Click here to switch to the map view.

The map label for this gene is guaA [H]

Identifier: 89054347

GI number: 89054347

Start: 1843257

End: 1843988

Strand: Direct

Name: guaA [H]

Synonym: Jann_1856

Alternate gene names: 89054347

Gene position: 1843257-1843988 (Clockwise)

Preceding gene: 89054346

Following gene: 89054348

Centisome position: 42.69

GC content: 64.75

Gene sequence:

>732_bases
ATGAGGCCATTCCTGATCCTTCAGTTGCGCCCCGAAGACGCAGCCGCGGATGAGGAGTTCGCGGCCTTCCTCGACCGGGG
CGGTCTTGCGCCCGACGAGGTGCAGCGCGTGCGTTTGGATGAAGGGCCGATCCCCGCGCTGTCCCTGGACGACATCGCGG
GCATCATCGTCGGCGGTGGTCCGGGCTGCGTATCCGATGCGGCGGATGCAAAAGACCCGCTGGAGGCCCGGATCGAGGCC
GATATCATGGGGCTGATGCCCGAGATCCTGTCCCGCGACATGCCGTTTCTTGGCTGCTGCTACGGGATGGGCATCCTCGG
TGCGGCCCTTGGGGCACCCGTGGGCAAGGATCGCTATGGCGAGGTCATTGGTGGCGTGACCTGTGACGTGACAGATGCCG
GGGCCCGCGATCCACTGCTGGACGGCGTCCCCACTACGTTTCGCGCTTTGGTCGGCCATAAAGAGGCGGTGGAAGAGCTG
CCCGATGGCGCGGTCCACCTCGTCGCCTCCACCCCCTGTCCGTTCCAAATGATCCGCGCCGGACAAAATGTCTACGCCAC
CCAGTTCCACCCCGAAGCGCGCGGCGAAAACTTCGCCAACCGGATCGAGATCTACCGCGACCGGGGCTATTTCGCGCCAG
AAGATGCGGGGGCCTTGACCGATGCGGTTCTGGCCGAAGAGATCACGGCCCCGGAACGCATCCTGCACAATTTCGTGACG
CGATTTCGGTAA

Upstream 100 bases:

>100_bases
AGGGCTGGCGCGTCGTACAGCGCCAGGAGGTGGAGCGGTGCGGGGTAAAAATCCCCAACGCCCGCATGGAAAAGCGCCTG
ATCCGCCGGTTTGCCGCCGC

Downstream 100 bases:

>100_bases
GTCATTGATTTATCATCTGTAACCCTTGGCCTACATAACCCCCTGGACAAATCTTTCCTTGGGTTTCCCGGCCGCCGCTC
CATATGATTAAATACATCAT

Product: glutamine amidotransferase

Products: NA

Alternate protein names: GMP synthetase; Glutamine amidotransferase [H]

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MRPFLILQLRPEDAAADEEFAAFLDRGGLAPDEVQRVRLDEGPIPALSLDDIAGIIVGGGPGCVSDAADAKDPLEARIEA
DIMGLMPEILSRDMPFLGCCYGMGILGAALGAPVGKDRYGEVIGGVTCDVTDAGARDPLLDGVPTTFRALVGHKEAVEEL
PDGAVHLVASTPCPFQMIRAGQNVYATQFHPEARGENFANRIEIYRDRGYFAPEDAGALTDAVLAEEITAPERILHNFVT
RFR

Sequences:

>Translated_243_residues
MRPFLILQLRPEDAAADEEFAAFLDRGGLAPDEVQRVRLDEGPIPALSLDDIAGIIVGGGPGCVSDAADAKDPLEARIEA
DIMGLMPEILSRDMPFLGCCYGMGILGAALGAPVGKDRYGEVIGGVTCDVTDAGARDPLLDGVPTTFRALVGHKEAVEEL
PDGAVHLVASTPCPFQMIRAGQNVYATQFHPEARGENFANRIEIYRDRGYFAPEDAGALTDAVLAEEITAPERILHNFVT
RFR
>Mature_243_residues
MRPFLILQLRPEDAAADEEFAAFLDRGGLAPDEVQRVRLDEGPIPALSLDDIAGIIVGGGPGCVSDAADAKDPLEARIEA
DIMGLMPEILSRDMPFLGCCYGMGILGAALGAPVGKDRYGEVIGGVTCDVTDAGARDPLLDGVPTTFRALVGHKEAVEEL
PDGAVHLVASTPCPFQMIRAGQNVYATQFHPEARGENFANRIEIYRDRGYFAPEDAGALTDAVLAEEITAPERILHNFVT
RFR

Specific function: Catalyzes the synthesis of GMP from XMP [H]

COG id: COG0518

COG function: function code F; GMP synthase - Glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GMP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR001674
- InterPro:   IPR004739
- InterPro:   IPR022955
- InterPro:   IPR022310
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00117 GATase; PF00958 GMP_synt_C; PF02540 NAD_synthase [H]

EC number: =6.3.5.2 [H]

Molecular weight: Translated: 26005; Mature: 26005

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPFLILQLRPEDAAADEEFAAFLDRGGLAPDEVQRVRLDEGPIPALSLDDIAGIIVGGG
CCCEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCEECCCCCEEEECCC
PGCVSDAADAKDPLEARIEADIMGLMPEILSRDMPFLGCCYGMGILGAALGAPVGKDRYG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHH
EVIGGVTCDVTDAGARDPLLDGVPTTFRALVGHKEAVEELPDGAVHLVASTPCPFQMIRA
HHHCCEEECCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHCCCCEEEEEECCCCCHHHHHC
GQNVYATQFHPEARGENFANRIEIYRDRGYFAPEDAGALTDAVLAEEITAPERILHNFVT
CCCEEEEECCCHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHH
RFR
HCC
>Mature Secondary Structure
MRPFLILQLRPEDAAADEEFAAFLDRGGLAPDEVQRVRLDEGPIPALSLDDIAGIIVGGG
CCCEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCEECCCCCEEEECCC
PGCVSDAADAKDPLEARIEADIMGLMPEILSRDMPFLGCCYGMGILGAALGAPVGKDRYG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHH
EVIGGVTCDVTDAGARDPLLDGVPTTFRALVGHKEAVEELPDGAVHLVASTPCPFQMIRA
HHHCCEEECCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHCCCCEEEEEECCCCCHHHHHC
GQNVYATQFHPEARGENFANRIEIYRDRGYFAPEDAGALTDAVLAEEITAPERILHNFVT
CCCEEEEECCCHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHH
RFR
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA