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The map label for this gene is ribD [H]

Identifier: 89255521

GI number: 89255521

Start: 74537

End: 75604

Strand: Reverse

Name: ribD [H]

Synonym: FTL_0078

Alternate gene names: 89255521

Gene position: 75604-74537 (Counterclockwise)

Preceding gene: 89255522

Following gene: 89255520

Centisome position: 3.99

GC content: 34.08

Gene sequence:

>1068_bases
ATGAAAAATATCGATAAATATTATATGCAACAAGCACTTACTCTAGCAAATAGAGGTAGACTTACAGTATCACCTAATCC
AATGGTTGGTTGCATAATAGTAAAAAATGGTGCAATTATCTCGGAAGGTTGGCATGAAACTGTAGGAGAAGCGCATGCAG
AGGTTCACGCACTGACAAAAGCGGTTGATAAAGCAAAAGGAGCTACAGCATACGTAACACTAGAACCATGCTGTCACTGT
GGAAGAACTCCTCCCTGTACTGATACCATAATCAAAGCTGGGATAAAAAAAGTAATTATTGCTACTCTTGATCCAAACCC
TAAAGTTGCTGGCAAAGGCGTCGAAAGACTCAAAAATGCTGGTATAACAGTCGAAGTAGGCTTACTAGAGAAACAAGCAC
AAGAGTTAAATAAAATATTTTTTCATTATCAAACAACCAAAAAACCTTTTGTTTATGCAAAATGGGCTATGTCATTAGAT
GGTAAAATAGCTGTTAATGATGGTGACTCAAAAAAAATAAGCTCACATCAAGCATTCGTAAATACTCATGAATTGCGCAA
TATTTGTGACGCTATCTTAATTGGCAAGCAAACTCTAATTGATGACAATCCAAGTCTTGATGTAAGAATAAATATCAATA
AAATAAAACATTCAACTAGATTTATACTTGCTAATCATCTGACAACAATAAATCATAATTGGCGAGTTTTAGATCAAAGG
CATGCCAAAACGATTTTTGTTTGTTCAAAGATCTCTGCACGAGTAGCAACCAAGCTTAACCAACTTGGCATTGAATATTG
GCTATTACCACAAAGTCAACATCAGGTTTGTTTAGATACCTTACTTGAGAAGATGGGTAAGATTGGAATAACTAGTCTTC
TTGTTGAAGGTGGTAATAAAACCCTAAATAGTTTTATTAATCAAAAACTTGTTAATGAATTTTATACATACTTAGCTCCG
GTAATAATAGCTGATTATAACCCCAAACAGCAGCTAAGCTTCAATCAAATCTCTGTAAGAGAGGATATAATAATAAACTC
TTGTTTTAAGGAAAATTCTAATGTTTAG

Upstream 100 bases:

>100_bases
ATTACTGTGGCTATAAATATAGTTTTATAGTCTATTGTATTTTTATAGTAATAATACTTCCTTGGTCCTGCCCTAACTGT
AAGTAAATATAAATGGGCAA

Downstream 100 bases:

>100_bases
TGGCATAGTTCAGCAACTAGGAACAATTAAAAAAATAACAACTAAAGATAGTCTAAAAACTTTTTGTATCAAATTTGATA
ATAGTCTTCAATGTAGCATT

Product: riboflavin biosynthesis protein ribD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MKNIDKYYMQQALTLANRGRLTVSPNPMVGCIIVKNGAIISEGWHETVGEAHAEVHALTKAVDKAKGATAYVTLEPCCHC
GRTPPCTDTIIKAGIKKVIIATLDPNPKVAGKGVERLKNAGITVEVGLLEKQAQELNKIFFHYQTTKKPFVYAKWAMSLD
GKIAVNDGDSKKISSHQAFVNTHELRNICDAILIGKQTLIDDNPSLDVRININKIKHSTRFILANHLTTINHNWRVLDQR
HAKTIFVCSKISARVATKLNQLGIEYWLLPQSQHQVCLDTLLEKMGKIGITSLLVEGGNKTLNSFINQKLVNEFYTYLAP
VIIADYNPKQQLSFNQISVREDIIINSCFKENSNV

Sequences:

>Translated_355_residues
MKNIDKYYMQQALTLANRGRLTVSPNPMVGCIIVKNGAIISEGWHETVGEAHAEVHALTKAVDKAKGATAYVTLEPCCHC
GRTPPCTDTIIKAGIKKVIIATLDPNPKVAGKGVERLKNAGITVEVGLLEKQAQELNKIFFHYQTTKKPFVYAKWAMSLD
GKIAVNDGDSKKISSHQAFVNTHELRNICDAILIGKQTLIDDNPSLDVRININKIKHSTRFILANHLTTINHNWRVLDQR
HAKTIFVCSKISARVATKLNQLGIEYWLLPQSQHQVCLDTLLEKMGKIGITSLLVEGGNKTLNSFINQKLVNEFYTYLAP
VIIADYNPKQQLSFNQISVREDIIINSCFKENSNV
>Mature_355_residues
MKNIDKYYMQQALTLANRGRLTVSPNPMVGCIIVKNGAIISEGWHETVGEAHAEVHALTKAVDKAKGATAYVTLEPCCHC
GRTPPCTDTIIKAGIKKVIIATLDPNPKVAGKGVERLKNAGITVEVGLLEKQAQELNKIFFHYQTTKKPFVYAKWAMSLD
GKIAVNDGDSKKISSHQAFVNTHELRNICDAILIGKQTLIDDNPSLDVRININKIKHSTRFILANHLTTINHNWRVLDQR
HAKTIFVCSKISARVATKLNQLGIEYWLLPQSQHQVCLDTLLEKMGKIGITSLLVEGGNKTLNSFINQKLVNEFYTYLAP
VIIADYNPKQQLSFNQISVREDIIINSCFKENSNV

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=333, Percent_Identity=39.9399399399399, Blast_Score=247, Evalue=9e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 39570; Mature: 39570

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIDKYYMQQALTLANRGRLTVSPNPMVGCIIVKNGAIISEGWHETVGEAHAEVHALTK
CCCHHHHHHHHHHHHHCCCEEEECCCCEEEEEEEECCEEEECCHHHHHHHHHHHHHHHHH
AVDKAKGATAYVTLEPCCHCGRTPPCTDTIIKAGIKKVIIATLDPNPKVAGKGVERLKNA
HHHHCCCCEEEEEECHHHCCCCCCCCHHHHHHHCHHEEEEEEECCCCCCCCCHHHHHHHC
GITVEVGLLEKQAQELNKIFFHYQTTKKPFVYAKWAMSLDGKIAVNDGDSKKISSHQAFV
CCEEEEHHHHHHHHHHHHHEEEEECCCCCEEEEEEEECCCCEEEECCCCCCCCCCHHHHH
NTHELRNICDAILIGKQTLIDDNPSLDVRININKIKHSTRFILANHLTTINHNWRVLDQR
HHHHHHHHHHHHHHCCHHEECCCCCEEEEEEEHHHCCCHHEEEECCEEEECCCEEEEECC
HAKTIFVCSKISARVATKLNQLGIEYWLLPQSQHQVCLDTLLEKMGKIGITSLLVEGGNK
CCCEEEEEHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCCHHHEEEECCCH
TLNSFINQKLVNEFYTYLAPVIIADYNPKQQLSFNQISVREDIIINSCFKENSNV
HHHHHHHHHHHHHHHHHHHHEEEECCCCHHCCCCCCEEHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKNIDKYYMQQALTLANRGRLTVSPNPMVGCIIVKNGAIISEGWHETVGEAHAEVHALTK
CCCHHHHHHHHHHHHHCCCEEEECCCCEEEEEEEECCEEEECCHHHHHHHHHHHHHHHHH
AVDKAKGATAYVTLEPCCHCGRTPPCTDTIIKAGIKKVIIATLDPNPKVAGKGVERLKNA
HHHHCCCCEEEEEECHHHCCCCCCCCHHHHHHHCHHEEEEEEECCCCCCCCCHHHHHHHC
GITVEVGLLEKQAQELNKIFFHYQTTKKPFVYAKWAMSLDGKIAVNDGDSKKISSHQAFV
CCEEEEHHHHHHHHHHHHHEEEEECCCCCEEEEEEEECCCCEEEECCCCCCCCCCHHHHH
NTHELRNICDAILIGKQTLIDDNPSLDVRININKIKHSTRFILANHLTTINHNWRVLDQR
HHHHHHHHHHHHHHCCHHEECCCCCEEEEEEEHHHCCCHHEEEECCEEEECCCEEEEECC
HAKTIFVCSKISARVATKLNQLGIEYWLLPQSQHQVCLDTLLEKMGKIGITSLLVEGGNK
CCCEEEEEHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCCHHHEEEECCCH
TLNSFINQKLVNEFYTYLAPVIIADYNPKQQLSFNQISVREDIIINSCFKENSNV
HHHHHHHHHHHHHHHHHHHHEEEECCCCHHCCCCCCEEHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]