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The map label for this gene is fba [H]

Identifier: 89053908

GI number: 89053908

Start: 1385729

End: 1386568

Strand: Reverse

Name: fba [H]

Synonym: Jann_1417

Alternate gene names: 89053908

Gene position: 1386568-1385729 (Counterclockwise)

Preceding gene: 89053909

Following gene: 89053907

Centisome position: 32.11

GC content: 60.6

Gene sequence:

>840_bases
ATGACCCTCGCGACGCTTGCTGACGTTTTGCGCCCTGCCATGGCAGGTGGCTACGCTGTTCCCGGCCTCGTTTGTCTGGG
ATGGGAGGACATGCGGGCGTTTACCATGGCCGCAGAGGCAGAGGGCGCTCCGGTGATCTTACAGGCCGGGCCGTCATGTC
GCGAACATACGCCTCTGCCGATTTTGGGTAAGATGTTCAGACACTTGGCTGATAATGTTTCGGTTCCCGTCATTGCGCAT
CTGGATCATGGCTATACGATGGAGGAGTGTCAGACCGCGCTGGACGCGGGCTTTACGTCGTTGATGTTCGACGGATCGCG
CCTGCCACTGGCTGAAAATATCGCGCAGACCCGTGCGGTCGTGAAGCTCGCCCATGGGGCGGGCGTCTCAGCCGAGGGGG
AGATCGGATTTGTCGGGTACTCCGGAGGCGAAGACAGCGCGGGGACAGATCCCGACGATGCTGCTGTTTTTGCTCGGGAA
ACTGGCGTCGATGCCATGGCGATCAGTGTCGGAAATGTACATTTACAGCAGGATCGAGAGGGCGGCCTTGATGAGCCGCG
TATCCGTGCGATCGAGGCCATGACAGACGTTCCGTTGGTGATCCATGGCGGGTCCGGCGTGCCTGACGCGCAGCGGATGG
CATTGGCCGCTGGGTCCGCAATTGCCAAGTTCAACATCGGGACTGAGCTGCGTATGGCCTTTGGCGCCGCGCTGCGAGAG
GCCGTCAACGCCGACGAAACGCGATTTGACCGTATTCAGATCCTGCGCGACACCCATGAGCCGGTTTTTAACGCCGCGCG
TCGCGTGTTTCGCGGGATGAATGCCTCAGGAAAAGGGTAG

Upstream 100 bases:

>100_bases
GAGGGTTGTCTCAACGCAGCTTGAAGCAGTACTTTCAGCCGACCCATTCTGAACAATTACACACGATTCCCGGCATCATG
GACATGGTGGCGAAGTTCAA

Downstream 100 bases:

>100_bases
GCGATGCTGAGAATTGGGCTTCTGGGGTGTGGGCGGATCGGGCAGGTCCACGGGCGGACGATCAAGGCGCTGGACAACGC
ACGGGTGGTTGCGGTCGCGG

Product: fructose-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MTLATLADVLRPAMAGGYAVPGLVCLGWEDMRAFTMAAEAEGAPVILQAGPSCREHTPLPILGKMFRHLADNVSVPVIAH
LDHGYTMEECQTALDAGFTSLMFDGSRLPLAENIAQTRAVVKLAHGAGVSAEGEIGFVGYSGGEDSAGTDPDDAAVFARE
TGVDAMAISVGNVHLQQDREGGLDEPRIRAIEAMTDVPLVIHGGSGVPDAQRMALAAGSAIAKFNIGTELRMAFGAALRE
AVNADETRFDRIQILRDTHEPVFNAARRVFRGMNASGKG

Sequences:

>Translated_279_residues
MTLATLADVLRPAMAGGYAVPGLVCLGWEDMRAFTMAAEAEGAPVILQAGPSCREHTPLPILGKMFRHLADNVSVPVIAH
LDHGYTMEECQTALDAGFTSLMFDGSRLPLAENIAQTRAVVKLAHGAGVSAEGEIGFVGYSGGEDSAGTDPDDAAVFARE
TGVDAMAISVGNVHLQQDREGGLDEPRIRAIEAMTDVPLVIHGGSGVPDAQRMALAAGSAIAKFNIGTELRMAFGAALRE
AVNADETRFDRIQILRDTHEPVFNAARRVFRGMNASGKG
>Mature_278_residues
TLATLADVLRPAMAGGYAVPGLVCLGWEDMRAFTMAAEAEGAPVILQAGPSCREHTPLPILGKMFRHLADNVSVPVIAHL
DHGYTMEECQTALDAGFTSLMFDGSRLPLAENIAQTRAVVKLAHGAGVSAEGEIGFVGYSGGEDSAGTDPDDAAVFARET
GVDAMAISVGNVHLQQDREGGLDEPRIRAIEAMTDVPLVIHGGSGVPDAQRMALAAGSAIAKFNIGTELRMAFGAALREA
VNADETRFDRIQILRDTHEPVFNAARRVFRGMNASGKG

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1789526, Length=248, Percent_Identity=32.6612903225806, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1788072, Length=235, Percent_Identity=35.7446808510638, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI87082041, Length=247, Percent_Identity=31.9838056680162, Blast_Score=124, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011289
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 29369; Mature: 29238

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLATLADVLRPAMAGGYAVPGLVCLGWEDMRAFTMAAEAEGAPVILQAGPSCREHTPLP
CCHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCC
ILGKMFRHLADNVSVPVIAHLDHGYTMEECQTALDAGFTSLMFDGSRLPLAENIAQTRAV
HHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHCCCHHEEECCCCCCHHHHHHHHHHH
VKLAHGAGVSAEGEIGFVGYSGGEDSAGTDPDDAAVFARETGVDAMAISVGNVHLQQDRE
HHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCHHEEEEHHCCCCEEEEEECCEEEECCCC
GGLDEPRIRAIEAMTDVPLVIHGGSGVPDAQRMALAAGSAIAKFNIGTELRMAFGAALRE
CCCCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHH
AVNADETRFDRIQILRDTHEPVFNAARRVFRGMNASGKG
HHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TLATLADVLRPAMAGGYAVPGLVCLGWEDMRAFTMAAEAEGAPVILQAGPSCREHTPLP
CHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCC
ILGKMFRHLADNVSVPVIAHLDHGYTMEECQTALDAGFTSLMFDGSRLPLAENIAQTRAV
HHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHCCCHHEEECCCCCCHHHHHHHHHHH
VKLAHGAGVSAEGEIGFVGYSGGEDSAGTDPDDAAVFARETGVDAMAISVGNVHLQQDRE
HHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCHHEEEEHHCCCCEEEEEECCEEEECCCC
GGLDEPRIRAIEAMTDVPLVIHGGSGVPDAQRMALAAGSAIAKFNIGTELRMAFGAALRE
CCCCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHH
AVNADETRFDRIQILRDTHEPVFNAARRVFRGMNASGKG
HHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA