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The map label for this gene is pdxY [H]

Identifier: 89255632

GI number: 89255632

Start: 199206

End: 200057

Strand: Reverse

Name: pdxY [H]

Synonym: FTL_0198

Alternate gene names: 89255632

Gene position: 200057-199206 (Counterclockwise)

Preceding gene: 89255633

Following gene: 89255631

Centisome position: 10.55

GC content: 34.51

Gene sequence:

>852_bases
ATGTCTTTAAAAATCCCTAAAGTATTATCTATCCAATCTCATGTCGCCTATGGCTATGCCGGTAATAAAGCAGCAGTTTT
CCCAATGCAGAAACTAGGCATAGAAGTTTCGCCAATATACACAGTACAGCTATCAAACCATACTCAGTATGATTTTTATA
AAGGATCTTTCTTTAGTGCTGAAGATATCCAAAATGTTATCGATGGTATGATAGCAAATGGTTTTTTAGCACAACAAAAT
GCCATCTTATCTGGATATATTGGTAACTTAGAGATTGCCAAGGTTATTGCAAATACTGTTATAGAGCTTAAAAAGTTAAA
CAGCGATAGTTTATATTGCTGTGACCCTGTCTTTGGTGACAAGCATGATGAAGATGAAAACGGCCATATTTTTGCATCTG
CTGATCACCCTAATATTTTTTTAAGCCACTTATTGCCTTTAGCCGATATTATCACGCCTAATCTATTCGAGCTTAGTGTT
TTAAGTGGTTCTCAAATATGTAATTATGATGATATCATTACAGCTTGTAAAAAGCTTATTAGCAAAACAGGAAATCATAA
CCAAATAATAATCGTAACCAGCGTATCATTTAGTAAAGATAAAACTGGTATAGCCATATACCACCATGGTAACTTCTCAT
ATCTTGAATCTCCTAAATACAAGGTTCAACCTAAGGTTAGCGGCTCCGGCGATATTACAGCAGCAATGTTTTTAAGTTAT
CTGTTAAAAGGTAAAAACTTAGATGAAACTCTCAAAGCAGTAACACAGTGCTTAGATGGTATCTTTAGGACAACTCATCA
ATTAAACACGGATGAGCTAGCATTAATTCAAGCACAGGAGTATATTAGATAA

Upstream 100 bases:

>100_bases
CACTATTAACTTATTTATCAAAATAGGCAAACTTGGTGATAAGCAAGCATCTGTTGACCTACTTGCAAACATCCAAACTA
ACTTAGGTATATAATTATCA

Downstream 100 bases:

>100_bases
TGGATCGCTATAGTAAAATTACAAATGTGCATATGTACAAGAGAGAAATTGTACTGCTTAAAAGTCGTCCGTGTGCTTAC
GGCAAATGTACATTTTGTGA

Product: pyridoxal kinase

Products: NA

Alternate protein names: PM kinase [H]

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MSLKIPKVLSIQSHVAYGYAGNKAAVFPMQKLGIEVSPIYTVQLSNHTQYDFYKGSFFSAEDIQNVIDGMIANGFLAQQN
AILSGYIGNLEIAKVIANTVIELKKLNSDSLYCCDPVFGDKHDEDENGHIFASADHPNIFLSHLLPLADIITPNLFELSV
LSGSQICNYDDIITACKKLISKTGNHNQIIIVTSVSFSKDKTGIAIYHHGNFSYLESPKYKVQPKVSGSGDITAAMFLSY
LLKGKNLDETLKAVTQCLDGIFRTTHQLNTDELALIQAQEYIR

Sequences:

>Translated_283_residues
MSLKIPKVLSIQSHVAYGYAGNKAAVFPMQKLGIEVSPIYTVQLSNHTQYDFYKGSFFSAEDIQNVIDGMIANGFLAQQN
AILSGYIGNLEIAKVIANTVIELKKLNSDSLYCCDPVFGDKHDEDENGHIFASADHPNIFLSHLLPLADIITPNLFELSV
LSGSQICNYDDIITACKKLISKTGNHNQIIIVTSVSFSKDKTGIAIYHHGNFSYLESPKYKVQPKVSGSGDITAAMFLSY
LLKGKNLDETLKAVTQCLDGIFRTTHQLNTDELALIQAQEYIR
>Mature_282_residues
SLKIPKVLSIQSHVAYGYAGNKAAVFPMQKLGIEVSPIYTVQLSNHTQYDFYKGSFFSAEDIQNVIDGMIANGFLAQQNA
ILSGYIGNLEIAKVIANTVIELKKLNSDSLYCCDPVFGDKHDEDENGHIFASADHPNIFLSHLLPLADIITPNLFELSVL
SGSQICNYDDIITACKKLISKTGNHNQIIIVTSVSFSKDKTGIAIYHHGNFSYLESPKYKVQPKVSGSGDITAAMFLSYL
LKGKNLDETLKAVTQCLDGIFRTTHQLNTDELALIQAQEYIR

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxamine [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505701, Length=308, Percent_Identity=30.8441558441558, Blast_Score=142, Evalue=3e-34,
Organism=Escherichia coli, GI1787924, Length=280, Percent_Identity=35, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1788758, Length=269, Percent_Identity=32.7137546468402, Blast_Score=128, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17507759, Length=287, Percent_Identity=32.0557491289199, Blast_Score=144, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI17507757, Length=297, Percent_Identity=31.3131313131313, Blast_Score=139, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6324354, Length=282, Percent_Identity=32.6241134751773, Blast_Score=119, Evalue=6e-28,
Organism=Saccharomyces cerevisiae, GI6320806, Length=249, Percent_Identity=34.136546184739, Blast_Score=112, Evalue=5e-26,
Organism=Drosophila melanogaster, GI45553007, Length=264, Percent_Identity=29.9242424242424, Blast_Score=138, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 31216; Mature: 31085

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKIPKVLSIQSHVAYGYAGNKAAVFPMQKLGIEVSPIYTVQLSNHTQYDFYKGSFFSA
CCCCCCHHHHHHHHEEEEECCCCEEEEEHHHHCEEECCEEEEEECCCCCCEEECCCCCCH
EDIQNVIDGMIANGFLAQQNAILSGYIGNLEIAKVIANTVIELKKLNSDSLYCCDPVFGD
HHHHHHHHHHHHCCCHHHCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCC
KHDEDENGHIFASADHPNIFLSHLLPLADIITPNLFELSVLSGSQICNYDDIITACKKLI
CCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHH
SKTGNHNQIIIVTSVSFSKDKTGIAIYHHGNFSYLESPKYKVQPKVSGSGDITAAMFLSY
HCCCCCCEEEEEEEEECCCCCCCEEEEECCCCCEECCCCEEEEECCCCCCCHHHHHHHHH
LLKGKNLDETLKAVTQCLDGIFRTTHQLNTDELALIQAQEYIR
HHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHCC
>Mature Secondary Structure 
SLKIPKVLSIQSHVAYGYAGNKAAVFPMQKLGIEVSPIYTVQLSNHTQYDFYKGSFFSA
CCCCCHHHHHHHHEEEEECCCCEEEEEHHHHCEEECCEEEEEECCCCCCEEECCCCCCH
EDIQNVIDGMIANGFLAQQNAILSGYIGNLEIAKVIANTVIELKKLNSDSLYCCDPVFGD
HHHHHHHHHHHHCCCHHHCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCC
KHDEDENGHIFASADHPNIFLSHLLPLADIITPNLFELSVLSGSQICNYDDIITACKKLI
CCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHH
SKTGNHNQIIIVTSVSFSKDKTGIAIYHHGNFSYLESPKYKVQPKVSGSGDITAAMFLSY
HCCCCCCEEEEEEEEECCCCCCCEEEEECCCCCEECCCCEEEEECCCCCCCHHHHHHHHH
LLKGKNLDETLKAVTQCLDGIFRTTHQLNTDELALIQAQEYIR
HHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA