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The map label for this gene is pepQ [H]

Identifier: 89056615

GI number: 89056615

Start: 4231954

End: 4233045

Strand: Direct

Name: pepQ [H]

Synonym: Jann_4124

Alternate gene names: 89056615

Gene position: 4231954-4233045 (Clockwise)

Preceding gene: 89056614

Following gene: 89056616

Centisome position: 98.01

GC content: 64.47

Gene sequence:

>1092_bases
ATGAATGCAGGGCTCGACGGATTGCTTCTGCTGCGTGCCCCCAATCTGGCCTACGCGACGGGGCTGTTTCTATCTGCCAA
CGAACGCCCCATGGGCGTCTGGCTGCCCATGGATGGTGACCCGATCCTGATGCTGCCAGGCCTGGAGCGGGAGAATGCCA
AGGGCACGGGGCTGACCGATCTGCGGTTCTATGACGAATTTCCGGGAAAGGAGCCGCCGGTGCTGTGGATGCTGGATCAG
ATCGGCCGCAAGCACATCGGAATCGACGCTCTGGATGCAGCGCTTCTGGATGCGGCGCGCGACAAGGCAGTGCGGATCGA
CCTGACCGATCACGCCATGGCCGCACGTACCATCAAGGAGCCCGAGGAAATCGCGCTGACGGTCGAGGCGGCGTCCTTCG
CGGACCTGTTTCTGACTCGTCTGCATGCGGCGGCGGGCGATATCATCAACCAAGGCGGGACGGAGGCCGATCTGATGGCC
GACGCCATGGCCCACGCACGCGGTGCTTTGATGGCCAAACACAAGCAGGCTTTTTCGGGCACGCCCATGGGCATCACCGC
GTCCGTCCATTCAGGGCCGCGCGCCGCTCTGCCCCATGGCGCGGTGCTGGAACGTGTGCCGCAACCCGGTGAGACGCTGA
TTGCGGGGATCGGGGCCAGTTTGGGCGGCTACCATGCCGAAAGCGGCGTGACCCTGATCGTAGGCAGCATCAGCGCGGAA
CAACGCCAGATCATGGCGGCCATGAAGGCGTGCAACGACGCGGGCGTAGCGGCTTGCGGGGCCCGCACGACCTGCACCCA
AGCCAATGATGCCGCATTGGATGCGCTGCGTGCCGCAGGTCTCGGCGACACCATACGTCACCGCATCGGCCATGGCATGG
GGCTGGAAGGACACGAAGACCCGTGGCTCGCCCCCGGCGATCCAACACCAATCCAGACCCATATGATTTTCTCCAACGAG
CCCGGCGTCTACCGGCCCGGGATCGACGGATACCGCACCATCAACACCATGATCGTGACCGAGGACGGCGTCGACATCCC
GTCCCGGTTCCAAGCCAACACGCCCATTGACGCCCGCGTCATCGCCCTTTGA

Upstream 100 bases:

>100_bases
CGCCGCTGGACGGACTTGGTCCCTACACGGGCAGCACGCTGTGACACCGCTGGAGCCCACTTTCTTCGCCCGCGCGCGAG
ATCGGCTACGTGCCCGCGCG

Downstream 100 bases:

>100_bases
AGGAGCCTGAGAGATGCCCGAACCCGCCTCCTGGAAATACCAGAAGATCACCAAGCCGATGTTCGAGGCCGAGGCCGTGG
ACTGCGTTTTCTTCGGACGG

Product: peptidase M24

Products: NA

Alternate protein names: X-Pro dipeptidase; Imidodipeptidase; Proline dipeptidase; Prolidase [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MNAGLDGLLLLRAPNLAYATGLFLSANERPMGVWLPMDGDPILMLPGLERENAKGTGLTDLRFYDEFPGKEPPVLWMLDQ
IGRKHIGIDALDAALLDAARDKAVRIDLTDHAMAARTIKEPEEIALTVEAASFADLFLTRLHAAAGDIINQGGTEADLMA
DAMAHARGALMAKHKQAFSGTPMGITASVHSGPRAALPHGAVLERVPQPGETLIAGIGASLGGYHAESGVTLIVGSISAE
QRQIMAAMKACNDAGVAACGARTTCTQANDAALDALRAAGLGDTIRHRIGHGMGLEGHEDPWLAPGDPTPIQTHMIFSNE
PGVYRPGIDGYRTINTMIVTEDGVDIPSRFQANTPIDARVIAL

Sequences:

>Translated_363_residues
MNAGLDGLLLLRAPNLAYATGLFLSANERPMGVWLPMDGDPILMLPGLERENAKGTGLTDLRFYDEFPGKEPPVLWMLDQ
IGRKHIGIDALDAALLDAARDKAVRIDLTDHAMAARTIKEPEEIALTVEAASFADLFLTRLHAAAGDIINQGGTEADLMA
DAMAHARGALMAKHKQAFSGTPMGITASVHSGPRAALPHGAVLERVPQPGETLIAGIGASLGGYHAESGVTLIVGSISAE
QRQIMAAMKACNDAGVAACGARTTCTQANDAALDALRAAGLGDTIRHRIGHGMGLEGHEDPWLAPGDPTPIQTHMIFSNE
PGVYRPGIDGYRTINTMIVTEDGVDIPSRFQANTPIDARVIAL
>Mature_363_residues
MNAGLDGLLLLRAPNLAYATGLFLSANERPMGVWLPMDGDPILMLPGLERENAKGTGLTDLRFYDEFPGKEPPVLWMLDQ
IGRKHIGIDALDAALLDAARDKAVRIDLTDHAMAARTIKEPEEIALTVEAASFADLFLTRLHAAAGDIINQGGTEADLMA
DAMAHARGALMAKHKQAFSGTPMGITASVHSGPRAALPHGAVLERVPQPGETLIAGIGASLGGYHAESGVTLIVGSISAE
QRQIMAAMKACNDAGVAACGARTTCTQANDAALDALRAAGLGDTIRHRIGHGMGLEGHEDPWLAPGDPTPIQTHMIFSNE
PGVYRPGIDGYRTINTMIVTEDGVDIPSRFQANTPIDARVIAL

Specific function: Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position [H]

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family. Archaeal-type prolidase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788728, Length=236, Percent_Identity=32.2033898305085, Blast_Score=102, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.13.9 [H]

Molecular weight: Translated: 38266; Mature: 38266

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAGLDGLLLLRAPNLAYATGLFLSANERPMGVWLPMDGDPILMLPGLERENAKGTGLTD
CCCCCCEEEEEECCCCCEEEEEEEECCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCEE
LRFYDEFPGKEPPVLWMLDQIGRKHIGIDALDAALLDAARDKAVRIDLTDHAMAARTIKE
EEEHHCCCCCCCCEEEEHHHCCCHHCCHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHCC
PEEIALTVEAASFADLFLTRLHAAAGDIINQGGTEADLMADAMAHARGALMAKHKQAFSG
CCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
TPMGITASVHSGPRAALPHGAVLERVPQPGETLIAGIGASLGGYHAESGVTLIVGSISAE
CCCEEEEECCCCCCCCCCCCHHHHHCCCCCHHHHEECCCCCCCEECCCCCEEEEECCCHH
QRQIMAAMKACNDAGVAACGARTTCTQANDAALDALRAAGLGDTIRHRIGHGMGLEGHED
HHHHHHHHHHCCCCCCEECCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCC
PWLAPGDPTPIQTHMIFSNEPGVYRPGIDGYRTINTMIVTEDGVDIPSRFQANTPIDARV
CCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCEEE
IAL
EEC
>Mature Secondary Structure
MNAGLDGLLLLRAPNLAYATGLFLSANERPMGVWLPMDGDPILMLPGLERENAKGTGLTD
CCCCCCEEEEEECCCCCEEEEEEEECCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCEE
LRFYDEFPGKEPPVLWMLDQIGRKHIGIDALDAALLDAARDKAVRIDLTDHAMAARTIKE
EEEHHCCCCCCCCEEEEHHHCCCHHCCHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHCC
PEEIALTVEAASFADLFLTRLHAAAGDIINQGGTEADLMADAMAHARGALMAKHKQAFSG
CCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
TPMGITASVHSGPRAALPHGAVLERVPQPGETLIAGIGASLGGYHAESGVTLIVGSISAE
CCCEEEEECCCCCCCCCCCCHHHHHCCCCCHHHHEECCCCCCCEECCCCCEEEEECCCHH
QRQIMAAMKACNDAGVAACGARTTCTQANDAALDALRAAGLGDTIRHRIGHGMGLEGHED
HHHHHHHHHHCCCCCCEECCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCC
PWLAPGDPTPIQTHMIFSNEPGVYRPGIDGYRTINTMIVTEDGVDIPSRFQANTPIDARV
CCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCEEE
IAL
EEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9733678; 11223522; 11210522 [H]