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The map label for this gene is aprA [H]

Identifier: 89054048

GI number: 89054048

Start: 1528191

End: 1530236

Strand: Direct

Name: aprA [H]

Synonym: Jann_1557

Alternate gene names: 89054048

Gene position: 1528191-1530236 (Clockwise)

Preceding gene: 89054045

Following gene: 89054052

Centisome position: 35.39

GC content: 57.33

Gene sequence:

>2046_bases
ATGTCCATCGGCAATCTCAACGGCACCATAGTGCCACTTACAGGCGACGATCTTATCGATGGTCTCGCTAGCGATTTTAA
ATGGCAGCTTGACGCGACGCGGACGATAGACTGGACGCTTTCCGACGGGTTAAGTGGTGAAACCTGGTACAATCCGGGTG
AGTTTATACCGCTTTTTGCAGGTTTATTCGACGGCATCGAGCCATTCATCGACGTCGACTTTAGATACGTTGGCTATCAT
TCCCATCCAGATGTCGCCATCGCACAAGGGTCCGACATCAATCTGACCTGGGACGATGCCAATGCGCTCTTTTCCAGCCC
CAATACCTGGGCTCTGGCGTTTTTCCCGCAGCCAGGTTCTTTGCCCCGTGGAGAGATCTACTTCAATTCAAGAAGTGATC
TAAACTATCAATCATCGTATGCGCCTGGTAGCCAAGGTTTTTTTGTTCCCTTGCACGAGGTTGGCCATGCGCTTGGGCTG
AAACATCCTTTCGATGATGGCGGGACTGGACGGCCAAATTTTGAAAGCCTGGGGTTGGGAAAGTTCGACCTCGATATGTA
CACCGTCATGTCTTACAGCGACAACGACACGACTGATCTTGCCTACGATCCCGCGACGTTCATGATCCTCGATGTTTTGA
CGCTGCAGCATCTTTATGGCGCGAACGCGTCGCAGAATACGGGGAACGACAGCTACACTCTGGTTCGCGACGATCTCTAT
GACACGATTTACGACGCTGCAGGTCGCGACGCCATTGATCAGTCGAGCGCTCTGGAAGGCTGGTATATCGAGCTTCCTGA
TGTGTATTTGTCCACTGTGGTGGATACGAGGGCTGGCATGGCAATGTCCATGGCGGCGTCAGCGCTGGCCGTGCCAACTG
ACCTGACATGGCTGGCGGGCGACATCGAAGATGCGACCGGTAGCGGGTTTGCCGACATCATCTTCGGATCCGGACTTGCC
AACGATGTGTCTGGTTTGGGCGGCGACGACATCTTGTCGGGCGAAGCGGTCGACTGGAATTATGATGAAATCGCAGGACA
GGTCGTGCGGCTCTACCAGGCGACGCTTGACCGGTTGCCGGACCTGGCCGGTCAGGCATTCTACACGGACGCGCTCGGGA
AGGGTGCACCGCTGGCGGGGCTGGCGGCGAACTTCGCGGCCTCGCCGGAGTTTATCGCCGCCTATGGCGCAACCTCAAAC
GCAGATTTCGTCTCGCTTCTCTACAACAACGTGCTCGACCGAACGCCGTTGCAGTCAGAGGTCAATTTCTACGCGAACCA
ACTCGCAGGTGGCGTCCCTCGTGAGAACATTGTTGTGAACTTCTCGGAAAGCCCGGAATTCGTTCATAAGTCGTTGCCCG
ATGCGCTTGGATTTAGTGTCGCGGCCAAGGCGGCGGACGTCTCTGACGATGTCGTGCGGCTCTATCAGGCGTCGCTGGAC
CGGTTGCCGGACGCCGCCGGTTTTGAGTTCTATGTCGACCTCCTTGCAGGTGGTACCGACCACCTCACGGTCGCGCAGGG
CTTGGTGGCCTCGCCCGAGTTCCAGAGCACCTACGGTGCGCTGTCTGACGCCGACTTTATCGGCCTGCTTTACAACAACG
TGCTGGGACGTATGCCAGCGCCGACGGAAGTCGCGTTCTACGAGACCCAGATGGCGGGCGGTGCGTCCCGGACCGCGGTC
CTCGTGGGTTTTGCGCAAAGCCCGGAGTTCCAGGCAAGCTTCGCGCCCACTGTCGAGAGCTGGCTCAAGAGCCAAGGTGT
CAACGACACGCTCGACGGGGGGACCGGCAACGATGTGCTTATGGGTGGTCTGTGGGCAGACGAGTTCCGGTTCTCGGCAA
GTGACGGTGGGGTCGACAAGATCCTGGATTTTGAGATGTGGGATACGATCATTCTTGATGGCTTTGGCTTCGCCACCACG
GCAGCTGCCGCAAATGCCTTTACTCAGCAGGGCAACGATGCCGTGCTCGTCCACGGCAATGGCGAAATCCACCTCCTTGG
CTTCAGTGCCGCAGACCTGACGTCTGACGAATTCCAGTTCGCGTGA

Upstream 100 bases:

>100_bases
CGATTGAAGGTATTGCCTTGTCAGGCGATACTGGCGCAAGCGCCGCATCTGGGGAGTGTCGGTTGTGTGTTAGCGAGTAT
ACCTCGGAGGTTCGTGCGTC

Downstream 100 bases:

>100_bases
GTTACGTGACAGACGCGTGGGCCAGCACCGGCGGTGATCCTGTCAACGGTGCTTCACGGCGCATCGCGGGGCACCGGTAT
GACCTGATCGGGAGTGTCGT

Product: hypothetical protein

Products: NA

Alternate protein names: AP [H]

Number of amino acids: Translated: 681; Mature: 680

Protein sequence:

>681_residues
MSIGNLNGTIVPLTGDDLIDGLASDFKWQLDATRTIDWTLSDGLSGETWYNPGEFIPLFAGLFDGIEPFIDVDFRYVGYH
SHPDVAIAQGSDINLTWDDANALFSSPNTWALAFFPQPGSLPRGEIYFNSRSDLNYQSSYAPGSQGFFVPLHEVGHALGL
KHPFDDGGTGRPNFESLGLGKFDLDMYTVMSYSDNDTTDLAYDPATFMILDVLTLQHLYGANASQNTGNDSYTLVRDDLY
DTIYDAAGRDAIDQSSALEGWYIELPDVYLSTVVDTRAGMAMSMAASALAVPTDLTWLAGDIEDATGSGFADIIFGSGLA
NDVSGLGGDDILSGEAVDWNYDEIAGQVVRLYQATLDRLPDLAGQAFYTDALGKGAPLAGLAANFAASPEFIAAYGATSN
ADFVSLLYNNVLDRTPLQSEVNFYANQLAGGVPRENIVVNFSESPEFVHKSLPDALGFSVAAKAADVSDDVVRLYQASLD
RLPDAAGFEFYVDLLAGGTDHLTVAQGLVASPEFQSTYGALSDADFIGLLYNNVLGRMPAPTEVAFYETQMAGGASRTAV
LVGFAQSPEFQASFAPTVESWLKSQGVNDTLDGGTGNDVLMGGLWADEFRFSASDGGVDKILDFEMWDTIILDGFGFATT
AAAANAFTQQGNDAVLVHGNGEIHLLGFSAADLTSDEFQFA

Sequences:

>Translated_681_residues
MSIGNLNGTIVPLTGDDLIDGLASDFKWQLDATRTIDWTLSDGLSGETWYNPGEFIPLFAGLFDGIEPFIDVDFRYVGYH
SHPDVAIAQGSDINLTWDDANALFSSPNTWALAFFPQPGSLPRGEIYFNSRSDLNYQSSYAPGSQGFFVPLHEVGHALGL
KHPFDDGGTGRPNFESLGLGKFDLDMYTVMSYSDNDTTDLAYDPATFMILDVLTLQHLYGANASQNTGNDSYTLVRDDLY
DTIYDAAGRDAIDQSSALEGWYIELPDVYLSTVVDTRAGMAMSMAASALAVPTDLTWLAGDIEDATGSGFADIIFGSGLA
NDVSGLGGDDILSGEAVDWNYDEIAGQVVRLYQATLDRLPDLAGQAFYTDALGKGAPLAGLAANFAASPEFIAAYGATSN
ADFVSLLYNNVLDRTPLQSEVNFYANQLAGGVPRENIVVNFSESPEFVHKSLPDALGFSVAAKAADVSDDVVRLYQASLD
RLPDAAGFEFYVDLLAGGTDHLTVAQGLVASPEFQSTYGALSDADFIGLLYNNVLGRMPAPTEVAFYETQMAGGASRTAV
LVGFAQSPEFQASFAPTVESWLKSQGVNDTLDGGTGNDVLMGGLWADEFRFSASDGGVDKILDFEMWDTIILDGFGFATT
AAAANAFTQQGNDAVLVHGNGEIHLLGFSAADLTSDEFQFA
>Mature_680_residues
SIGNLNGTIVPLTGDDLIDGLASDFKWQLDATRTIDWTLSDGLSGETWYNPGEFIPLFAGLFDGIEPFIDVDFRYVGYHS
HPDVAIAQGSDINLTWDDANALFSSPNTWALAFFPQPGSLPRGEIYFNSRSDLNYQSSYAPGSQGFFVPLHEVGHALGLK
HPFDDGGTGRPNFESLGLGKFDLDMYTVMSYSDNDTTDLAYDPATFMILDVLTLQHLYGANASQNTGNDSYTLVRDDLYD
TIYDAAGRDAIDQSSALEGWYIELPDVYLSTVVDTRAGMAMSMAASALAVPTDLTWLAGDIEDATGSGFADIIFGSGLAN
DVSGLGGDDILSGEAVDWNYDEIAGQVVRLYQATLDRLPDLAGQAFYTDALGKGAPLAGLAANFAASPEFIAAYGATSNA
DFVSLLYNNVLDRTPLQSEVNFYANQLAGGVPRENIVVNFSESPEFVHKSLPDALGFSVAAKAADVSDDVVRLYQASLDR
LPDAAGFEFYVDLLAGGTDHLTVAQGLVASPEFQSTYGALSDADFIGLLYNNVLGRMPAPTEVAFYETQMAGGASRTAVL
VGFAQSPEFQASFAPTVESWLKSQGVNDTLDGGTGNDVLMGGLWADEFRFSASDGGVDKILDFEMWDTIILDGFGFATTA
AAANAFTQQGNDAVLVHGNGEIHLLGFSAADLTSDEFQFA

Specific function: Unknown

COG id: COG2931

COG function: function code Q; RTX toxins and related Ca2+-binding proteins

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 hemolysin-type calcium-binding repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018511
- InterPro:   IPR001343
- InterPro:   IPR016294
- InterPro:   IPR013858
- InterPro:   IPR006026
- InterPro:   IPR011049 [H]

Pfam domain/function: PF00353 HemolysinCabind; PF08548 Peptidase_M10_C [H]

EC number: NA

Molecular weight: Translated: 72793; Mature: 72661

Theoretical pI: Translated: 3.73; Mature: 3.73

Prosite motif: PS00330 HEMOLYSIN_CALCIUM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIGNLNGTIVPLTGDDLIDGLASDFKWQLDATRTIDWTLSDGLSGETWYNPGEFIPLFA
CCCCCCCCEEEEECCHHHHHHHHHCCEEEEECCEEEEEEECCCCCCCCCCCCCCHHHHHH
GLFDGIEPFIDVDFRYVGYHSHPDVAIAQGSDINLTWDDANALFSSPNTWALAFFPQPGS
HHHHCCCCCEECCEEEEEECCCCCEEEECCCCEEEEECCCHHHCCCCCCEEEEEECCCCC
LPRGEIYFNSRSDLNYQSSYAPGSQGFFVPLHEVGHALGLKHPFDDGGTGRPNFESLGLG
CCCCEEEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHCCCCCCCCCCCCCCCHHHCCCC
KFDLDMYTVMSYSDNDTTDLAYDPATFMILDVLTLQHLYGANASQNTGNDSYTLVRDDLY
EECCEEEEEEEECCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHH
DTIYDAAGRDAIDQSSALEGWYIELPDVYLSTVVDTRAGMAMSMAASALAVPTDLTWLAG
HHHHHHCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEC
DIEDATGSGFADIIFGSGLANDVSGLGGDDILSGEAVDWNYDEIAGQVVRLYQATLDRLP
CCCCCCCCCEEEEEECCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCH
DLAGQAFYTDALGKGAPLAGLAANFAASPEFIAAYGATSNADFVSLLYNNVLDRTPLQSE
HHCCCCEEHHHCCCCCCCHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCHHH
VNFYANQLAGGVPRENIVVNFSESPEFVHKSLPDALGFSVAAKAADVSDDVVRLYQASLD
HHHHHHHHCCCCCCCCEEEEECCCHHHHHHHCCHHHCCHHHHHCCCCHHHHHHHHHHHHH
RLPDAAGFEFYVDLLAGGTDHLTVAQGLVASPEFQSTYGALSDADFIGLLYNNVLGRMPA
HCCCCCCHHHHHHHHHCCCCCCHHHHCCCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCCC
PTEVAFYETQMAGGASRTAVLVGFAQSPEFQASFAPTVESWLKSQGVNDTLDGGTGNDVL
CCEEEEEEEHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEE
MGGLWADEFRFSASDGGVDKILDFEMWDTIILDGFGFATTAAAANAFTQQGNDAVLVHGN
EECEEHHHEEEECCCCCHHHHCCHHHHCEEEECCCCHHHHHHHHHHHHCCCCCEEEEECC
GEIHLLGFSAADLTSDEFQFA
CEEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
SIGNLNGTIVPLTGDDLIDGLASDFKWQLDATRTIDWTLSDGLSGETWYNPGEFIPLFA
CCCCCCCEEEEECCHHHHHHHHHCCEEEEECCEEEEEEECCCCCCCCCCCCCCHHHHHH
GLFDGIEPFIDVDFRYVGYHSHPDVAIAQGSDINLTWDDANALFSSPNTWALAFFPQPGS
HHHHCCCCCEECCEEEEEECCCCCEEEECCCCEEEEECCCHHHCCCCCCEEEEEECCCCC
LPRGEIYFNSRSDLNYQSSYAPGSQGFFVPLHEVGHALGLKHPFDDGGTGRPNFESLGLG
CCCCEEEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHCCCCCCCCCCCCCCCHHHCCCC
KFDLDMYTVMSYSDNDTTDLAYDPATFMILDVLTLQHLYGANASQNTGNDSYTLVRDDLY
EECCEEEEEEEECCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHH
DTIYDAAGRDAIDQSSALEGWYIELPDVYLSTVVDTRAGMAMSMAASALAVPTDLTWLAG
HHHHHHCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEC
DIEDATGSGFADIIFGSGLANDVSGLGGDDILSGEAVDWNYDEIAGQVVRLYQATLDRLP
CCCCCCCCCEEEEEECCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCH
DLAGQAFYTDALGKGAPLAGLAANFAASPEFIAAYGATSNADFVSLLYNNVLDRTPLQSE
HHCCCCEEHHHCCCCCCCHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCHHH
VNFYANQLAGGVPRENIVVNFSESPEFVHKSLPDALGFSVAAKAADVSDDVVRLYQASLD
HHHHHHHHCCCCCCCCEEEEECCCHHHHHHHCCHHHCCHHHHHCCCCHHHHHHHHHHHHH
RLPDAAGFEFYVDLLAGGTDHLTVAQGLVASPEFQSTYGALSDADFIGLLYNNVLGRMPA
HCCCCCCHHHHHHHHHCCCCCCHHHHCCCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCCC
PTEVAFYETQMAGGASRTAVLVGFAQSPEFQASFAPTVESWLKSQGVNDTLDGGTGNDVL
CCEEEEEEEHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEE
MGGLWADEFRFSASDGGVDKILDFEMWDTIILDGFGFATTAAAANAFTQQGNDAVLVHGN
EECEEHHHEEEECCCCCHHHHCCHHHHCEEEECCCCHHHHHHHHHHHHCCCCCEEEEECC
GEIHLLGFSAADLTSDEFQFA
CEEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1427098; 2123832; 10984043; 8253063; 8690704 [H]