Click here to switch to the map view.

The map label for this gene is kdgR [H]

Identifier: 89056330

GI number: 89056330

Start: 3934158

End: 3934952

Strand: Direct

Name: kdgR [H]

Synonym: Jann_3839

Alternate gene names: 89056330

Gene position: 3934158-3934952 (Clockwise)

Preceding gene: 89056320

Following gene: 89056331

Centisome position: 91.11

GC content: 63.14

Gene sequence:

>795_bases
GTGGTAGGCGAGGGTTCGGACAGCCAGGACGGGACGGTGGGCAAGGCGCTTTCGGTGCTGGACGCCGTGGCCGCTTTTGG
GCGGCCTGTGCGATTCGGTGAACTCCTGCAAGATAGCCCCTACCCCAAAGCGACGCTCTATCGCCTGGTCCAGGTTCTGA
CGAAGCAGTCGATGCTGGTCTATGAGCCCGACCGCCAGACCTATGCCCCCGGCCTGCGCCTTGTGCGGCTGGCCCATGCG
GCGTGGCAGACGACCTCACTCGCCCCCGTGGCCCGCCCATATCTGGAAGCGCTGTCGGCGGATATCGGAGAAACCATCCA
CCTTGCGCAGCTTGATGGCAGCAGCGTGCTGTATGTGGATAAAATCAACGCCCGCGACCCATTGCAGATGTATTCACAGG
CCGGAAAGGTCGCGCCGTGCTATTGCACCGGGGTGGGTAAGGCGATGATCGCGTTCCTGCCCGAAGACCAGCTTGAACCG
ATCCTGCGCCAGCAAAGCTATCACGTCTTCACCGCCCATACCTTTCCCGACGCCGCTGCCCTTCGCGAAGAGCTGCGCGC
CATCGTGGATCGTGGCCATGCCTACGACCGAGAAGAACACGAGCCGGGCATCATCTGCGTCGCGGTCCCAATTCTGACCC
GGTCCGGGCGGGTTCTGGGTGCGGTTTCTGTCACCTCTTCAACCGAGCGAACATCACTCACCGGGCTAGAGGCCCATCTG
CCCCGCCTTCACTCGGCGGTTTCATCCATTGCGGGGGAGGCCCAGGCTTGGCGCTTCCCCGATGCAGCAGAATAA

Upstream 100 bases:

>100_bases
TAGTCTTGTCAACAGCAAAGCGCGGGCGGATGCCGCAAAACGCGCCGGGCTGCAGGGTGATGTGGAGGACATCGCCCCGC
GTATTAAGGGAGCGACCAAC

Downstream 100 bases:

>100_bases
CCCAAGGGAGGACGCGGCGCATGTCGGGCCTGCAACTAACAGACGTCATCAAACGCTACGGCAAGACCCAGGTCATCCAT
GGGATCGACCTGACAATCGA

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MVGEGSDSQDGTVGKALSVLDAVAAFGRPVRFGELLQDSPYPKATLYRLVQVLTKQSMLVYEPDRQTYAPGLRLVRLAHA
AWQTTSLAPVARPYLEALSADIGETIHLAQLDGSSVLYVDKINARDPLQMYSQAGKVAPCYCTGVGKAMIAFLPEDQLEP
ILRQQSYHVFTAHTFPDAAALREELRAIVDRGHAYDREEHEPGIICVAVPILTRSGRVLGAVSVTSSTERTSLTGLEAHL
PRLHSAVSSIAGEAQAWRFPDAAE

Sequences:

>Translated_264_residues
MVGEGSDSQDGTVGKALSVLDAVAAFGRPVRFGELLQDSPYPKATLYRLVQVLTKQSMLVYEPDRQTYAPGLRLVRLAHA
AWQTTSLAPVARPYLEALSADIGETIHLAQLDGSSVLYVDKINARDPLQMYSQAGKVAPCYCTGVGKAMIAFLPEDQLEP
ILRQQSYHVFTAHTFPDAAALREELRAIVDRGHAYDREEHEPGIICVAVPILTRSGRVLGAVSVTSSTERTSLTGLEAHL
PRLHSAVSSIAGEAQAWRFPDAAE
>Mature_264_residues
MVGEGSDSQDGTVGKALSVLDAVAAFGRPVRFGELLQDSPYPKATLYRLVQVLTKQSMLVYEPDRQTYAPGLRLVRLAHA
AWQTTSLAPVARPYLEALSADIGETIHLAQLDGSSVLYVDKINARDPLQMYSQAGKVAPCYCTGVGKAMIAFLPEDQLEP
ILRQQSYHVFTAHTFPDAAALREELRAIVDRGHAYDREEHEPGIICVAVPILTRSGRVLGAVSVTSSTERTSLTGLEAHL
PRLHSAVSSIAGEAQAWRFPDAAE

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=256, Percent_Identity=31.640625, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1786468, Length=219, Percent_Identity=31.0502283105023, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI87082359, Length=226, Percent_Identity=26.1061946902655, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1789999, Length=242, Percent_Identity=26.4462809917355, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1790752, Length=252, Percent_Identity=26.984126984127, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788581, Length=213, Percent_Identity=27.6995305164319, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1786715, Length=218, Percent_Identity=23.8532110091743, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28637; Mature: 28637

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGEGSDSQDGTVGKALSVLDAVAAFGRPVRFGELLQDSPYPKATLYRLVQVLTKQSMLV
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCEEE
YEPDRQTYAPGLRLVRLAHAAWQTTSLAPVARPYLEALSADIGETIHLAQLDGSSVLYVD
ECCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCEEEEEE
KINARDPLQMYSQAGKVAPCYCTGVGKAMIAFLPEDQLEPILRQQSYHVFTAHTFPDAAA
CCCCCCHHHHHHHCCCCCCEEECHHHHHHHHHCCCHHHHHHHHCCCCEEEEECCCCCHHH
LREELRAIVDRGHAYDREEHEPGIICVAVPILTRSGRVLGAVSVTSSTERTSLTGLEAHL
HHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHH
PRLHSAVSSIAGEAQAWRFPDAAE
HHHHHHHHHHHCCHHHCCCCCCCC
>Mature Secondary Structure
MVGEGSDSQDGTVGKALSVLDAVAAFGRPVRFGELLQDSPYPKATLYRLVQVLTKQSMLV
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCEEE
YEPDRQTYAPGLRLVRLAHAAWQTTSLAPVARPYLEALSADIGETIHLAQLDGSSVLYVD
ECCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCEEEEEE
KINARDPLQMYSQAGKVAPCYCTGVGKAMIAFLPEDQLEPILRQQSYHVFTAHTFPDAAA
CCCCCCHHHHHHHCCCCCCEEECHHHHHHHHHCCCHHHHHHHHCCCCEEEEECCCCCHHH
LREELRAIVDRGHAYDREEHEPGIICVAVPILTRSGRVLGAVSVTSSTERTSLTGLEAHL
HHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHH
PRLHSAVSSIAGEAQAWRFPDAAE
HHHHHHHHHHHCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]