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The map label for this gene is prpC [H]

Identifier: 89054097

GI number: 89054097

Start: 1589469

End: 1590992

Strand: Direct

Name: prpC [H]

Synonym: Jann_1606

Alternate gene names: 89054097

Gene position: 1589469-1590992 (Clockwise)

Preceding gene: 89054096

Following gene: 89054098

Centisome position: 36.81

GC content: 66.27

Gene sequence:

>1524_bases
ATGAGCCCGGCCGCCCCCATCGGATACGACGTCGCGACCGCCCTCTGGCAGGGCGCGCGGCCCTATCAGGAAGATACCCT
GCTGGCCGATTTCCATGGCGGCATGGATCGGGGCTTTGCGGTTCTGGCCGATGGCATGGGCGGGCACGCGGCGGGGGATC
TGGCGTCGCGGCTGGTGGTGATTGACGCGGTCAGCCACCTGAAATTCCTGATGCACGACGGGGCGGCGCTGGAGACATCG
CTGGTGTCAGAGCTGACCTCGGCCATCGAGACAGCGAACAATGTCCTAAAGGACCGCGCGGCGGAGGATCGGCGGCTGCG
CGGGATGGGGGCGACGTTTCTGGCCACGGTGGTCTTTGAAGATCGCCTGTATTGGGCGTCGGTGGGCGACAGCCCGCTCT
ACCTCTGGCGGGAGGGGACATTGCGGCAGCTGAATGAAGATCACTCCATGGCACCGGTCATCGATCAGATGGCCCGCGCC
GGAGAGATCACGCCGGAACAGGCTGCCAGCCACCCCGACCGCAACGCGTTGACATCCGTGCTGATGGGGGAGCCGCTGAA
AGCCATGGATGTGCCCAAGACGGCAACGGTCCTGGACCCGGGGGATGTGTTGATTCAGGCCTCGGACGGGCTGCAATACC
TTGATGACAAGAAGATATCTGAGGTTGTGGCGCGGGGCGGCAACAGTCGCGAGATTGCAGATGCCCTGCTGGCGGCCCTA
CGGGATCTGGATGATCCGGTGCAGGACAATACGGCAATTCTTGTGCTGCAATTGATGGACCGCGTGGGCGAGGGCGCTGT
GTCGGCGACAGCGGGCTCGGCGACTGCCAAATCCACAGTTGGCAGCCCAAGCGCTCCAGCGGATGTCCCGTCTACCGCGA
CCGCTACAGGGGACACGCTTTCCGTCGGTGCACGACGCTGGGCTCTCCCTGCCGGTCTTTTGGCCGGTGCGGCTCTGGTC
GCGGGGTTGGTCTTCGGCCTGCCCGGCGGACCACCGGAACCGACATCCGTGGCAGAGCTTGAGACAGCGGGTGGCACAGC
CGATGCAGCGCCCGAGGCCGATCAGGCCCCAGCCCCTGCATTAGCCGATGCGCCAGTACCTGCCACCACGGCGGTGTCGT
CTGCCACGCCAACACCGGATGCTGTGCCCGAGGCTGACGTGACGCAAGTCCATGAAACCATAGGGGAAACGACGGCTCTC
GCCGAGGAGGGTCCTGAAGAGTCTGTGCCTGCCGTCGTCGGCCTGAAGCCCTCACAACCGGCAGCGACGGAGGCGGCACG
GGCCGCCAACGGGGCCACGATCCTGTTCGAGACAACCACCCCCGGCACGCCAGCCGCGCCCGGTGCCAATGCCGTGGGTC
TTGACGTCCTGCGTCCCCAGGATGCCCCGCCGCTTCCCAATCAGGACGCGGTGGAGGCGCAACCTGAAAGCCAGCGCACG
CGGATCCCAGAAAGCCCGCTACCCAAATCCCGCCCGTCCGCGACCGCCAAACCCACCACTAGCGAGGACGCGCGCAATGG
CTGA

Upstream 100 bases:

>100_bases
TGACGACGGAGCCTCTGACCCACGGCGATACCCTGCGGATCGGGGCGACATCCCTGCGGTTTGTCGCGCTCTGCGGGCCG
GATTTCGATTGGTCCGACCC

Downstream 100 bases:

>100_bases
CACGGTCGACCTGTCCATCCAGTCCGTGGCCAGCCAGGACGTGCTGCTGCCCTCCCAAACCCTGCGTCTGCCTGTCGAAG
TCGGCCGGTTCGGCGCGGAT

Product: protein serine/threonine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 507; Mature: 506

Protein sequence:

>507_residues
MSPAAPIGYDVATALWQGARPYQEDTLLADFHGGMDRGFAVLADGMGGHAAGDLASRLVVIDAVSHLKFLMHDGAALETS
LVSELTSAIETANNVLKDRAAEDRRLRGMGATFLATVVFEDRLYWASVGDSPLYLWREGTLRQLNEDHSMAPVIDQMARA
GEITPEQAASHPDRNALTSVLMGEPLKAMDVPKTATVLDPGDVLIQASDGLQYLDDKKISEVVARGGNSREIADALLAAL
RDLDDPVQDNTAILVLQLMDRVGEGAVSATAGSATAKSTVGSPSAPADVPSTATATGDTLSVGARRWALPAGLLAGAALV
AGLVFGLPGGPPEPTSVAELETAGGTADAAPEADQAPAPALADAPVPATTAVSSATPTPDAVPEADVTQVHETIGETTAL
AEEGPEESVPAVVGLKPSQPAATEAARAANGATILFETTTPGTPAAPGANAVGLDVLRPQDAPPLPNQDAVEAQPESQRT
RIPESPLPKSRPSATAKPTTSEDARNG

Sequences:

>Translated_507_residues
MSPAAPIGYDVATALWQGARPYQEDTLLADFHGGMDRGFAVLADGMGGHAAGDLASRLVVIDAVSHLKFLMHDGAALETS
LVSELTSAIETANNVLKDRAAEDRRLRGMGATFLATVVFEDRLYWASVGDSPLYLWREGTLRQLNEDHSMAPVIDQMARA
GEITPEQAASHPDRNALTSVLMGEPLKAMDVPKTATVLDPGDVLIQASDGLQYLDDKKISEVVARGGNSREIADALLAAL
RDLDDPVQDNTAILVLQLMDRVGEGAVSATAGSATAKSTVGSPSAPADVPSTATATGDTLSVGARRWALPAGLLAGAALV
AGLVFGLPGGPPEPTSVAELETAGGTADAAPEADQAPAPALADAPVPATTAVSSATPTPDAVPEADVTQVHETIGETTAL
AEEGPEESVPAVVGLKPSQPAATEAARAANGATILFETTTPGTPAAPGANAVGLDVLRPQDAPPLPNQDAVEAQPESQRT
RIPESPLPKSRPSATAKPTTSEDARNG
>Mature_506_residues
SPAAPIGYDVATALWQGARPYQEDTLLADFHGGMDRGFAVLADGMGGHAAGDLASRLVVIDAVSHLKFLMHDGAALETSL
VSELTSAIETANNVLKDRAAEDRRLRGMGATFLATVVFEDRLYWASVGDSPLYLWREGTLRQLNEDHSMAPVIDQMARAG
EITPEQAASHPDRNALTSVLMGEPLKAMDVPKTATVLDPGDVLIQASDGLQYLDDKKISEVVARGGNSREIADALLAALR
DLDDPVQDNTAILVLQLMDRVGEGAVSATAGSATAKSTVGSPSAPADVPSTATATGDTLSVGARRWALPAGLLAGAALVA
GLVFGLPGGPPEPTSVAELETAGGTADAAPEADQAPAPALADAPVPATTAVSSATPTPDAVPEADVTQVHETIGETTALA
EEGPEESVPAVVGLKPSQPAATEAARAANGATILFETTTPGTPAAPGANAVGLDVLRPQDAPPLPNQDAVEAQPESQRTR
IPESPLPKSRPSATAKPTTSEDARNG

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 51917; Mature: 51786

Theoretical pI: Translated: 4.16; Mature: 4.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPAAPIGYDVATALWQGARPYQEDTLLADFHGGMDRGFAVLADGMGGHAAGDLASRLVV
CCCCCCCCHHHHHHHHHCCCCCCCCCEEEHHCCCCCCCEEEEECCCCCCHHHHHHHHHHH
IDAVSHLKFLMHDGAALETSLVSELTSAIETANNVLKDRAAEDRRLRGMGATFLATVVFE
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
DRLYWASVGDSPLYLWREGTLRQLNEDHSMAPVIDQMARAGEITPEQAASHPDRNALTSV
CCEEEEECCCCCEEEECCCHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHH
LMGEPLKAMDVPKTATVLDPGDVLIQASDGLQYLDDKKISEVVARGGNSREIADALLAAL
HHCCCHHHHCCCCCEEEECCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
RDLDDPVQDNTAILVLQLMDRVGEGAVSATAGSATAKSTVGSPSAPADVPSTATATGDTL
HHCCCCCCCCHHHHHHHHHHHHCCCCEECCCCCCHHHHCCCCCCCCCCCCCCCCCCCCHH
SVGARRWALPAGLLAGAALVAGLVFGLPGGPPEPTSVAELETAGGTADAAPEADQAPAPA
HHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCC
LADAPVPATTAVSSATPTPDAVPEADVTQVHETIGETTALAEEGPEESVPAVVGLKPSQP
CCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCC
AATEAARAANGATILFETTTPGTPAAPGANAVGLDVLRPQDAPPLPNQDAVEAQPESQRT
HHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHC
RIPESPLPKSRPSATAKPTTSEDARNG
CCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SPAAPIGYDVATALWQGARPYQEDTLLADFHGGMDRGFAVLADGMGGHAAGDLASRLVV
CCCCCCCHHHHHHHHHCCCCCCCCCEEEHHCCCCCCCEEEEECCCCCCHHHHHHHHHHH
IDAVSHLKFLMHDGAALETSLVSELTSAIETANNVLKDRAAEDRRLRGMGATFLATVVFE
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
DRLYWASVGDSPLYLWREGTLRQLNEDHSMAPVIDQMARAGEITPEQAASHPDRNALTSV
CCEEEEECCCCCEEEECCCHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHH
LMGEPLKAMDVPKTATVLDPGDVLIQASDGLQYLDDKKISEVVARGGNSREIADALLAAL
HHCCCHHHHCCCCCEEEECCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
RDLDDPVQDNTAILVLQLMDRVGEGAVSATAGSATAKSTVGSPSAPADVPSTATATGDTL
HHCCCCCCCCHHHHHHHHHHHHCCCCEECCCCCCHHHHCCCCCCCCCCCCCCCCCCCCHH
SVGARRWALPAGLLAGAALVAGLVFGLPGGPPEPTSVAELETAGGTADAAPEADQAPAPA
HHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCC
LADAPVPATTAVSSATPTPDAVPEADVTQVHETIGETTALAEEGPEESVPAVVGLKPSQP
CCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCC
AATEAARAANGATILFETTTPGTPAAPGANAVGLDVLRPQDAPPLPNQDAVEAQPESQRT
HHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHC
RIPESPLPKSRPSATAKPTTSEDARNG
CCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]