Click here to switch to the map view.

The map label for this gene is yfcG [H]

Identifier: 89054911

GI number: 89054911

Start: 2417611

End: 2418264

Strand: Direct

Name: yfcG [H]

Synonym: Jann_2420

Alternate gene names: 89054911

Gene position: 2417611-2418264 (Clockwise)

Preceding gene: 89054910

Following gene: 89054912

Centisome position: 55.99

GC content: 57.65

Gene sequence:

>654_bases
ATGATCGACTTTCACACGCACGCGACACCCAACGGCTTCAAGGTCGCCATCGCGCTTGAAGAAATGGGCCTTCCCTATGA
CGTTCACCTTGTGGACATGCGCGCGGGCGAACAGTTCGCACCCGAATTTGTCGCCATGAATCCCAATGCGAAACTGCCGG
TGATCGTTGATCACGACACGGGAACGACAGTCTACGAATCCAACGCCATTCTTGAATACCTCGCGACAAAGACCGGACAA
TTGATGCCCGCGCAGACCGATGCAGATTATTGGGAAGCCCGTCAGCTTCTGTACTTTCAGGCGGCGTCCGTCGGGCCATT
CTTCGGCCAACGCATGCACTTCTCCTACCTCGCGCCGGAAACGGTGCCCTACGGCATTGCGCGCTATGAAACCGAGGGGG
CACGGTTGCAGAAAGTCATGGACGATATGCTGGTAGGCCGTGATTATTTCCTCGCCAGTGGATATTCTATCGTCGATATC
GCACTGCTCGGGTGGTACATGACTGCCGTTCTGGCTGGGTATGACGATCCGGCCCACAAGAACCTCGCGGCTTGGCATCA
ACGGGTTTCTGATCGTCCGGCCGTGCAGGCGGGCCTTGGCGTGCCGATGCGCCGCGATCCTTCACAACTTCCACCGCGCA
AGGTGGTATCGTGA

Upstream 100 bases:

>100_bases
CTTGGTCGTTTCCTCGTCGTCAAACGCAAGGGCACCCACCTTCTCTCCAACATGTTCCCGAGCAGTTACGCCGCATCAAA
ATAGCAGAAGGATTGCATGA

Downstream 100 bases:

>100_bases
TTGCCTTCATAGTCCGCATCACAGCACATTCCGGTCAACGCGCCGCATTAGAAACGCTGACGAATGCGCTCTTTTCTGAT
CTGGCAGGCGAAGACGCCTT

Product: glutathione S-transferase-like protein

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MIDFHTHATPNGFKVAIALEEMGLPYDVHLVDMRAGEQFAPEFVAMNPNAKLPVIVDHDTGTTVYESNAILEYLATKTGQ
LMPAQTDADYWEARQLLYFQAASVGPFFGQRMHFSYLAPETVPYGIARYETEGARLQKVMDDMLVGRDYFLASGYSIVDI
ALLGWYMTAVLAGYDDPAHKNLAAWHQRVSDRPAVQAGLGVPMRRDPSQLPPRKVVS

Sequences:

>Translated_217_residues
MIDFHTHATPNGFKVAIALEEMGLPYDVHLVDMRAGEQFAPEFVAMNPNAKLPVIVDHDTGTTVYESNAILEYLATKTGQ
LMPAQTDADYWEARQLLYFQAASVGPFFGQRMHFSYLAPETVPYGIARYETEGARLQKVMDDMLVGRDYFLASGYSIVDI
ALLGWYMTAVLAGYDDPAHKNLAAWHQRVSDRPAVQAGLGVPMRRDPSQLPPRKVVS
>Mature_217_residues
MIDFHTHATPNGFKVAIALEEMGLPYDVHLVDMRAGEQFAPEFVAMNPNAKLPVIVDHDTGTTVYESNAILEYLATKTGQ
LMPAQTDADYWEARQLLYFQAASVGPFFGQRMHFSYLAPETVPYGIARYETEGARLQKVMDDMLVGRDYFLASGYSIVDI
ALLGWYMTAVLAGYDDPAHKNLAAWHQRVSDRPAVQAGLGVPMRRDPSQLPPRKVVS

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=204, Percent_Identity=39.2156862745098, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI87082195, Length=222, Percent_Identity=34.2342342342342, Blast_Score=119, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6324100, Length=150, Percent_Identity=37.3333333333333, Blast_Score=102, Evalue=6e-23,
Organism=Drosophila melanogaster, GI28571670, Length=175, Percent_Identity=30.2857142857143, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24646249, Length=180, Percent_Identity=28.3333333333333, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI17864598, Length=202, Percent_Identity=27.2277227722772, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 24184; Mature: 24184

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDFHTHATPNGFKVAIALEEMGLPYDVHLVDMRAGEQFAPEFVAMNPNAKLPVIVDHDT
CCCCCCCCCCCCEEEEEEEHHCCCCEEEEEEEECCCCCCCCEEEEECCCCCCCEEEECCC
GTTVYESNAILEYLATKTGQLMPAQTDADYWEARQLLYFQAASVGPFFGQRMHFSYLAPE
CCEEEECCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHEEHHCCCCCHHHCCEEEEEECCC
TVPYGIARYETEGARLQKVMDDMLVGRDYFLASGYSIVDIALLGWYMTAVLAGYDDPAHK
CCCCCCEEEECCHHHHHHHHHHHHHCCHHEEECCCHHHHHHHHHHHHHHHHHCCCCCCHH
NLAAWHQRVSDRPAVQAGLGVPMRRDPSQLPPRKVVS
HHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCHHCCC
>Mature Secondary Structure
MIDFHTHATPNGFKVAIALEEMGLPYDVHLVDMRAGEQFAPEFVAMNPNAKLPVIVDHDT
CCCCCCCCCCCCEEEEEEEHHCCCCEEEEEEEECCCCCCCCEEEEECCCCCCCEEEECCC
GTTVYESNAILEYLATKTGQLMPAQTDADYWEARQLLYFQAASVGPFFGQRMHFSYLAPE
CCEEEECCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHEEHHCCCCCHHHCCEEEEEECCC
TVPYGIARYETEGARLQKVMDDMLVGRDYFLASGYSIVDIALLGWYMTAVLAGYDDPAHK
CCCCCCEEEECCHHHHHHHHHHHHHCCHHEEECCCHHHHHHHHHHHHHHHHHCCCCCCHH
NLAAWHQRVSDRPAVQAGLGVPMRRDPSQLPPRKVVS
HHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]