Click here to switch to the map view.

The map label for this gene is yfhA [H]

Identifier: 89054615

GI number: 89054615

Start: 2133302

End: 2134300

Strand: Direct

Name: yfhA [H]

Synonym: Jann_2124

Alternate gene names: 89054615

Gene position: 2133302-2134300 (Clockwise)

Preceding gene: 89054614

Following gene: 89054616

Centisome position: 49.41

GC content: 66.17

Gene sequence:

>999_bases
ATGACGGCCGCGCGCATCAGTTTGCCCGTGGCGCTCATGGCGCTGGCGCTTGTGGCCGCCGCGATGGGAAGCTCCTTCAT
GCCGCTTGACCGGATCATCGCGGCGCTGTTCGGGCAGGGCAGCCGACCGGATACGGTGATCCTCTGGACCCTGCGCCTGC
CGCGGGTTCTCATGGCGATATTGGCGGGCGCGGGCCTTGGGATTGCAGGAGTTCTGCTGCAACGCGCGACGCGCAACCCG
CTGGCCTCCCCGGGCGTGTTGGGCGTGGTCGACGGTGCGGCTATCGGGGTGCTGGTGTTCCTGCTCGTGTTCTCGAACGA
GGCCAACGCGCTGGCCGTCTCTGTCGCCTGGCAACCCATCGCGGCCATCATCGGTGCGTTGATCTTCGCGGCATTTGTGG
CCGTATTGGCGTATCGGGACATCGCGCGGCCCATGACGCTGATCCTTTACGGGATCGCGCTGGCGGCGCTGGCCAACGCC
GTCGTCGTCCTTCTGATTATCGCGGGACCGGTCTACCGGGCATCACAGGGGCTTATCTGGCTGGCAGGGTCCGTCCAAAG
CGCGGAGTGGCGCGAAGTCTGGATATTGCTTGCAGCGCTGATCGGGGCCGTACCGGTGCTGGCCGCATTGATCCGCCCGC
TGGACCAAATGCACCTGGATGATCACAGCGCCCGTGCGACGGGCCTCTCGGTCAACCGGGTGCGGGTCTTCGCGCTGATC
CTGTCGGTTCTGCTGACGGCTGCCATGGTCTCCATCGTTGGTGGCGTCGGCTTTGTCGGGCTGATCGCACCGCACGCCGC
GCGGCTGCTTTTCGGCAACCGGGCTGTGTGGCAGCTGACCGGGGCTGCACTGATCGGCGCGGGCATGGTCCTTGGCGCGG
ACCTCATCGTGCGGGTTCTGTTCCAGCCATTGGAGGTCCCCGCAGGCGCCGTAACGGCCCTGATCGGCGCACCGTATTTC
CTTTTTCTCCTGATCCGACAAGGTCGCGCCCATGCTTGA

Upstream 100 bases:

>100_bases
TCGTCCTGTACCCGTCCGAGGCGCCCGTCAGCGCGGTGATGGCGCTGATCGGCGTTCCGATCCTGATCGGCCTGCTGCGC
GGCACAAGGATGCGACTGGC

Downstream 100 bases:

>100_bases
GCCGCTTATCACAATCGACGCGGGCACCATCGGCTATCGCGACGTGCCCGTGTTCCAGAACCTGACGCTCACCATCCCGA
AAGGCGAGGTCACGGCCCTT

Product: transport system permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MTAARISLPVALMALALVAAAMGSSFMPLDRIIAALFGQGSRPDTVILWTLRLPRVLMAILAGAGLGIAGVLLQRATRNP
LASPGVLGVVDGAAIGVLVFLLVFSNEANALAVSVAWQPIAAIIGALIFAAFVAVLAYRDIARPMTLILYGIALAALANA
VVVLLIIAGPVYRASQGLIWLAGSVQSAEWREVWILLAALIGAVPVLAALIRPLDQMHLDDHSARATGLSVNRVRVFALI
LSVLLTAAMVSIVGGVGFVGLIAPHAARLLFGNRAVWQLTGAALIGAGMVLGADLIVRVLFQPLEVPAGAVTALIGAPYF
LFLLIRQGRAHA

Sequences:

>Translated_332_residues
MTAARISLPVALMALALVAAAMGSSFMPLDRIIAALFGQGSRPDTVILWTLRLPRVLMAILAGAGLGIAGVLLQRATRNP
LASPGVLGVVDGAAIGVLVFLLVFSNEANALAVSVAWQPIAAIIGALIFAAFVAVLAYRDIARPMTLILYGIALAALANA
VVVLLIIAGPVYRASQGLIWLAGSVQSAEWREVWILLAALIGAVPVLAALIRPLDQMHLDDHSARATGLSVNRVRVFALI
LSVLLTAAMVSIVGGVGFVGLIAPHAARLLFGNRAVWQLTGAALIGAGMVLGADLIVRVLFQPLEVPAGAVTALIGAPYF
LFLLIRQGRAHA
>Mature_331_residues
TAARISLPVALMALALVAAAMGSSFMPLDRIIAALFGQGSRPDTVILWTLRLPRVLMAILAGAGLGIAGVLLQRATRNPL
ASPGVLGVVDGAAIGVLVFLLVFSNEANALAVSVAWQPIAAIIGALIFAAFVAVLAYRDIARPMTLILYGIALAALANAV
VVLLIIAGPVYRASQGLIWLAGSVQSAEWREVWILLAALIGAVPVLAALIRPLDQMHLDDHSARATGLSVNRVRVFALIL
SVLLTAAMVSIVGGVGFVGLIAPHAARLLFGNRAVWQLTGAALIGAGMVLGADLIVRVLFQPLEVPAGAVTALIGAPYFL
FLLIRQGRAHA

Specific function: Part of the ABC transporter complex yfiYZ/yfhA/yusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen (Probable) [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=322, Percent_Identity=34.7826086956522, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1786804, Length=313, Percent_Identity=36.4217252396166, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1786347, Length=281, Percent_Identity=34.1637010676157, Blast_Score=131, Evalue=8e-32,
Organism=Escherichia coli, GI1790741, Length=292, Percent_Identity=38.6986301369863, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1788004, Length=287, Percent_Identity=33.7979094076655, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786805, Length=322, Percent_Identity=33.8509316770186, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 34405; Mature: 34274

Theoretical pI: Translated: 11.76; Mature: 11.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAARISLPVALMALALVAAAMGSSFMPLDRIIAALFGQGSRPDTVILWTLRLPRVLMAI
CCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHH
LAGAGLGIAGVLLQRATRNPLASPGVLGVVDGAAIGVLVFLLVFSNEANALAVSVAWQPI
HHCCCCHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHH
AAIIGALIFAAFVAVLAYRDIARPMTLILYGIALAALANAVVVLLIIAGPVYRASQGLIW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEE
LAGSVQSAEWREVWILLAALIGAVPVLAALIRPLDQMHLDDHSARATGLSVNRVRVFALI
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCHHHHHHHHHH
LSVLLTAAMVSIVGGVGFVGLIAPHAARLLFGNRAVWQLTGAALIGAGMVLGADLIVRVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FQPLEVPAGAVTALIGAPYFLFLLIRQGRAHA
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TAARISLPVALMALALVAAAMGSSFMPLDRIIAALFGQGSRPDTVILWTLRLPRVLMAI
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHH
LAGAGLGIAGVLLQRATRNPLASPGVLGVVDGAAIGVLVFLLVFSNEANALAVSVAWQPI
HHCCCCHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHH
AAIIGALIFAAFVAVLAYRDIARPMTLILYGIALAALANAVVVLLIIAGPVYRASQGLIW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEE
LAGSVQSAEWREVWILLAALIGAVPVLAALIRPLDQMHLDDHSARATGLSVNRVRVFALI
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCHHHHHHHHHH
LSVLLTAAMVSIVGGVGFVGLIAPHAARLLFGNRAVWQLTGAALIGAGMVLGADLIVRVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FQPLEVPAGAVTALIGAPYFLFLLIRQGRAHA
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]