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The map label for this gene is cya1 [H]

Identifier: 89054165

GI number: 89054165

Start: 1656922

End: 1659117

Strand: Direct

Name: cya1 [H]

Synonym: Jann_1674

Alternate gene names: 89054165

Gene position: 1656922-1659117 (Clockwise)

Preceding gene: 89054163

Following gene: 89054169

Centisome position: 38.37

GC content: 66.35

Gene sequence:

>2196_bases
ATGGCCCGGCTGACCTTCGCGCTGGGGCTGTTGGTCACGGTGGCGATGGTGGTGCTGACGGCATTTCCGCCCCCGATCCT
TGATCGCGCCCGCGATGCGGTGTTCGACGGCTACCAACGCTCGGCCCCGCGCGCCTACGACCCCGACGCGCCCGTGCACA
TCATCGATATCGACGAGGCCGCGCTGGAGACCTATGGCCAATGGCCCTGGCCGCGCAGCTACATGGCCGAAATGACGGAT
CGATTGTTTGACCATGGCGCGGCTGCCGTGGGGTTCGATGTGCTCTTCCCGGAGCCGGACCGGACGTCGCCTGACCTGAT
CGTCGAATCCTGGACCCGCTTTGCCGACGCCCCCGCGCCGGTCCTGCCGGATCTTGGGATTGCGCCCCATGACAGCCGGT
TCGCGCAATCCATGCAGGGCCGCGCCGTGGTCCTGTCAGTGGCGGGCGGGTTGGAGGGCACCATGCCCGAGGCGGTGGCG
GGCTTTGCCGTAACAGGCGCCACCCCCACAACGCTGACCACCTATCCCGGCGCGATCAGCAATCTGGAGGAGTTGACAGC
AGCGGCCAGCGGCATTGGTACGATCAGCCTTGGACGCAATGCGGACGGGATCACGCGGACGGTGCCCATGGTCTCTGAGT
TCGGGGGCGTGCTGATCCCATCGCTCTCGGCAGAGCTGTTGCGCGTGGCGCAGGGGGCGGGGGGGCATATCCTCAAGACG
ACGGAGGCTTCGGGCGAGGTCTCGGGCGGGACGGTCGCTGCCACGGCGATGCAAACCGGCGCCCTGGCGTTCCCGCTGGA
GGCCGATGGCCGCTTTCGTCTGTATTATGCGGGCTACCAGCCCGAGCGTGTGACGCCCGCCGGCGAGTTGTTCGACGCCG
ATGGCATCGACCCGGCCTTGCAACAGCGGCTGGCGGGACGGATCATTCTGGTGGGATCCTCGGCGCAGGGGTTGTTTGAC
ATCCGTACGACGCCGTTGGACGGGCAAATCGCGGGCGTCACCCTTCACGCGGAAATCATTGAACAAATCGTTACGGGCAG
CTTCCTGTCCCGGCCCGATTGGATGCGGGGACTGGAGATCTTGATCGTGGCGCTTACGGGTCTGGCGCTGACGATCCTCA
ATCGGATGGAGCGGCCGCTTCTGGGCCTGTCTGCGGCGCTGGCCTTCGGCGGCGGGTCCGTTGTGGGGGGCATTCTGGCC
TTCACGTCCTTGGGCATGTTGTTCAGTCCGGTGATGACGGTGCTGACCGCAACGCTGGTCTATCTGCCGGGCACGACGCT
GGGATATCTGGCCAAGGAACGCGCGCGCCGATCGATCCGGGAACGCTTCGCCCGCTTCCTGCCGCCGCCGCTGATTGCCG
AGATCGAGAAGAACCCCGCCGCCGCGCTGACCCCCGAGGGGGCGGAGCGGGATCTGACGGTGATGTTCGTGGATATGCGC
GGGTTTTCCACGGTGACGGAAGGGATGCCGCCGGACCGGGTGGTGACGTTGGTCAACACCTTCCTGTCTGCGGTGGCCGA
GGCGCTTGTGGACCACGGCGCGACCATCGACAAGTTCATGGGCGATGCGGTCATGGCGTTCTGGAATGCGCCGATTGAAC
GCGATGACCACGCCGTTGCCGCCCTGGGCGCGCTGCACGCGATCAACGACGCCGCAGAACAGGCGAATTTCCTGCTGACG
TCCCAGGGTTTGCCGCGCGTGACGCTGGGGGTGGGGCTGAATACCGGGCCTGCGTCGGTGGGTTTGATGGGGTCCCGGGA
CCGGCTGTCCTATACCTGCATCGGCGATAGCGTGACGCTGGCCGCGCGGCTGGAGGGGCTGACGCGGATCTATGGCACAC
GGAACTGCGTGGGTCCCAATACTGTGGCGCAGTGTCCGGCGCATCTTCAGGCCGTGACGCTGGACCTGATCGCCGTGAAG
GGGTTCGCCCGCGCCGTGGAGGTGTCCACCGTCCTGCCGCGCGCAACCCCGGGGCTGGAGGAGTTTTCAGCAGCACTGGC
ACTGGCCCGGACCATCTTCGTGGCCCGCGATTGGGACGGGGCGGAAGCGGCAATGATGCAGGTGGCGAAGATCAAGGTCC
CCACATGCAACACCGGCCTTCTGGCGCAGCTCTACCTCGACCGGATCGCCGCCTATAAAGAAATCCCCCCGCCAGAGGGC
TGGCAGGGGGAATTCGTCGCCTTGTCAAAAAGATAG

Upstream 100 bases:

>100_bases
GGAAGGGTTTGCGACGACACGAAAAATCCGCCACGATCAACGGTATGAGACAGGGGATTAACGTGGCACCAGATGCAATC
CGCGCGGCAAGGGGCACCCG

Downstream 100 bases:

>100_bases
ATCCTTACGGGAAAGTCGGCGTTCCGAAACACCCCGGCGCCGGGTCCTGGGGGTCGCAATTGGTCGGCGTCGTCGGCATA
GGATCCATAACTGCATCGTC

Product: adenylate/guanylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 1; Adenylyl cyclase 1 [H]

Number of amino acids: Translated: 731; Mature: 730

Protein sequence:

>731_residues
MARLTFALGLLVTVAMVVLTAFPPPILDRARDAVFDGYQRSAPRAYDPDAPVHIIDIDEAALETYGQWPWPRSYMAEMTD
RLFDHGAAAVGFDVLFPEPDRTSPDLIVESWTRFADAPAPVLPDLGIAPHDSRFAQSMQGRAVVLSVAGGLEGTMPEAVA
GFAVTGATPTTLTTYPGAISNLEELTAAASGIGTISLGRNADGITRTVPMVSEFGGVLIPSLSAELLRVAQGAGGHILKT
TEASGEVSGGTVAATAMQTGALAFPLEADGRFRLYYAGYQPERVTPAGELFDADGIDPALQQRLAGRIILVGSSAQGLFD
IRTTPLDGQIAGVTLHAEIIEQIVTGSFLSRPDWMRGLEILIVALTGLALTILNRMERPLLGLSAALAFGGGSVVGGILA
FTSLGMLFSPVMTVLTATLVYLPGTTLGYLAKERARRSIRERFARFLPPPLIAEIEKNPAAALTPEGAERDLTVMFVDMR
GFSTVTEGMPPDRVVTLVNTFLSAVAEALVDHGATIDKFMGDAVMAFWNAPIERDDHAVAALGALHAINDAAEQANFLLT
SQGLPRVTLGVGLNTGPASVGLMGSRDRLSYTCIGDSVTLAARLEGLTRIYGTRNCVGPNTVAQCPAHLQAVTLDLIAVK
GFARAVEVSTVLPRATPGLEEFSAALALARTIFVARDWDGAEAAMMQVAKIKVPTCNTGLLAQLYLDRIAAYKEIPPPEG
WQGEFVALSKR

Sequences:

>Translated_731_residues
MARLTFALGLLVTVAMVVLTAFPPPILDRARDAVFDGYQRSAPRAYDPDAPVHIIDIDEAALETYGQWPWPRSYMAEMTD
RLFDHGAAAVGFDVLFPEPDRTSPDLIVESWTRFADAPAPVLPDLGIAPHDSRFAQSMQGRAVVLSVAGGLEGTMPEAVA
GFAVTGATPTTLTTYPGAISNLEELTAAASGIGTISLGRNADGITRTVPMVSEFGGVLIPSLSAELLRVAQGAGGHILKT
TEASGEVSGGTVAATAMQTGALAFPLEADGRFRLYYAGYQPERVTPAGELFDADGIDPALQQRLAGRIILVGSSAQGLFD
IRTTPLDGQIAGVTLHAEIIEQIVTGSFLSRPDWMRGLEILIVALTGLALTILNRMERPLLGLSAALAFGGGSVVGGILA
FTSLGMLFSPVMTVLTATLVYLPGTTLGYLAKERARRSIRERFARFLPPPLIAEIEKNPAAALTPEGAERDLTVMFVDMR
GFSTVTEGMPPDRVVTLVNTFLSAVAEALVDHGATIDKFMGDAVMAFWNAPIERDDHAVAALGALHAINDAAEQANFLLT
SQGLPRVTLGVGLNTGPASVGLMGSRDRLSYTCIGDSVTLAARLEGLTRIYGTRNCVGPNTVAQCPAHLQAVTLDLIAVK
GFARAVEVSTVLPRATPGLEEFSAALALARTIFVARDWDGAEAAMMQVAKIKVPTCNTGLLAQLYLDRIAAYKEIPPPEG
WQGEFVALSKR
>Mature_730_residues
ARLTFALGLLVTVAMVVLTAFPPPILDRARDAVFDGYQRSAPRAYDPDAPVHIIDIDEAALETYGQWPWPRSYMAEMTDR
LFDHGAAAVGFDVLFPEPDRTSPDLIVESWTRFADAPAPVLPDLGIAPHDSRFAQSMQGRAVVLSVAGGLEGTMPEAVAG
FAVTGATPTTLTTYPGAISNLEELTAAASGIGTISLGRNADGITRTVPMVSEFGGVLIPSLSAELLRVAQGAGGHILKTT
EASGEVSGGTVAATAMQTGALAFPLEADGRFRLYYAGYQPERVTPAGELFDADGIDPALQQRLAGRIILVGSSAQGLFDI
RTTPLDGQIAGVTLHAEIIEQIVTGSFLSRPDWMRGLEILIVALTGLALTILNRMERPLLGLSAALAFGGGSVVGGILAF
TSLGMLFSPVMTVLTATLVYLPGTTLGYLAKERARRSIRERFARFLPPPLIAEIEKNPAAALTPEGAERDLTVMFVDMRG
FSTVTEGMPPDRVVTLVNTFLSAVAEALVDHGATIDKFMGDAVMAFWNAPIERDDHAVAALGALHAINDAAEQANFLLTS
QGLPRVTLGVGLNTGPASVGLMGSRDRLSYTCIGDSVTLAARLEGLTRIYGTRNCVGPNTVAQCPAHLQAVTLDLIAVKG
FARAVEVSTVLPRATPGLEEFSAALALARTIFVARDWDGAEAAMMQVAKIKVPTCNTGLLAQLYLDRIAAYKEIPPPEGW
QGEFVALSKR

Specific function: Plays essential roles in regulation of cellular metabolism by catalyzing the synthesis of a second messenger, cAMP [H]

COG id: COG4252

COG function: function code T; Predicted transmembrane sensor domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HAMP domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00672 HAMP [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 77320; Mature: 77189

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLTFALGLLVTVAMVVLTAFPPPILDRARDAVFDGYQRSAPRAYDPDAPVHIIDIDEA
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHCCCCCCCCCCCEEEEECCHH
ALETYGQWPWPRSYMAEMTDRLFDHGAAAVGFDVLFPEPDRTSPDLIVESWTRFADAPAP
HHHHCCCCCCCHHHHHHHHHHHHHCCCHHEEEEEECCCCCCCCHHHHHHHHHHHCCCCCC
VLPDLGIAPHDSRFAQSMQGRAVVLSVAGGLEGTMPEAVAGFAVTGATPTTLTTYPGAIS
CCCCCCCCCCCHHHHHHHCCCEEEEEECCCCCCCCHHHHHCEEEECCCCCEEEECCCHHH
NLEELTAAASGIGTISLGRNADGITRTVPMVSEFGGVLIPSLSAELLRVAQGAGGHILKT
HHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCEECCHHHHHHHHHHCCCCCCEEEE
TEASGEVSGGTVAATAMQTGALAFPLEADGRFRLYYAGYQPERVTPAGELFDADGIDPAL
CCCCCCCCCCEEEEHHHCCCCEEEEECCCCEEEEEECCCCCCCCCCCHHCCCCCCCCHHH
QQRLAGRIILVGSSAQGLFDIRTTPLDGQIAGVTLHAEIIEQIVTGSFLSRPDWMRGLEI
HHHHCCEEEEEECCCCCEEEEECCCCCCEEEEEEEHHHHHHHHHHCHHHCCCHHHHHHHH
LIVALTGLALTILNRMERPLLGLSAALAFGGGSVVGGILAFTSLGMLFSPVMTVLTATLV
HHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLPGTTLGYLAKERARRSIRERFARFLPPPLIAEIEKNPAAALTPEGAERDLTVMFVDMR
HCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEECCCCCCCCEEEEEEECC
GFSTVTEGMPPDRVVTLVNTFLSAVAEALVDHGATIDKFMGDAVMAFWNAPIERDDHAVA
CCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHH
ALGALHAINDAAEQANFLLTSQGLPRVTLGVGLNTGPASVGLMGSRDRLSYTCIGDSVTL
HHHHHHHHHHHHHHCCEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCEEH
AARLEGLTRIYGTRNCVGPNTVAQCPAHLQAVTLDLIAVKGFARAVEVSTVLPRATPGLE
HHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
EFSAALALARTIFVARDWDGAEAAMMQVAKIKVPTCNTGLLAQLYLDRIAAYKEIPPPEG
HHHHHHHHHHHHHEEECCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHCCCCCCC
WQGEFVALSKR
CCCCEEEECCC
>Mature Secondary Structure 
ARLTFALGLLVTVAMVVLTAFPPPILDRARDAVFDGYQRSAPRAYDPDAPVHIIDIDEA
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHCCCCCCCCCCCEEEEECCHH
ALETYGQWPWPRSYMAEMTDRLFDHGAAAVGFDVLFPEPDRTSPDLIVESWTRFADAPAP
HHHHCCCCCCCHHHHHHHHHHHHHCCCHHEEEEEECCCCCCCCHHHHHHHHHHHCCCCCC
VLPDLGIAPHDSRFAQSMQGRAVVLSVAGGLEGTMPEAVAGFAVTGATPTTLTTYPGAIS
CCCCCCCCCCCHHHHHHHCCCEEEEEECCCCCCCCHHHHHCEEEECCCCCEEEECCCHHH
NLEELTAAASGIGTISLGRNADGITRTVPMVSEFGGVLIPSLSAELLRVAQGAGGHILKT
HHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCEECCHHHHHHHHHHCCCCCCEEEE
TEASGEVSGGTVAATAMQTGALAFPLEADGRFRLYYAGYQPERVTPAGELFDADGIDPAL
CCCCCCCCCCEEEEHHHCCCCEEEEECCCCEEEEEECCCCCCCCCCCHHCCCCCCCCHHH
QQRLAGRIILVGSSAQGLFDIRTTPLDGQIAGVTLHAEIIEQIVTGSFLSRPDWMRGLEI
HHHHCCEEEEEECCCCCEEEEECCCCCCEEEEEEEHHHHHHHHHHCHHHCCCHHHHHHHH
LIVALTGLALTILNRMERPLLGLSAALAFGGGSVVGGILAFTSLGMLFSPVMTVLTATLV
HHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLPGTTLGYLAKERARRSIRERFARFLPPPLIAEIEKNPAAALTPEGAERDLTVMFVDMR
HCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEECCCCCCCCEEEEEEECC
GFSTVTEGMPPDRVVTLVNTFLSAVAEALVDHGATIDKFMGDAVMAFWNAPIERDDHAVA
CCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHH
ALGALHAINDAAEQANFLLTSQGLPRVTLGVGLNTGPASVGLMGSRDRLSYTCIGDSVTL
HHHHHHHHHHHHHHCCEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCEEH
AARLEGLTRIYGTRNCVGPNTVAQCPAHLQAVTLDLIAVKGFARAVEVSTVLPRATPGLE
HHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
EFSAALALARTIFVARDWDGAEAAMMQVAKIKVPTCNTGLLAQLYLDRIAAYKEIPPPEG
HHHHHHHHHHHHHEEECCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHCCCCCCC
WQGEFVALSKR
CCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11481430; 1970565 [H]