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The map label for this gene is fabH [H]

Identifier: 89055811

GI number: 89055811

Start: 3373414

End: 3374538

Strand: Direct

Name: fabH [H]

Synonym: Jann_3320

Alternate gene names: 89055811

Gene position: 3373414-3374538 (Clockwise)

Preceding gene: 89055810

Following gene: 89055812

Centisome position: 78.12

GC content: 60.27

Gene sequence:

>1125_bases
ATGTTTGAGCCAGCCATCACCGGATCAGGCGTTTTCACGCCCGATCAGAGCATTTCCAACGATGAACTTGTGGTGGCCTT
CAACGCCTATGCCGACCGCTGGAACGCCGAGAATGCCGCCGCGATCAAGGCCGGTGACGTCGACGCCATGGCCCATTCTT
CCTCTGAATTCATCGTTGCGGCCTCGGGCATCGAGTCGCGCTATGTGCTGGATAAGACGGGTCTTCTGGACCCCGATATC
ATGCATCCCCTGCTGCCGGAGCGCGCCATGGATCAGCCCGGCGTCATGGCCGAGATGGGCGTGGATGCCTGCCGCAAGGC
GCTTGATATGGCGGGGGTGGCAGCGGGCGACGTTGATGCGGTGATCTGTGCGGCCTCCAACCTGGAACGCGCCTACCCGG
CCATCGCCATCGAGATCCAGGAGGCGCTTGGCACCCGTGGCTTCGGGTTTGACATGAACGTCGCGTGTTCCTCGGCCACG
TTCGGGATACAGGCCGCCGCTGACATGATCCGGTCAGGCTCCATTCAACGGGCCCTGGTGGTGAACCCGGAGATCTGTTC
CGCCCATCTGGAATGGCGCGACCGTGATTGTCATTTCATTTTCGGCGACGTGGCCACGGCTGTTCTGATTGAGCGCAGCG
ATCTGGCCAAGGGCGAGAAATTCATCATCAAATCCACCCGCTGCGCCACCAAATTCTCCAACAATATCCGTAACAACAAC
GGCTTCCTGCGCCGCACGCGGGACGGTCACATGGACGACCGGCGCGACATGCTGTTCATGCAAAACGGGCGCAAGGTGTT
CAAGGAAGTGCTGCCGCTGGTCTCCAGACACATCGCCGAGCATATGGAGGATGCGGGCGTTCAGGCCGATGACCTCAAGC
GCCTCTGGCTGCATCAGGCCAACAAGACGATGAACGACTACATCGGAAAGAAGGTGCTGGGACGGGTGCCGGAGGCGGGC
GAACAGCCCAATATCCTGCAGGATTATGCCAACACCTCCTCTGCCGGGTCTATCATCGCATTCGCGAAATATTCCAATGA
CTTGGCCCCCGGCGATACGGGGCTGATCTGTTCATTCGGGGCCGGGTATTCGGTGGGGTCCGTGATCCTGGAAAAGACCG
CTTAG

Upstream 100 bases:

>100_bases
GCCTGGACGGCTGCGCCTGACGCCGCGGAATTGACCGGCCCACACCTTGACGCGGCTGCCCTTTCCCGCGCAAGAAAACA
GACCGGACCCGGAGAGCGAC

Downstream 100 bases:

>100_bases
AAATTGCGGCCACTTGCGCTAACGTGCGCGCGCATCACTACCGGAGCCGCCGCCCATGGCCGACCTGTCTCACCTCATCT
ATTCCTCCACGCCCTTCGGA

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MFEPAITGSGVFTPDQSISNDELVVAFNAYADRWNAENAAAIKAGDVDAMAHSSSEFIVAASGIESRYVLDKTGLLDPDI
MHPLLPERAMDQPGVMAEMGVDACRKALDMAGVAAGDVDAVICAASNLERAYPAIAIEIQEALGTRGFGFDMNVACSSAT
FGIQAAADMIRSGSIQRALVVNPEICSAHLEWRDRDCHFIFGDVATAVLIERSDLAKGEKFIIKSTRCATKFSNNIRNNN
GFLRRTRDGHMDDRRDMLFMQNGRKVFKEVLPLVSRHIAEHMEDAGVQADDLKRLWLHQANKTMNDYIGKKVLGRVPEAG
EQPNILQDYANTSSAGSIIAFAKYSNDLAPGDTGLICSFGAGYSVGSVILEKTA

Sequences:

>Translated_374_residues
MFEPAITGSGVFTPDQSISNDELVVAFNAYADRWNAENAAAIKAGDVDAMAHSSSEFIVAASGIESRYVLDKTGLLDPDI
MHPLLPERAMDQPGVMAEMGVDACRKALDMAGVAAGDVDAVICAASNLERAYPAIAIEIQEALGTRGFGFDMNVACSSAT
FGIQAAADMIRSGSIQRALVVNPEICSAHLEWRDRDCHFIFGDVATAVLIERSDLAKGEKFIIKSTRCATKFSNNIRNNN
GFLRRTRDGHMDDRRDMLFMQNGRKVFKEVLPLVSRHIAEHMEDAGVQADDLKRLWLHQANKTMNDYIGKKVLGRVPEAG
EQPNILQDYANTSSAGSIIAFAKYSNDLAPGDTGLICSFGAGYSVGSVILEKTA
>Mature_374_residues
MFEPAITGSGVFTPDQSISNDELVVAFNAYADRWNAENAAAIKAGDVDAMAHSSSEFIVAASGIESRYVLDKTGLLDPDI
MHPLLPERAMDQPGVMAEMGVDACRKALDMAGVAAGDVDAVICAASNLERAYPAIAIEIQEALGTRGFGFDMNVACSSAT
FGIQAAADMIRSGSIQRALVVNPEICSAHLEWRDRDCHFIFGDVATAVLIERSDLAKGEKFIIKSTRCATKFSNNIRNNN
GFLRRTRDGHMDDRRDMLFMQNGRKVFKEVLPLVSRHIAEHMEDAGVQADDLKRLWLHQANKTMNDYIGKKVLGRVPEAG
EQPNILQDYANTSSAGSIIAFAKYSNDLAPGDTGLICSFGAGYSVGSVILEKTA

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=336, Percent_Identity=26.7857142857143, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 40474; Mature: 40474

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEPAITGSGVFTPDQSISNDELVVAFNAYADRWNAENAAAIKAGDVDAMAHSSSEFIVA
CCCCCCCCCCCCCCCCCCCCCCEEEEEECHHCCCCCCCCEEEECCCCHHHHCCCCCEEEE
ASGIESRYVLDKTGLLDPDIMHPLLPERAMDQPGVMAEMGVDACRKALDMAGVAAGDVDA
ECCCCCEEEECCCCCCCHHHHHHCCCHHHCCCCCCHHHHCHHHHHHHHHHHCCCCCCCCE
VICAASNLERAYPAIAIEIQEALGTRGFGFDMNVACSSATFGIQAAADMIRSGSIQRALV
EEEEHHCHHHHCCEEEEEEHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCEEEE
VNPEICSAHLEWRDRDCHFIFGDVATAVLIERSDLAKGEKFIIKSTRCATKFSNNIRNNN
ECHHHHHHCCCCCCCCCCEEEHHHHHHHHHCCHHHCCCCEEEEECHHHHHHHHHCCCCCC
GFLRRTRDGHMDDRRDMLFMQNGRKVFKEVLPLVSRHIAEHMEDAGVQADDLKRLWLHQA
CCEEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
NKTMNDYIGKKVLGRVPEAGEQPNILQDYANTSSAGSIIAFAKYSNDLAPGDTGLICSFG
CCHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCEEEEEECCCCCCCCCCCEEEECC
AGYSVGSVILEKTA
CCCCHHHHHEECCC
>Mature Secondary Structure
MFEPAITGSGVFTPDQSISNDELVVAFNAYADRWNAENAAAIKAGDVDAMAHSSSEFIVA
CCCCCCCCCCCCCCCCCCCCCCEEEEEECHHCCCCCCCCEEEECCCCHHHHCCCCCEEEE
ASGIESRYVLDKTGLLDPDIMHPLLPERAMDQPGVMAEMGVDACRKALDMAGVAAGDVDA
ECCCCCEEEECCCCCCCHHHHHHCCCHHHCCCCCCHHHHCHHHHHHHHHHHCCCCCCCCE
VICAASNLERAYPAIAIEIQEALGTRGFGFDMNVACSSATFGIQAAADMIRSGSIQRALV
EEEEHHCHHHHCCEEEEEEHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCEEEE
VNPEICSAHLEWRDRDCHFIFGDVATAVLIERSDLAKGEKFIIKSTRCATKFSNNIRNNN
ECHHHHHHCCCCCCCCCCEEEHHHHHHHHHCCHHHCCCCEEEEECHHHHHHHHHCCCCCC
GFLRRTRDGHMDDRRDMLFMQNGRKVFKEVLPLVSRHIAEHMEDAGVQADDLKRLWLHQA
CCEEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
NKTMNDYIGKKVLGRVPEAGEQPNILQDYANTSSAGSIIAFAKYSNDLAPGDTGLICSFG
CCHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCEEEEEECCCCCCCCCCCEEEECC
AGYSVGSVILEKTA
CCCCHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA