Click here to switch to the map view.

The map label for this gene is hmuS [H]

Identifier: 89054624

GI number: 89054624

Start: 2141231

End: 2142286

Strand: Direct

Name: hmuS [H]

Synonym: Jann_2133

Alternate gene names: 89054624

Gene position: 2141231-2142286 (Clockwise)

Preceding gene: 89054617

Following gene: 89054625

Centisome position: 49.59

GC content: 63.73

Gene sequence:

>1056_bases
ATGGGCGCAGATACACTTCTTTCCGCCACCGGCATTCGGGCGGCGATTGCCGACAACCCCAAGACCCGCCCCCGTGATCT
GGCCGATACGCTCGGGGTGCCGGAGGCCGCGTTGCTGGCGGCGCAGATCGGCTATGGGGGCGTTCCGATGGTCGCTGACA
CCACCAAGCTGATCCCCGCGATTTGCACCCTGGGAGAGGTCATGGCCCTGACCCGCAATGACAGCGCGGTGCACGAGAAG
ATCGGCGTATACGACAATTTCCACCCCGGCGATCATGCGTCGTCTGTGTTGACGGCGGACATCGACCTGCGCCTGTTCTC
GCGTCACTGGGTCCATGCATTCGCGATGGAGAAAGAGGTGGACGGGACCGTCCGCCGCTCCGTTCAGGTGTTCGATGCGG
CGGGGGACGCGGTGCACAAGGTGATCCTGCGCGAGCGGTCCAATATCGCGATGTGGGACGTTATGCTGCGCGATCTGGAG
GGGCCTGACGCCACGCCGGTGTTTGAAGATCGTACCCCGCCCGAGGCCCCGACGGGCGACCTCGAGAAGGCCGATATCCT
GCGCGCGGAATGGAGTAAGATGACCGACACGCATCAATTCATGCGTCTGACATCAAAGCTGAAGATGAACCGCCTGGGTG
CCTACCGCATCGCGGGTGCCCCCCATGTCGTGGCGCTGGCCCCGTCAGCCATGACCGCAGCCCTTGAGGCGATGGCCGAG
GGCGGCGTGCCGATCATGATGTTCGTGGGCAATCGCGGCTGCATCCAGATCCACTCCGGTCCGATCCACAAGCTGGTGCC
GATGGGGCCATGGCAAAACGTGATGGACCCCGGCTTCAACCTGCATCTGCGCGCCGATCACGTGGCGGAGGTCTGGCTGG
TCAACAAACCGACAAAGCGCGGCCCCGCAATATCCGTCGAGGCGTTCGATGCCCGTGGTGCGCTGATCCTGCAATGCTTC
GCCTACCGCAAAGAGGGGCAGGGGGACAATGTCGCAAACTTCCGCGCACTTACCGAAACCCTTCCACGCCTGGCCCAATC
GGAGGAAGTGGCATGA

Upstream 100 bases:

>100_bases
GCCAAGTTGCCGCAGTTGCAAATGTGCCAGCCCCGGCCTCCGATGCGGAGGTGTGAGCAAGCCTCTTTTCCGTTCACATT
CAACGATATGAGGCGCAGAC

Downstream 100 bases:

>100_bases
GCCTCGGTTCCCGCTTTTCCCTCAGACGCCTTACGCCCGGCGGCCTTGCCCTGATCATGGCGTTTGGCCTTTTCGCAGCC
TTCGTCGCGGGCCCCGCGCG

Product: hemin-degrading

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MGADTLLSATGIRAAIADNPKTRPRDLADTLGVPEAALLAAQIGYGGVPMVADTTKLIPAICTLGEVMALTRNDSAVHEK
IGVYDNFHPGDHASSVLTADIDLRLFSRHWVHAFAMEKEVDGTVRRSVQVFDAAGDAVHKVILRERSNIAMWDVMLRDLE
GPDATPVFEDRTPPEAPTGDLEKADILRAEWSKMTDTHQFMRLTSKLKMNRLGAYRIAGAPHVVALAPSAMTAALEAMAE
GGVPIMMFVGNRGCIQIHSGPIHKLVPMGPWQNVMDPGFNLHLRADHVAEVWLVNKPTKRGPAISVEAFDARGALILQCF
AYRKEGQGDNVANFRALTETLPRLAQSEEVA

Sequences:

>Translated_351_residues
MGADTLLSATGIRAAIADNPKTRPRDLADTLGVPEAALLAAQIGYGGVPMVADTTKLIPAICTLGEVMALTRNDSAVHEK
IGVYDNFHPGDHASSVLTADIDLRLFSRHWVHAFAMEKEVDGTVRRSVQVFDAAGDAVHKVILRERSNIAMWDVMLRDLE
GPDATPVFEDRTPPEAPTGDLEKADILRAEWSKMTDTHQFMRLTSKLKMNRLGAYRIAGAPHVVALAPSAMTAALEAMAE
GGVPIMMFVGNRGCIQIHSGPIHKLVPMGPWQNVMDPGFNLHLRADHVAEVWLVNKPTKRGPAISVEAFDARGALILQCF
AYRKEGQGDNVANFRALTETLPRLAQSEEVA
>Mature_350_residues
GADTLLSATGIRAAIADNPKTRPRDLADTLGVPEAALLAAQIGYGGVPMVADTTKLIPAICTLGEVMALTRNDSAVHEKI
GVYDNFHPGDHASSVLTADIDLRLFSRHWVHAFAMEKEVDGTVRRSVQVFDAAGDAVHKVILRERSNIAMWDVMLRDLEG
PDATPVFEDRTPPEAPTGDLEKADILRAEWSKMTDTHQFMRLTSKLKMNRLGAYRIAGAPHVVALAPSAMTAALEAMAEG
GVPIMMFVGNRGCIQIHSGPIHKLVPMGPWQNVMDPGFNLHLRADHVAEVWLVNKPTKRGPAISVEAFDARGALILQCFA
YRKEGQGDNVANFRALTETLPRLAQSEEVA

Specific function: Part of the binding-protein-dependent transport system for hemin [H]

COG id: COG3720

COG function: function code P; Putative heme degradation protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To Y.enterocolitica hemS [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007845 [H]

Pfam domain/function: PF05171 HemS [H]

EC number: NA

Molecular weight: Translated: 38123; Mature: 37992

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGADTLLSATGIRAAIADNPKTRPRDLADTLGVPEAALLAAQIGYGGVPMVADTTKLIPA
CCCCHHHHHCCCEEEECCCCCCCCHHHHHHCCCCHHHHHHHHCCCCCCCCCCCHHHHHHH
ICTLGEVMALTRNDSAVHEKIGVYDNFHPGDHASSVLTADIDLRLFSRHWVHAFAMEKEV
HHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHH
DGTVRRSVQVFDAAGDAVHKVILRERSNIAMWDVMLRDLEGPDATPVFEDRTPPEAPTGD
CHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
LEKADILRAEWSKMTDTHQFMRLTSKLKMNRLGAYRIAGAPHVVALAPSAMTAALEAMAE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEECCHHHHHHHHHHHC
GGVPIMMFVGNRGCIQIHSGPIHKLVPMGPWQNVMDPGFNLHLRADHVAEVWLVNKPTKR
CCCEEEEEECCCCEEEECCCCCCCCCCCCCCHHHCCCCCEEEEECCCEEEEEEECCCCCC
GPAISVEAFDARGALILQCFAYRKEGQGDNVANFRALTETLPRLAQSEEVA
CCEEEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GADTLLSATGIRAAIADNPKTRPRDLADTLGVPEAALLAAQIGYGGVPMVADTTKLIPA
CCCHHHHHCCCEEEECCCCCCCCHHHHHHCCCCHHHHHHHHCCCCCCCCCCCHHHHHHH
ICTLGEVMALTRNDSAVHEKIGVYDNFHPGDHASSVLTADIDLRLFSRHWVHAFAMEKEV
HHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHH
DGTVRRSVQVFDAAGDAVHKVILRERSNIAMWDVMLRDLEGPDATPVFEDRTPPEAPTGD
CHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
LEKADILRAEWSKMTDTHQFMRLTSKLKMNRLGAYRIAGAPHVVALAPSAMTAALEAMAE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEECCHHHHHHHHHHHC
GGVPIMMFVGNRGCIQIHSGPIHKLVPMGPWQNVMDPGFNLHLRADHVAEVWLVNKPTKR
CCCEEEEEECCCCEEEECCCCCCCCCCCCCCHHHCCCCCEEEEECCCEEEEEEECCCCCC
GPAISVEAFDARGALILQCFAYRKEGQGDNVANFRALTETLPRLAQSEEVA
CCEEEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9026634; 11586360; 12142430 [H]