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The map label for this gene is plsC [C]

Identifier: 89255527

GI number: 89255527

Start: 82083

End: 82823

Strand: Reverse

Name: plsC [C]

Synonym: FTL_0087

Alternate gene names: 89255527

Gene position: 82823-82083 (Counterclockwise)

Preceding gene: 89255528

Following gene: 89255524

Centisome position: 4.37

GC content: 34.41

Gene sequence:

>741_bases
ATGAAAAAGATAGTTCATCTATTATTAGTAGCAAGAATGCAAGTTTTTAAGGTATATGCATATATAGTGTTACTGCTATG
CTGTATTTTAATGAATCTAGTTGGGGTTTTAGGTGCCTCTCTAAAAGTTAGACTATTTGTCTGTTGGATATGGTCTTGCT
TATACCGCCTAGGCGTACTTGTTCTATTACAGATATATGTAAAAATAGATGGTAAAGAGAATATTCCTAACTATCCATGT
ATCTATGTTTCTAAACACCAGTCTATGCTTGAGACTTTTGTATTTTATGGTCTGGTACGCAATTGTTGTTTTGTCATGAA
GCAAGAACTCCTTGAGAAACCTATATTTGGTAAGGCTAATACTTTTGCTGAAGCAATAGGAATAGATAGATCTAATGGAC
TTTCGGCAATTAAGAAAGTGCTCGAAGATGGTAAAGATAGAGTCGAAAATAAAAACCTTAGTATTGTGATATTTCCTGAG
GGGACGAGGGTTCCTGTAGGTGAGTATCCAAAATTTCATCGCTCAGCAATGAAATTGGCAACTGTTACGAACATACCAAT
TATACCTGTAGCGCATAATTTTGGTGTTTATTTTGGACGTAAAAAAGGCGATTTTGTTAAGCCTGGTATTGCTAGAATGT
CTTTTGAGAAAGCTATAGACCCTAAAAACTATTCTGTCGCTGAATTAAAAGATATGTGTTATGACATCATTAATGATAAA
ACCAAATCTTTCGGTGGCTAA

Upstream 100 bases:

>100_bases
ATAGATCCTAGAGACTTTGATTCAAAAACGCTAACGAGCTATTGTCATAAGGTTATAACTGAGAAAACTAAAGAGTTTAA
CGGTTAAAAGAGGTAAACAG

Downstream 100 bases:

>100_bases
ATTTCTTATTTGATACAAAATTCAGCGATAATGGGATTATGATCAGATATTTTTTTACAATCTAGCACTGCAGCTTTTTC
AAGGCTTAAACCTCGATACA

Product: acetyltransferase protein

Products: CoA +diacyl-sn-glycerol phosphate [C]

Alternate protein names: 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase; Acyltransferase; 1-Acylglycerol-3-Phosphate O-Acyltransferase; 1-Acyl-Sn-Glycerol-3-Phosphate Acetyltransferase; Acyltransferase Domain Protein; Acyltransferase Family Protein; N-Acylhomoserine Lactone Synthase; 1-Acyl-SN-Glycerol-3-Phosphate Acyltransferase; HdtS Protein; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Protein; Bifunctional Phospholipid Biosynthesis PlsC; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferases; Protoheme IX Farnesyltransferase; HAD Family Hydrolase; Phospholipid And Glycerol Acyltransferase; Acyltransferase Domain-Containing Protein; AMP-Dependent Synthetase And Ligase; Transferase; Phospholipids Biosynthesis-Related Protein; Scaffold Protein; Acylhomoserine Lactone Synthase HdtS; [Acyl-]Glycerolphosphate Acyltransferase; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Alpha; Acetyltransferase Protein; Acetyltransferase; Phospholipid Biosynthesis-Related Acyltransferase; Acyltransferase Family; LPA Acyltransferase Protein

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MKKIVHLLLVARMQVFKVYAYIVLLLCCILMNLVGVLGASLKVRLFVCWIWSCLYRLGVLVLLQIYVKIDGKENIPNYPC
IYVSKHQSMLETFVFYGLVRNCCFVMKQELLEKPIFGKANTFAEAIGIDRSNGLSAIKKVLEDGKDRVENKNLSIVIFPE
GTRVPVGEYPKFHRSAMKLATVTNIPIIPVAHNFGVYFGRKKGDFVKPGIARMSFEKAIDPKNYSVAELKDMCYDIINDK
TKSFGG

Sequences:

>Translated_246_residues
MKKIVHLLLVARMQVFKVYAYIVLLLCCILMNLVGVLGASLKVRLFVCWIWSCLYRLGVLVLLQIYVKIDGKENIPNYPC
IYVSKHQSMLETFVFYGLVRNCCFVMKQELLEKPIFGKANTFAEAIGIDRSNGLSAIKKVLEDGKDRVENKNLSIVIFPE
GTRVPVGEYPKFHRSAMKLATVTNIPIIPVAHNFGVYFGRKKGDFVKPGIARMSFEKAIDPKNYSVAELKDMCYDIINDK
TKSFGG
>Mature_246_residues
MKKIVHLLLVARMQVFKVYAYIVLLLCCILMNLVGVLGASLKVRLFVCWIWSCLYRLGVLVLLQIYVKIDGKENIPNYPC
IYVSKHQSMLETFVFYGLVRNCCFVMKQELLEKPIFGKANTFAEAIGIDRSNGLSAIKKVLEDGKDRVENKNLSIVIFPE
GTRVPVGEYPKFHRSAMKLATVTNIPIIPVAHNFGVYFGRKKGDFVKPGIARMSFEKAIDPKNYSVAELKDMCYDIINDK
TKSFGG

Specific function: Converts Lysophosphatidic Acid (Lpa) Into Phosphatidic Acid By Incorporating An Acyl Moiety At The 2 Position. This Enzyme Can Utilize Either Acyl-CoA Or Acyl-Acyl Carrier Protein As The Fatty Acyl Donor. [C]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6041665, Length=160, Percent_Identity=30, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17564032, Length=164, Percent_Identity=32.9268292682927, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320151, Length=205, Percent_Identity=29.2682926829268, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641614, Length=145, Percent_Identity=32.4137931034483, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24641612, Length=145, Percent_Identity=32.4137931034483, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.51 [C]

Molecular weight: Translated: 27858; Mature: 27858

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIVHLLLVARMQVFKVYAYIVLLLCCILMNLVGVLGASLKVRLFVCWIWSCLYRLGVL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
VLLQIYVKIDGKENIPNYPCIYVSKHQSMLETFVFYGLVRNCCFVMKQELLEKPIFGKAN
HHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
TFAEAIGIDRSNGLSAIKKVLEDGKDRVENKNLSIVIFPEGTRVPVGEYPKFHRSAMKLA
HHHHHHCCCCCCCHHHHHHHHHCCHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHH
TVTNIPIIPVAHNFGVYFGRKKGDFVKPGIARMSFEKAIDPKNYSVAELKDMCYDIINDK
HHCCCCEEEEECCCCEEECCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCH
TKSFGG
HHCCCC
>Mature Secondary Structure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HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acyl-CoA; acyl-sn-glycerol phosphate [C]

Specific reaction: Acyl-CoA + acyl-sn-glycerol phosphate = CoA +diacyl-sn-glycerol phosphate [C]

General reaction: Acyl group transfer [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA