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The map label for this gene is purQ

Identifier: 89055034

GI number: 89055034

Start: 2548044

End: 2548712

Strand: Reverse

Name: purQ

Synonym: Jann_2543

Alternate gene names: 89055034

Gene position: 2548712-2548044 (Counterclockwise)

Preceding gene: 89055035

Following gene: 89055033

Centisome position: 59.03

GC content: 65.02

Gene sequence:

>669_bases
GTGAAAGCAGCCGTTCTCGTCTTCCCCGGCTCCAATTGTGACCGCGATCTGGCCGTGGGCTTCCGCAGCGCCGGGTTTGA
GGTGGAGATGGTCTGGCACAAGGAGACAGCGCTGCCTGCCGGCATTGACGTTGTGGGCATTCCGGGCGGGTTCTCCTACG
GAGATTACCTGCGCTGCGGGGCCATTGCCGCGCAATCGCCGATCATGCGCGCCGTGGCGGACTTTGCGGGGCAGGGCGGG
CATGTTCTGGGCGTCTGCAACGGGTTCCAGGTGTTGTGCGAAACGCGGCTCCTGCCGGGGGTGTTGATGCGCAACGGCGG
CATCAAGTTCGTGTGCCGGGCAGAGCCCCTTGTCGTGGCCAGTGCCACCAGCCCCTTCACTGATGGCTATTCCATCGGCG
ACCGGATCGCGGTGCCAGTGGCGCACCATGATGGGAACTACCAGATTGATGATGAGGGCCTGTCTGCCCTGCGGTCCGAA
GATCGCATCGCCTTCACCTATGCCGACAATCCCAATGGCTCACGCGCCGATATCGCAGGCGTGCTCAGCGCCAACCGGCG
GGTTTTGGGCATGATGCCTCACCCTGAACGCGCTGTGGATGTGGCCCATGGCGGCACCGACGGCAGCGTGCTGTTTGCGT
CGCTTGCGGCGGCGCTGGTGGCGGCCTGA

Upstream 100 bases:

>100_bases
GCACGACCGAGGCCCAGGTGCGTGAGATGTGCGAAAAGCTGCTCGCGAATACGGTGATCGAGAGCTACCGGGTTGAGATG
GCCAAGACAGGAGAAGACGC

Downstream 100 bases:

>100_bases
CCCGGTGATCCGACGCCGCCGCGCCCGCATCCTGCGGGCCGCCCCTTGAGGCGCGTCGTGGCGCGGCATAGTCTTCTTCC
ATGAGCTTTGCTGATCGTCC

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MKAAVLVFPGSNCDRDLAVGFRSAGFEVEMVWHKETALPAGIDVVGIPGGFSYGDYLRCGAIAAQSPIMRAVADFAGQGG
HVLGVCNGFQVLCETRLLPGVLMRNGGIKFVCRAEPLVVASATSPFTDGYSIGDRIAVPVAHHDGNYQIDDEGLSALRSE
DRIAFTYADNPNGSRADIAGVLSANRRVLGMMPHPERAVDVAHGGTDGSVLFASLAAALVAA

Sequences:

>Translated_222_residues
MKAAVLVFPGSNCDRDLAVGFRSAGFEVEMVWHKETALPAGIDVVGIPGGFSYGDYLRCGAIAAQSPIMRAVADFAGQGG
HVLGVCNGFQVLCETRLLPGVLMRNGGIKFVCRAEPLVVASATSPFTDGYSIGDRIAVPVAHHDGNYQIDDEGLSALRSE
DRIAFTYADNPNGSRADIAGVLSANRRVLGMMPHPERAVDVAHGGTDGSVLFASLAAALVAA
>Mature_222_residues
MKAAVLVFPGSNCDRDLAVGFRSAGFEVEMVWHKETALPAGIDVVGIPGGFSYGDYLRCGAIAAQSPIMRAVADFAGQGG
HVLGVCNGFQVLCETRLLPGVLMRNGGIKFVCRAEPLVVASATSPFTDGYSIGDRIAVPVAHHDGNYQIDDEGLSALRSE
DRIAFTYADNPNGSRADIAGVLSANRRVLGMMPHPERAVDVAHGGTDGSVLFASLAAALVAA

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain

Homologues:

Organism=Escherichia coli, GI48994899, Length=225, Percent_Identity=34.2222222222222, Blast_Score=80, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6321498, Length=237, Percent_Identity=31.6455696202532, Blast_Score=75, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24582111, Length=231, Percent_Identity=31.6017316017316, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24582109, Length=231, Percent_Identity=31.6017316017316, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17137292, Length=231, Percent_Identity=31.6017316017316, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PURQ_JANSC (Q28PA2)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_510485.1
- ProteinModelPortal:   Q28PA2
- SMR:   Q28PA2
- STRING:   Q28PA2
- GeneID:   3935006
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_2543
- eggNOG:   COG0047
- HOGENOM:   HBG302712
- OMA:   FPGTNCD
- BioCyc:   JSP290400:JANN_2543-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00421
- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075
- PIRSF:   PIRSF001586
- TIGRFAMs:   TIGR01737

Pfam domain/function: PF07685 GATase_3

EC number: =6.3.5.3

Molecular weight: Translated: 23146; Mature: 23146

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS51273 GATASE_TYPE_1

Important sites: ACT_SITE 86-86 ACT_SITE 194-194 ACT_SITE 196-196

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAAVLVFPGSNCDRDLAVGFRSAGFEVEMVWHKETALPAGIDVVGIPGGFSYGDYLRCG
CCEEEEEECCCCCCCHHEEEEECCCEEEEEEEECCCCCCCCCEEEECCCCCCCCCHHHHC
AIAAQSPIMRAVADFAGQGGHVLGVCNGFQVLCETRLLPGVLMRNGGIKFVCRAEPLVVA
HHHHCCHHHHHHHHHCCCCCEEEEEECCHHHHHHHHCCCCEEEECCCEEEEEECCCEEEE
SATSPFTDGYSIGDRIAVPVAHHDGNYQIDDEGLSALRSEDRIAFTYADNPNGSRADIAG
ECCCCCCCCCCCCCEEEEEEEECCCCEEECHHHHHHHCCCCCEEEEECCCCCCCHHHHEE
VLSANRRVLGMMPHPERAVDVAHGGTDGSVLFASLAAALVAA
EECCCCEEEECCCCCHHEEEEECCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKAAVLVFPGSNCDRDLAVGFRSAGFEVEMVWHKETALPAGIDVVGIPGGFSYGDYLRCG
CCEEEEEECCCCCCCHHEEEEECCCEEEEEEEECCCCCCCCCEEEECCCCCCCCCHHHHC
AIAAQSPIMRAVADFAGQGGHVLGVCNGFQVLCETRLLPGVLMRNGGIKFVCRAEPLVVA
HHHHCCHHHHHHHHHCCCCCEEEEEECCHHHHHHHHCCCCEEEECCCEEEEEECCCEEEE
SATSPFTDGYSIGDRIAVPVAHHDGNYQIDDEGLSALRSEDRIAFTYADNPNGSRADIAG
ECCCCCCCCCCCCCEEEEEEEECCCCEEECHHHHHHHCCCCCEEEEECCCCCCCHHHHEE
VLSANRRVLGMMPHPERAVDVAHGGTDGSVLFASLAAALVAA
EECCCCEEEECCCCCHHEEEEECCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA