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The map label for this gene is pqqL [C]

Identifier: 89056536

GI number: 89056536

Start: 4147946

End: 4149337

Strand: Direct

Name: pqqL [C]

Synonym: Jann_4045

Alternate gene names: 89056536

Gene position: 4147946-4149337 (Clockwise)

Preceding gene: 89056535

Following gene: 89056537

Centisome position: 96.06

GC content: 63.15

Gene sequence:

>1392_bases
ATGATCCGCCCAATCCTCGCTTCAATGGGGCTTGCCGCCTTGGGCCTTACCGCCCTCCCCCTCCCGGCCAACGCTGCCGG
TGAAGTCACCGAATTCACCCTCGATAACGGCATGCAGGTCGTTGTGATCGAAGACCATCGCGGGGCCGCTGTTACACATA
TGGTGTGGTATCGCGCGGGTTCCGCCGATGAAATGCCAGGCCAGTCGGGCATTGCGCATTTCCTGGAACACCTGATGTTC
AAAGCGACCGATGATCTGGAAAGTCGGGAGTTTTCGCGCATCGTGGAAGAGAATGGCGGATCGGACAACGCCTTCACTTC
GTGGGATTACACTGCCTATCACCAACGCGTCTCCGCCGACCGTCTGGGCCTGATGATGATGATGGAAGCCGACCGGATGC
GCGATTTGGTCCTGGACGAGGACGAGGTGCGCACCGAGCGGCAGGTCATTCTGGAGGAGCGGGCGCAACGCACGGACACC
TCCCCCGGGGCGCTGTTCAATGAGCAGATGGCCGCCGCGATCCACCTCAACCATCCCTATGGTCGGCCAATCATCGGCTG
GCGGCACGAGATGGAGGAACTGAGCCTGCAAGACGCGCGCGATTGGTACGAGACCCACTACCACCCCAATAACGCGATCC
TGATCGTGGCCGGTGATGCCGATCCCGATGAGGTCCGCGCCCTGGCCGAGGAGCATTACGGGCCGATCCCGGCGAACCCG
GACATCGAGCCGATGGAAGCCCGCGACCGCCCGTCCGAGCCGCCCCATATTGCGGAGCGCCGGGTGATCTATGAAGATGC
CCGCGTCTCCAACCCTTACGTGTCGATCAACTTCCTCGCGCCCGAGCGGAACGCAGGCGATCAGGAGGAGGCCGCAGCGC
TGACGCTTCTGGCCGAGATCCTGGCAGGCTCCGGCTTCACCTCTGTGCTGCCGCGCGAGATGCAGATCGAGGACGAACGC
TCCCTGTTCGTCGGCGCGTATTACGGCGGCACCAGCCTGGATACGACAACCTTCACGCTGATCAACATGCCCCTGCCCGG
CACCCCGCTGGAAGAGGCCGAAGCCGAGATTCTGGCCGAGATTGACGAGTTTCTGGAAGAGGGCATCGACCCGGCTCAAT
TCGAGCGGATCCAGTTCCAGATCGACGCCGCCCGGATCTATGAGGAGGACGATGTGGAAGGTTTGGCCAGCGTCTATGGG
CGTGCCCTGACCTCCGGCCTGACGGTCGCCGATGTGCAGGCCTGGCCCGATATTCTCGCGGCGACCACCGTCGACGATGT
GATGGATGCCGCGCGCGACGTCTTCAGCCAGGGGGCCACGACGACGGGCTATCTGTTGAGACCCTCGGCCCCCGAAACCG
ACACTGAAACCGCTGGGGAGGTCTCCCAATGA

Upstream 100 bases:

>100_bases
CTTGCCGTCCGCGGCATAACGTATCCGTCAGCGCTGTTGATGCGGCGGGCAAACCCCATACATTGCGTCTCAACGATCAA
CCGCCCCGGAGATGCCATTC

Downstream 100 bases:

>100_bases
TCGCTCGTTTCCTGACGCCCTTCGTGGCCGCGCCCCTCTTGGCCGTGATGACCTTCACCGCGCCCTCACAGGCAGATATC
ATCGACATCCAGCCCGTCAC

Product: peptidase M16-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MIRPILASMGLAALGLTALPLPANAAGEVTEFTLDNGMQVVVIEDHRGAAVTHMVWYRAGSADEMPGQSGIAHFLEHLMF
KATDDLESREFSRIVEENGGSDNAFTSWDYTAYHQRVSADRLGLMMMMEADRMRDLVLDEDEVRTERQVILEERAQRTDT
SPGALFNEQMAAAIHLNHPYGRPIIGWRHEMEELSLQDARDWYETHYHPNNAILIVAGDADPDEVRALAEEHYGPIPANP
DIEPMEARDRPSEPPHIAERRVIYEDARVSNPYVSINFLAPERNAGDQEEAAALTLLAEILAGSGFTSVLPREMQIEDER
SLFVGAYYGGTSLDTTTFTLINMPLPGTPLEEAEAEILAEIDEFLEEGIDPAQFERIQFQIDAARIYEEDDVEGLASVYG
RALTSGLTVADVQAWPDILAATTVDDVMDAARDVFSQGATTTGYLLRPSAPETDTETAGEVSQ

Sequences:

>Translated_463_residues
MIRPILASMGLAALGLTALPLPANAAGEVTEFTLDNGMQVVVIEDHRGAAVTHMVWYRAGSADEMPGQSGIAHFLEHLMF
KATDDLESREFSRIVEENGGSDNAFTSWDYTAYHQRVSADRLGLMMMMEADRMRDLVLDEDEVRTERQVILEERAQRTDT
SPGALFNEQMAAAIHLNHPYGRPIIGWRHEMEELSLQDARDWYETHYHPNNAILIVAGDADPDEVRALAEEHYGPIPANP
DIEPMEARDRPSEPPHIAERRVIYEDARVSNPYVSINFLAPERNAGDQEEAAALTLLAEILAGSGFTSVLPREMQIEDER
SLFVGAYYGGTSLDTTTFTLINMPLPGTPLEEAEAEILAEIDEFLEEGIDPAQFERIQFQIDAARIYEEDDVEGLASVYG
RALTSGLTVADVQAWPDILAATTVDDVMDAARDVFSQGATTTGYLLRPSAPETDTETAGEVSQ
>Mature_463_residues
MIRPILASMGLAALGLTALPLPANAAGEVTEFTLDNGMQVVVIEDHRGAAVTHMVWYRAGSADEMPGQSGIAHFLEHLMF
KATDDLESREFSRIVEENGGSDNAFTSWDYTAYHQRVSADRLGLMMMMEADRMRDLVLDEDEVRTERQVILEERAQRTDT
SPGALFNEQMAAAIHLNHPYGRPIIGWRHEMEELSLQDARDWYETHYHPNNAILIVAGDADPDEVRALAEEHYGPIPANP
DIEPMEARDRPSEPPHIAERRVIYEDARVSNPYVSINFLAPERNAGDQEEAAALTLLAEILAGSGFTSVLPREMQIEDER
SLFVGAYYGGTSLDTTTFTLINMPLPGTPLEEAEAEILAEIDEFLEEGIDPAQFERIQFQIDAARIYEEDDVEGLASVYG
RALTSGLTVADVQAWPDILAATTVDDVMDAARDVFSQGATTTGYLLRPSAPETDTETAGEVSQ

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=238, Percent_Identity=30.2521008403361, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI46593007, Length=204, Percent_Identity=28.921568627451, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI155969707, Length=251, Percent_Identity=23.5059760956175, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1787770, Length=226, Percent_Identity=29.646017699115, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17553678, Length=275, Percent_Identity=28, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71999683, Length=204, Percent_Identity=27.4509803921569, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323192, Length=212, Percent_Identity=25, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357875, Length=228, Percent_Identity=30.2631578947368, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24646943, Length=228, Percent_Identity=30.2631578947368, Blast_Score=97, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 51170; Mature: 51170

Theoretical pI: Translated: 4.02; Mature: 4.02

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRPILASMGLAALGLTALPLPANAAGEVTEFTLDNGMQVVVIEDHRGAAVTHMVWYRAG
CCCHHHHHHHHHHHCCEECCCCCCCCCCEEEEEECCCCEEEEEECCCCCEEEEEEEEECC
SADEMPGQSGIAHFLEHLMFKATDDLESREFSRIVEENGGSDNAFTSWDYTAYHQRVSAD
CCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHH
RLGLMMMMEADRMRDLVLDEDEVRTERQVILEERAQRTDTSPGALFNEQMAAAIHLNHPY
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCEEEEEECCCC
GRPIIGWRHEMEELSLQDARDWYETHYHPNNAILIVAGDADPDEVRALAEEHYGPIPANP
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCC
DIEPMEARDRPSEPPHIAERRVIYEDARVSNPYVSINFLAPERNAGDQEEAAALTLLAEI
CCCCCCCCCCCCCCCCHHHHHEEECCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHH
LAGSGFTSVLPREMQIEDERSLFVGAYYGGTSLDTTTFTLINMPLPGTPLEEAEAEILAE
HHCCCHHHHCCCHHCCCCCCCEEEEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHH
IDEFLEEGIDPAQFERIQFQIDAARIYEEDDVEGLASVYGRALTSGLTVADVQAWPDILA
HHHHHHHCCCHHHEEEEEEEEEHHHHCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHH
ATTVDDVMDAARDVFSQGATTTGYLLRPSAPETDTETAGEVSQ
HHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIRPILASMGLAALGLTALPLPANAAGEVTEFTLDNGMQVVVIEDHRGAAVTHMVWYRAG
CCCHHHHHHHHHHHCCEECCCCCCCCCCEEEEEECCCCEEEEEECCCCCEEEEEEEEECC
SADEMPGQSGIAHFLEHLMFKATDDLESREFSRIVEENGGSDNAFTSWDYTAYHQRVSAD
CCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHH
RLGLMMMMEADRMRDLVLDEDEVRTERQVILEERAQRTDTSPGALFNEQMAAAIHLNHPY
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCEEEEEECCCC
GRPIIGWRHEMEELSLQDARDWYETHYHPNNAILIVAGDADPDEVRALAEEHYGPIPANP
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCC
DIEPMEARDRPSEPPHIAERRVIYEDARVSNPYVSINFLAPERNAGDQEEAAALTLLAEI
CCCCCCCCCCCCCCCCHHHHHEEECCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHH
LAGSGFTSVLPREMQIEDERSLFVGAYYGGTSLDTTTFTLINMPLPGTPLEEAEAEILAE
HHCCCHHHHCCCHHCCCCCCCEEEEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHH
IDEFLEEGIDPAQFERIQFQIDAARIYEEDDVEGLASVYGRALTSGLTVADVQAWPDILA
HHHHHHHCCCHHHEEEEEEEEEHHHHCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHH
ATTVDDVMDAARDVFSQGATTTGYLLRPSAPETDTETAGEVSQ
HHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]