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The map label for this gene is yybE [H]

Identifier: 89056247

GI number: 89056247

Start: 3837550

End: 3838455

Strand: Direct

Name: yybE [H]

Synonym: Jann_3756

Alternate gene names: 89056247

Gene position: 3837550-3838455 (Clockwise)

Preceding gene: 89056235

Following gene: 89056254

Centisome position: 88.87

GC content: 56.51

Gene sequence:

>906_bases
ATGCACGACAAGTTTCTGAATTACTTCGACGAAACCGCCCGGCAGGGATCTATTCGCAAAGCCGCGGCGGTGCTGAACAT
GTCGTCGTCCTCGCTCAATCGGAAGATCATCAGCACAGAAAATAGGCTGGGGATCCGCCTATTTGATCGTCATGCGGACG
GGGTCACGTTGACCGAAGCGGGTGTTGTGGTGCTGGAGCATTGCCGAAACACGCTCTTTGACTATCAACGAATCGTAAAC
ATGGTGGAAGACATCCGCGATATGCGGACCGGCCATATTGATATCCTGACACTCGACTCCATAGCCCTCAGCGTGCTGCC
GGAAGTGCTAGACGATTTTCAGGATGCCTACCCCCAGGTCGCCTACACGATCCAAACGGATGAGCCGCATGCCGTGATGC
AGGCGGTCGCGAATGGAACGGCTGATATCGGGTTGTCGTTCAGCAATGATCTGCACCCCGACGTGCGCTGTCAGGCGGAA
AAATCCACGCCCATCGGGGCGATCATGGCCCATGACCATCCGCTCGCTGAGCGTGACCTGATCGAGGTTGGCGATCTTGC
GCCGTACCAGCTGATCCGGTCCTACGATAGCCAGACACACCGGTCCTTCGTGAACGAAGCGGTGTCGTCTCTTGGCGTGC
AGCTTTCGACACAGATGGTCACAAACTCCTTGCCGTTGGCGAAGACCATGATCTTGAATGGGCGCGGCGTCGGTATCTAT
TCCAAGATCGGTTTTATTGAAGAAATCGAGGATGGGCGATTGCGATATGTCGCCATCAACTCGCCGCTCCTGCGCGAGCT
TAGGATTGGCGTGCTCATCTCAGCAAGGACCGGGTTGTTGCCGGTCCAGCATCTCCTTGCGCGCGCCCTGTCGAAATCGC
TCCGGTCTTTGCGTCTGGACAGCTAA

Upstream 100 bases:

>100_bases
CTAGACGCAGGGAGGGCGATGCATATAGGGTCAAAATCCGCGAAAGATGCTGCCTTTTTTGCAGCGCTCAGTCTAAGTGG
CGCACGAGGGAACCGCACCG

Downstream 100 bases:

>100_bases
GATCTTTTCGCAAGTCGCCACATTGTCAGTCTAGATGGATTTTTTCCCACCCTGTTACGGCGAAAACAGCAACTGAACGG
TCTGGATTCATGGGCATGGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MHDKFLNYFDETARQGSIRKAAAVLNMSSSSLNRKIISTENRLGIRLFDRHADGVTLTEAGVVVLEHCRNTLFDYQRIVN
MVEDIRDMRTGHIDILTLDSIALSVLPEVLDDFQDAYPQVAYTIQTDEPHAVMQAVANGTADIGLSFSNDLHPDVRCQAE
KSTPIGAIMAHDHPLAERDLIEVGDLAPYQLIRSYDSQTHRSFVNEAVSSLGVQLSTQMVTNSLPLAKTMILNGRGVGIY
SKIGFIEEIEDGRLRYVAINSPLLRELRIGVLISARTGLLPVQHLLARALSKSLRSLRLDS

Sequences:

>Translated_301_residues
MHDKFLNYFDETARQGSIRKAAAVLNMSSSSLNRKIISTENRLGIRLFDRHADGVTLTEAGVVVLEHCRNTLFDYQRIVN
MVEDIRDMRTGHIDILTLDSIALSVLPEVLDDFQDAYPQVAYTIQTDEPHAVMQAVANGTADIGLSFSNDLHPDVRCQAE
KSTPIGAIMAHDHPLAERDLIEVGDLAPYQLIRSYDSQTHRSFVNEAVSSLGVQLSTQMVTNSLPLAKTMILNGRGVGIY
SKIGFIEEIEDGRLRYVAINSPLLRELRIGVLISARTGLLPVQHLLARALSKSLRSLRLDS
>Mature_301_residues
MHDKFLNYFDETARQGSIRKAAAVLNMSSSSLNRKIISTENRLGIRLFDRHADGVTLTEAGVVVLEHCRNTLFDYQRIVN
MVEDIRDMRTGHIDILTLDSIALSVLPEVLDDFQDAYPQVAYTIQTDEPHAVMQAVANGTADIGLSFSNDLHPDVRCQAE
KSTPIGAIMAHDHPLAERDLIEVGDLAPYQLIRSYDSQTHRSFVNEAVSSLGVQLSTQMVTNSLPLAKTMILNGRGVGIY
SKIGFIEEIEDGRLRYVAINSPLLRELRIGVLISARTGLLPVQHLLARALSKSLRSLRLDS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=200, Percent_Identity=27.5, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI157672245, Length=192, Percent_Identity=23.9583333333333, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787601, Length=138, Percent_Identity=35.5072463768116, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788296, Length=248, Percent_Identity=26.2096774193548, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789204, Length=251, Percent_Identity=21.5139442231076, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790399, Length=265, Percent_Identity=20.7547169811321, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787530, Length=230, Percent_Identity=24.3478260869565, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788748, Length=218, Percent_Identity=22.9357798165138, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787879, Length=265, Percent_Identity=24.1509433962264, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI2367136, Length=142, Percent_Identity=29.5774647887324, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787128, Length=260, Percent_Identity=26.5384615384615, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33406; Mature: 33406

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDKFLNYFDETARQGSIRKAAAVLNMSSSSLNRKIISTENRLGIRLFDRHADGVTLTEA
CCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHCCHHCCCCCCCEEEEEECCCCCEEEHHH
GVVVLEHCRNTLFDYQRIVNMVEDIRDMRTGHIDILTLDSIALSVLPEVLDDFQDAYPQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCE
AYTIQTDEPHAVMQAVANGTADIGLSFSNDLHPDVRCQAEKSTPIGAIMAHDHPLAERDL
EEEEECCCHHHHHHHHHCCCCCEEEECCCCCCCCCEEECCCCCCCEEEEECCCCCCHHHH
IEVGDLAPYQLIRSYDSQTHRSFVNEAVSSLGVQLSTQMVTNSLPLAKTMILNGRGVGIY
HHHCCCCHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHEEECCCCCCHH
SKIGFIEEIEDGRLRYVAINSPLLRELRIGVLISARTGLLPVQHLLARALSKSLRSLRLD
HHHCHHHHHCCCCEEEEEECCHHHHHHHHCEEEECCCCCHHHHHHHHHHHHHHHHHHCCC
S
C
>Mature Secondary Structure
MHDKFLNYFDETARQGSIRKAAAVLNMSSSSLNRKIISTENRLGIRLFDRHADGVTLTEA
CCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHCCHHCCCCCCCEEEEEECCCCCEEEHHH
GVVVLEHCRNTLFDYQRIVNMVEDIRDMRTGHIDILTLDSIALSVLPEVLDDFQDAYPQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCE
AYTIQTDEPHAVMQAVANGTADIGLSFSNDLHPDVRCQAEKSTPIGAIMAHDHPLAERDL
EEEEECCCHHHHHHHHHCCCCCEEEECCCCCCCCCEEECCCCCCCEEEEECCCCCCHHHH
IEVGDLAPYQLIRSYDSQTHRSFVNEAVSSLGVQLSTQMVTNSLPLAKTMILNGRGVGIY
HHHCCCCHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHEEECCCCCCHH
SKIGFIEEIEDGRLRYVAINSPLLRELRIGVLISARTGLLPVQHLLARALSKSLRSLRLD
HHHCHHHHHCCCCEEEEEECCHHHHHHHHCEEEECCCCCHHHHHHHHHHHHHHHHHHCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]