Click here to switch to the map view.

The map label for this gene is hemZ [H]

Identifier: 89056350

GI number: 89056350

Start: 3955112

End: 3956440

Strand: Direct

Name: hemZ [H]

Synonym: Jann_3859

Alternate gene names: 89056350

Gene position: 3955112-3956440 (Clockwise)

Preceding gene: 89056340

Following gene: 89056356

Centisome position: 91.6

GC content: 64.48

Gene sequence:

>1329_bases
ATGGATCTCTATTCTCAACTGCGGCGTTTCGGCGTCCTCGATACCCATGTGCCCCGGTACACGTCCTACCCGCCCACGCC
GCATTTCACAGACACGGTCGGCGCGATGGATTATGGCCGTTGGCTGGCACGGATCCCGGAGGGGTCGGAGGTCTCTCTCT
ACATACATATTCCCTTCTGCCAGCGGCTTTGCTGGTTTTGTTCGGCGCGCACCCAGGGCGCGCCGGGCGGGGCGCCCGTG
GCCTCCTATGTCGATACTCTGATCCGCGAGGCCCGGGCCGTGGGGGCCGCTTTGCCACCCGGCGTGCGGGCGAGGAGTGT
CTATTGGGGCGGCGGAACGCCGACAATTCTGTCGCCTGCCGACATCACGCGCCTGTCGTGCGCCGTGCACAGCGCTATTC
CTTTGACCAATGACGCAGAGATTACGGTTGAGGTCGACCCGACCGAAATTGACGACGCGCGTATGGATGCACTGGCCCAG
ATGGGCATGACCCGCGCGTCCATCGGGGTGCAGGATTTCGACCCAGAGATCCAGAAAATCATCGGACGGGCACAAAGTTT
CGAGGCCACAAAGGCCGCCATCGACGGGCTCCGCGCCCGGGGCGTGGACGGCCTGACCATGGGCCTTCTCTACGGCTTGC
CAAAACAACGGCGCACCAGCCTGGCGCGTCTGACGCAGTTGCTTCTGACGCTGTCACCGGACCGCGTCACGGTGCAGCCC
TATGCCCATGTGCCCGCAATTGCGCGCCGACAAAGCCTGATCCCCACGGCGGATCTACCCACGCCCGAAGGCCAGTTGGC
GCTGTTCGATGCTGCCGCGGGGGTCCTGCGGTGGGATGGGTTTGACCCCATCGGCATTGACCATTTCGCTCTTCCCTCAG
ATGCGCTGTCGACGGCTTCAAGCCGGGGCGATCTGCGGCGCTGTTTTCAGGGCTACACCGACAACCCTGGCGGCGTGCTT
CTGGGCCTCGGGGCCTCGGCGGTGTCCCGGCTGCCACAGGGCTACGCCCAGAACGCGCCCGGCACCTCGGCTTACCTGAA
GGCCGTTGCGGCGGGGCGCTTCGCCACGGCACGCGGCCATCGTTTGAGCAAAGACGACGCTTTGCGCGGCCGTATGATCG
AGATGATCCTGTGCGATTTCCGGATCGACATCGCCAAATTGTTGGCCGAAAGGCTGGGACCGGTGGCGCGAATTGAGGAT
TTGCTGACCCATATGTTGCGCCAGTTCCCCGGTCAGATCGCACGTTTTGAGGGCGGCCTCAGGGTGCGGGCAAATTCCAA
GGCGATGGTCCGCGTGATCGCGCGCGCGCTGGACGCCTACGCACCTTAG

Upstream 100 bases:

>100_bases
GTCGATCATTCATGGCGTGGCTCCGAGCGTGTTGAACCACGGATGTCGCCGCTTGATCCAAATCAATGCGGGTCGTCCGG
TCGTCTGCGCAGGCTAGCAC

Downstream 100 bases:

>100_bases
GCGGCGCTGGCGTCTCCGAACGCCGCTTTCATCAGTTCGCGGGTGTAGGTCGTGCGGGGGTTGGCAAACAAATCCTCGGT
CCGGCCCGCCTCCACCACAT

Product: coproporphyrinogen III oxidase

Products: NA

Alternate protein names: Coprogen oxidase; Coproporphyrinogenase [H]

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MDLYSQLRRFGVLDTHVPRYTSYPPTPHFTDTVGAMDYGRWLARIPEGSEVSLYIHIPFCQRLCWFCSARTQGAPGGAPV
ASYVDTLIREARAVGAALPPGVRARSVYWGGGTPTILSPADITRLSCAVHSAIPLTNDAEITVEVDPTEIDDARMDALAQ
MGMTRASIGVQDFDPEIQKIIGRAQSFEATKAAIDGLRARGVDGLTMGLLYGLPKQRRTSLARLTQLLLTLSPDRVTVQP
YAHVPAIARRQSLIPTADLPTPEGQLALFDAAAGVLRWDGFDPIGIDHFALPSDALSTASSRGDLRRCFQGYTDNPGGVL
LGLGASAVSRLPQGYAQNAPGTSAYLKAVAAGRFATARGHRLSKDDALRGRMIEMILCDFRIDIAKLLAERLGPVARIED
LLTHMLRQFPGQIARFEGGLRVRANSKAMVRVIARALDAYAP

Sequences:

>Translated_442_residues
MDLYSQLRRFGVLDTHVPRYTSYPPTPHFTDTVGAMDYGRWLARIPEGSEVSLYIHIPFCQRLCWFCSARTQGAPGGAPV
ASYVDTLIREARAVGAALPPGVRARSVYWGGGTPTILSPADITRLSCAVHSAIPLTNDAEITVEVDPTEIDDARMDALAQ
MGMTRASIGVQDFDPEIQKIIGRAQSFEATKAAIDGLRARGVDGLTMGLLYGLPKQRRTSLARLTQLLLTLSPDRVTVQP
YAHVPAIARRQSLIPTADLPTPEGQLALFDAAAGVLRWDGFDPIGIDHFALPSDALSTASSRGDLRRCFQGYTDNPGGVL
LGLGASAVSRLPQGYAQNAPGTSAYLKAVAAGRFATARGHRLSKDDALRGRMIEMILCDFRIDIAKLLAERLGPVARIED
LLTHMLRQFPGQIARFEGGLRVRANSKAMVRVIARALDAYAP
>Mature_442_residues
MDLYSQLRRFGVLDTHVPRYTSYPPTPHFTDTVGAMDYGRWLARIPEGSEVSLYIHIPFCQRLCWFCSARTQGAPGGAPV
ASYVDTLIREARAVGAALPPGVRARSVYWGGGTPTILSPADITRLSCAVHSAIPLTNDAEITVEVDPTEIDDARMDALAQ
MGMTRASIGVQDFDPEIQKIIGRAQSFEATKAAIDGLRARGVDGLTMGLLYGLPKQRRTSLARLTQLLLTLSPDRVTVQP
YAHVPAIARRQSLIPTADLPTPEGQLALFDAAAGVLRWDGFDPIGIDHFALPSDALSTASSRGDLRRCFQGYTDNPGGVL
LGLGASAVSRLPQGYAQNAPGTSAYLKAVAAGRFATARGHRLSKDDALRGRMIEMILCDFRIDIAKLLAERLGPVARIED
LLTHMLRQFPGQIARFEGGLRVRANSKAMVRVIARALDAYAP

Specific function: Anaerobic transformation of coproporphyrinogen-III into protoporphyrinogen-IX. Dedicated to bacteriochlorophyll biosynthesis [H]

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=301, Percent_Identity=29.5681063122924, Blast_Score=96, Evalue=6e-20,
Organism=Escherichia coli, GI87082341, Length=435, Percent_Identity=36.551724137931, Blast_Score=275, Evalue=6e-75,
Organism=Escherichia coli, GI1789325, Length=195, Percent_Identity=32.3076923076923, Blast_Score=100, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004558
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: =1.3.99.22 [H]

Molecular weight: Translated: 47832; Mature: 47832

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLYSQLRRFGVLDTHVPRYTSYPPTPHFTDTVGAMDYGRWLARIPEGSEVSLYIHIPFC
CCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECHHH
QRLCWFCSARTQGAPGGAPVASYVDTLIREARAVGAALPPGVRARSVYWGGGTPTILSPA
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCEECCH
DITRLSCAVHSAIPLTNDAEITVEVDPTEIDDARMDALAQMGMTRASIGVQDFDPEIQKI
HHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCHHHHCCCCCCCHHHHHH
IGRAQSFEATKAAIDGLRARGVDGLTMGLLYGLPKQRRTSLARLTQLLLTLSPDRVTVQP
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEECC
YAHVPAIARRQSLIPTADLPTPEGQLALFDAAAGVLRWDGFDPIGIDHFALPSDALSTAS
CHHCCHHHHHHHCCCCCCCCCCCCCEEEEEHHCCHHEECCCCCCCCCCCCCCHHHHHHHH
SRGDLRRCFQGYTDNPGGVLLGLGASAVSRLPQGYAQNAPGTSAYLKAVAAGRFATARGH
CHHHHHHHHCCCCCCCCCEEEECCHHHHHHCCCCCCCCCCCHHHHHHHHHHCCHHHHCCC
RLSKDDALRGRMIEMILCDFRIDIAKLLAERLGPVARIEDLLTHMLRQFPGQIARFEGGL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHCCCE
RVRANSKAMVRVIARALDAYAP
EEEECCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDLYSQLRRFGVLDTHVPRYTSYPPTPHFTDTVGAMDYGRWLARIPEGSEVSLYIHIPFC
CCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECHHH
QRLCWFCSARTQGAPGGAPVASYVDTLIREARAVGAALPPGVRARSVYWGGGTPTILSPA
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCEECCH
DITRLSCAVHSAIPLTNDAEITVEVDPTEIDDARMDALAQMGMTRASIGVQDFDPEIQKI
HHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCHHHHCCCCCCCHHHHHH
IGRAQSFEATKAAIDGLRARGVDGLTMGLLYGLPKQRRTSLARLTQLLLTLSPDRVTVQP
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEECC
YAHVPAIARRQSLIPTADLPTPEGQLALFDAAAGVLRWDGFDPIGIDHFALPSDALSTAS
CHHCCHHHHHHHCCCCCCCCCCCCCEEEEEHHCCHHEECCCCCCCCCCCCCCHHHHHHHH
SRGDLRRCFQGYTDNPGGVLLGLGASAVSRLPQGYAQNAPGTSAYLKAVAAGRFATARGH
CHHHHHHHHCCCCCCCCCEEEECCHHHHHHCCCCCCCCCCCHHHHHHHHHHCCHHHHCCC
RLSKDDALRGRMIEMILCDFRIDIAKLLAERLGPVARIEDLLTHMLRQFPGQIARFEGGL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHCCCE
RVRANSKAMVRVIARALDAYAP
EEEECCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592416 [H]