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The map label for this gene is hipO [H]

Identifier: 89056641

GI number: 89056641

Start: 4261901

End: 4263046

Strand: Direct

Name: hipO [H]

Synonym: Jann_4150

Alternate gene names: 89056641

Gene position: 4261901-4263046 (Clockwise)

Preceding gene: 89056639

Following gene: 89056642

Centisome position: 98.7

GC content: 62.04

Gene sequence:

>1146_bases
TTGACCGATCAAGACTTGGTAGACCTGCGTCGCGCCTTTCACCGCGCGCCCGAACTTGGGTTTCAGGAGGATGTGACCAA
GGCCAGGATCGCCGATCTTCTGAGGGGGTTTGGCCTTGATGTGTATGAAGGTGCGGGCGTTGTCGGCGTCCTAAAGCGCG
GCTCTGGCAACCGTGCGATTGGACTGCGCGCGGATATGGATGCGCTGCCGATCCGGGAGACGAGTGCCCACGATTACACT
TCGGAAACGCCGGGCGTGATGCATGCCTGCGGCCATGATGGGCATATGACGATGCTTCTGGGGGCCGCCGAGAAACTGGC
CCGCGACGCGGCGTTCGATGGCACCGTCGTCTTCCTCTTCCAACCCAATGAAGAGCATGGCCTGGGTGCAAAGGCCATGC
TTGCAGAAGGCGTTCTGGAGCGGTTCCCGATGGAGGAGGTCTATGCCATCCACAACCTGTCGGGCGCATCCGTGGGCCAT
GTCTCGACGCGCGTGGGCCAGATTTGCTCCAGCGAAAGCCTATTCGAGATCCAGATCGTTGGTCAGGGCGGTCACGCCTC
CATGCCCCATGTCGGGCGCGATGCGATCACTGTGGGGGCCGAGATTGTTCTGGCCCTGCAAACCATCGTCGCGCGCAAGC
TGTCGCCGGGCGCGGGCGTTGTGGTGTCAGTGACAGAGTTCCTGACCGACGGGCAGCGCAACGTGCTGCCCAGCGTCGTG
ACGCTGAAAGGCGACGTACGCGCCCGCCTGGCCCCGGATCGAGAGGAGGTCGCCCGCCTGATGCGCCAGATTGCAGACGG
GATCGGTGCCGCCCATGGTGTCGCGGTCACCACCTCGTTCCAGACAGAATTCATTGAGACTATGAACGCCGCCATGCCGA
CGCAGGCTGTGATAGACGCCGCAACCGCGCAGGGATTAGGCGTCGACGGCACCTGTGACCCGATGAGTTTCTCGGAAGAT
TTTGCTCATTTCTCTGCCGCCGTGCCTGGGTGTTTTCTGATGTTGGGCAACGGGACGGATGGGCCCCATGGCCAACCCCT
TCACGCCTCAGACTATGATTTCAACGACGCACTCTTGCCCATCGGGCGGGACCTTTGGGTGCAACTGGTCTGCGATCGGC
TGCCTTCGGGAGGACATGATGTTTGA

Upstream 100 bases:

>100_bases
CGGCCGCCCGGAGGGACCTAAACCCTGCAGTTTGATCAGGTTTACGCCAGTTGCGGACCCCGCAACCTTCGTGTTTGTCT
ACTAAAAAGGGGAGATGCCG

Downstream 100 bases:

>100_bases
AGACCGGATAACCACGTTCCGCACCCGGATCGACGAGGCCGGGATTGACGTTGCGTTGATCACTGATGACGACGCGGTCT
ACTACCTGACGGGCTACTAC

Product: peptidase M20D, amidohydrolase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MTDQDLVDLRRAFHRAPELGFQEDVTKARIADLLRGFGLDVYEGAGVVGVLKRGSGNRAIGLRADMDALPIRETSAHDYT
SETPGVMHACGHDGHMTMLLGAAEKLARDAAFDGTVVFLFQPNEEHGLGAKAMLAEGVLERFPMEEVYAIHNLSGASVGH
VSTRVGQICSSESLFEIQIVGQGGHASMPHVGRDAITVGAEIVLALQTIVARKLSPGAGVVVSVTEFLTDGQRNVLPSVV
TLKGDVRARLAPDREEVARLMRQIADGIGAAHGVAVTTSFQTEFIETMNAAMPTQAVIDAATAQGLGVDGTCDPMSFSED
FAHFSAAVPGCFLMLGNGTDGPHGQPLHASDYDFNDALLPIGRDLWVQLVCDRLPSGGHDV

Sequences:

>Translated_381_residues
MTDQDLVDLRRAFHRAPELGFQEDVTKARIADLLRGFGLDVYEGAGVVGVLKRGSGNRAIGLRADMDALPIRETSAHDYT
SETPGVMHACGHDGHMTMLLGAAEKLARDAAFDGTVVFLFQPNEEHGLGAKAMLAEGVLERFPMEEVYAIHNLSGASVGH
VSTRVGQICSSESLFEIQIVGQGGHASMPHVGRDAITVGAEIVLALQTIVARKLSPGAGVVVSVTEFLTDGQRNVLPSVV
TLKGDVRARLAPDREEVARLMRQIADGIGAAHGVAVTTSFQTEFIETMNAAMPTQAVIDAATAQGLGVDGTCDPMSFSED
FAHFSAAVPGCFLMLGNGTDGPHGQPLHASDYDFNDALLPIGRDLWVQLVCDRLPSGGHDV
>Mature_380_residues
TDQDLVDLRRAFHRAPELGFQEDVTKARIADLLRGFGLDVYEGAGVVGVLKRGSGNRAIGLRADMDALPIRETSAHDYTS
ETPGVMHACGHDGHMTMLLGAAEKLARDAAFDGTVVFLFQPNEEHGLGAKAMLAEGVLERFPMEEVYAIHNLSGASVGHV
STRVGQICSSESLFEIQIVGQGGHASMPHVGRDAITVGAEIVLALQTIVARKLSPGAGVVVSVTEFLTDGQRNVLPSVVT
LKGDVRARLAPDREEVARLMRQIADGIGAAHGVAVTTSFQTEFIETMNAAMPTQAVIDAATAQGLGVDGTCDPMSFSEDF
AHFSAAVPGCFLMLGNGTDGPHGQPLHASDYDFNDALLPIGRDLWVQLVCDRLPSGGHDV

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=371, Percent_Identity=27.7628032345013, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 40361; Mature: 40230

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDQDLVDLRRAFHRAPELGFQEDVTKARIADLLRGFGLDVYEGAGVVGVLKRGSGNRAI
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEE
GLRADMDALPIRETSAHDYTSETPGVMHACGHDGHMTMLLGAAEKLARDAAFDGTVVFLF
EEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEHHHHHHHHHHHHCCCCCEEEEEE
QPNEEHGLGAKAMLAEGVLERFPMEEVYAIHNLSGASVGHVSTRVGQICSSESLFEIQIV
CCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEEE
GQGGHASMPHVGRDAITVGAEIVLALQTIVARKLSPGAGVVVSVTEFLTDGQRNVLPSVV
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHCCCCCCCCCCEE
TLKGDVRARLAPDREEVARLMRQIADGIGAAHGVAVTTSFQTEFIETMNAAMPTQAVIDA
EECCCCCEECCCCHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHCCCHHHHHHH
ATAQGLGVDGTCDPMSFSEDFAHFSAAVPGCFLMLGNGTDGPHGQPLHASDYDFNDALLP
HHHCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
IGRDLWVQLVCDRLPSGGHDV
CCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TDQDLVDLRRAFHRAPELGFQEDVTKARIADLLRGFGLDVYEGAGVVGVLKRGSGNRAI
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEE
GLRADMDALPIRETSAHDYTSETPGVMHACGHDGHMTMLLGAAEKLARDAAFDGTVVFLF
EEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEHHHHHHHHHHHHCCCCCEEEEEE
QPNEEHGLGAKAMLAEGVLERFPMEEVYAIHNLSGASVGHVSTRVGQICSSESLFEIQIV
CCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEEE
GQGGHASMPHVGRDAITVGAEIVLALQTIVARKLSPGAGVVVSVTEFLTDGQRNVLPSVV
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHCCCCCCCCCCEE
TLKGDVRARLAPDREEVARLMRQIADGIGAAHGVAVTTSFQTEFIETMNAAMPTQAVIDA
EECCCCCEECCCCHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHCCCHHHHHHH
ATAQGLGVDGTCDPMSFSEDFAHFSAAVPGCFLMLGNGTDGPHGQPLHASDYDFNDALLP
HHHCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
IGRDLWVQLVCDRLPSGGHDV
CCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]