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The map label for this gene is carA [H]

Identifier: 89255477

GI number: 89255477

Start: 30723

End: 31889

Strand: Reverse

Name: carA [H]

Synonym: FTL_0030

Alternate gene names: 89255477

Gene position: 31889-30723 (Counterclockwise)

Preceding gene: 89255479

Following gene: 89255476

Centisome position: 1.68

GC content: 37.36

Gene sequence:

>1167_bases
ATGATATTAGCTAACGATATGACTAATGCGATATTGGTTTTTCCAGATGGTACATACTATCTAGGTAGATCAATAGGGGT
TCGTGGTTGGACAGACGGCGAAATTTGTTTCAATACATCAATGACAGGTTACCAAGAGACTCTAACAGATCCATCTTATG
CTGGTCAGATTATAACTTTTACATTCCCACACATAGGTAATGTCGGTATCAATAATGAGGATAATGAATCACTTGGTGTA
TTTGCTAAAGGTCTAATCGTACGTGAGAACCTTACAAACCCATCAAATTTTAGAGCTAAAAAGCATATAGATACATGGCT
AAAAAATAGAAATATAGTCGGTATCTGTGGTGTTGATACGCGTGCAATCGTACGTAAAGTGCGTAAAGAAGGCGCGGTAA
GAGTTGCTATACTTTCGGTCAAACCAGGTGAGTTTTTGGATGCAAACTATGTCAGATCGCGTATCAAAAATAAATCTAAC
CTAAATGGTAGAGATCTAGCTATCAGTGTGACTACAAACAGAGAATATGACTGGAATGAGCATACTTTCACACTAGGTCA
ACAAGTATACAAACAGCAACAAAGCTACAAATATAGTGTTGTAGTTATCGATTATGGTGTCAAGTACAATATCTTAAGAA
ACCTAGTAGATGCTGGTTTTAAGGTAACTGTAGTACCTGCTGATAGTACTTATGAAGATATTATGAAGCATAACCCTGAT
GGGGTGTTTTTATCAAATGGTCCTGGAGATCCATTTGCTACCTCTGACTATACTATGCCTGTTATAAAAAAGCTTCTAGA
AGTCAAAATGCCAATATTTGGTATCTGTCTGGGTAACCAATTATTAGCCCTAGCTGCTGGTCTAAAAACTAAAAAAATGC
ATAAAGGTCACCGTGGTGTAAACCAACCAGTACTTGATGCCAATACTAAAAAAGTTCTTATTACAAGCCAAAACCATGGC
TTTGTGGTTTGTGATGATAATGTTCCTGATAATATTCAAATTCATATGAGCTCACTTTTTGATGGTACTGTTGAGGGATT
ACGATTTAAAGACAGGCCAGCATTTGCCGTGCAGTACCACCCAGAGAGCTCACCAGGTCCGCATGACTGTAAGTATTTGT
TTAATGAATTTGCCGAGATGATAGCAGAAAGTAAGAAAGGGAATTAA

Upstream 100 bases:

>100_bases
TTCAATTTGCCTATTAACTTTGTAAAAAAGTAATGACAAAAAAGTTTTTCAAAATACTTTTTTCTTCCAGTTTCATTCAT
CACAGTAAGGTTGTTTTATT

Downstream 100 bases:

>100_bases
TAACATGCCAAAAATAACAGATATAAAAAGTATTTTAGTTTTAGGTGCTGGTCCAATAGTTATCGGTCAAGCATGTGAGT
TTGACTACTCAGGAACTCAA

Product: carbamoyl phosphate synthase small subunit

Products: NA

Alternate protein names: Carbamoyl-phosphate synthetase glutamine chain [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MILANDMTNAILVFPDGTYYLGRSIGVRGWTDGEICFNTSMTGYQETLTDPSYAGQIITFTFPHIGNVGINNEDNESLGV
FAKGLIVRENLTNPSNFRAKKHIDTWLKNRNIVGICGVDTRAIVRKVRKEGAVRVAILSVKPGEFLDANYVRSRIKNKSN
LNGRDLAISVTTNREYDWNEHTFTLGQQVYKQQQSYKYSVVVIDYGVKYNILRNLVDAGFKVTVVPADSTYEDIMKHNPD
GVFLSNGPGDPFATSDYTMPVIKKLLEVKMPIFGICLGNQLLALAAGLKTKKMHKGHRGVNQPVLDANTKKVLITSQNHG
FVVCDDNVPDNIQIHMSSLFDGTVEGLRFKDRPAFAVQYHPESSPGPHDCKYLFNEFAEMIAESKKGN

Sequences:

>Translated_388_residues
MILANDMTNAILVFPDGTYYLGRSIGVRGWTDGEICFNTSMTGYQETLTDPSYAGQIITFTFPHIGNVGINNEDNESLGV
FAKGLIVRENLTNPSNFRAKKHIDTWLKNRNIVGICGVDTRAIVRKVRKEGAVRVAILSVKPGEFLDANYVRSRIKNKSN
LNGRDLAISVTTNREYDWNEHTFTLGQQVYKQQQSYKYSVVVIDYGVKYNILRNLVDAGFKVTVVPADSTYEDIMKHNPD
GVFLSNGPGDPFATSDYTMPVIKKLLEVKMPIFGICLGNQLLALAAGLKTKKMHKGHRGVNQPVLDANTKKVLITSQNHG
FVVCDDNVPDNIQIHMSSLFDGTVEGLRFKDRPAFAVQYHPESSPGPHDCKYLFNEFAEMIAESKKGN
>Mature_388_residues
MILANDMTNAILVFPDGTYYLGRSIGVRGWTDGEICFNTSMTGYQETLTDPSYAGQIITFTFPHIGNVGINNEDNESLGV
FAKGLIVRENLTNPSNFRAKKHIDTWLKNRNIVGICGVDTRAIVRKVRKEGAVRVAILSVKPGEFLDANYVRSRIKNKSN
LNGRDLAISVTTNREYDWNEHTFTLGQQVYKQQQSYKYSVVVIDYGVKYNILRNLVDAGFKVTVVPADSTYEDIMKHNPD
GVFLSNGPGDPFATSDYTMPVIKKLLEVKMPIFGICLGNQLLALAAGLKTKKMHKGHRGVNQPVLDANTKKVLITSQNHG
FVVCDDNVPDNIQIHMSSLFDGTVEGLRFKDRPAFAVQYHPESSPGPHDCKYLFNEFAEMIAESKKGN

Specific function: Arginine biosynthesis. Pyrimidine biosynthesis; first step. [C]

COG id: COG0505

COG function: function code EF; Carbamoylphosphate synthase small subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=393, Percent_Identity=36.8956743002545, Blast_Score=235, Evalue=4e-62,
Organism=Homo sapiens, GI169790915, Length=397, Percent_Identity=34.7607052896725, Blast_Score=208, Evalue=9e-54,
Organism=Homo sapiens, GI21361331, Length=397, Percent_Identity=34.7607052896725, Blast_Score=208, Evalue=9e-54,
Organism=Escherichia coli, GI1786215, Length=382, Percent_Identity=49.2146596858639, Blast_Score=377, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI193204318, Length=395, Percent_Identity=33.6708860759494, Blast_Score=219, Evalue=2e-57,
Organism=Saccharomyces cerevisiae, GI6324878, Length=396, Percent_Identity=35.3535353535354, Blast_Score=211, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6322331, Length=393, Percent_Identity=33.3333333333333, Blast_Score=208, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6322638, Length=175, Percent_Identity=26.8571428571429, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI45555749, Length=401, Percent_Identity=35.1620947630923, Blast_Score=220, Evalue=1e-57,
Organism=Drosophila melanogaster, GI24642586, Length=401, Percent_Identity=35.1620947630923, Blast_Score=220, Evalue=1e-57,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2599 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR006274
- InterPro:   IPR002474
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF00988 CPSase_sm_chain; PF00117 GATase [H]

EC number: =6.3.5.5 [H]

Molecular weight: Translated: 43265; Mature: 43265

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILANDMTNAILVFPDGTYYLGRSIGVRGWTDGEICFNTSMTGYQETLTDPSYAGQIITF
CEEECCCCCEEEEEECCCEEECCCCCCCCCCCCCEEEECCCCCHHHHCCCCCCCCEEEEE
TFPHIGNVGINNEDNESLGVFAKGLIVRENLTNPSNFRAKKHIDTWLKNRNIVGICGVDT
ECCCCCCCCCCCCCCCCCEEEEECEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCH
RAIVRKVRKEGAVRVAILSVKPGEFLDANYVRSRIKNKSNLNGRDLAISVTTNREYDWNE
HHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCC
HTFTLGQQVYKQQQSYKYSVVVIDYGVKYNILRNLVDAGFKVTVVPADSTYEDIMKHNPD
CEEHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHCCCC
GVFLSNGPGDPFATSDYTMPVIKKLLEVKMPIFGICLGNQLLALAAGLKTKKMHKGHRGV
EEEEECCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCHHHHHHCCCCC
NQPVLDANTKKVLITSQNHGFVVCDDNVPDNIQIHMSSLFDGTVEGLRFKDRPAFAVQYH
CCCEECCCCCEEEEEECCCCEEEECCCCCCCEEEEEEHHCCCHHHCCEECCCCCEEEEEC
PESSPGPHDCKYLFNEFAEMIAESKKGN
CCCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MILANDMTNAILVFPDGTYYLGRSIGVRGWTDGEICFNTSMTGYQETLTDPSYAGQIITF
CEEECCCCCEEEEEECCCEEECCCCCCCCCCCCCEEEECCCCCHHHHCCCCCCCCEEEEE
TFPHIGNVGINNEDNESLGVFAKGLIVRENLTNPSNFRAKKHIDTWLKNRNIVGICGVDT
ECCCCCCCCCCCCCCCCCEEEEECEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCH
RAIVRKVRKEGAVRVAILSVKPGEFLDANYVRSRIKNKSNLNGRDLAISVTTNREYDWNE
HHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCC
HTFTLGQQVYKQQQSYKYSVVVIDYGVKYNILRNLVDAGFKVTVVPADSTYEDIMKHNPD
CEEHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHCCCC
GVFLSNGPGDPFATSDYTMPVIKKLLEVKMPIFGICLGNQLLALAAGLKTKKMHKGHRGV
EEEEECCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCHHHHHHCCCCC
NQPVLDANTKKVLITSQNHGFVVCDDNVPDNIQIHMSSLFDGTVEGLRFKDRPAFAVQYH
CCCEECCCCCEEEEEECCCCEEEECCCCCCCEEEEEEHHCCCHHHCCEECCCCCEEEEEC
PESSPGPHDCKYLFNEFAEMIAESKKGN
CCCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA