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The map label for this gene is dinB [H]

Identifier: 89056486

GI number: 89056486

Start: 4099107

End: 4100360

Strand: Direct

Name: dinB [H]

Synonym: Jann_3995

Alternate gene names: 89056486

Gene position: 4099107-4100360 (Clockwise)

Preceding gene: 89056484

Following gene: 89056488

Centisome position: 94.93

GC content: 64.99

Gene sequence:

>1254_bases
ATGTCCGCCCTGTGTCGAGATTGCCTGGAAACTTTTGACGACGCGCGTCGCTGCCCGGCGTGCCGGTCCCCGCGTGTGAC
GGCGCACCCCGAATTGTTTGACCTGTCCATCGCCCATATGGATTGCGACGCTTTCTACGCGTCGGTGGAAAAACGCGACA
ATCCGGAGCTGCACGACAAGCCCGTGATCATCGGTGGCGGCAGGCGGGGCGTGGTGTCGACCGCCTGCTACATCGCGCGG
ATCAAAGGCGTGCGGTCTGCCATGCCGATGTTCCAGGCCCTCAAGCTCTGCCCCGAAGCCGTCGTCGTGCGGGGCCGCAT
GGACACCTACGTCGAGGTCTCCAAACAGATCCGCCAGTTGATGGAAGAACTGACCCCCGCCATTGAGCCGCTGTCGCTGG
ACGAAGCGTTCATGGACCTCACCGGCACCGCGCGCGTCCACGGCAAGCCCCCCGCCGCGATGCTGGCAGGCCTGGTCAAA
CGGATGCGCGACGAGATCGGGATCACCGGCTCCATCGGCCTGTCGCACAACAAGTTTCTGGCCAAGATCGCCTCGGACCT
CGACAAGCCGCGCGGGTTTTCCGTCATCGGCGTGGCGGAGACGCAGGACTTCCTCAACGATAAGCCGGTGCGGATGATCT
GGGGGATTGGCGCTGTCGGGCAGGCCTCCCTCAACAAGGCCGGCATCCACACATTCAGTGACCTCCAACGCTGGGACAGG
CAGGCCCTGCATGAGCGGTTCGGGAGCATGGGCGAACGGCTCTGGCACCTTGCGCGGGGCGAAGACCACCGCGCCGTCAA
ACGCGACCGGGCGGTGAAAGGCGTCTCCAACGAGACAACGTTCCACGACGATATCGCAGATGTCGACCTGCTGGACGGCC
ACATCTGGCGCATGGCGGAAAAGGTCTCCGACCGGCTGAAAGCCAAGGGGATCGCCGGGCGGACTGTGACGCTGAAACTC
AAGCGTGCGGACTTCAAACTGATCACCCGGCGCAACACCCTGCCCGATGCGACGCAAACCGCCGACCGCATCTATGCCAC
CGCGCGGGCCCTCTTCGACCATATGACCCACCCTGAGCCCTACCGCCTTCTGGGCGTTGGCGTGGCCGACCTCATCTCCG
AGGATCAGGCCGACCGCGAAGGCAACCTGCTGGACCCGCAAGAGGCCGCCCGCCTGAAAGCCGAACGCGCCACCGATGCC
ATCCGCAATCGCTTCGGAGCCGATGCCATCCTGAAAGGCCGCGCGCTCCGCTGA

Upstream 100 bases:

>100_bases
CGGCATGGGACCCTGTCCTCACTCACCATCATGACCTCCCCTGTCAGGAGCGCGCCTCCGCTCCCTTTTGAACGCGCCCG
AATAGGCGTATCATCCCCCC

Downstream 100 bases:

>100_bases
CCGCTCCTCTTTCATCTGGGCCGGTACACCTCCGGGGGGTTTGCGCATCCCGGATGCGCATGGGGGGCTGGCCCCCACTC
TTAATAAAAACAATCCGCCC

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MSALCRDCLETFDDARRCPACRSPRVTAHPELFDLSIAHMDCDAFYASVEKRDNPELHDKPVIIGGGRRGVVSTACYIAR
IKGVRSAMPMFQALKLCPEAVVVRGRMDTYVEVSKQIRQLMEELTPAIEPLSLDEAFMDLTGTARVHGKPPAAMLAGLVK
RMRDEIGITGSIGLSHNKFLAKIASDLDKPRGFSVIGVAETQDFLNDKPVRMIWGIGAVGQASLNKAGIHTFSDLQRWDR
QALHERFGSMGERLWHLARGEDHRAVKRDRAVKGVSNETTFHDDIADVDLLDGHIWRMAEKVSDRLKAKGIAGRTVTLKL
KRADFKLITRRNTLPDATQTADRIYATARALFDHMTHPEPYRLLGVGVADLISEDQADREGNLLDPQEAARLKAERATDA
IRNRFGADAILKGRALR

Sequences:

>Translated_417_residues
MSALCRDCLETFDDARRCPACRSPRVTAHPELFDLSIAHMDCDAFYASVEKRDNPELHDKPVIIGGGRRGVVSTACYIAR
IKGVRSAMPMFQALKLCPEAVVVRGRMDTYVEVSKQIRQLMEELTPAIEPLSLDEAFMDLTGTARVHGKPPAAMLAGLVK
RMRDEIGITGSIGLSHNKFLAKIASDLDKPRGFSVIGVAETQDFLNDKPVRMIWGIGAVGQASLNKAGIHTFSDLQRWDR
QALHERFGSMGERLWHLARGEDHRAVKRDRAVKGVSNETTFHDDIADVDLLDGHIWRMAEKVSDRLKAKGIAGRTVTLKL
KRADFKLITRRNTLPDATQTADRIYATARALFDHMTHPEPYRLLGVGVADLISEDQADREGNLLDPQEAARLKAERATDA
IRNRFGADAILKGRALR
>Mature_416_residues
SALCRDCLETFDDARRCPACRSPRVTAHPELFDLSIAHMDCDAFYASVEKRDNPELHDKPVIIGGGRRGVVSTACYIARI
KGVRSAMPMFQALKLCPEAVVVRGRMDTYVEVSKQIRQLMEELTPAIEPLSLDEAFMDLTGTARVHGKPPAAMLAGLVKR
MRDEIGITGSIGLSHNKFLAKIASDLDKPRGFSVIGVAETQDFLNDKPVRMIWGIGAVGQASLNKAGIHTFSDLQRWDRQ
ALHERFGSMGERLWHLARGEDHRAVKRDRAVKGVSNETTFHDDIADVDLLDGHIWRMAEKVSDRLKAKGIAGRTVTLKLK
RADFKLITRRNTLPDATQTADRIYATARALFDHMTHPEPYRLLGVGVADLISEDQADREGNLLDPQEAARLKAERATDAI
RNRFGADAILKGRALR

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI154350220, Length=322, Percent_Identity=29.1925465838509, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI84043967, Length=338, Percent_Identity=25.4437869822485, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI7706681, Length=339, Percent_Identity=25.3687315634218, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI7705344, Length=106, Percent_Identity=46.2264150943396, Blast_Score=105, Evalue=7e-23,
Organism=Escherichia coli, GI1786425, Length=357, Percent_Identity=41.1764705882353, Blast_Score=221, Evalue=7e-59,
Organism=Escherichia coli, GI1787432, Length=367, Percent_Identity=26.158038147139, Blast_Score=93, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI193205700, Length=241, Percent_Identity=32.3651452282158, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI193205702, Length=241, Percent_Identity=32.3651452282158, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17537959, Length=189, Percent_Identity=24.3386243386243, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21355641, Length=269, Percent_Identity=29.7397769516729, Blast_Score=111, Evalue=9e-25,
Organism=Drosophila melanogaster, GI24644984, Length=269, Percent_Identity=29.7397769516729, Blast_Score=111, Evalue=9e-25,
Organism=Drosophila melanogaster, GI19923006, Length=345, Percent_Identity=24.3478260869565, Blast_Score=102, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 46367; Mature: 46236

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALCRDCLETFDDARRCPACRSPRVTAHPELFDLSIAHMDCDAFYASVEKRDNPELHDK
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHEEEEHHHHHHHHHHHHHCCCCCCCCCC
PVIIGGGRRGVVSTACYIARIKGVRSAMPMFQALKLCPEAVVVRGRMDTYVEVSKQIRQL
CEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHHH
MEELTPAIEPLSLDEAFMDLTGTARVHGKPPAAMLAGLVKRMRDEIGITGSIGLSHNKFL
HHHHHHHCCCCCHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHCCCCEECCCCHHHHH
AKIASDLDKPRGFSVIGVAETQDFLNDKPVRMIWGIGAVGQASLNKAGIHTFSDLQRWDR
HHHHHHCCCCCCCEEEEECHHHHHHCCCCEEEEECCCCCCHHHCCHHCCHHHHHHHHHHH
QALHERFGSMGERLWHLARGEDHRAVKRDRAVKGVSNETTFHDDIADVDLLDGHIWRMAE
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
KVSDRLKAKGIAGRTVTLKLKRADFKLITRRNTLPDATQTADRIYATARALFDHMTHPEP
HHHHHHHHCCCCCCEEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
YRLLGVGVADLISEDQADREGNLLDPQEAARLKAERATDAIRNRFGADAILKGRALR
HHEECCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCC
>Mature Secondary Structure 
SALCRDCLETFDDARRCPACRSPRVTAHPELFDLSIAHMDCDAFYASVEKRDNPELHDK
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHEEEEHHHHHHHHHHHHHCCCCCCCCCC
PVIIGGGRRGVVSTACYIARIKGVRSAMPMFQALKLCPEAVVVRGRMDTYVEVSKQIRQL
CEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHHH
MEELTPAIEPLSLDEAFMDLTGTARVHGKPPAAMLAGLVKRMRDEIGITGSIGLSHNKFL
HHHHHHHCCCCCHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHCCCCEECCCCHHHHH
AKIASDLDKPRGFSVIGVAETQDFLNDKPVRMIWGIGAVGQASLNKAGIHTFSDLQRWDR
HHHHHHCCCCCCCEEEEECHHHHHHCCCCEEEEECCCCCCHHHCCHHCCHHHHHHHHHHH
QALHERFGSMGERLWHLARGEDHRAVKRDRAVKGVSNETTFHDDIADVDLLDGHIWRMAE
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
KVSDRLKAKGIAGRTVTLKLKRADFKLITRRNTLPDATQTADRIYATARALFDHMTHPEP
HHHHHHHHCCCCCCEEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
YRLLGVGVADLISEDQADREGNLLDPQEAARLKAERATDAIRNRFGADAILKGRALR
HHEECCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]