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The map label for this gene is ahpC [C]

Identifier: 89056517

GI number: 89056517

Start: 4128969

End: 4129622

Strand: Direct

Name: ahpC [C]

Synonym: Jann_4026

Alternate gene names: 89056517

Gene position: 4128969-4129622 (Clockwise)

Preceding gene: 89056515

Following gene: 89056522

Centisome position: 95.62

GC content: 61.62

Gene sequence:

>654_bases
ATGGGCCTCCGCATCAACGACGACATTCCCAACATCACGGTCGAGACGGACCAGGGCACCACCAGCCTGCATGACTTTGT
GGGCGATCAATGGGCGATCCTGTTCTCGCACCCCAAGGACTTCACGCCCGTCTGCACCACCGAATTCGGCGCTGTGGCGC
AGCTGGCCGACGAATGGGCCGCGCGCAACACAAAGGTCATCGGCGTGTCCGTTGACGGCGTGGAGGAGCACAGGAAATGG
AAGGGCGACATCCAGTCCGTCGCATGCGCAGAGCCGACCTTCCCGATCATCGCCGACCCTGAGTTGGAGGTCTCCAAAGC
TTTCGACATGTTGCCTGCCGAGGCCTATCTGCCCGATGGTCGCACACCCAATGACACCGCCACCGTGCGGTCGGTCTTCA
TCATCGGACCGGACAAGAAGCTGAAGCTGACCATGACCTACCCGATGAATGTTGGTCGCAATTTTGCGGAGGTCCTGCGC
GCGTTGGACGGGTTGCAGACGGCCGCGAAAGAGAATGTCGCCACGCCAGCCAACTGGGTGCCCGGCCAGGATGTCGTGGT
TCCCGTGGCCGTGTCCGATGAGGATGCGATTGCGAAATACGGCGCCATCGACACCAAGCTGCCTTACCTGCGGATGGCGA
AATTGCCGGGCTGA

Upstream 100 bases:

>100_bases
TCGAAACACCTGTTCCTATTGCGGGGGCAAACCTTCAAACGGCGGAATATCTGGCCTATGTTCCGCCTGTAACGGCACAT
ATCAGGAAGGGAGATACCCA

Downstream 100 bases:

>100_bases
ACCGCTCGGGGCCCCCGCGTCACAACTTGGCCAAGATCCTTGGGCATACAGACCCCCAGCCCAGAACCGGCGGAGGTCGC
TGATGCCCAAGGACATCCTT

Product: 1-Cys peroxiredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MGLRINDDIPNITVETDQGTTSLHDFVGDQWAILFSHPKDFTPVCTTEFGAVAQLADEWAARNTKVIGVSVDGVEEHRKW
KGDIQSVACAEPTFPIIADPELEVSKAFDMLPAEAYLPDGRTPNDTATVRSVFIIGPDKKLKLTMTYPMNVGRNFAEVLR
ALDGLQTAAKENVATPANWVPGQDVVVPVAVSDEDAIAKYGAIDTKLPYLRMAKLPG

Sequences:

>Translated_217_residues
MGLRINDDIPNITVETDQGTTSLHDFVGDQWAILFSHPKDFTPVCTTEFGAVAQLADEWAARNTKVIGVSVDGVEEHRKW
KGDIQSVACAEPTFPIIADPELEVSKAFDMLPAEAYLPDGRTPNDTATVRSVFIIGPDKKLKLTMTYPMNVGRNFAEVLR
ALDGLQTAAKENVATPANWVPGQDVVVPVAVSDEDAIAKYGAIDTKLPYLRMAKLPG
>Mature_216_residues
GLRINDDIPNITVETDQGTTSLHDFVGDQWAILFSHPKDFTPVCTTEFGAVAQLADEWAARNTKVIGVSVDGVEEHRKWK
GDIQSVACAEPTFPIIADPELEVSKAFDMLPAEAYLPDGRTPNDTATVRSVFIIGPDKKLKLTMTYPMNVGRNFAEVLRA
LDGLQTAAKENVATPANWVPGQDVVVPVAVSDEDAIAKYGAIDTKLPYLRMAKLPG

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=226, Percent_Identity=45.1327433628319, Blast_Score=183, Evalue=1e-46,
Organism=Homo sapiens, GI4505591, Length=179, Percent_Identity=29.0502793296089, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI32455266, Length=179, Percent_Identity=29.0502793296089, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI32455264, Length=179, Percent_Identity=29.0502793296089, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI5453549, Length=167, Percent_Identity=29.940119760479, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI32189392, Length=179, Percent_Identity=27.3743016759777, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI32483377, Length=179, Percent_Identity=27.9329608938547, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI5802974, Length=179, Percent_Identity=27.9329608938547, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1786822, Length=160, Percent_Identity=26.25, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25153706, Length=208, Percent_Identity=40.3846153846154, Blast_Score=168, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI193204376, Length=180, Percent_Identity=30, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI32565831, Length=180, Percent_Identity=30, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17554494, Length=183, Percent_Identity=28.4153005464481, Blast_Score=74, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6319407, Length=215, Percent_Identity=48.8372093023256, Blast_Score=207, Evalue=8e-55,
Organism=Drosophila melanogaster, GI17975518, Length=198, Percent_Identity=42.9292929292929, Blast_Score=168, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24652434, Length=198, Percent_Identity=42.9292929292929, Blast_Score=167, Evalue=3e-42,
Organism=Drosophila melanogaster, GI24652436, Length=198, Percent_Identity=42.4242424242424, Blast_Score=167, Evalue=7e-42,
Organism=Drosophila melanogaster, GI24581278, Length=222, Percent_Identity=41.4414414414414, Blast_Score=160, Evalue=5e-40,
Organism=Drosophila melanogaster, GI17157991, Length=171, Percent_Identity=31.5789473684211, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641739, Length=171, Percent_Identity=31.5789473684211, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17738015, Length=182, Percent_Identity=29.1208791208791, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21357347, Length=198, Percent_Identity=25.7575757575758, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24656348, Length=168, Percent_Identity=29.1666666666667, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17864676, Length=168, Percent_Identity=29.1666666666667, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 23596; Mature: 23465

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLRINDDIPNITVETDQGTTSLHDFVGDQWAILFSHPKDFTPVCTTEFGAVAQLADEWA
CCCEECCCCCCEEEECCCCCHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
ARNTKVIGVSVDGVEEHRKWKGDIQSVACAEPTFPIIADPELEVSKAFDMLPAEAYLPDG
CCCCEEEEEEECCHHHHHHHHCCHHHEEECCCCCCEEECCCCHHHHHHHCCCCHHCCCCC
RTPNDTATVRSVFIIGPDKKLKLTMTYPMNVGRNFAEVLRALDGLQTAAKENVATPANWV
CCCCCCEEEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
PGQDVVVPVAVSDEDAIAKYGAIDTKLPYLRMAKLPG
CCCCEEEEEEECCCHHHHHHCCCCCCCCCEEECCCCC
>Mature Secondary Structure 
GLRINDDIPNITVETDQGTTSLHDFVGDQWAILFSHPKDFTPVCTTEFGAVAQLADEWA
CCEECCCCCCEEEECCCCCHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
ARNTKVIGVSVDGVEEHRKWKGDIQSVACAEPTFPIIADPELEVSKAFDMLPAEAYLPDG
CCCCEEEEEEECCHHHHHHHHCCHHHEEECCCCCCEEECCCCHHHHHHHCCCCHHCCCCC
RTPNDTATVRSVFIIGPDKKLKLTMTYPMNVGRNFAEVLRALDGLQTAAKENVATPANWV
CCCCCCEEEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
PGQDVVVPVAVSDEDAIAKYGAIDTKLPYLRMAKLPG
CCCCEEEEEEECCCHHHHHHCCCCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12125824 [H]