Click here to switch to the map view.

The map label for this gene is dhmA2 [H]

Identifier: 89054843

GI number: 89054843

Start: 2358327

End: 2359271

Strand: Direct

Name: dhmA2 [H]

Synonym: Jann_2352

Alternate gene names: 89054843

Gene position: 2358327-2359271 (Clockwise)

Preceding gene: 89054842

Following gene: 89054844

Centisome position: 54.62

GC content: 66.24

Gene sequence:

>945_bases
ATGAAGATCGTCGTTACCGTCCTTGCGCTGCTGGTGATCTTCGCGGCCGTCACGATGTGGCGCGCCGCGCGCAATGAGGC
GCAGGCCGAGGCCGAGTATCCCCCCGCAGGCCAGTTCGTGACCGTGAACGGCACCCGCGTGCATTACATCGACGAAGGCG
ACGGCCCCGTTGTCGTGCTGCTCCATGGCTCTGGCGGCAACCTGAACGACTGGACCTTCGACATGGTCGGGCGGCTATCG
GACCGCTACCGGGTCATCGCGTTTGACCGCCCCGGTTTGGGCTACACGGATCCTCTCGGGGACAACACGCCTGTCACGGC
TCAGGCGCGCCTTCTGGCCGATGCCGCCCTCGCCCTTGGTGCAGACAACCCGATGGTTGTGGGCCATTCCTATGGCGGCG
CGGTTGCTGTCGCCTGGGGTGTCGAGCGGCCCGATGTGCTGGCGGGACTTGTGGTTCTGGCCGGCGCCACCAACCCGTGG
GAGGGCGGCATCAGCACCTATTACCGCATCCTGTCACATCCCATCGCCGGGCCGATCATGGCAAACCTGCTGGCCGCATG
GGTGCCCGAGCGCATCGTGACCGAGAATGTCGAGGCCGTCTTCACCCCGCAATCCGCGCCCGAGGGGTATGGCGACCATT
TCGGCCCCGGCCTGACCCTGCGGCGGTTTTCGCTTCTGGAAAATGCCCTGCAACGGGCCTCTCTCTTGCCGCAGGTCGAG
GCGATGGTGCCCGCCTACCCCAACATCGCGGTGCCGACGGAGATCCTCCATGGCGATGCCGACACGACCGTCGGCCTCCA
CGTCCACTCCGTCCCGCTCAGCGAACAGATCCCGGACGCTGTGTTGACCGTCCTGGACGGGGTTGGCCATATGCCCCAAC
ACGCTGAGCCTGAGATGCTGGTGGAGGCCATTGACCGCCTGACGGCACGTGCAGACCTGCGCTGA

Upstream 100 bases:

>100_bases
CCCATGCGCATCTTCTCTACGGCAATTGGGTGAGTGAACTTTACCTCACAACCCCTTATGATATCGAACAAATCGGCCTG
GCGTCCACGGATCTGCGCAA

Downstream 100 bases:

>100_bases
TCCGCCGTGACGTCGGGGCCTGTTTCATTGCGAACGGGGACGAGAGCCCCTAATGTAATAGTCAATAACATATCGCGAGA
GAGCAGGCCCACGCCATGAC

Product: alpha/beta hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MKIVVTVLALLVIFAAVTMWRAARNEAQAEAEYPPAGQFVTVNGTRVHYIDEGDGPVVVLLHGSGGNLNDWTFDMVGRLS
DRYRVIAFDRPGLGYTDPLGDNTPVTAQARLLADAALALGADNPMVVGHSYGGAVAVAWGVERPDVLAGLVVLAGATNPW
EGGISTYYRILSHPIAGPIMANLLAAWVPERIVTENVEAVFTPQSAPEGYGDHFGPGLTLRRFSLLENALQRASLLPQVE
AMVPAYPNIAVPTEILHGDADTTVGLHVHSVPLSEQIPDAVLTVLDGVGHMPQHAEPEMLVEAIDRLTARADLR

Sequences:

>Translated_314_residues
MKIVVTVLALLVIFAAVTMWRAARNEAQAEAEYPPAGQFVTVNGTRVHYIDEGDGPVVVLLHGSGGNLNDWTFDMVGRLS
DRYRVIAFDRPGLGYTDPLGDNTPVTAQARLLADAALALGADNPMVVGHSYGGAVAVAWGVERPDVLAGLVVLAGATNPW
EGGISTYYRILSHPIAGPIMANLLAAWVPERIVTENVEAVFTPQSAPEGYGDHFGPGLTLRRFSLLENALQRASLLPQVE
AMVPAYPNIAVPTEILHGDADTTVGLHVHSVPLSEQIPDAVLTVLDGVGHMPQHAEPEMLVEAIDRLTARADLR
>Mature_314_residues
MKIVVTVLALLVIFAAVTMWRAARNEAQAEAEYPPAGQFVTVNGTRVHYIDEGDGPVVVLLHGSGGNLNDWTFDMVGRLS
DRYRVIAFDRPGLGYTDPLGDNTPVTAQARLLADAALALGADNPMVVGHSYGGAVAVAWGVERPDVLAGLVVLAGATNPW
EGGISTYYRILSHPIAGPIMANLLAAWVPERIVTENVEAVFTPQSAPEGYGDHFGPGLTLRRFSLLENALQRASLLPQVE
AMVPAYPNIAVPTEILHGDADTTVGLHVHSVPLSEQIPDAVLTVLDGVGHMPQHAEPEMLVEAIDRLTARADLR

Specific function: Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the haloalkane dehalogenase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI218777840, Length=281, Percent_Identity=24.5551601423488, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI13376164, Length=281, Percent_Identity=24.5551601423488, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.8.1.5 [H]

Molecular weight: Translated: 33509; Mature: 33509

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVVTVLALLVIFAAVTMWRAARNEAQAEAEYPPAGQFVTVNGTRVHYIDEGDGPVVVL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCEEEEEECCCCCEEEE
LHGSGGNLNDWTFDMVGRLSDRYRVIAFDRPGLGYTDPLGDNTPVTAQARLLADAALALG
EECCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
ADNPMVVGHSYGGAVAVAWGVERPDVLAGLVVLAGATNPWEGGISTYYRILSHPIAGPIM
CCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHH
ANLLAAWVPERIVTENVEAVFTPQSAPEGYGDHFGPGLTLRRFSLLENALQRASLLPQVE
HHHHHHHCCHHHHHCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHH
AMVPAYPNIAVPTEILHGDADTTVGLHVHSVPLSEQIPDAVLTVLDGVGHMPQHAEPEML
HHCCCCCCCCCCHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCHHHH
VEAIDRLTARADLR
HHHHHHHHHHCCCC
>Mature Secondary Structure
MKIVVTVLALLVIFAAVTMWRAARNEAQAEAEYPPAGQFVTVNGTRVHYIDEGDGPVVVL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCEEEEEECCCCCEEEE
LHGSGGNLNDWTFDMVGRLSDRYRVIAFDRPGLGYTDPLGDNTPVTAQARLLADAALALG
EECCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
ADNPMVVGHSYGGAVAVAWGVERPDVLAGLVVLAGATNPWEGGISTYYRILSHPIAGPIM
CCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHH
ANLLAAWVPERIVTENVEAVFTPQSAPEGYGDHFGPGLTLRRFSLLENALQRASLLPQVE
HHHHHHHCCHHHHHCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHH
AMVPAYPNIAVPTEILHGDADTTVGLHVHSVPLSEQIPDAVLTVLDGVGHMPQHAEPEML
HHCCCCCCCCCCHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCHHHH
VEAIDRLTARADLR
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]