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The map label for this gene is appC [H]

Identifier: 89055316

GI number: 89055316

Start: 2840383

End: 2841357

Strand: Direct

Name: appC [H]

Synonym: Jann_2825

Alternate gene names: 89055316

Gene position: 2840383-2841357 (Clockwise)

Preceding gene: 89055315

Following gene: 89055317

Centisome position: 65.78

GC content: 64.21

Gene sequence:

>975_bases
ATGAGCGATACGCCCCAGACGCCCGAGCAGCCCACCCCCGCCGTGCCCGCCGCCCGCGCGCAATCGCGCCTCTACCGCGC
GTGGGACAGTGATGTCGGCTACGCCTTCCGTCATTCCCCCGTGGCGCTGGTTTCGGCCAGCCTGACCGTCATCCTGATCC
TGGCGGCTGTCTTCGCGCCGCTCATTGCCCCCTATGACCCGTTCAACCCCGCATCCCTGAACCTGATGAACGGGCTGACG
CCGCCCGGCACGCCGTCGCCCTTCACCGGGGACAGCTTCATTCTGGGCACCGATGATCAGGGGCGCGATGTGTTCTCCAC
CATCCTCTACGGGTTGCGGATATCGCTGTTTGTGGGTTTTGCAGCCGTGACCTTCGCGCTTGTTCTGGGCGTTTCCCTTG
GCCTTATTGCGGGCTATGTCGGCGGGTGGACCGAGACGATCATCATGCGCATCGCCGATATCCAGCTGACCTTCCCGTCG
ATCCTTGTGGCGCTGCTGATCTCTGGCATCGCCAAGGGAGTGACCCCCATCGAATACCGCGATGAGATGGCGTTGTTCGT
GCTGATCCTCGCCATTGGCCTGTCGGATTGGGTGCAATTCGCACGGGTGGTGCGCGGGGCGACGCTGGTGGAAAAGAACA
AGGAATACGTGCAGGCCGCCCGCCTCATCGGGCGATCAACATTCGTCATCATGGCCCGCCACATCCTGCCCAACGTCCTA
TCACCCGTGCTGGTGATCGCCACCATTTCGCTGGCGCTGGCCATCATCGCCGAGGCAACGCTGTCCTTCCTCGGCGTCGG
TGCCCCGCCCACGGAACCCTCCCTCGGCACGCTGATCCGCATCGGCCAGACGTTCCTGTTCTCCGGCAAATGGTGGATCC
TTGTCTTCCCCGCCGCCACGCTCCTCGTGCTGGCACTGGCCGTAAATTTGCTCGGCGACTGGCTCCGCGACGCGATCAAC
CCGAGGCTGCGGTGA

Upstream 100 bases:

>100_bases
ATCTGATGCTGATTTCCGTGATGTTCGTGGGCATCAATCTGGCGGTGGACCTGCTTTATGTGGCGATTGACCCGCGCCTG
CGCGTGGATGGGAAAACGAC

Downstream 100 bases:

>100_bases
TGCGCTTCGCGCCCCTCCTCGCTACGCTCCTCGCAGTTACTCCCGTGGCCGCGCAGGAAACTGAATATGATCCGGAAGGG
GCGGTGCTTTGCAGCTATGC

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MSDTPQTPEQPTPAVPAARAQSRLYRAWDSDVGYAFRHSPVALVSASLTVILILAAVFAPLIAPYDPFNPASLNLMNGLT
PPGTPSPFTGDSFILGTDDQGRDVFSTILYGLRISLFVGFAAVTFALVLGVSLGLIAGYVGGWTETIIMRIADIQLTFPS
ILVALLISGIAKGVTPIEYRDEMALFVLILAIGLSDWVQFARVVRGATLVEKNKEYVQAARLIGRSTFVIMARHILPNVL
SPVLVIATISLALAIIAEATLSFLGVGAPPTEPSLGTLIRIGQTFLFSGKWWILVFPAATLLVLALAVNLLGDWLRDAIN
PRLR

Sequences:

>Translated_324_residues
MSDTPQTPEQPTPAVPAARAQSRLYRAWDSDVGYAFRHSPVALVSASLTVILILAAVFAPLIAPYDPFNPASLNLMNGLT
PPGTPSPFTGDSFILGTDDQGRDVFSTILYGLRISLFVGFAAVTFALVLGVSLGLIAGYVGGWTETIIMRIADIQLTFPS
ILVALLISGIAKGVTPIEYRDEMALFVLILAIGLSDWVQFARVVRGATLVEKNKEYVQAARLIGRSTFVIMARHILPNVL
SPVLVIATISLALAIIAEATLSFLGVGAPPTEPSLGTLIRIGQTFLFSGKWWILVFPAATLLVLALAVNLLGDWLRDAIN
PRLR
>Mature_323_residues
SDTPQTPEQPTPAVPAARAQSRLYRAWDSDVGYAFRHSPVALVSASLTVILILAAVFAPLIAPYDPFNPASLNLMNGLTP
PGTPSPFTGDSFILGTDDQGRDVFSTILYGLRISLFVGFAAVTFALVLGVSLGLIAGYVGGWTETIIMRIADIQLTFPSI
LVALLISGIAKGVTPIEYRDEMALFVLILAIGLSDWVQFARVVRGATLVEKNKEYVQAARLIGRSTFVIMARHILPNVLS
PVLVIATISLALAIIAEATLSFLGVGAPPTEPSLGTLIRIGQTFLFSGKWWILVFPAATLLVLALAVNLLGDWLRDAINP
RLR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=295, Percent_Identity=38.9830508474576, Blast_Score=174, Evalue=5e-45,
Organism=Escherichia coli, GI1787760, Length=289, Percent_Identity=33.9100346020761, Blast_Score=160, Evalue=9e-41,
Organism=Escherichia coli, GI1789964, Length=291, Percent_Identity=39.1752577319588, Blast_Score=150, Evalue=9e-38,
Organism=Escherichia coli, GI1787498, Length=300, Percent_Identity=34.3333333333333, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1789889, Length=258, Percent_Identity=30.2325581395349, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1787549, Length=275, Percent_Identity=31.2727272727273, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788505, Length=239, Percent_Identity=32.2175732217573, Blast_Score=99, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34737; Mature: 34606

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTPQTPEQPTPAVPAARAQSRLYRAWDSDVGYAFRHSPVALVSASLTVILILAAVFAP
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHH
LIAPYDPFNPASLNLMNGLTPPGTPSPFTGDSFILGTDDQGRDVFSTILYGLRISLFVGF
HHCCCCCCCCCCHHHHCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHH
AAVTFALVLGVSLGLIAGYVGGWTETIIMRIADIQLTFPSILVALLISGIAKGVTPIEYR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
DEMALFVLILAIGLSDWVQFARVVRGATLVEKNKEYVQAARLIGRSTFVIMARHILPNVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
SPVLVIATISLALAIIAEATLSFLGVGAPPTEPSLGTLIRIGQTFLFSGKWWILVFPAAT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHEECCCEEEEEHHHHH
LLVLALAVNLLGDWLRDAINPRLR
HHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SDTPQTPEQPTPAVPAARAQSRLYRAWDSDVGYAFRHSPVALVSASLTVILILAAVFAP
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHH
LIAPYDPFNPASLNLMNGLTPPGTPSPFTGDSFILGTDDQGRDVFSTILYGLRISLFVGF
HHCCCCCCCCCCHHHHCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHH
AAVTFALVLGVSLGLIAGYVGGWTETIIMRIADIQLTFPSILVALLISGIAKGVTPIEYR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
DEMALFVLILAIGLSDWVQFARVVRGATLVEKNKEYVQAARLIGRSTFVIMARHILPNVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
SPVLVIATISLALAIIAEATLSFLGVGAPPTEPSLGTLIRIGQTFLFSGKWWILVFPAAT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHEECCCEEEEEHHHHH
LLVLALAVNLLGDWLRDAINPRLR
HHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]