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The map label for this gene is ifcA [H]

Identifier: 89056259

GI number: 89056259

Start: 3850741

End: 3852123

Strand: Direct

Name: ifcA [H]

Synonym: Jann_3768

Alternate gene names: 89056259

Gene position: 3850741-3852123 (Clockwise)

Preceding gene: 89056258

Following gene: 89056266

Centisome position: 89.18

GC content: 65.51

Gene sequence:

>1383_bases
ATGTCGGTGCGGACCACACCGGATGCCGGGTTTGATCTGCACGTCCCTGTGCTGGTGATCGGTGCCGGGGCCTGCGGGCT
GGTGGCAGCACTTTCGGTGCAGGAAGGCGGCGGGGACGTACTGGTGATCGAAGCGGATGCGGCACCTTCCGGCTCGACCG
CGCTGTCGGCGGGACTGATCCCCGCGGCGGGCACGACGTTCCAGACCAAAGCTGGAATTCACGATGACGCGGAGCGTTTC
GCCGATGACATCCAGCGCAAGGCAAAGGGTGACAACCCTCAGGCGCTTGTGGATTTGCTGTCGCGGCAGGCCGGTCCCAC
CATTGAATGGCTCTCTGACAGATACGGTCTGCCGTTCTCGGTCGTGTCCGATTTCGACTATCCCGGCCATTCCTGCCGCC
GGATGCATGGCTTGCCCACGCGCTCGGGGCGGGAGTTGGTCGACCGGTTGCGCGCGACTTGTGAGGCGGAGGGGATCGAC
ATTGTCTGCAACCGGCGCGCGACGACCCTGTTCATCGACAATGATCGGATCACCGGTATCGAGGTCCAGGGACCCGACGG
ACCCGAGCGGATCGGCTGCGACGCGCTGGTGCTGGCCTGCAACGGGTTTGGTGGCAACCGCGAGATGGTGACGCGGTTCA
TGCCAGAGATCGAGGACGCCGTGTGGTTCGGCCATGACGGCAATCGTGGCGACGCCATCCGCTGGGGGGAGGCGCTTGGC
GCAGGTCTTATGCATCTTGGGGCGTATCAGGGGCACGGCAACGTCGCCCACCCCCAAGGCATCCTGATCACATGGGCCGT
TATCACCGAGGGCGGCGTGCAGGTGAACGCGGCGGGGGAGCGGTTCTGGGATGAAAGCCAGGGCTATTCCGAAGCTGGTC
GCGCGGTCCTGGCCCAACCCGGCGGGATTGCGTGGGCAATCTTCGATACGCGCATCGCAGGCGTGGCGCGCCAGTTTCAG
GATTTCAAGGATGCGGAAGCGCTTGGCGCCATTCGCACTGCCGATACGATCAAGGGATTGGCAGACGCGACAGGCCTTCC
CGAAGCGGCCCTGCGGTCAACGCTTGACGGCATCCCGTCGTCCGGCACCGATGCGTTCGGGCGGATGTTTCATGGCAAGC
CCCTCATCCCGCCCTATTGCGCGGTCAAGGTGACTGGCGCGCTGTTTCATACCCAGGGCGGGCTCGACATCGACGAAGAT
GCCCGGGTGCGGCGGGCGGATGGCACCAGCTTTCCAAACATCTTTGCCGCCGGGGGGGCGGCCGTCGGCGTCTCGGGAAA
AGGCGACAGCGGGTATCTGTCGGGCAATGGCCTGTTGGCGGCGGTGGTCTTGGGCCATGTCGCCGGACGCCGTGCGGCCA
TGGACACAAGGACCGAGCCCTGA

Upstream 100 bases:

>100_bases
CCGACCGGATGTTCGATTTCGACGGCCTCAACGAGCGGATCGGGACGTCCGAGATGCTGATCAAGGGAAAGCGGTTCGAA
GACAGCGGCAGATCCTGACG

Downstream 100 bases:

>100_bases
ACTCTACGCGTCCGCAGGATCAGGCGTGCCCGGTGACCTGATGTGCGATCTGCCGCGCCTCGTCCGTCATCACGCGATCT
CCACGCCAAGCCACATGCCC

Product: fumarate reductase/succinate dehydrogenase flavoprotein-like protein

Products: NA

Alternate protein names: Fe(3+)-induced flavocytochrome C3; Ifc3; Iron(III)-induced flavocytochrome C3 [H]

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MSVRTTPDAGFDLHVPVLVIGAGACGLVAALSVQEGGGDVLVIEADAAPSGSTALSAGLIPAAGTTFQTKAGIHDDAERF
ADDIQRKAKGDNPQALVDLLSRQAGPTIEWLSDRYGLPFSVVSDFDYPGHSCRRMHGLPTRSGRELVDRLRATCEAEGID
IVCNRRATTLFIDNDRITGIEVQGPDGPERIGCDALVLACNGFGGNREMVTRFMPEIEDAVWFGHDGNRGDAIRWGEALG
AGLMHLGAYQGHGNVAHPQGILITWAVITEGGVQVNAAGERFWDESQGYSEAGRAVLAQPGGIAWAIFDTRIAGVARQFQ
DFKDAEALGAIRTADTIKGLADATGLPEAALRSTLDGIPSSGTDAFGRMFHGKPLIPPYCAVKVTGALFHTQGGLDIDED
ARVRRADGTSFPNIFAAGGAAVGVSGKGDSGYLSGNGLLAAVVLGHVAGRRAAMDTRTEP

Sequences:

>Translated_460_residues
MSVRTTPDAGFDLHVPVLVIGAGACGLVAALSVQEGGGDVLVIEADAAPSGSTALSAGLIPAAGTTFQTKAGIHDDAERF
ADDIQRKAKGDNPQALVDLLSRQAGPTIEWLSDRYGLPFSVVSDFDYPGHSCRRMHGLPTRSGRELVDRLRATCEAEGID
IVCNRRATTLFIDNDRITGIEVQGPDGPERIGCDALVLACNGFGGNREMVTRFMPEIEDAVWFGHDGNRGDAIRWGEALG
AGLMHLGAYQGHGNVAHPQGILITWAVITEGGVQVNAAGERFWDESQGYSEAGRAVLAQPGGIAWAIFDTRIAGVARQFQ
DFKDAEALGAIRTADTIKGLADATGLPEAALRSTLDGIPSSGTDAFGRMFHGKPLIPPYCAVKVTGALFHTQGGLDIDED
ARVRRADGTSFPNIFAAGGAAVGVSGKGDSGYLSGNGLLAAVVLGHVAGRRAAMDTRTEP
>Mature_459_residues
SVRTTPDAGFDLHVPVLVIGAGACGLVAALSVQEGGGDVLVIEADAAPSGSTALSAGLIPAAGTTFQTKAGIHDDAERFA
DDIQRKAKGDNPQALVDLLSRQAGPTIEWLSDRYGLPFSVVSDFDYPGHSCRRMHGLPTRSGRELVDRLRATCEAEGIDI
VCNRRATTLFIDNDRITGIEVQGPDGPERIGCDALVLACNGFGGNREMVTRFMPEIEDAVWFGHDGNRGDAIRWGEALGA
GLMHLGAYQGHGNVAHPQGILITWAVITEGGVQVNAAGERFWDESQGYSEAGRAVLAQPGGIAWAIFDTRIAGVARQFQD
FKDAEALGAIRTADTIKGLADATGLPEAALRSTLDGIPSSGTDAFGRMFHGKPLIPPYCAVKVTGALFHTQGGLDIDEDA
RVRRADGTSFPNIFAAGGAAVGVSGKGDSGYLSGNGLLAAVVLGHVAGRRAAMDTRTEP

Specific function: Catalyzes unidirectional fumarate reduction using artificial electron donors such as methyl viologen. The physiological reductant is unknown [H]

COG id: COG1053

COG function: function code C; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI71986328, Length=480, Percent_Identity=28.5416666666667, Blast_Score=132, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6320788, Length=481, Percent_Identity=25.1559251559252, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6322511, Length=484, Percent_Identity=23.9669421487603, Blast_Score=87, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003953
- InterPro:   IPR013027
- InterPro:   IPR010960
- InterPro:   IPR011031 [H]

Pfam domain/function: PF00890 FAD_binding_2 [H]

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 48098; Mature: 47967

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVRTTPDAGFDLHVPVLVIGAGACGLVAALSVQEGGGDVLVIEADAAPSGSTALSAGLI
CCCCCCCCCCCEEECCEEEEECCHHHHHEEEEEECCCCCEEEEECCCCCCCCCHHHCCCC
PAAGTTFQTKAGIHDDAERFADDIQRKAKGDNPQALVDLLSRQAGPTIEWLSDRYGLPFS
CCCCCCEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHCCCCCCC
VVSDFDYPGHSCRRMHGLPTRSGRELVDRLRATCEAEGIDIVCNRRATTLFIDNDRITGI
EECCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCEEEEEEECCCEEEE
EVQGPDGPERIGCDALVLACNGFGGNREMVTRFMPEIEDAVWFGHDGNRGDAIRWGEALG
EEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHH
AGLMHLGAYQGHGNVAHPQGILITWAVITEGGVQVNAAGERFWDESQGYSEAGRAVLAQP
HHHHHHCEECCCCCCCCCCCEEEEEEEEECCCEEEECCCHHHCCCCCCHHHHCCEEEECC
GGIAWAIFDTRIAGVARQFQDFKDAEALGAIRTADTIKGLADATGLPEAALRSTLDGIPS
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
SGTDAFGRMFHGKPLIPPYCAVKVTGALFHTQGGLDIDEDARVRRADGTSFPNIFAAGGA
CCCHHHHHHHCCCCCCCCHHHEEEEEEEEECCCCCCCCCCCCEEECCCCCCCCEEECCCE
AVGVSGKGDSGYLSGNGLLAAVVLGHVAGRRAAMDTRTEP
EEECCCCCCCCEECCCCHHHHHHHHHHHCCHHHCCCCCCC
>Mature Secondary Structure 
SVRTTPDAGFDLHVPVLVIGAGACGLVAALSVQEGGGDVLVIEADAAPSGSTALSAGLI
CCCCCCCCCCEEECCEEEEECCHHHHHEEEEEECCCCCEEEEECCCCCCCCCHHHCCCC
PAAGTTFQTKAGIHDDAERFADDIQRKAKGDNPQALVDLLSRQAGPTIEWLSDRYGLPFS
CCCCCCEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHCCCCCCC
VVSDFDYPGHSCRRMHGLPTRSGRELVDRLRATCEAEGIDIVCNRRATTLFIDNDRITGI
EECCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCEEEEEEECCCEEEE
EVQGPDGPERIGCDALVLACNGFGGNREMVTRFMPEIEDAVWFGHDGNRGDAIRWGEALG
EEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHH
AGLMHLGAYQGHGNVAHPQGILITWAVITEGGVQVNAAGERFWDESQGYSEAGRAVLAQP
HHHHHHCEECCCCCCCCCCCEEEEEEEEECCCEEEECCCHHHCCCCCCHHHHCCEEEECC
GGIAWAIFDTRIAGVARQFQDFKDAEALGAIRTADTIKGLADATGLPEAALRSTLDGIPS
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
SGTDAFGRMFHGKPLIPPYCAVKVTGALFHTQGGLDIDEDARVRRADGTSFPNIFAAGGA
CCCHHHHHHHCCCCCCCCHHHEEEEEEEEECCCCCCCCCCCCEEECCCCCCCCEEECCCE
AVGVSGKGDSGYLSGNGLLAAVVLGHVAGRRAAMDTRTEP
EEECCCCCCCCEECCCCHHHHHHHHHHHCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10455032; 10581549 [H]