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The map label for this gene is speB [H]

Identifier: 89054831

GI number: 89054831

Start: 2346929

End: 2347894

Strand: Reverse

Name: speB [H]

Synonym: Jann_2340

Alternate gene names: 89054831

Gene position: 2347894-2346929 (Counterclockwise)

Preceding gene: 89054833

Following gene: 89054830

Centisome position: 54.37

GC content: 65.94

Gene sequence:

>966_bases
ATGGCACTGGAAGACGCAAAGACTGAGGTGGATGTCGCGATCACGCGGGCGGACCTGAAGGGCCTGTCCTATGAGAACGC
GTTCTCGGGCGCGCCGTCGTTTCTGCGGCGCAAATACACCAAGGATCTGACCGGTGTGGATGTGGCTGTGACGGGCATCC
CGTTTGATCAGGCGGTGACAAACAGGCCCGGCACGCGGCTGGGGCCCCGCGCGATCCGGGCCGCCTCCGCCCTGCAACCC
TTCGATCCGCCCTATGGGTGGGACGGCTATTCACCGCTGGAGGCGCTGGCCATCGCGGATTACGGCGATATGGCGTTCGA
CTATGCCCATACGGCAGATGTCCCGGAGCGGATTGAGGCGCATATCGCGGGCATTCTGGGGGCAGGGGCCGCAGTCATCA
CGTTGGGGGGCGATCACTCGATCACACTGCCGATCCTGCGCGCCCACGCCGCAATCCACGGGCCGCTCGCGTTGATCCAG
GTCGATGCCCACACCGATACCTGGCCCGATGATGATGCGGCGCGGATCGACCACGGGACGTTCTGCTACACGGCTGTGAA
GGAAGGGCTGATCGACGTCGCGCGGTCGTCGCATATCGGGATCCGAACGGTGGTGGAGGATAACCTCGGCATCCACATCC
ACGACGCTCGGGAGGTGCAGGAGCGTGGGGCATCCGCCGTCGCCGCTGCCGCCAAGGCGCGCGTGGGCGATGCGCCCGTC
TATCTCAGCTTTGATATCGACGGGCTGGACCCGGCCTTTGCGCCCGGCACCGGAACACCCGTCTGGGGCGGGCTGACATC
TGCGCAGGCCGCGATCCTTTTGCGCGATCTGGCGGGCATCAATCTGGTCGGCGGTGACGTGGTGGAAGTGTCGCCTCCGT
TTGACGTCTCCGAGATCACCGCCGTCGCAGGCGCCCATGTGGCGATGGAATTGCTGTGCCTGTGGGGCTGGACGCGGCGG
ACCTAG

Upstream 100 bases:

>100_bases
ATCGCCCACCACCGATCCCCGCACAAGATGGATCAATTCGGGGCTACGTCTCGCGATTTCTTCGGTATAGCAAGGGGGCA
GGGCAGCGAAGGGGCAGATC

Downstream 100 bases:

>100_bases
GCCTCCGTGATCGGCACCGTTACTTAAACGTCACTGGACCGAGCGCCTGGCAATCCTTACCTGTAGGACTGCACGCAGCT
GACAAGGCTCCCATGTCCCA

Product: agmatinase

Products: NA

Alternate protein names: Agmatine ureohydrolase; AUH [H]

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MALEDAKTEVDVAITRADLKGLSYENAFSGAPSFLRRKYTKDLTGVDVAVTGIPFDQAVTNRPGTRLGPRAIRAASALQP
FDPPYGWDGYSPLEALAIADYGDMAFDYAHTADVPERIEAHIAGILGAGAAVITLGGDHSITLPILRAHAAIHGPLALIQ
VDAHTDTWPDDDAARIDHGTFCYTAVKEGLIDVARSSHIGIRTVVEDNLGIHIHDAREVQERGASAVAAAAKARVGDAPV
YLSFDIDGLDPAFAPGTGTPVWGGLTSAQAAILLRDLAGINLVGGDVVEVSPPFDVSEITAVAGAHVAMELLCLWGWTRR
T

Sequences:

>Translated_321_residues
MALEDAKTEVDVAITRADLKGLSYENAFSGAPSFLRRKYTKDLTGVDVAVTGIPFDQAVTNRPGTRLGPRAIRAASALQP
FDPPYGWDGYSPLEALAIADYGDMAFDYAHTADVPERIEAHIAGILGAGAAVITLGGDHSITLPILRAHAAIHGPLALIQ
VDAHTDTWPDDDAARIDHGTFCYTAVKEGLIDVARSSHIGIRTVVEDNLGIHIHDAREVQERGASAVAAAAKARVGDAPV
YLSFDIDGLDPAFAPGTGTPVWGGLTSAQAAILLRDLAGINLVGGDVVEVSPPFDVSEITAVAGAHVAMELLCLWGWTRR
T
>Mature_320_residues
ALEDAKTEVDVAITRADLKGLSYENAFSGAPSFLRRKYTKDLTGVDVAVTGIPFDQAVTNRPGTRLGPRAIRAASALQPF
DPPYGWDGYSPLEALAIADYGDMAFDYAHTADVPERIEAHIAGILGAGAAVITLGGDHSITLPILRAHAAIHGPLALIQV
DAHTDTWPDDDAARIDHGTFCYTAVKEGLIDVARSSHIGIRTVVEDNLGIHIHDAREVQERGASAVAAAAKARVGDAPVY
LSFDIDGLDPAFAPGTGTPVWGGLTSAQAAILLRDLAGINLVGGDVVEVSPPFDVSEITAVAGAHVAMELLCLWGWTRRT

Specific function: Catalyzes the formation of putrescine from agmatine [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=292, Percent_Identity=39.7260273972603, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI10947139, Length=313, Percent_Identity=28.7539936102236, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI4502215, Length=314, Percent_Identity=28.6624203821656, Blast_Score=90, Evalue=2e-18,
Organism=Escherichia coli, GI1789306, Length=301, Percent_Identity=46.1794019933555, Blast_Score=233, Evalue=2e-62,
Organism=Saccharomyces cerevisiae, GI6325146, Length=219, Percent_Identity=30.1369863013699, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 33801; Mature: 33670

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALEDAKTEVDVAITRADLKGLSYENAFSGAPSFLRRKYTKDLTGVDVAVTGIPFDQAVT
CCCCCCCCCEEEEEEEEHHCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCHHHHHC
NRPGTRLGPRAIRAASALQPFDPPYGWDGYSPLEALAIADYGDMAFDYAHTADVPERIEA
CCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHEECCCCCHHCCCCCCCCCHHHHHH
HIAGILGAGAAVITLGGDHSITLPILRAHAAIHGPLALIQVDAHTDTWPDDDAARIDHGT
HHHHHHCCCEEEEEECCCCEEEHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCC
FCYTAVKEGLIDVARSSHIGIRTVVEDNLGIHIHDAREVQERGASAVAAAAKARVGDAPV
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEECHHHHHHCCHHHHHHHHHHCCCCCCE
YLSFDIDGLDPAFAPGTGTPVWGGLTSAQAAILLRDLAGINLVGGDVVEVSPPFDVSEIT
EEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCEEEECCCCCHHHHH
AVAGAHVAMELLCLWGWTRRT
HHHHHHHHHHHHHHHCHHCCC
>Mature Secondary Structure 
ALEDAKTEVDVAITRADLKGLSYENAFSGAPSFLRRKYTKDLTGVDVAVTGIPFDQAVT
CCCCCCCCEEEEEEEEHHCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCHHHHHC
NRPGTRLGPRAIRAASALQPFDPPYGWDGYSPLEALAIADYGDMAFDYAHTADVPERIEA
CCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHEECCCCCHHCCCCCCCCCHHHHHH
HIAGILGAGAAVITLGGDHSITLPILRAHAAIHGPLALIQVDAHTDTWPDDDAARIDHGT
HHHHHHCCCEEEEEECCCCEEEHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCC
FCYTAVKEGLIDVARSSHIGIRTVVEDNLGIHIHDAREVQERGASAVAAAAKARVGDAPV
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEECHHHHHHCCHHHHHHHHHHCCCCCCE
YLSFDIDGLDPAFAPGTGTPVWGGLTSAQAAILLRDLAGINLVGGDVVEVSPPFDVSEIT
EEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCEEEECCCCCHHHHH
AVAGAHVAMELLCLWGWTRRT
HHHHHHHHHHHHHHHCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]