Click here to switch to the map view.

The map label for this gene is frr [H]

Identifier: 89054949

GI number: 89054949

Start: 2451884

End: 2452615

Strand: Reverse

Name: frr [H]

Synonym: Jann_2458

Alternate gene names: 89054949

Gene position: 2452615-2451884 (Counterclockwise)

Preceding gene: 89054950

Following gene: 89054948

Centisome position: 56.8

GC content: 61.07

Gene sequence:

>732_bases
ATGTCACGATTGCCCTGTCGCCGGTGGTTTGCCGGACGCTTTAGAGCGCGCGTCCGCCTAAGGGGCACTTGCACGGCGCA
TCCTTACCGTGAAGCCTCCGGTCGTAGGGTGTTGCCGACCCAAGCGCACACGGGTTACAAGCGCTGCAATTGGAAAACCA
AAACAGGCAGTCCCGATATGTCCGATGACTTCATGCTCGACACCGATGATCTGGAGCGGCGAATGGAAGGGGCGATTGCG
TCCCTGCGCACAGAATTCGCGTCGCTGCGCACCGGGCGCGCGTCGGCCTCCATGCTGGAGCCGGTCATGGTGGACGCATA
TGGTGCGATGACGCCGATCAACCAGGTGGGCACCGTCAATGTGCCCGAGCCGCGGATGGTCACGGTGAACGTCTGGGACA
AGGGCCTGGTGAACAAGGTCGAGAAGGCCATTCGTGAATCCGGTCTGGGCATCAACCCCCAGATGAACGGCACGATCATC
ATGCTGCCGATCCCGGAGTTGAACGAGGAGCGCCGCCGCGAGCTGACCAAGGTTGCAGGCACCTATGCCGAAAACGCCCG
TGTCGCCGTGCGCAATGTGCGCCGTGACGGGATGGACCAGATCAAGAAGGCCGACACATCCGAGGACGACGCGAAGTTCT
GGGAAGGGGCGGTGCAGGAGCTGACAGACACCTTCATCAAGCGGGTCGATGATCAGTTAGAGACCAAGCAGGAAGAGATC
ATGCAGGTCTGA

Upstream 100 bases:

>100_bases
CGGCATGACTGCGGAACAGGAGGCGCGATTGCTTGACACGGCACAGTGATTTACGCCCCGCGCTGTCGCGGACAACCGAC
CGGAGTTTCGATGCCGCCGG

Downstream 100 bases:

>100_bases
TCGATCCGCGCGCCGCTGGGGCAACCGGAGGATTTCCGGCCTTGCCCCGCAGCGGATCGACACATCATTTCCGGACGTGC
CTTGAAAGGACAGTCCCTAT

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MSRLPCRRWFAGRFRARVRLRGTCTAHPYREASGRRVLPTQAHTGYKRCNWKTKTGSPDMSDDFMLDTDDLERRMEGAIA
SLRTEFASLRTGRASASMLEPVMVDAYGAMTPINQVGTVNVPEPRMVTVNVWDKGLVNKVEKAIRESGLGINPQMNGTII
MLPIPELNEERRRELTKVAGTYAENARVAVRNVRRDGMDQIKKADTSEDDAKFWEGAVQELTDTFIKRVDDQLETKQEEI
MQV

Sequences:

>Translated_243_residues
MSRLPCRRWFAGRFRARVRLRGTCTAHPYREASGRRVLPTQAHTGYKRCNWKTKTGSPDMSDDFMLDTDDLERRMEGAIA
SLRTEFASLRTGRASASMLEPVMVDAYGAMTPINQVGTVNVPEPRMVTVNVWDKGLVNKVEKAIRESGLGINPQMNGTII
MLPIPELNEERRRELTKVAGTYAENARVAVRNVRRDGMDQIKKADTSEDDAKFWEGAVQELTDTFIKRVDDQLETKQEEI
MQV
>Mature_242_residues
SRLPCRRWFAGRFRARVRLRGTCTAHPYREASGRRVLPTQAHTGYKRCNWKTKTGSPDMSDDFMLDTDDLERRMEGAIAS
LRTEFASLRTGRASASMLEPVMVDAYGAMTPINQVGTVNVPEPRMVTVNVWDKGLVNKVEKAIRESGLGINPQMNGTIIM
LPIPELNEERRRELTKVAGTYAENARVAVRNVRRDGMDQIKKADTSEDDAKFWEGAVQELTDTFIKRVDDQLETKQEEIM
QV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=180, Percent_Identity=28.3333333333333, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI291042689, Length=154, Percent_Identity=31.8181818181818, Blast_Score=86, Evalue=3e-17,
Organism=Escherichia coli, GI1786368, Length=177, Percent_Identity=44.0677966101695, Blast_Score=152, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24661488, Length=179, Percent_Identity=26.2569832402235, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 27580; Mature: 27449

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLPCRRWFAGRFRARVRLRGTCTAHPYREASGRRVLPTQAHTGYKRCNWKTKTGSPDM
CCCCCHHHHHHHHHHEEEEEEECCCCCCCHHCCCCEECCCCCCCCHHHCCCCCCCCCCCC
SDDFMLDTDDLERRMEGAIASLRTEFASLRTGRASASMLEPVMVDAYGAMTPINQVGTVN
CCCCEECHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
VPEPRMVTVNVWDKGLVNKVEKAIRESGLGINPQMNGTIIMLPIPELNEERRRELTKVAG
CCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHH
TYAENARVAVRNVRRDGMDQIKKADTSEDDAKFWEGAVQELTDTFIKRVDDQLETKQEEI
HHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MQV
HCC
>Mature Secondary Structure 
SRLPCRRWFAGRFRARVRLRGTCTAHPYREASGRRVLPTQAHTGYKRCNWKTKTGSPDM
CCCCHHHHHHHHHHEEEEEEECCCCCCCHHCCCCEECCCCCCCCHHHCCCCCCCCCCCC
SDDFMLDTDDLERRMEGAIASLRTEFASLRTGRASASMLEPVMVDAYGAMTPINQVGTVN
CCCCEECHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
VPEPRMVTVNVWDKGLVNKVEKAIRESGLGINPQMNGTIIMLPIPELNEERRRELTKVAG
CCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHH
TYAENARVAVRNVRRDGMDQIKKADTSEDDAKFWEGAVQELTDTFIKRVDDQLETKQEEI
HHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MQV
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA