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The map label for this gene is ycfF [C]

Identifier: 89054170

GI number: 89054170

Start: 1663954

End: 1664328

Strand: Direct

Name: ycfF [C]

Synonym: Jann_1679

Alternate gene names: 89054170

Gene position: 1663954-1664328 (Clockwise)

Preceding gene: 89054169

Following gene: 89054171

Centisome position: 38.54

GC content: 62.4

Gene sequence:

>375_bases
ATGGCATTTGACTACGACGACCAGAATATTTTCGCGAAGATCCTGCGCGGCGAGATCCCCAACACGACGTTGGCCGAGAC
CGCGCATACCCTGGCATTTGCGGATCTGTACCCGCAGGCACCGGTCCATGTGCTGGTGATCCCCAAGGGGCCTTACGTCT
GCTTTGATCACTTCGCGGCAGAGGCGTCAGACGCGGAAATCGCGGATTTTCACCGGGTGGCCGCGCAGGTCTGTGCCGAA
ATATCCCCGGGCGCGGGCGGGGCGGGGTATCGCACCATCTCCAACGCGGGCGAAGACGGCGTGCAGGACGTGCCGCATTA
TCACATGCATATCCTCGCCGGACGCCCCCTGGGACGGATGCTGGCAAAAGCCTGA

Upstream 100 bases:

>100_bases
GAGAATGCCGCCGTTCTGGCGGAGTTTTTCGGGATAGATCACGATAGGGGCAAGGAGCTGGCCGAAACCCAGCACCTGTT
CGCGGATTAAGGGGCTGACC

Downstream 100 bases:

>100_bases
CGGGGAGGGGTGCGCGCGTCCTCAAGCCCATGCCCCAAGGGGCAAGAGCCCTCGGCCACCCGCGCTGCCGCGGAGATGGG
GCAGGGGGCGGGTGTGTATA

Product: histidine triad (HIT) protein

Products: ADP

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 124; Mature: 123

Protein sequence:

>124_residues
MAFDYDDQNIFAKILRGEIPNTTLAETAHTLAFADLYPQAPVHVLVIPKGPYVCFDHFAAEASDAEIADFHRVAAQVCAE
ISPGAGGAGYRTISNAGEDGVQDVPHYHMHILAGRPLGRMLAKA

Sequences:

>Translated_124_residues
MAFDYDDQNIFAKILRGEIPNTTLAETAHTLAFADLYPQAPVHVLVIPKGPYVCFDHFAAEASDAEIADFHRVAAQVCAE
ISPGAGGAGYRTISNAGEDGVQDVPHYHMHILAGRPLGRMLAKA
>Mature_123_residues
AFDYDDQNIFAKILRGEIPNTTLAETAHTLAFADLYPQAPVHVLVIPKGPYVCFDHFAAEASDAEIADFHRVAAQVCAEI
SPGAGGAGYRTISNAGEDGVQDVPHYHMHILAGRPLGRMLAKA

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI4885413, Length=109, Percent_Identity=39.4495412844037, Blast_Score=74, Evalue=3e-14,
Organism=Homo sapiens, GI14211923, Length=109, Percent_Identity=39.4495412844037, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787346, Length=116, Percent_Identity=40.5172413793103, Blast_Score=74, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17506713, Length=111, Percent_Identity=38.7387387387387, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28574010, Length=113, Percent_Identity=38.9380530973451, Blast_Score=73, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24581222, Length=112, Percent_Identity=39.2857142857143, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: 3.6.1.41

Molecular weight: Translated: 13318; Mature: 13187

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFDYDDQNIFAKILRGEIPNTTLAETAHTLAFADLYPQAPVHVLVIPKGPYVCFDHFAA
CCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEHHHHHC
EASDAEIADFHRVAAQVCAEISPGAGGAGYRTISNAGEDGVQDVPHYHMHILAGRPLGRM
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHH
LAKA
HHCC
>Mature Secondary Structure 
AFDYDDQNIFAKILRGEIPNTTLAETAHTLAFADLYPQAPVHVLVIPKGPYVCFDHFAA
CCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEHHHHHC
EASDAEIADFHRVAAQVCAEISPGAGGAGYRTISNAGEDGVQDVPHYHMHILAGRPLGRM
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHH
LAKA
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: P1,P4-bis(5'-adenosyl) tetraphosphate; H2O

Specific reaction: P1,P4-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2664449; 1472710 [H]