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The map label for this gene is aatA [H]

Identifier: 89055145

GI number: 89055145

Start: 2666365

End: 2667567

Strand: Direct

Name: aatA [H]

Synonym: Jann_2654

Alternate gene names: 89055145

Gene position: 2666365-2667567 (Clockwise)

Preceding gene: 89055141

Following gene: 89055147

Centisome position: 61.75

GC content: 60.93

Gene sequence:

>1203_bases
ATGCCCTTCCTTTCCGACACGCTTGCCCGGGTCAAACCTTCGCCCACGATTGCCGTCACCAACCTCGCCAATGAGCTGAA
GGCTCAGGGCAAGGACGTGATCGGGCTGGGGGCCGGTGAGCCGGACTTCGACACGCCGCAAAACATCAAGGATGCCGCAC
AGGCGGCGATCAATGCGGGCAAGACGAAGTATACGGCCGTGGACGGTATTGTGGAGTTGAAAGAGGCCATCGTCGCAAAG
CTCAAGCGCGATAATGACCTGTCGTATCAGACGTCTCAGGTGACCGTCGGCACCGGCGGCAAGCAGATCCTTTACAACGC
GCTGATGGCGACGCTGAACGCGGGTGATGAAGTGATCATCCCCGCGCCCTATTGGGTGTCCTACCCCGATATGGTGCTGC
TGGCCGGGGGGGAGCCGGTGTTCGTGGAAGGCCCAAGCCAGACCGGCTACAAGATCACGGCCGAGCAGTTGGAAGAGGCG
ATCACACCGAACACCAAATGGTTCATCTTCAATTCGCCCTCCAACCCCACCGGCGCGGGCTACACGGCCCATGAGTTGAA
GCAGTTGACCGATGTTTTGCTGCGTCATCCGCATGTTTGGGTGATGACTGACGACATGTACGAACACCTCGTCTACGATG
ATTTCCAGTTCGCCACCCCCGCCCAGGTGGAACCGCAATTGATGGGCCGCACGCTGACCTGTAACGGCGTGTCCAAGGCC
TATGCGATGACCGGCTGGCGTATCGGATATGCGGCAGGCCCCGATGAGTTGATCAAGGCGATGCGCAAGGTGCAGTCGCA
ATCCACGTCCAACCCCTGTTCGATCTCGCAATGGGCCGCTGTGGAGGCCCTGAACGGCACGCAAGACTTCCTCGCGCCCA
ATAACGAGACCTTCAAGCGCCGCCGCAACCTGGTGGTGGAAATGCTGAACGCGGCAGACGGCATTGATTGCCCGACGCCT
GAAGGGGCCTTTTACGTCTACCCCTCCATCCACGGCTGCATCGGCAAAACCTCCGCCGGGGGCACCAAGATCGACACCGA
TGAGACGTTCGCCAAGGCGTTGTTGGAAGAGACCGGCGTAGCCGTCGTCTTCGGCGGCGCATTCGGCCTGTCGCCAGCGT
TCCGCGTGTCCTACGCGACCTCGGACGAGAACCTGAAAGAGGCCTGCACGCGCATCCAGACGTTCTGCGCGTCCCTGACC
TGA

Upstream 100 bases:

>100_bases
TCCCTCCTAGAGGTTGATCGCGCCTGAAGGCCGCTCTATGCAACCCCTACACGTAATATAGGCCCGTTTGCGCGGGCTCC
ATCCCAAAGGACGCGACACG

Downstream 100 bases:

>100_bases
ACCGTCCGATACGATGAGTTTAACGGGCGTCCCACTTGGGGCGCTCTTTTTTCGTTACGCAAATGCGGGCGCAGGTGCGC
GTATCAGGCCCCAGATCAGT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MPFLSDTLARVKPSPTIAVTNLANELKAQGKDVIGLGAGEPDFDTPQNIKDAAQAAINAGKTKYTAVDGIVELKEAIVAK
LKRDNDLSYQTSQVTVGTGGKQILYNALMATLNAGDEVIIPAPYWVSYPDMVLLAGGEPVFVEGPSQTGYKITAEQLEEA
ITPNTKWFIFNSPSNPTGAGYTAHELKQLTDVLLRHPHVWVMTDDMYEHLVYDDFQFATPAQVEPQLMGRTLTCNGVSKA
YAMTGWRIGYAAGPDELIKAMRKVQSQSTSNPCSISQWAAVEALNGTQDFLAPNNETFKRRRNLVVEMLNAADGIDCPTP
EGAFYVYPSIHGCIGKTSAGGTKIDTDETFAKALLEETGVAVVFGGAFGLSPAFRVSYATSDENLKEACTRIQTFCASLT

Sequences:

>Translated_400_residues
MPFLSDTLARVKPSPTIAVTNLANELKAQGKDVIGLGAGEPDFDTPQNIKDAAQAAINAGKTKYTAVDGIVELKEAIVAK
LKRDNDLSYQTSQVTVGTGGKQILYNALMATLNAGDEVIIPAPYWVSYPDMVLLAGGEPVFVEGPSQTGYKITAEQLEEA
ITPNTKWFIFNSPSNPTGAGYTAHELKQLTDVLLRHPHVWVMTDDMYEHLVYDDFQFATPAQVEPQLMGRTLTCNGVSKA
YAMTGWRIGYAAGPDELIKAMRKVQSQSTSNPCSISQWAAVEALNGTQDFLAPNNETFKRRRNLVVEMLNAADGIDCPTP
EGAFYVYPSIHGCIGKTSAGGTKIDTDETFAKALLEETGVAVVFGGAFGLSPAFRVSYATSDENLKEACTRIQTFCASLT
>Mature_399_residues
PFLSDTLARVKPSPTIAVTNLANELKAQGKDVIGLGAGEPDFDTPQNIKDAAQAAINAGKTKYTAVDGIVELKEAIVAKL
KRDNDLSYQTSQVTVGTGGKQILYNALMATLNAGDEVIIPAPYWVSYPDMVLLAGGEPVFVEGPSQTGYKITAEQLEEAI
TPNTKWFIFNSPSNPTGAGYTAHELKQLTDVLLRHPHVWVMTDDMYEHLVYDDFQFATPAQVEPQLMGRTLTCNGVSKAY
AMTGWRIGYAAGPDELIKAMRKVQSQSTSNPCSISQWAAVEALNGTQDFLAPNNETFKRRRNLVVEMLNAADGIDCPTPE
GAFYVYPSIHGCIGKTSAGGTKIDTDETFAKALLEETGVAVVFGGAFGLSPAFRVSYATSDENLKEACTRIQTFCASLT

Specific function: Required for symbiotic nitrogen fixation [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=375, Percent_Identity=28.5333333333333, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI169881279, Length=375, Percent_Identity=28.5333333333333, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI56713254, Length=316, Percent_Identity=28.1645569620253, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI56713256, Length=358, Percent_Identity=26.536312849162, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI169881281, Length=369, Percent_Identity=25.2032520325203, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI4507369, Length=400, Percent_Identity=25, Blast_Score=109, Evalue=5e-24,
Organism=Escherichia coli, GI1786816, Length=375, Percent_Identity=26.4, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1788627, Length=392, Percent_Identity=25.2551020408163, Blast_Score=131, Evalue=9e-32,
Organism=Escherichia coli, GI1788722, Length=366, Percent_Identity=30.6010928961749, Blast_Score=120, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17567663, Length=382, Percent_Identity=25.9162303664921, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71994472, Length=404, Percent_Identity=27.970297029703, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71994476, Length=404, Percent_Identity=27.970297029703, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17567369, Length=427, Percent_Identity=26.9320843091335, Blast_Score=105, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6322401, Length=312, Percent_Identity=29.1666666666667, Blast_Score=125, Evalue=8e-30,
Organism=Saccharomyces cerevisiae, GI6323118, Length=345, Percent_Identity=23.768115942029, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320317, Length=251, Percent_Identity=24.7011952191235, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28573069, Length=388, Percent_Identity=27.5773195876289, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24646114, Length=388, Percent_Identity=27.5773195876289, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI28573067, Length=388, Percent_Identity=27.5773195876289, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI28573065, Length=388, Percent_Identity=27.5773195876289, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI18859735, Length=395, Percent_Identity=23.0379746835443, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI45551451, Length=396, Percent_Identity=23.4848484848485, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641770, Length=396, Percent_Identity=23.4848484848485, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641760, Length=396, Percent_Identity=23.4848484848485, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641768, Length=396, Percent_Identity=23.4848484848485, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641766, Length=396, Percent_Identity=23.4848484848485, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641764, Length=396, Percent_Identity=23.4848484848485, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43155; Mature: 43024

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFLSDTLARVKPSPTIAVTNLANELKAQGKDVIGLGAGEPDFDTPQNIKDAAQAAINAG
CCCHHHHHHHCCCCCCEEEHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCC
KTKYTAVDGIVELKEAIVAKLKRDNDLSYQTSQVTVGTGGKQILYNALMATLNAGDEVII
CCEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCCEEE
PAPYWVSYPDMVLLAGGEPVFVEGPSQTGYKITAEQLEEAITPNTKWFIFNSPSNPTGAG
CCCCCCCCCCEEEEECCCEEEEECCCCCCCEEEHHHHHHHHCCCCEEEEEECCCCCCCCC
YTAHELKQLTDVLLRHPHVWVMTDDMYEHLVYDDFQFATPAQVEPQLMGRTLTCNGVSKA
CCHHHHHHHHHHHHHCCEEEEEECHHHHHHHHCCCCCCCCCCCCHHHCCCEEEECCCHHH
YAMTGWRIGYAAGPDELIKAMRKVQSQSTSNPCSISQWAAVEALNGTQDFLAPNNETFKR
HHHCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHCCCCCHHHHH
RRNLVVEMLNAADGIDCPTPEGAFYVYPSIHGCIGKTSAGGTKIDTDETFAKALLEETGV
HHHHHHHHHHHCCCCCCCCCCCCEEECCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCE
AVVFGGAFGLSPAFRVSYATSDENLKEACTRIQTFCASLT
EEEECCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PFLSDTLARVKPSPTIAVTNLANELKAQGKDVIGLGAGEPDFDTPQNIKDAAQAAINAG
CCHHHHHHHCCCCCCEEEHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCC
KTKYTAVDGIVELKEAIVAKLKRDNDLSYQTSQVTVGTGGKQILYNALMATLNAGDEVII
CCEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCCEEE
PAPYWVSYPDMVLLAGGEPVFVEGPSQTGYKITAEQLEEAITPNTKWFIFNSPSNPTGAG
CCCCCCCCCCEEEEECCCEEEEECCCCCCCEEEHHHHHHHHCCCCEEEEEECCCCCCCCC
YTAHELKQLTDVLLRHPHVWVMTDDMYEHLVYDDFQFATPAQVEPQLMGRTLTCNGVSKA
CCHHHHHHHHHHHHHCCEEEEEECHHHHHHHHCCCCCCCCCCCCHHHCCCEEEECCCHHH
YAMTGWRIGYAAGPDELIKAMRKVQSQSTSNPCSISQWAAVEALNGTQDFLAPNNETFKR
HHHCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHCCCCCHHHHH
RRNLVVEMLNAADGIDCPTPEGAFYVYPSIHGCIGKTSAGGTKIDTDETFAKALLEETGV
HHHHHHHHHHHCCCCCCCCCCCCEEECCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCE
AVVFGGAFGLSPAFRVSYATSDENLKEACTRIQTFCASLT
EEEECCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2019560; 8096210; 11481430 [H]