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The map label for this gene is aat

Identifier: 89055208

GI number: 89055208

Start: 2726033

End: 2726671

Strand: Direct

Name: aat

Synonym: Jann_2717

Alternate gene names: 89055208

Gene position: 2726033-2726671 (Clockwise)

Preceding gene: 89055207

Following gene: 89055212

Centisome position: 63.13

GC content: 61.19

Gene sequence:

>639_bases
ATGGCGCATGACATGTATCCCCAGCCACGCCCCCTTCTTACGCCGGACCTGATGATCCGCGCCTATGCCGCTGGCATTTT
CCCGATGTCCGAGGGCGCTGACAATCCAGAGGTGTTCTGGGTTGACCCTCAGCGGCGCGGCGTCTTCCCGCTCAACGGGT
TCCATATCTCTCGCACGCTGCGGCGGCAGATCAGGTTTGGCGGCTACAGCGTTCATATCAATCGGGATTTCGCTGGCGTT
TTAGATGGGTGTGCGGATCGGGAACCCACCTGGATCAATGCTGATCTGACCGCCTGTTACCTCGCGCTCCATGCCCAGGG
CCTGGCCCATTCGGTTGAGATCTGGGACGATGAGGGGCTGGCCGGAGCGGTTTTCGGCGTGACCTTGGGGGCAGCATTTT
TTGGCGAAAGCATGTTTTCGCGTCGCACCGGGGGGTCCAAACTGGCCCTCGCCCATCTGATCCACCGCCTGCGCGCTGGC
GGCTTTACGCTGTTTGACACGCAGTTTGTGACCGACCACCTCATGAGCCTTGGCGCGTTTGAGCTGCCCCGGTCGGACTA
CCGGGCCGAGTTGAGCCATGCGTTGCAACTACCTGCCGATTTCATGTCATTGCCGGAAGACGTCCCGCTGGTCGTCTAG

Upstream 100 bases:

>100_bases
CTCTGTTAATGCCGGGTTAAGGGCAGAGAGAAAAATCGAAACATCTACGTTTTGCCAAGTTATTATGGGCTTTTTTACGC
AGAAGGCCTAGGTGTCATTT

Downstream 100 bases:

>100_bases
GTTACGCCGAACAGCCCAAAACCCAGACGTCGTAGCGGGAATGCTCCAACGCATTCAGGGCCGGGCTGGACGCGATCATC
CATCCGTCAAAAAGCGTCTC

Product: leucyl/phenylalanyl-tRNA--protein transferase

Products: NA

Alternate protein names: L/F-transferase; Leucyltransferase; Phenyalanyltransferase

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MAHDMYPQPRPLLTPDLMIRAYAAGIFPMSEGADNPEVFWVDPQRRGVFPLNGFHISRTLRRQIRFGGYSVHINRDFAGV
LDGCADREPTWINADLTACYLALHAQGLAHSVEIWDDEGLAGAVFGVTLGAAFFGESMFSRRTGGSKLALAHLIHRLRAG
GFTLFDTQFVTDHLMSLGAFELPRSDYRAELSHALQLPADFMSLPEDVPLVV

Sequences:

>Translated_212_residues
MAHDMYPQPRPLLTPDLMIRAYAAGIFPMSEGADNPEVFWVDPQRRGVFPLNGFHISRTLRRQIRFGGYSVHINRDFAGV
LDGCADREPTWINADLTACYLALHAQGLAHSVEIWDDEGLAGAVFGVTLGAAFFGESMFSRRTGGSKLALAHLIHRLRAG
GFTLFDTQFVTDHLMSLGAFELPRSDYRAELSHALQLPADFMSLPEDVPLVV
>Mature_211_residues
AHDMYPQPRPLLTPDLMIRAYAAGIFPMSEGADNPEVFWVDPQRRGVFPLNGFHISRTLRRQIRFGGYSVHINRDFAGVL
DGCADREPTWINADLTACYLALHAQGLAHSVEIWDDEGLAGAVFGVTLGAAFFGESMFSRRTGGSKLALAHLIHRLRAGG
FTLFDTQFVTDHLMSLGAFELPRSDYRAELSHALQLPADFMSLPEDVPLVV

Specific function: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine

COG id: COG2360

COG function: function code O; Leu/Phe-tRNA-protein transferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the L/F-transferase family

Homologues:

Organism=Escherichia coli, GI1787111, Length=193, Percent_Identity=39.8963730569948, Blast_Score=129, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LFTR_JANSC (Q28NS8)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_510659.1
- ProteinModelPortal:   Q28NS8
- SMR:   Q28NS8
- STRING:   Q28NS8
- GeneID:   3935181
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_2717
- eggNOG:   COG2360
- HOGENOM:   HBG485363
- OMA:   GEPILWW
- PhylomeDB:   Q28NS8
- ProtClustDB:   PRK00301
- BioCyc:   JSP290400:JANN_2717-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00688
- InterPro:   IPR016181
- InterPro:   IPR004616
- TIGRFAMs:   TIGR00667

Pfam domain/function: PF03588 Leu_Phe_trans; SSF55729 Acyl_CoA_acyltransferase

EC number: =2.3.2.6

Molecular weight: Translated: 23473; Mature: 23342

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHDMYPQPRPLLTPDLMIRAYAAGIFPMSEGADNPEVFWVDPQRRGVFPLNGFHISRTL
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHH
RRQIRFGGYSVHINRDFAGVLDGCADREPTWINADLTACYLALHAQGLAHSVEIWDDEGL
HHHHHCCCEEEEECCCHHHHHHCCCCCCCCEEECHHHHHHHHHHHHCCCCEEEEECCCCC
AGAVFGVTLGAAFFGESMFSRRTGGSKLALAHLIHRLRAGGFTLFDTQFVTDHLMSLGAF
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCCC
ELPRSDYRAELSHALQLPADFMSLPEDVPLVV
CCCCHHHHHHHHHHHHCCHHHHCCCCCCCCCC
>Mature Secondary Structure 
AHDMYPQPRPLLTPDLMIRAYAAGIFPMSEGADNPEVFWVDPQRRGVFPLNGFHISRTL
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHH
RRQIRFGGYSVHINRDFAGVLDGCADREPTWINADLTACYLALHAQGLAHSVEIWDDEGL
HHHHHCCCEEEEECCCHHHHHHCCCCCCCCEEECHHHHHHHHHHHHCCCCEEEEECCCCC
AGAVFGVTLGAAFFGESMFSRRTGGSKLALAHLIHRLRAGGFTLFDTQFVTDHLMSLGAF
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCCC
ELPRSDYRAELSHALQLPADFMSLPEDVPLVV
CCCCHHHHHHHHHHHHCCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA