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The map label for this gene is lrp [H]

Identifier: 89055265

GI number: 89055265

Start: 2790224

End: 2790676

Strand: Reverse

Name: lrp [H]

Synonym: Jann_2774

Alternate gene names: 89055265

Gene position: 2790676-2790224 (Counterclockwise)

Preceding gene: 89055267

Following gene: 89055263

Centisome position: 64.63

GC content: 58.72

Gene sequence:

>453_bases
ATGACGAAGATTGATCAAAAAGACCGCTATATATTGCGTGAACTATCACGAGATGGACGGATATCGAACCTTGATCTGGC
CGAGCGTGTTGCGCTTTCGCCGTCGGCCACGTTGCGCCGGGTGCAGGCCCTGGAGGCAGCGGGTGTGATCTCTGGCTACC
GCGCCGTTCTTGATCCGGTCGCCATGGGGGTTGGGTTCATTGCTTATATTACAGTGGGTTTGGGTCTCCACACGAAGGCC
GCGCAAGAGGCGTTCGAGGTCGCAGTTGCCCGCGCGCCCGAGGTCGTGGAATGCCATAACATCACCGGAACGGTCGAATA
TCTGCTGCGCGTCGAAGTGGCGGATCTGGTGGCCTACAAGCGGTTCCATACGGACGTTCTGGGGGCATTGCCGCAGGTGG
CCACCATCACAACCTTTGTTGTCATGGGCTCACCCAAAGACACGCGCGCCTGA

Upstream 100 bases:

>100_bases
CAAGGCCGGTAAAGAGTTCATAAGTCATGACGCAACTTTAGAAAGGAGTGCGGCGAATGAAATTGCGAAGTTGGCGAACA
TGGCATAGAATACACAACAA

Downstream 100 bases:

>100_bases
CATTGTGATAGAAAAAAGGCGGTGACGATGTTCTGGGAGGAAGACATCATCACCGCCGAAATCTGGCCCGCCCAATGGGA
GGAAAGGGCAGGGCCGTCGT

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MTKIDQKDRYILRELSRDGRISNLDLAERVALSPSATLRRVQALEAAGVISGYRAVLDPVAMGVGFIAYITVGLGLHTKA
AQEAFEVAVARAPEVVECHNITGTVEYLLRVEVADLVAYKRFHTDVLGALPQVATITTFVVMGSPKDTRA

Sequences:

>Translated_150_residues
MTKIDQKDRYILRELSRDGRISNLDLAERVALSPSATLRRVQALEAAGVISGYRAVLDPVAMGVGFIAYITVGLGLHTKA
AQEAFEVAVARAPEVVECHNITGTVEYLLRVEVADLVAYKRFHTDVLGALPQVATITTFVVMGSPKDTRA
>Mature_149_residues
TKIDQKDRYILRELSRDGRISNLDLAERVALSPSATLRRVQALEAAGVISGYRAVLDPVAMGVGFIAYITVGLGLHTKAA
QEAFEVAVARAPEVVECHNITGTVEYLLRVEVADLVAYKRFHTDVLGALPQVATITTFVVMGSPKDTRA

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=145, Percent_Identity=39.3103448275862, Blast_Score=115, Evalue=1e-27,
Organism=Escherichia coli, GI87081742, Length=145, Percent_Identity=31.0344827586207, Blast_Score=82, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 16268; Mature: 16137

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKIDQKDRYILRELSRDGRISNLDLAERVALSPSATLRRVQALEAAGVISGYRAVLDPV
CCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AMGVGFIAYITVGLGLHTKAAQEAFEVAVARAPEVVECHNITGTVEYLLRVEVADLVAYK
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHH
RFHTDVLGALPQVATITTFVVMGSPKDTRA
HHHHHHHHHCCHHHHHHHHEEECCCCCCCC
>Mature Secondary Structure 
TKIDQKDRYILRELSRDGRISNLDLAERVALSPSATLRRVQALEAAGVISGYRAVLDPV
CCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AMGVGFIAYITVGLGLHTKAAQEAFEVAVARAPEVVECHNITGTVEYLLRVEVADLVAYK
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHH
RFHTDVLGALPQVATITTFVVMGSPKDTRA
HHHHHHHHHCCHHHHHHHHEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]