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The map label for this gene is rhmA [H]

Identifier: 89054657

GI number: 89054657

Start: 2172619

End: 2173380

Strand: Direct

Name: rhmA [H]

Synonym: Jann_2166

Alternate gene names: 89054657

Gene position: 2172619-2173380 (Clockwise)

Preceding gene: 89054647

Following gene: 89054658

Centisome position: 50.32

GC content: 68.37

Gene sequence:

>762_bases
ATGCCCGCACCGATCAACACCCTGAAAGCGGCACTGGCGCGGGGCGAGCTCCAACGGGGGCTGTGGCTGAACCTGCCCGG
CGCCGTTCCGGCAGAGATGGCCGGCAATGCCGGATTCGACTGGTGCCTGATTGATGGAGAGCATGGGCCGTGGGATCCGT
CGGGCATCCGCGATCAGTTGATCGCCCTGGCGGCCACGCCCACGCCAGCCGTTCTGCGCGTCCCGGTGGCGGAGGACTGG
ATCATCAAGCAGGCGCTGGATCTGGGTGCGCAGACCCTCCTGATCCCCATGGTCAATTCGGCGCAGGAGGCGGAGGCTAT
CGTCCGCGCCTGCCGCTATCCGCCCGAGGGCACGCGCGGCATGGGCGCGATGGCGGCCCGGGTCGGTGGGTTTGGGGCGA
TTTCCGAATATCCTGCCACGGCCAACGACCAGATCTGCGTGTTGGTGCAGGCCGAAAGCCGCGCCGCGCTCGATAATCTG
GACGCGATCACCGCGGTCGAGGGCGTGGATGGTGTCTTCATCGGTCCCGCTGATCTGGGGGCGGACATGGGCTACCGCGA
CGATCTGGGCAATGGGGAGCTGTGGACGTTGATCGAAGATGGCATCGGCACGATCCGCGCGGGCGGCAAAGCGGCGGGCA
TCCTCGTCTCGGGCGCAGGGATGGAGGCGCGGATGCGGGCGGCGGGTGTCACGTTCATGGGCTGTGGTGGCGACGCAGGC
GTGTTGCAAGCGGGGCTGACCGCGCTGGCGCGCCCCTCATGA

Upstream 100 bases:

>100_bases
TGGCTGCCTTAACGGACCAGCACGTCGCCCGATGGTGCGGGCTTGCGCAGGCGCGGGGGATTTGATCGACTGAGCGGACG
TCAGCCACCCGGAGAACCCC

Downstream 100 bases:

>100_bases
TCCGGCTCAGGCATGGCGATGCGGAGGCGTTGATTGACCCTTCGGTCGGCAATATCCCCCGGTGGCAAGTCTCGGGCCGT
GTGCCGCTGCACGCCGCCCC

Product: 2-dehydro-3-deoxyglucarate aldolase

Products: NA

Alternate protein names: KDR aldolase; 2-dehydro-3-deoxyrhamnonate aldolase [H]

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MPAPINTLKAALARGELQRGLWLNLPGAVPAEMAGNAGFDWCLIDGEHGPWDPSGIRDQLIALAATPTPAVLRVPVAEDW
IIKQALDLGAQTLLIPMVNSAQEAEAIVRACRYPPEGTRGMGAMAARVGGFGAISEYPATANDQICVLVQAESRAALDNL
DAITAVEGVDGVFIGPADLGADMGYRDDLGNGELWTLIEDGIGTIRAGGKAAGILVSGAGMEARMRAAGVTFMGCGGDAG
VLQAGLTALARPS

Sequences:

>Translated_253_residues
MPAPINTLKAALARGELQRGLWLNLPGAVPAEMAGNAGFDWCLIDGEHGPWDPSGIRDQLIALAATPTPAVLRVPVAEDW
IIKQALDLGAQTLLIPMVNSAQEAEAIVRACRYPPEGTRGMGAMAARVGGFGAISEYPATANDQICVLVQAESRAALDNL
DAITAVEGVDGVFIGPADLGADMGYRDDLGNGELWTLIEDGIGTIRAGGKAAGILVSGAGMEARMRAAGVTFMGCGGDAG
VLQAGLTALARPS
>Mature_252_residues
PAPINTLKAALARGELQRGLWLNLPGAVPAEMAGNAGFDWCLIDGEHGPWDPSGIRDQLIALAATPTPAVLRVPVAEDWI
IKQALDLGAQTLLIPMVNSAQEAEAIVRACRYPPEGTRGMGAMAARVGGFGAISEYPATANDQICVLVQAESRAALDNLD
AITAVEGVDGVFIGPADLGADMGYRDDLGNGELWTLIEDGIGTIRAGGKAAGILVSGAGMEARMRAAGVTFMGCGGDAGV
LQAGLTALARPS

Specific function: Catalyzes the reversible retro-aldol cleavage of 2-keto- 3-deoxy-L-rhamnonate (KDR) to pyruvate and lactaldehyde [H]

COG id: COG3836

COG function: function code G; 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HpcH/HpaI aldolase family. KDR aldolase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788578, Length=233, Percent_Identity=49.7854077253219, Blast_Score=218, Evalue=2e-58,
Organism=Escherichia coli, GI1789514, Length=245, Percent_Identity=41.6326530612245, Blast_Score=191, Evalue=3e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005000
- InterPro:   IPR015813 [H]

Pfam domain/function: PF03328 HpcH_HpaI [H]

EC number: 4.1.2.-

Molecular weight: Translated: 25944; Mature: 25813

Theoretical pI: Translated: 4.22; Mature: 4.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAPINTLKAALARGELQRGLWLNLPGAVPAEMAGNAGFDWCLIDGEHGPWDPSGIRDQL
CCCCHHHHHHHHHHHHHHCCEEEECCCCCCHHHCCCCCCEEEEECCCCCCCCCCCHHHHE
IALAATPTPAVLRVPVAEDWIIKQALDLGAQTLLIPMVNSAQEAEAIVRACRYPPEGTRG
EEEECCCCCCEEEECCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCC
MGAMAARVGGFGAISEYPATANDQICVLVQAESRAALDNLDAITAVEGVDGVFIGPADLG
HHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCHHHHCCCHHHHCCCCCEEEECHHHHC
ADMGYRDDLGNGELWTLIEDGIGTIRAGGKAAGILVSGAGMEARMRAAGVTFMGCGGDAG
CCCCCCCCCCCCCEEEEEECCCCEEECCCCEEEEEEECCCCHHHHHHCCEEEEECCCCHH
VLQAGLTALARPS
HHHHHHHHHCCCC
>Mature Secondary Structure 
PAPINTLKAALARGELQRGLWLNLPGAVPAEMAGNAGFDWCLIDGEHGPWDPSGIRDQL
CCCHHHHHHHHHHHHHHCCEEEECCCCCCHHHCCCCCCEEEEECCCCCCCCCCCHHHHE
IALAATPTPAVLRVPVAEDWIIKQALDLGAQTLLIPMVNSAQEAEAIVRACRYPPEGTRG
EEEECCCCCCEEEECCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCC
MGAMAARVGGFGAISEYPATANDQICVLVQAESRAALDNLDAITAVEGVDGVFIGPADLG
HHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCHHHHCCCHHHHCCCCCEEEECHHHHC
ADMGYRDDLGNGELWTLIEDGIGTIRAGGKAAGILVSGAGMEARMRAAGVTFMGCGGDAG
CCCCCCCCCCCCCEEEEEECCCCEEECCCCEEEEEEECCCCHHHHHHCCEEEEECCCCHH
VLQAGLTALARPS
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA