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The map label for this gene is pyrH [H]

Identifier: 89255660

GI number: 89255660

Start: 226814

End: 227563

Strand: Direct

Name: pyrH [H]

Synonym: FTL_0226

Alternate gene names: 89255660

Gene position: 226814-227563 (Clockwise)

Preceding gene: 89255659

Following gene: 89255661

Centisome position: 11.96

GC content: 36.67

Gene sequence:

>750_bases
ATGTCTAATGATTCGTCAGAATGTTCTCAAAAACTCCCTAAACTTAAGAGAATTCTTCTTAAGTTAAGTGGAGAATCTTT
ATCTGCAGATCAGGGTTTTGGTATAAATGTTGAATCTGCTCAACCTATCATAAATCAGATTAAAACTCTTACTAATTTTG
GTGTTGAGCTTGCTTTAGTGGTTGGCGGTGGTAATATTTTGCGTGGTGGTAGAGCTAATTTTGGTAACAAAATTAGAAGA
GCTACTGCTGACTCAATGGGGATGATTGCTACTATGATTAATGCTTTAGCTCTTCGTGATATGCTTATTAGTGAAGGTGT
TGATGCTGAGGTTTTTTCAGCAAAAGGAGTGGATGGGTTGTTGAAAGTTGCTAGTGCGCATGAATTTAATCAAGAACTTG
CCAAGGGTAGGGTTTTGATATTTGCAGGTGGTACTGGTAACCCATTTGTAACAACTGATACTACTGCTAGTTTAAGAGCT
GTTGAAATTGGTGCTGATGCTTTGTTAAAGGCTACGACAGTTAATGGCGTGTATGATAAAGACCCAAACAAATATTCAGA
TGCTAAGCGTTTTGATAAAGTCACATTTTCAGAAGTGGTTAGTAAAGAACTTAATGTGATGGATTTGGGAGCATTTACTC
AGTGTAGAGATTTCAGTATTCCGATATATGTATTTGATTTAACTCAGCCTAACGCTTTAGTTGATGCTGTTTTGGACTCA
AAGTATGGTACTTGGGTTACTTTAGACTAA

Upstream 100 bases:

>100_bases
TAAAGTAGTTAATTTCATCAGATTAGATGTTGGTGAAGGTATCGAGAAGAAAGAAGAAGACTTCGCAGCAGAGGTGATGA
GTCAAATTAAAGGTTAATAT

Downstream 100 bases:

>100_bases
TTAATTTTTTTTAAAAAGGATTATTTTTTATGATAAATGATATTCTAAAAGATGCTGAGAATAGAATGAAAAAATCATTA
GAGGTTTTAGCTGATGATTT

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MSNDSSECSQKLPKLKRILLKLSGESLSADQGFGINVESAQPIINQIKTLTNFGVELALVVGGGNILRGGRANFGNKIRR
ATADSMGMIATMINALALRDMLISEGVDAEVFSAKGVDGLLKVASAHEFNQELAKGRVLIFAGGTGNPFVTTDTTASLRA
VEIGADALLKATTVNGVYDKDPNKYSDAKRFDKVTFSEVVSKELNVMDLGAFTQCRDFSIPIYVFDLTQPNALVDAVLDS
KYGTWVTLD

Sequences:

>Translated_249_residues
MSNDSSECSQKLPKLKRILLKLSGESLSADQGFGINVESAQPIINQIKTLTNFGVELALVVGGGNILRGGRANFGNKIRR
ATADSMGMIATMINALALRDMLISEGVDAEVFSAKGVDGLLKVASAHEFNQELAKGRVLIFAGGTGNPFVTTDTTASLRA
VEIGADALLKATTVNGVYDKDPNKYSDAKRFDKVTFSEVVSKELNVMDLGAFTQCRDFSIPIYVFDLTQPNALVDAVLDS
KYGTWVTLD
>Mature_248_residues
SNDSSECSQKLPKLKRILLKLSGESLSADQGFGINVESAQPIINQIKTLTNFGVELALVVGGGNILRGGRANFGNKIRRA
TADSMGMIATMINALALRDMLISEGVDAEVFSAKGVDGLLKVASAHEFNQELAKGRVLIFAGGTGNPFVTTDTTASLRAV
EIGADALLKATTVNGVYDKDPNKYSDAKRFDKVTFSEVVSKELNVMDLGAFTQCRDFSIPIYVFDLTQPNALVDAVLDSK
YGTWVTLD

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=236, Percent_Identity=46.1864406779661, Blast_Score=203, Evalue=9e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 26690; Mature: 26559

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNDSSECSQKLPKLKRILLKLSGESLSADQGFGINVESAQPIINQIKTLTNFGVELALV
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEE
VGGGNILRGGRANFGNKIRRATADSMGMIATMINALALRDMLISEGVDAEVFSAKGVDGL
EECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHH
LKVASAHEFNQELAKGRVLIFAGGTGNPFVTTDTTASLRAVEIGADALLKATTVNGVYDK
HHHHHHHHHHHHHHCCEEEEEECCCCCCEEEECCCCCEEEEEECCHHHEEEEEECCCCCC
DPNKYSDAKRFDKVTFSEVVSKELNVMDLGAFTQCRDFSIPIYVFDLTQPNALVDAVLDS
CCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCEEEEECCCCHHHHHHHHCC
KYGTWVTLD
CCCCEEEEC
>Mature Secondary Structure 
SNDSSECSQKLPKLKRILLKLSGESLSADQGFGINVESAQPIINQIKTLTNFGVELALV
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEE
VGGGNILRGGRANFGNKIRRATADSMGMIATMINALALRDMLISEGVDAEVFSAKGVDGL
EECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHH
LKVASAHEFNQELAKGRVLIFAGGTGNPFVTTDTTASLRAVEIGADALLKATTVNGVYDK
HHHHHHHHHHHHHHCCEEEEEECCCCCCEEEECCCCCEEEEEECCHHHEEEEEECCCCCC
DPNKYSDAKRFDKVTFSEVVSKELNVMDLGAFTQCRDFSIPIYVFDLTQPNALVDAVLDS
CCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCEEEEECCCCHHHHHHHHCC
KYGTWVTLD
CCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA