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The map label for this gene is cobT [H]

Identifier: 89055233

GI number: 89055233

Start: 2754345

End: 2756225

Strand: Direct

Name: cobT [H]

Synonym: Jann_2742

Alternate gene names: 89055233

Gene position: 2754345-2756225 (Clockwise)

Preceding gene: 89055232

Following gene: 89055234

Centisome position: 63.79

GC content: 64.49

Gene sequence:

>1881_bases
ATGAGCAAGTTCAACCCCTCCGACAACCCCGCCGACCCGTTCAAGAAGGCGCTCGCCGACGCGACGCGGGTGATGGCCGA
TGATCCTGAACTGGCGGTGACATACACGGTGGACCCGCCCGGGCTCAGCGGCGATAGCGTGCGCTTGCCCCAGGTCAGCC
GCCGGATGACCCGGGAGGAAGTCTTGCTGGCCCGCGGCACGGCCGACGCGCTGGCGCTGCGCCACAAATACCACGACCAT
GGCACCGCCAGCCGTTATGCCCCCCAGGGCGCGATGGCGCGCGACCTGATGGACGCAATGGAAAGCGCCCGGTGCGAGGC
CATGGGGGCCCGCGACATGCCCGGCACTGCCAGCAACATTGACGCCAAGATCGGCAATGAGGCGCGGCGAAAGGGCTATG
GAGAGATCCGCGACGCCACCGACGCCCCCCTATCCACTGCGGCGGGCTATCTGATCCGGCACCTCGCTACGGGGCGCGAT
CTGCCGCCTGAGGCGGCCAATGTCATGGAGCTCTGGCGCGGATTTATCGAGGATCGCTGCGACGGCACGTTGGAGGATTT
GCAGGACGTTCTGTCCAACCAGACCTCGTTTGCGAAATTCGCCCGGCAGTTGATTGATGATCTGGGGTATGGCGACCAAT
TGGGCGACGATCCCGACGATATCGATGAGGATGCCGAGGACGACGCGGGCGAGGACAGCGAAGACGACGCGCCGGACTCG
ACCGGTGAGGACGACAATGATGACGAGGAGGCGGAAGCCTCTCCCGAGCGGTCCCAGGAAGAGCAGCAGGACGCCTCCCA
GGCTCAGGTCGAAATGGACGACAACGGCGAGATGGAAGAGGCCGAGGAGCAGGAATTGCCCGACGGCGAGGCCCCGCAAG
AGCCTTTGCCGCCTGCCCCCCACTCCGACGCGGACCCGGATTACGTGGTGTTTTCCACGGAAAACGACGAGGAAATCGCC
GCAGAGGATTTGGCGGAGGCGCAGGAATTGGAACGCCTGCGGGCCTATCTGGACCAGCAGCTGGACCCGCTGAAGGGCGC
AGTCTCGCGCCTTGCGAACAAATTGCAGCGCCGCTTGCAGGCGCAACAGAACCGATCCTGGGAGTTTGACCGCGAGGAAG
GCATTCTGGATGCGGGGCGCCTCGCGCGCGTTGTGGCGAACCCGACCACGCCCCTGTCGTTTAAGGTCGAACACGACACA
GAGTTCCGGGACACGGTCGTGACGCTGCTGCTGGACAATTCCGGCTCCATGCGCGGGCGACCGATTTCCATTGCCGCAAT
CTGCGCGGACGTGCTGGCCCGAACCCTGGAGCGCTGCGGCGTGAAGGTGGAAATTCTGGGCTTCACGACGCGCGCCTGGA
AGGGCGGTAAGGCGCGGGAGGAATGGTTGGGCGAAGGGCGACCACAGCAGCCCGGACGCCTGAACGACCTACGCCATATC
GTCTATAAGTCTGCCGATGCGCCGTGGCGACGGGTGCGCGACAATCTTGGCCTGATGATGAAAGAGGGCCTGCTGAAGGA
AAATATCGACGGCGAGGCACTGGAATGGGCGCACCGACGGATGGTGGGCCGCACAGAGGCGCGCAAGATCCTGATGGTGA
TCTCGGACGGGGCGCCGGTCGATGACAGTACGCTGTCGGTGAACCCCGCGAACTATCTGGAAAAGCACCTGCGTGACGTG
ATCGCCATGGTCGAAAAGCGCCGCGCGGTGGAGCTGTTGGCGATTGGCATCGGCCATGACGTCACCCGCTATTATGAGCG
GGCGGTGACAATCACCGATGCGGAGCAATTGGCGGGGGCCATCACAGAGCAGCTTGCATCCTTGTTTGATGCTGATCCCC
GTGCGCGGGCCCGCGTGATGGGGATGAAACGGGCGGGCTGA

Upstream 100 bases:

>100_bases
CCCCTGCGAGGCTGCGCTGGACGCCTGGTTTGCGGCTGCCCCGCGGTAAAAGCGCCCCGCAGCACTTGCCCTTGCTCCTG
TGTCGGTCCAGATATCGGGG

Downstream 100 bases:

>100_bases
CGGCCCCAAGATCCATTTGATGTGGCGCCCGCGCCTTCGGCTTGGGCGCGGTGGCAGCTGCGCGGCGCAAAGGAGATCCG
CATGTTTCAGACCTTCACCG

Product: cobalt chelatase, CobT subunit

Products: NA

Alternate protein names: Hydrogenobyrinic acid a,c-diamide cobaltochelatase subunit CobT [H]

Number of amino acids: Translated: 626; Mature: 625

Protein sequence:

>626_residues
MSKFNPSDNPADPFKKALADATRVMADDPELAVTYTVDPPGLSGDSVRLPQVSRRMTREEVLLARGTADALALRHKYHDH
GTASRYAPQGAMARDLMDAMESARCEAMGARDMPGTASNIDAKIGNEARRKGYGEIRDATDAPLSTAAGYLIRHLATGRD
LPPEAANVMELWRGFIEDRCDGTLEDLQDVLSNQTSFAKFARQLIDDLGYGDQLGDDPDDIDEDAEDDAGEDSEDDAPDS
TGEDDNDDEEAEASPERSQEEQQDASQAQVEMDDNGEMEEAEEQELPDGEAPQEPLPPAPHSDADPDYVVFSTENDEEIA
AEDLAEAQELERLRAYLDQQLDPLKGAVSRLANKLQRRLQAQQNRSWEFDREEGILDAGRLARVVANPTTPLSFKVEHDT
EFRDTVVTLLLDNSGSMRGRPISIAAICADVLARTLERCGVKVEILGFTTRAWKGGKAREEWLGEGRPQQPGRLNDLRHI
VYKSADAPWRRVRDNLGLMMKEGLLKENIDGEALEWAHRRMVGRTEARKILMVISDGAPVDDSTLSVNPANYLEKHLRDV
IAMVEKRRAVELLAIGIGHDVTRYYERAVTITDAEQLAGAITEQLASLFDADPRARARVMGMKRAG

Sequences:

>Translated_626_residues
MSKFNPSDNPADPFKKALADATRVMADDPELAVTYTVDPPGLSGDSVRLPQVSRRMTREEVLLARGTADALALRHKYHDH
GTASRYAPQGAMARDLMDAMESARCEAMGARDMPGTASNIDAKIGNEARRKGYGEIRDATDAPLSTAAGYLIRHLATGRD
LPPEAANVMELWRGFIEDRCDGTLEDLQDVLSNQTSFAKFARQLIDDLGYGDQLGDDPDDIDEDAEDDAGEDSEDDAPDS
TGEDDNDDEEAEASPERSQEEQQDASQAQVEMDDNGEMEEAEEQELPDGEAPQEPLPPAPHSDADPDYVVFSTENDEEIA
AEDLAEAQELERLRAYLDQQLDPLKGAVSRLANKLQRRLQAQQNRSWEFDREEGILDAGRLARVVANPTTPLSFKVEHDT
EFRDTVVTLLLDNSGSMRGRPISIAAICADVLARTLERCGVKVEILGFTTRAWKGGKAREEWLGEGRPQQPGRLNDLRHI
VYKSADAPWRRVRDNLGLMMKEGLLKENIDGEALEWAHRRMVGRTEARKILMVISDGAPVDDSTLSVNPANYLEKHLRDV
IAMVEKRRAVELLAIGIGHDVTRYYERAVTITDAEQLAGAITEQLASLFDADPRARARVMGMKRAG
>Mature_625_residues
SKFNPSDNPADPFKKALADATRVMADDPELAVTYTVDPPGLSGDSVRLPQVSRRMTREEVLLARGTADALALRHKYHDHG
TASRYAPQGAMARDLMDAMESARCEAMGARDMPGTASNIDAKIGNEARRKGYGEIRDATDAPLSTAAGYLIRHLATGRDL
PPEAANVMELWRGFIEDRCDGTLEDLQDVLSNQTSFAKFARQLIDDLGYGDQLGDDPDDIDEDAEDDAGEDSEDDAPDST
GEDDNDDEEAEASPERSQEEQQDASQAQVEMDDNGEMEEAEEQELPDGEAPQEPLPPAPHSDADPDYVVFSTENDEEIAA
EDLAEAQELERLRAYLDQQLDPLKGAVSRLANKLQRRLQAQQNRSWEFDREEGILDAGRLARVVANPTTPLSFKVEHDTE
FRDTVVTLLLDNSGSMRGRPISIAAICADVLARTLERCGVKVEILGFTTRAWKGGKAREEWLGEGRPQQPGRLNDLRHIV
YKSADAPWRRVRDNLGLMMKEGLLKENIDGEALEWAHRRMVGRTEARKILMVISDGAPVDDSTLSVNPANYLEKHLRDVI
AMVEKRRAVELLAIGIGHDVTRYYERAVTITDAEQLAGAITEQLASLFDADPRARARVMGMKRAG

Specific function: Catalyzes cobalt insertion in the corrin ring [H]

COG id: COG4547

COG function: function code H; Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 VWFA domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006538
- InterPro:   IPR002035 [H]

Pfam domain/function: PF06213 CobT [H]

EC number: =6.6.1.2 [H]

Molecular weight: Translated: 69218; Mature: 69087

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: PS50234 VWFA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKFNPSDNPADPFKKALADATRVMADDPELAVTYTVDPPGLSGDSVRLPQVSRRMTREE
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCEECCHHHHHHHHHH
VLLARGTADALALRHKYHDHGTASRYAPQGAMARDLMDAMESARCEAMGARDMPGTASNI
HHHHCCCHHHHHHHHHHHCCCCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
DAKIGNEARRKGYGEIRDATDAPLSTAAGYLIRHLATGRDLPPEAANVMELWRGFIEDRC
CHHCCCHHHHCCCCHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHC
DGTLEDLQDVLSNQTSFAKFARQLIDDLGYGDQLGDDPDDIDEDAEDDAGEDSEDDAPDS
CCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TGEDDNDDEEAEASPERSQEEQQDASQAQVEMDDNGEMEEAEEQELPDGEAPQEPLPPAP
CCCCCCCCCHHHCCCHHHHHHHHHHHHCEEEECCCCCHHHHHHHCCCCCCCCCCCCCCCC
HSDADPDYVVFSTENDEEIAAEDLAEAQELERLRAYLDQQLDPLKGAVSRLANKLQRRLQ
CCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AQQNRSWEFDREEGILDAGRLARVVANPTTPLSFKVEHDTEFRDTVVTLLLDNSGSMRGR
HHHCCCCCCCHHCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHEEEEEECCCCCCCCC
PISIAAICADVLARTLERCGVKVEILGFTTRAWKGGKAREEWLGEGRPQQPGRLNDLRHI
CHHHHHHHHHHHHHHHHHCCCEEEEEEEEHHCCCCCCHHHHHHCCCCCCCCCHHHHHHHH
VYKSADAPWRRVRDNLGLMMKEGLLKENIDGEALEWAHRRMVGRTEARKILMVISDGAPV
HHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCEEEEEEECCCCC
DDSTLSVNPANYLEKHLRDVIAMVEKRRAVELLAIGIGHDVTRYYERAVTITDAEQLAGA
CCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEECCHHHHHHH
ITEQLASLFDADPRARARVMGMKRAG
HHHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKFNPSDNPADPFKKALADATRVMADDPELAVTYTVDPPGLSGDSVRLPQVSRRMTREE
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCEECCHHHHHHHHHH
VLLARGTADALALRHKYHDHGTASRYAPQGAMARDLMDAMESARCEAMGARDMPGTASNI
HHHHCCCHHHHHHHHHHHCCCCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
DAKIGNEARRKGYGEIRDATDAPLSTAAGYLIRHLATGRDLPPEAANVMELWRGFIEDRC
CHHCCCHHHHCCCCHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHC
DGTLEDLQDVLSNQTSFAKFARQLIDDLGYGDQLGDDPDDIDEDAEDDAGEDSEDDAPDS
CCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TGEDDNDDEEAEASPERSQEEQQDASQAQVEMDDNGEMEEAEEQELPDGEAPQEPLPPAP
CCCCCCCCCHHHCCCHHHHHHHHHHHHCEEEECCCCCHHHHHHHCCCCCCCCCCCCCCCC
HSDADPDYVVFSTENDEEIAAEDLAEAQELERLRAYLDQQLDPLKGAVSRLANKLQRRLQ
CCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AQQNRSWEFDREEGILDAGRLARVVANPTTPLSFKVEHDTEFRDTVVTLLLDNSGSMRGR
HHHCCCCCCCHHCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHEEEEEECCCCCCCCC
PISIAAICADVLARTLERCGVKVEILGFTTRAWKGGKAREEWLGEGRPQQPGRLNDLRHI
CHHHHHHHHHHHHHHHHHCCCEEEEEEEEHHCCCCCCHHHHHHCCCCCCCCCHHHHHHHH
VYKSADAPWRRVRDNLGLMMKEGLLKENIDGEALEWAHRRMVGRTEARKILMVISDGAPV
HHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCEEEEEEECCCCC
DDSTLSVNPANYLEKHLRDVIAMVEKRRAVELLAIGIGHDVTRYYERAVTITDAEQLAGA
CCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEECCHHHHHHH
ITEQLASLFDADPRARARVMGMKRAG
HHHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1917840 [H]