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The map label for this gene is purE [H]

Identifier: 89055843

GI number: 89055843

Start: 3404527

End: 3405009

Strand: Direct

Name: purE [H]

Synonym: Jann_3352

Alternate gene names: 89055843

Gene position: 3404527-3405009 (Clockwise)

Preceding gene: 89055842

Following gene: 89055844

Centisome position: 78.85

GC content: 65.01

Gene sequence:

>483_bases
ATGGTTCAGGTCGCGATCATCATGGGCTCTCAATCGGATTGGCCCACCCTGCGGGAAGCGGCCGACATTCTCGATACGCT
GGGGGTGGCCTATGACGCGAAGATCGTTTCGGCTCACCGCACACCGGACCGCTTGTGGGACTTCGGCAAAGGCGCGGTGG
ATGCGGGCCTGAAAGTGATCATCGCAGGTGCAGGCGGGGCGGCGCATTTGCCTGGCATGGTGGCGTCGAAAACCCGCGTG
CCGGTGATCGGCGTACCGGTCCAGACCAAGGCACTTGGCGGCGTCGATAGCCTGTATTCCATCGTGCAGATGCCCAAAGG
CTACCCCGTGGCAACCATGGCGATCGGTGCGGCGGGGGCGGCAAATGCGGGCTTGATGGCGGCAGCGATCCTGGCCAATG
AAGACCCCGCCCTCGCCGCACGACTGGACCAGTGGCGCGCCGATCTGAGCGCCTCAATCCCGGAGGCCCCCAGCGATGAG
TGA

Upstream 100 bases:

>100_bases
TTGCCCGTGTCGAGGATGAGCTGACCCCCGATATCATTGCTTGAGGCCGCCTGCATCGCACGTATAGTGCGCGTTCGTTT
TACGCAAAGGACGGACGCCA

Downstream 100 bases:

>100_bases
TCCGTTACCGGCTGGCAGCACCGTCGGCATTCTGGGTGGCGGTCAGTTGGGCCGCATGTTGGCTATGGCCGCTGCGAACC
TCGGCTACCGGGCCCACATC

Product: phosphoribosylaminoimidazole carboxylase, catalytic subunit

Products: NA

Alternate protein names: N5-CAIR mutase; 5-(carboxyamino)imidazole ribonucleotide mutase [H]

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MVQVAIIMGSQSDWPTLREAADILDTLGVAYDAKIVSAHRTPDRLWDFGKGAVDAGLKVIIAGAGGAAHLPGMVASKTRV
PVIGVPVQTKALGGVDSLYSIVQMPKGYPVATMAIGAAGAANAGLMAAAILANEDPALAARLDQWRADLSASIPEAPSDE

Sequences:

>Translated_160_residues
MVQVAIIMGSQSDWPTLREAADILDTLGVAYDAKIVSAHRTPDRLWDFGKGAVDAGLKVIIAGAGGAAHLPGMVASKTRV
PVIGVPVQTKALGGVDSLYSIVQMPKGYPVATMAIGAAGAANAGLMAAAILANEDPALAARLDQWRADLSASIPEAPSDE
>Mature_160_residues
MVQVAIIMGSQSDWPTLREAADILDTLGVAYDAKIVSAHRTPDRLWDFGKGAVDAGLKVIIAGAGGAAHLPGMVASKTRV
PVIGVPVQTKALGGVDSLYSIVQMPKGYPVATMAIGAAGAANAGLMAAAILANEDPALAARLDQWRADLSASIPEAPSDE

Specific function: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) [H]

COG id: COG0041

COG function: function code F; Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AIR carboxylase family [H]

Homologues:

Organism=Escherichia coli, GI1786734, Length=155, Percent_Identity=60.6451612903226, Blast_Score=162, Evalue=9e-42,
Organism=Saccharomyces cerevisiae, GI6324702, Length=142, Percent_Identity=52.8169014084507, Blast_Score=144, Evalue=7e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000031 [H]

Pfam domain/function: PF00731 AIRC [H]

EC number: =5.4.99.18 [H]

Molecular weight: Translated: 16329; Mature: 16329

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQVAIIMGSQSDWPTLREAADILDTLGVAYDAKIVSAHRTPDRLWDFGKGAVDAGLKVI
CEEEEEEECCCCCCHHHHHHHHHHHHHCCHHCCEEEECCCCHHHHHHCCCCCCCCCEEEE
IAGAGGAAHLPGMVASKTRVPVIGVPVQTKALGGVDSLYSIVQMPKGYPVATMAIGAAGA
EECCCCCCCCCCCCCCCCCCCEEECCCCHHHHCCHHHHHHHHHCCCCCCCHHEEECCCCC
ANAGLMAAAILANEDPALAARLDQWRADLSASIPEAPSDE
CCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MVQVAIIMGSQSDWPTLREAADILDTLGVAYDAKIVSAHRTPDRLWDFGKGAVDAGLKVI
CEEEEEEECCCCCCHHHHHHHHHHHHHCCHHCCEEEECCCCHHHHHHCCCCCCCCCEEEE
IAGAGGAAHLPGMVASKTRVPVIGVPVQTKALGGVDSLYSIVQMPKGYPVATMAIGAAGA
EECCCCCCCCCCCCCCCCCCCEEECCCCHHHHCCHHHHHHHHHCCCCCCCHHEEECCCCC
ANAGLMAAAILANEDPALAARLDQWRADLSASIPEAPSDE
CCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3036807; 9384377 [H]