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The map label for this gene is frr [H]

Identifier: 89255661

GI number: 89255661

Start: 227593

End: 228150

Strand: Direct

Name: frr [H]

Synonym: FTL_0227

Alternate gene names: 89255661

Gene position: 227593-228150 (Clockwise)

Preceding gene: 89255660

Following gene: 89255662

Centisome position: 12.0

GC content: 34.59

Gene sequence:

>558_bases
ATGATAAATGATATTCTAAAAGATGCTGAGAATAGAATGAAAAAATCATTAGAGGTTTTAGCTGATGATTTGGCAAAAAT
TAGAACTGGTAGAGCACATCCTGATCTATTAGCACATGTTACAATAGATTATTATGGTGTTGAGACGCCAATAACTCAAG
CAGCTAATATTACTGTGCTTGATGCTAGAACTTTGGGGATTACTCCTTGGGAAAAAGGTTTATCGAGCAAGATTGAAAAA
GCTATATTGACTTCTGATCTTGGGCTTAATCCTACTAACTTGGGTGATTCATTAAGAGTCCCTATGCCTGCTTTGAATGA
GGAGAGAAGAAAAGAATTAGTTAAACTAGTTAAATCTGAAACTGAAGCGGGTAGGGTATCTATTAGAAATATTCGTCGTG
ATGCTAATGGTGATATCAAAGAACTTCTAAAAGAAAAAGAAATTACTGAGGATCAAGCTAAAAAAGCTGAAGATGATATT
CAGAAGATTACTGATAAAATGATTGCTCAGGCTGATGCTCTTGCAGCTAAAAAAGAACAAGATCTAATGGCTGTGTAA

Upstream 100 bases:

>100_bases
TAACTCAGCCTAACGCTTTAGTTGATGCTGTTTTGGACTCAAAGTATGGTACTTGGGTTACTTTAGACTAATTAATTTTT
TTTAAAAAGGATTATTTTTT

Downstream 100 bases:

>100_bases
TTGCTTAGATTTCCCAATAATAACTTGTATTTTTGTTTATTCTTTCTTATCATTTAGCTAACTTAATTTTTTTCATAATA
TTTATGACATCGGCTAAAGA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MINDILKDAENRMKKSLEVLADDLAKIRTGRAHPDLLAHVTIDYYGVETPITQAANITVLDARTLGITPWEKGLSSKIEK
AILTSDLGLNPTNLGDSLRVPMPALNEERRKELVKLVKSETEAGRVSIRNIRRDANGDIKELLKEKEITEDQAKKAEDDI
QKITDKMIAQADALAAKKEQDLMAV

Sequences:

>Translated_185_residues
MINDILKDAENRMKKSLEVLADDLAKIRTGRAHPDLLAHVTIDYYGVETPITQAANITVLDARTLGITPWEKGLSSKIEK
AILTSDLGLNPTNLGDSLRVPMPALNEERRKELVKLVKSETEAGRVSIRNIRRDANGDIKELLKEKEITEDQAKKAEDDI
QKITDKMIAQADALAAKKEQDLMAV
>Mature_185_residues
MINDILKDAENRMKKSLEVLADDLAKIRTGRAHPDLLAHVTIDYYGVETPITQAANITVLDARTLGITPWEKGLSSKIEK
AILTSDLGLNPTNLGDSLRVPMPALNEERRKELVKLVKSETEAGRVSIRNIRRDANGDIKELLKEKEITEDQAKKAEDDI
QKITDKMIAQADALAAKKEQDLMAV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Escherichia coli, GI1786368, Length=183, Percent_Identity=51.9125683060109, Blast_Score=199, Evalue=6e-53,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20553; Mature: 20553

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINDILKDAENRMKKSLEVLADDLAKIRTGRAHPDLLAHVTIDYYGVETPITQAANITVL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHEEEHHHCCCCCCCCCCCCEEEE
DARTLGITPWEKGLSSKIEKAILTSDLGLNPTNLGDSLRVPMPALNEERRKELVKLVKSE
ECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
TEAGRVSIRNIRRDANGDIKELLKEKEITEDQAKKAEDDIQKITDKMIAQADALAAKKEQ
CHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLMAV
HCCCC
>Mature Secondary Structure
MINDILKDAENRMKKSLEVLADDLAKIRTGRAHPDLLAHVTIDYYGVETPITQAANITVL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHEEEHHHCCCCCCCCCCCCEEEE
DARTLGITPWEKGLSSKIEKAILTSDLGLNPTNLGDSLRVPMPALNEERRKELVKLVKSE
ECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
TEAGRVSIRNIRRDANGDIKELLKEKEITEDQAKKAEDDIQKITDKMIAQADALAAKKEQ
CHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLMAV
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA