT
CAGAAGCTGGTGGTGGCATACTACTTGGTTATATATTTGCTAGAGTCGCACTTATATTTCTAAAGACTAATCAAGACTCT
GAAACTTCAATTTTTGTCACATTAGCCGTTGCAAGCATGGGATATGTAATCGCTCATAGCTTAAATGTATCAGGTCCTAT
TGCCATGGTAGTTGCTGGTTTATTCATCGGCAATAATCTTTCAGATCGTAAAAAAACATCTCCAGACCAAGTAGAAAAAC
TGGATAATTTTTGGATGGTTATCGATAATATGCTTAACTCTTTCCTATTTATACTTATAGGTCTAGAATTAACTAGTATA
CCATTTAATCATGGTGCTTTCTGGGTTGGTGCTGCTGGTATATTCATCGTAACATTTGCTAGATTAGTCAGTATATCAAT
ACCAATTACTGTAATAGATAAAAAGCTTACTCGAGCTTCAGCTAAAGATAATTTACTCGTAGCTTGGTCTGGAGTCAGAG
GCGGTATATCTTTAGCATTGGCATTATCATTACCTGATGAAGGTAATGTTATAGTTAGTATTACATATACCGTAGTTATA
TTATCAATACTTGCCCAAGGGTCTACCTTAAAAATTGTTCTAAATATGATTTACCCACATAACATAACTAAGAAAGCGGC
AAATACCGTAGATAACTAA

Upstream 100 bases:

>100_bases
TGATAAGTTAGATGATGGTTTCTTTACACAAAAAGATTTATTAGAAGAATTATCAAAGGCATGCAGCTGGGAGTATAGCT
GTGGCTTATAAGGAATTATT

Downstream 100 bases:

>100_bases
TAAATTATTCGTATTTGTGTTTATAGTAAGCATTACCTAAATATTTGACTAAATAATTGTCTAGTTGTATTGCTTGTGGT
GTTGAGTCTGTAGGTCTACG

Product: Na+/H+ antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MSEYFLFSLLTVVAALMSYINTKFLKLPKAIGLTILSITFSALCASFLSPSNFLVVALSSFDFKKTVLDGMLSFLLFANA
LHFNMIDLKKELKAIFGLASIGLLLSALTTAILIYGFCLLVGFEISLGYCLVFGALISPTDPIAVISTLAGNKSIPKHIK
TRVVGESLFNDATGIVLFVVLSNIVFFSSGGEFGQAINGHGIEYIWIIAKQIGSEAGGGILLGYIFARVALIFLKTNQDS
ETSIFVTLAVASMGYVIAHSLNVSGPIAMVVAGLFIGNNLSDRKKTSPDQVEKLDNFWMVIDNMLNSFLFILIGLELTSI
PFNHGAFWVGAAGIFIVTFARLVSISIPITVIDKKLTRASAKDNLLVAWSGVRGGISLALALSLPDEGNVIVSITYTVVI
LSILAQGSTLKIVLNMIYPHNITKKAANTVDN

Sequences:

>Translated_432_residues
MSEYFLFSLLTVVAALMSYINTKFLKLPKAIGLTILSITFSALCASFLSPSNFLVVALSSFDFKKTVLDGMLSFLLFANA
LHFNMIDLKKELKAIFGLASIGLLLSALTTAILIYGFCLLVGFEISLGYCLVFGALISPTDPIAVISTLAGNKSIPKHIK
TRVVGESLFNDATGIVLFVVLSNIVFFSSGGEFGQAINGHGIEYIWIIAKQIGSEAGGGILLGYIFARVALIFLKTNQDS
ETSIFVTLAVASMGYVIAHSLNVSGPIAMVVAGLFIGNNLSDRKKTSPDQVEKLDNFWMVIDNMLNSFLFILIGLELTSI
PFNHGAFWVGAAGIFIVTFARLVSISIPITVIDKKLTRASAKDNLLVAWSGVRGGISLALALSLPDEGNVIVSITYTVVI
LSILAQGSTLKIVLNMIYPHNITKKAANTVDN
>Mature_431_residues
SEYFLFSLLTVVAALMSYINTKFLKLPKAIGLTILSITFSALCASFLSPSNFLVVALSSFDFKKTVLDGMLSFLLFANAL
HFNMIDLKKELKAIFGLASIGLLLSALTTAILIYGFCLLVGFEISLGYCLVFGALISPTDPIAVISTLAGNKSIPKHIKT
RVVGESLFNDATGIVLFVVLSNIVFFSSGGEFGQAINGHGIEYIWIIAKQIGSEAGGGILLGYIFARVALIFLKTNQDSE
TSIFVTLAVASMGYVIAHSLNVSGPIAMVVAGLFIGNNLSDRKKTSPDQVEKLDNFWMVIDNMLNSFLFILIGLELTSIP
FNHGAFWVGAAGIFIVTFARLVSISIPITVIDKKLTRASAKDNLLVAWSGVRGGISLALALSLPDEGNVIVSITYTVVIL
SILAQGSTLKIVLNMIYPHNITKKAANTVDN

Specific function: Unknown

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Homo sapiens, GI148727259, Length=352, Percent_Identity=23.8636363636364, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI15529998, Length=313, Percent_Identity=25.8785942492013, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1790501, Length=445, Percent_Identity=25.3932584269663, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71980847, Length=355, Percent_Identity=24.2253521126761, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI25150332, Length=323, Percent_Identity=24.7678018575851, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71992107, Length=362, Percent_Identity=22.9281767955801, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71992101, Length=362, Percent_Identity=22.9281767955801, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71990924, Length=356, Percent_Identity=23.314606741573, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71990932, Length=356, Percent_Identity=23.314606741573, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71999819, Length=304, Percent_Identity=22.3684210526316, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71999821, Length=304, Percent_Identity=22.0394736842105, Blast_Score=65, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI71999817, Length=304, Percent_Identity=22.0394736842105, Blast_Score=65, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6320663, Length=417, Percent_Identity=23.9808153477218, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI221473212, Length=349, Percent_Identity=26.647564469914, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI281364513, Length=349, Percent_Identity=26.647564469914, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI221473222, Length=349, Percent_Identity=26.647564469914, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI221473215, Length=349, Percent_Identity=26.647564469914, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI221510740, Length=399, Percent_Identity=23.3082706766917, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR018422
- InterPro:   IPR004705 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 46356; Mature: 46225

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEYFLFSLLTVVAALMSYINTKFLKLPKAIGLTILSITFSALCASFLSPSNFLVVALSS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
FDFKKTVLDGMLSFLLFANALHFNMIDLKKELKAIFGLASIGLLLSALTTAILIYGFCLL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGFEISLGYCLVFGALISPTDPIAVISTLAGNKSIPKHIKTRVVGESLFNDATGIVLFVV
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHH
LSNIVFFSSGGEFGQAINGHGIEYIWIIAKQIGSEAGGGILLGYIFARVALIFLKTNQDS
HHHHHEECCCCCCCCCCCCCCCEEEEEEEHHHCCCCCCCHHHHHHHHHHHEEEEECCCCC
ETSIFVTLAVASMGYVIAHSLNVSGPIAMVVAGLFIGNNLSDRKKTSPDQVEKLDNFWMV
CCEEEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
IDNMLNSFLFILIGLELTSIPFNHGAFWVGAAGIFIVTFARLVSISIPITVIDKKLTRAS
HHHHHHHHHHHHHHHHHEECCCCCCCEEHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHCC
AKDNLLVAWSGVRGGISLALALSLPDEGNVIVSITYTVVILSILAQGSTLKIVLNMIYPH
CCCCEEEEECCCCCCEEEEEEEECCCCCCEEEEHHHHHHHHHHHHCCCHHEEHEEHHCCC
NITKKAANTVDN
CCHHHHHCCCCC
>Mature Secondary Structure 
SEYFLFSLLTVVAALMSYINTKFLKLPKAIGLTILSITFSALCASFLSPSNFLVVALSS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
FDFKKTVLDGMLSFLLFANALHFNMIDLKKELKAIFGLASIGLLLSALTTAILIYGFCLL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGFEISLGYCLVFGALISPTDPIAVISTLAGNKSIPKHIKTRVVGESLFNDATGIVLFVV
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHH
LSNIVFFSSGGEFGQAINGHGIEYIWIIAKQIGSEAGGGILLGYIFARVALIFLKTNQDS
HHHHHEECCCCCCCCCCCCCCCEEEEEEEHHHCCCCCCCHHHHHHHHHHHEEEEECCCCC
ETSIFVTLAVASMGYVIAHSLNVSGPIAMVVAGLFIGNNLSDRKKTSPDQVEKLDNFWMV
CCEEEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
IDNMLNSFLFILIGLELTSIPFNHGAFWVGAAGIFIVTFARLVSISIPITVIDKKLTRAS
HHHHHHHHHHHHHHHHHEECCCCCCCEEHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHCC
AKDNLLVAWSGVRGGISLALALSLPDEGNVIVSITYTVVILSILAQGSTLKIVLNMIYPH
CCCCEEEEECCCCCCEEEEEEEECCCCCCEEEEHHHHHHHHHHHHCCCHHEEHEEHHCCC
NITKKAANTVDN
CCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]