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The map label for this gene is pyrF [H]

Identifier: 89255492

GI number: 89255492

Start: 47960

End: 48592

Strand: Direct

Name: pyrF [H]

Synonym: FTL_0045

Alternate gene names: 89255492

Gene position: 47960-48592 (Clockwise)

Preceding gene: 89255490

Following gene: 89255493

Centisome position: 2.53

GC content: 35.23

Gene sequence:

>633_bases
ATGAAAATAATGTTCTCAGCAGATGGTATCTCTAAGTCAGATTTAGAGAAAACAGCCACTGTATCAAAGTATGTTGACTG
TGTTAAGATTGGTCATATTCTATGCTCAACGTTATCTTTTAAAGAAATTCATGAGCTAGTAGGCGACAAAGATATTTTCC
TAGACTTTAAGTTACACGATATCCCAAATACAGTTAAAACTGCAATTGAAAATTATTCAAAAGCTATTCCAAATTTTAAA
TATTTTACATTTCATGGTACTGCTAGTGATGAGATGATAAAAGCAGCCCTTACGGCAGATACTCAAGCTATACCATTAGC
TGTGATTACACTTAGTAGTGATGCTAATTTTGATAAGGCAGATAGCCTTGCTAAATTTCAAAGATGTGTGGATTTAGGTG
TGGAAAACTTTATATGTCATCCACATTTAGTTGCTGATGTCAGAGCTAAATTTGGCGATAAAATCAAGCTATATGTCCCA
GGTGTAAGGCTTGAGAGTGATCTAAGTGATGATCATTTTAACGCTTTGACCCCTAAAAAAGCCAAAGAGCTTGGCGTTGA
TTACATTATTGTAGGTAGGCCGCTATTACGCGCTGAAAATATCGTTGAGAAGCTAAAAGAGTTTGAGTGCTAA

Upstream 100 bases:

>100_bases
CTTGAATATATGAAAGTAACAAATTTAAAATATAGTTTACTATCACCACAAATTAAACTAATATATAGTTTCAACATCGA
TTAATCATTTGAGAAACTCA

Downstream 100 bases:

>100_bases
GATGCAAAATCAAGATCTTAAAAGAATAATAATCTCGCCACCGTTTGGTAAATATCTTAAATTTAAAGAAACTTCGAATG
TTTATGGTTCTTTTACTGTG

Product: orotidine 5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase [H]

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MKIMFSADGISKSDLEKTATVSKYVDCVKIGHILCSTLSFKEIHELVGDKDIFLDFKLHDIPNTVKTAIENYSKAIPNFK
YFTFHGTASDEMIKAALTADTQAIPLAVITLSSDANFDKADSLAKFQRCVDLGVENFICHPHLVADVRAKFGDKIKLYVP
GVRLESDLSDDHFNALTPKKAKELGVDYIIVGRPLLRAENIVEKLKEFEC

Sequences:

>Translated_210_residues
MKIMFSADGISKSDLEKTATVSKYVDCVKIGHILCSTLSFKEIHELVGDKDIFLDFKLHDIPNTVKTAIENYSKAIPNFK
YFTFHGTASDEMIKAALTADTQAIPLAVITLSSDANFDKADSLAKFQRCVDLGVENFICHPHLVADVRAKFGDKIKLYVP
GVRLESDLSDDHFNALTPKKAKELGVDYIIVGRPLLRAENIVEKLKEFEC
>Mature_210_residues
MKIMFSADGISKSDLEKTATVSKYVDCVKIGHILCSTLSFKEIHELVGDKDIFLDFKLHDIPNTVKTAIENYSKAIPNFK
YFTFHGTASDEMIKAALTADTQAIPLAVITLSSDANFDKADSLAKFQRCVDLGVENFICHPHLVADVRAKFGDKIKLYVP
GVRLESDLSDDHFNALTPKKAKELGVDYIIVGRPLLRAENIVEKLKEFEC

Specific function: Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) [H]

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787537, Length=201, Percent_Identity=28.8557213930348, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR014732
- InterPro:   IPR018089
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.23 [H]

Molecular weight: Translated: 23399; Mature: 23399

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00156 OMPDECASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIMFSADGISKSDLEKTATVSKYVDCVKIGHILCSTLSFKEIHELVGDKDIFLDFKLHD
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEEEECC
IPNTVKTAIENYSKAIPNFKYFTFHGTASDEMIKAALTADTQAIPLAVITLSSDANFDKA
CCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCHH
DSLAKFQRCVDLGVENFICHPHLVADVRAKFGDKIKLYVPGVRLESDLSDDHFNALTPKK
HHHHHHHHHHHHCHHHHCCCCHHHHHHHHHCCCEEEEEECCEEECCCCCCCCCCCCCCHH
AKELGVDYIIVGRPLLRAENIVEKLKEFEC
HHHCCCCEEEECCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIMFSADGISKSDLEKTATVSKYVDCVKIGHILCSTLSFKEIHELVGDKDIFLDFKLHD
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEEEECC
IPNTVKTAIENYSKAIPNFKYFTFHGTASDEMIKAALTADTQAIPLAVITLSSDANFDKA
CCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCHH
DSLAKFQRCVDLGVENFICHPHLVADVRAKFGDKIKLYVPGVRLESDLSDDHFNALTPKK
HHHHHHHHHHHHCHHHHCCCCHHHHHHHHHCCCEEEEEECCEEECCCCCCCCCCCCCCHH
AKELGVDYIIVGRPLLRAENIVEKLKEFEC
HHHCCCCEEEECCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA