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The map label for this gene is oxyR [H]

Identifier: 89054076

GI number: 89054076

Start: 1566395

End: 1567315

Strand: Reverse

Name: oxyR [H]

Synonym: Jann_1585

Alternate gene names: 89054076

Gene position: 1567315-1566395 (Counterclockwise)

Preceding gene: 89054078

Following gene: 89054068

Centisome position: 36.3

GC content: 65.04

Gene sequence:

>921_bases
ATGAATAATCTCACGATCAAACAATTGCGCTACGTCGATGCCTTGGCCCGCCACGGGCATTTCGGCCATGCGGCGGCGGC
GTGCAATGTGACGCAACCGGCCTTGTCGATGCAGATCAAGGAGATGGAGGAGGCGTTCGGCCTGCCGCTGTTTGAGCGCA
CGCCCCGGCAAGTGCGCCTGACCGGGTTCGGCGAGACTGTGCTGACCCGCGCCAAAGACATCCTACGCGCGGTTGATGAG
TTGGACGATCTGGCCCGCGCTGCCCGTGGCGGGCTGACGGGGCGGCTGCGGTTGGGCGTGATCCCGACCATCGCGCCCTA
CCTGTTGCCGCGCCTCATCGGCACTCTGGGGCTGCATTACCCGCAGATCGACCTGCATATTCGGGAAACTTTGACGCCGC
GCCTGTTGGAGGATTTGTCCGCCGGGCGGCTGGACACCGCGATCCTGGCCCTTCCCGTGTCCGTGCCCGCGTTGACCGAG
GTGCCGCTCCATGATGAGGAATTCGTCCTGGTGCGGCCCGCCGAGGATGACGACAAGCCCGTTCCCGATGGCGAGGCGCT
GGCCCAGATGCGCTTGCTTCTGCTGGAGGAAGGGCATTGCTTCCGCGACCAAGCGCTGAGTTTTTGCAACATTCGCAGCA
GCTTACCGAGAGAGGGGCTCGACGGCTCCAGCCTGTCGACATTGGTGCAAATGGTCGGCGCAGGCATTGGCGTGACGCTG
ATCCCCGATATGGCGGTGGGGGTAGAGACGCGGTCCGCCACCGTCTCCGTGGCGCGATTTGCGCAGGCGACCCCCAAACG
GACCATCGGCATGGTCTGGCGCAAAGCCAGCCCTTTGGCGACTGAGCTGGAAGGCATGGCGGAGGTCGTCCGCACAGCCA
TAATGCCGGAGGGCCTCTGCGTGGGCCCGACGCCCGGGTAA

Upstream 100 bases:

>100_bases
CTGCGACGGCAGAAGGGCCGAGTCGCGATTGGACGTAGGATAGCAGAGCCGAGCGATTAGCTACAGTTGGATATTCTGAT
AGCCGTGATAAGGTGGTCTT

Downstream 100 bases:

>100_bases
GACGGACCGATATGCGCAAATGAAACGGCCCCGCCAGTGACGGCAGGGCCAAACATCAGACGAAGGCGATGCGCCTAGTT
GGTGATCCGGAAGTGCCGCA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Morphology and auto-aggregation control protein [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MNNLTIKQLRYVDALARHGHFGHAAAACNVTQPALSMQIKEMEEAFGLPLFERTPRQVRLTGFGETVLTRAKDILRAVDE
LDDLARAARGGLTGRLRLGVIPTIAPYLLPRLIGTLGLHYPQIDLHIRETLTPRLLEDLSAGRLDTAILALPVSVPALTE
VPLHDEEFVLVRPAEDDDKPVPDGEALAQMRLLLLEEGHCFRDQALSFCNIRSSLPREGLDGSSLSTLVQMVGAGIGVTL
IPDMAVGVETRSATVSVARFAQATPKRTIGMVWRKASPLATELEGMAEVVRTAIMPEGLCVGPTPG

Sequences:

>Translated_306_residues
MNNLTIKQLRYVDALARHGHFGHAAAACNVTQPALSMQIKEMEEAFGLPLFERTPRQVRLTGFGETVLTRAKDILRAVDE
LDDLARAARGGLTGRLRLGVIPTIAPYLLPRLIGTLGLHYPQIDLHIRETLTPRLLEDLSAGRLDTAILALPVSVPALTE
VPLHDEEFVLVRPAEDDDKPVPDGEALAQMRLLLLEEGHCFRDQALSFCNIRSSLPREGLDGSSLSTLVQMVGAGIGVTL
IPDMAVGVETRSATVSVARFAQATPKRTIGMVWRKASPLATELEGMAEVVRTAIMPEGLCVGPTPG
>Mature_306_residues
MNNLTIKQLRYVDALARHGHFGHAAAACNVTQPALSMQIKEMEEAFGLPLFERTPRQVRLTGFGETVLTRAKDILRAVDE
LDDLARAARGGLTGRLRLGVIPTIAPYLLPRLIGTLGLHYPQIDLHIRETLTPRLLEDLSAGRLDTAILALPVSVPALTE
VPLHDEEFVLVRPAEDDDKPVPDGEALAQMRLLLLEEGHCFRDQALSFCNIRSSLPREGLDGSSLSTLVQMVGAGIGVTL
IPDMAVGVETRSATVSVARFAQATPKRTIGMVWRKASPLATELEGMAEVVRTAIMPEGLCVGPTPG

Specific function: Hydrogen peroxide sensor. Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS (a regulatory RNA), dps, fur and grxA. OxyR expression is negatively autoregulated by binding to a 43 bp region upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=293, Percent_Identity=40.2730375426621, Blast_Score=205, Evalue=3e-54,
Organism=Escherichia coli, GI157672245, Length=281, Percent_Identity=30.6049822064057, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI145693105, Length=286, Percent_Identity=29.7202797202797, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788887, Length=283, Percent_Identity=27.5618374558304, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787879, Length=259, Percent_Identity=32.046332046332, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788748, Length=298, Percent_Identity=29.1946308724832, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI2367136, Length=244, Percent_Identity=30.7377049180328, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788297, Length=246, Percent_Identity=26.8292682926829, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787806, Length=276, Percent_Identity=23.1884057971014, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787601, Length=146, Percent_Identity=31.5068493150685, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787530, Length=252, Percent_Identity=25, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87081904, Length=143, Percent_Identity=32.1678321678322, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1789173, Length=164, Percent_Identity=35.3658536585366, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787949, Length=148, Percent_Identity=28.3783783783784, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI145693193, Length=108, Percent_Identity=39.8148148148148, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790208, Length=251, Percent_Identity=26.2948207171315, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1788626, Length=247, Percent_Identity=30.3643724696356, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33114; Mature: 33114

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNLTIKQLRYVDALARHGHFGHAAAACNVTQPALSMQIKEMEEAFGLPLFERTPRQVRL
CCCCHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCHHHCCCCEEEE
TGFGETVLTRAKDILRAVDELDDLARAARGGLTGRLRLGVIPTIAPYLLPRLIGTLGLHY
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHCCCC
PQIDLHIRETLTPRLLEDLSAGRLDTAILALPVSVPALTEVPLHDEEFVLVRPAEDDDKP
CCEEEEHHHHCCHHHHHHHCCCCHHHHHEEECCCCCCCCCCCCCCCCEEEEECCCCCCCC
VPDGEALAQMRLLLLEEGHCFRDQALSFCNIRSSLPREGLDGSSLSTLVQMVGAGIGVTL
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEE
IPDMAVGVETRSATVSVARFAQATPKRTIGMVWRKASPLATELEGMAEVVRTAIMPEGLC
CCCHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEE
VGPTPG
CCCCCC
>Mature Secondary Structure
MNNLTIKQLRYVDALARHGHFGHAAAACNVTQPALSMQIKEMEEAFGLPLFERTPRQVRL
CCCCHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCHHHCCCCEEEE
TGFGETVLTRAKDILRAVDELDDLARAARGGLTGRLRLGVIPTIAPYLLPRLIGTLGLHY
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHCCCC
PQIDLHIRETLTPRLLEDLSAGRLDTAILALPVSVPALTEVPLHDEEFVLVRPAEDDDKP
CCEEEEHHHHCCHHHHHHHCCCCHHHHHEEECCCCCCCCCCCCCCCCEEEEECCCCCCCC
VPDGEALAQMRLLLLEEGHCFRDQALSFCNIRSSLPREGLDGSSLSTLVQMVGAGIGVTL
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEE
IPDMAVGVETRSATVSVARFAQATPKRTIGMVWRKASPLATELEGMAEVVRTAIMPEGLC
CCCHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEE
VGPTPG
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]