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The map label for this gene is ygjG [C]

Identifier: 89056003

GI number: 89056003

Start: 3567911

End: 3569254

Strand: Direct

Name: ygjG [C]

Synonym: Jann_3512

Alternate gene names: 89056003

Gene position: 3567911-3569254 (Clockwise)

Preceding gene: 89056002

Following gene: 89056004

Centisome position: 82.63

GC content: 62.65

Gene sequence:

>1344_bases
ATGAAAGACTCCAACTTCCTGAAGGAAAACAACGGGCGTCTGATGTGGCACCCGATGACCTCCCCCAAAGACAGCATCGA
CACGCCGCCCAAGATCGTGACCGAAGGCCATGGTGTGCGGATCAAGGACATCGACGGGCATGAGGTCGTGGATGCTGTGG
GCGGCTTGTGGAACGTGAACCTCGGGTACTCCTGCCAACCGGTGAAAGACGCGATCTCGGCGCAATTGGACCGCTTGCCG
TATTACTCGACGTTCCGGGGCACCTCCAACGATGCCGCGATTGAACTGTCCTATGAGCTGTCACAATTCTTCGCCCCCGA
TGGGCTGTCGCGCGCGTTTTTCACATCCGGCGGATCCGATAGCGTGGAGACCTCCCTGCGGCTGGCGCGGCAGTACCACA
AACTGCGCGGAGAGCCGGGGCGCGTGAAGTTTCTGTCGCTCAAGAAAGGCTATCACGGAACCCATATGGGCGGCGCGTCG
GTCAACGGGAACGCCAATTTTCGCACGGCTTATGAACCGCTTTTGCCCGGCTGCTACCACATCCCGGCGCCCTACACCTA
CCGCAACCCGTTCAATGAGACGGACCCTGAGCGTCTGGCACAGCTGTGCGCGCAAGCGCTGGAGGACGAGATCGCGTTTC
AGGGGGCCAGCACGATTGCCGCCATGATCATGGAGCCGATCCTGGGTGCGGGCGGCGTGATCCCGCCGCACAAGTCCTTT
GCCCCGATGGTGGCCGAGATTTGCGCGCGCAGCGGCATCCTTCTGATCACCGATGAGGTCATCACAGCCTACGGGCGCAC
GGGCGCCTGGACGGGCGCGCGGCTGTGGGGCATCCAGCCCGATATGATGGCGACGGCCAAGGCGATCACCAACGGCTACT
TCCCCTTCGGCGCGGTGATGCTTGGTGACAGGATGGTGGAGACATTTGAAAACAACGCCAGCGCCAAGATTGGCCATGGC
TACACCTACTCAGGCCACCCCGTGGGCGCGGCAGCGGCGCTGGCGTGTTTGGCGGAAACGCAGCGATTGAACGTGACCGA
GAACGCCACCGCGCGTGGCACGCAGCTTTATGAAGGCTGTCTTGCCCTGCAGGAAAAATACGACGTGATCGGTGATGTGC
GCGGCGGGCACGGCCTGATGACCGCGATCGAGATGGTGAGTGACCGGGAGACCAAAGCGCCCGATGCAGCCTCTGGCGGA
GCGGTGCAGGAGGTCGCGTACCAGAACGGTGCGATGGTGCGCGTCTCTGGCCCCAACCTGATCCTGTCACCGCCGCTGAT
CCTGACGGAAGACGACGCCGCAACCATCCTGAGCGCGCTCGACAAGGGCTTCGCATCCCTGTGA

Upstream 100 bases:

>100_bases
TCACCCGAAATTGGGGCGGCACCCTGCCCCGCAGTGTGGAAGCCGCCTGGGCCCGCACGCTGACTGACACACTGGACCCC
TCTTCTATGGACATCGCCTC

Downstream 100 bases:

>100_bases
GCAACGAGCTCCGTGATTACGTCGTGCTTTTGGGCACCAAGGGCGGGCCTTCACAGCGCCCCGGCTCCTCCAAGCCAACA
TCCAACCTTTATGTGTTGAA

Product: hypothetical protein

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MKDSNFLKENNGRLMWHPMTSPKDSIDTPPKIVTEGHGVRIKDIDGHEVVDAVGGLWNVNLGYSCQPVKDAISAQLDRLP
YYSTFRGTSNDAAIELSYELSQFFAPDGLSRAFFTSGGSDSVETSLRLARQYHKLRGEPGRVKFLSLKKGYHGTHMGGAS
VNGNANFRTAYEPLLPGCYHIPAPYTYRNPFNETDPERLAQLCAQALEDEIAFQGASTIAAMIMEPILGAGGVIPPHKSF
APMVAEICARSGILLITDEVITAYGRTGAWTGARLWGIQPDMMATAKAITNGYFPFGAVMLGDRMVETFENNASAKIGHG
YTYSGHPVGAAAALACLAETQRLNVTENATARGTQLYEGCLALQEKYDVIGDVRGGHGLMTAIEMVSDRETKAPDAASGG
AVQEVAYQNGAMVRVSGPNLILSPPLILTEDDAATILSALDKGFASL

Sequences:

>Translated_447_residues
MKDSNFLKENNGRLMWHPMTSPKDSIDTPPKIVTEGHGVRIKDIDGHEVVDAVGGLWNVNLGYSCQPVKDAISAQLDRLP
YYSTFRGTSNDAAIELSYELSQFFAPDGLSRAFFTSGGSDSVETSLRLARQYHKLRGEPGRVKFLSLKKGYHGTHMGGAS
VNGNANFRTAYEPLLPGCYHIPAPYTYRNPFNETDPERLAQLCAQALEDEIAFQGASTIAAMIMEPILGAGGVIPPHKSF
APMVAEICARSGILLITDEVITAYGRTGAWTGARLWGIQPDMMATAKAITNGYFPFGAVMLGDRMVETFENNASAKIGHG
YTYSGHPVGAAAALACLAETQRLNVTENATARGTQLYEGCLALQEKYDVIGDVRGGHGLMTAIEMVSDRETKAPDAASGG
AVQEVAYQNGAMVRVSGPNLILSPPLILTEDDAATILSALDKGFASL
>Mature_447_residues
MKDSNFLKENNGRLMWHPMTSPKDSIDTPPKIVTEGHGVRIKDIDGHEVVDAVGGLWNVNLGYSCQPVKDAISAQLDRLP
YYSTFRGTSNDAAIELSYELSQFFAPDGLSRAFFTSGGSDSVETSLRLARQYHKLRGEPGRVKFLSLKKGYHGTHMGGAS
VNGNANFRTAYEPLLPGCYHIPAPYTYRNPFNETDPERLAQLCAQALEDEIAFQGASTIAAMIMEPILGAGGVIPPHKSF
APMVAEICARSGILLITDEVITAYGRTGAWTGARLWGIQPDMMATAKAITNGYFPFGAVMLGDRMVETFENNASAKIGHG
YTYSGHPVGAAAALACLAETQRLNVTENATARGTQLYEGCLALQEKYDVIGDVRGGHGLMTAIEMVSDRETKAPDAASGG
AVQEVAYQNGAMVRVSGPNLILSPPLILTEDDAATILSALDKGFASL

Specific function: Unknown

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=421, Percent_Identity=26.3657957244656, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI37574042, Length=421, Percent_Identity=27.3159144893112, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI226442709, Length=394, Percent_Identity=27.9187817258883, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI226442705, Length=393, Percent_Identity=27.735368956743, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI13994255, Length=393, Percent_Identity=28.2442748091603, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI24119277, Length=435, Percent_Identity=25.9770114942529, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI284507298, Length=333, Percent_Identity=28.5285285285285, Blast_Score=117, Evalue=3e-26,
Organism=Escherichia coli, GI145693181, Length=414, Percent_Identity=30.4347826086957, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1786991, Length=436, Percent_Identity=30.045871559633, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1789016, Length=428, Percent_Identity=28.0373831775701, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1789759, Length=401, Percent_Identity=27.930174563591, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI1788044, Length=410, Percent_Identity=27.8048780487805, Blast_Score=141, Evalue=9e-35,
Organism=Escherichia coli, GI1787560, Length=378, Percent_Identity=26.4550264550265, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1786349, Length=340, Percent_Identity=27.3529411764706, Blast_Score=98, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI32564660, Length=443, Percent_Identity=26.86230248307, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71992977, Length=433, Percent_Identity=27.0207852193995, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI25144271, Length=423, Percent_Identity=24.113475177305, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI25144274, Length=282, Percent_Identity=26.241134751773, Blast_Score=95, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6324386, Length=470, Percent_Identity=26.1702127659574, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6324432, Length=360, Percent_Identity=26.9444444444444, Blast_Score=121, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6323470, Length=427, Percent_Identity=25.2927400468384, Blast_Score=119, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6321456, Length=448, Percent_Identity=24.3303571428571, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI161085790, Length=442, Percent_Identity=28.0542986425339, Blast_Score=138, Evalue=8e-33,
Organism=Drosophila melanogaster, GI28574759, Length=438, Percent_Identity=27.8538812785388, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI21356575, Length=419, Percent_Identity=28.1622911694511, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI21357415, Length=446, Percent_Identity=25.3363228699552, Blast_Score=124, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 47960; Mature: 47960

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDSNFLKENNGRLMWHPMTSPKDSIDTPPKIVTEGHGVRIKDIDGHEVVDAVGGLWNVN
CCCCCCEECCCCEEEEECCCCCCCCCCCCCCEEECCCCEEEEECCCHHHHHHHCCEEECC
LGYSCQPVKDAISAQLDRLPYYSTFRGTSNDAAIELSYELSQFFAPDGLSRAFFTSGGSD
CCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEEHHHHHCCCCCCCHHHCCCCCCC
SVETSLRLARQYHKLRGEPGRVKFLSLKKGYHGTHMGGASVNGNANFRTAYEPLLPGCYH
HHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEECHHHHCCCCEE
IPAPYTYRNPFNETDPERLAQLCAQALEDEIAFQGASTIAAMIMEPILGAGGVIPPHKSF
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCH
APMVAEICARSGILLITDEVITAYGRTGAWTGARLWGIQPDMMATAKAITNGYFPFGAVM
HHHHHHHHHCCCEEEEEHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHCCCCCHHHHH
LGDRMVETFENNASAKIGHGYTYSGHPVGAAAALACLAETQRLNVTENATARGTQLYEGC
HHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
LALQEKYDVIGDVRGGHGLMTAIEMVSDRETKAPDAASGGAVQEVAYQNGAMVRVSGPNL
HHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCEEEECCCCE
ILSPPLILTEDDAATILSALDKGFASL
EECCCEEEECCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKDSNFLKENNGRLMWHPMTSPKDSIDTPPKIVTEGHGVRIKDIDGHEVVDAVGGLWNVN
CCCCCCEECCCCEEEEECCCCCCCCCCCCCCEEECCCCEEEEECCCHHHHHHHCCEEECC
LGYSCQPVKDAISAQLDRLPYYSTFRGTSNDAAIELSYELSQFFAPDGLSRAFFTSGGSD
CCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEEHHHHHCCCCCCCHHHCCCCCCC
SVETSLRLARQYHKLRGEPGRVKFLSLKKGYHGTHMGGASVNGNANFRTAYEPLLPGCYH
HHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEECHHHHCCCCEE
IPAPYTYRNPFNETDPERLAQLCAQALEDEIAFQGASTIAAMIMEPILGAGGVIPPHKSF
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCH
APMVAEICARSGILLITDEVITAYGRTGAWTGARLWGIQPDMMATAKAITNGYFPFGAVM
HHHHHHHHHCCCEEEEEHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHCCCCCHHHHH
LGDRMVETFENNASAKIGHGYTYSGHPVGAAAALACLAETQRLNVTENATARGTQLYEGC
HHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
LALQEKYDVIGDVRGGHGLMTAIEMVSDRETKAPDAASGGAVQEVAYQNGAMVRVSGPNL
HHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCEEEECCCCE
ILSPPLILTEDDAATILSALDKGFASL
EECCCEEEECCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]