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The map label for this gene is atoS [H]

Identifier: 89053137

GI number: 89053137

Start: 616749

End: 618203

Strand: Direct

Name: atoS [H]

Synonym: Jann_0646

Alternate gene names: 89053137

Gene position: 616749-618203 (Clockwise)

Preceding gene: 89053136

Following gene: 89053138

Centisome position: 14.28

GC content: 62.68

Gene sequence:

>1455_bases
TTGTGCAAAGGTTCGGTCGGCCTTAGATTAGGAGACAGCCCGGGCTCCGGGACCAAGAAGGAGCCGTTCGTGGCCAACTC
ACTCTCTGGGCGATTTCTGATCCTCACCATCATCTTCGTGATGCTGGCAGAGGTGTTCATCTTCGTCCCGTCCATTGCGC
GGTTCCGCGAAGAATACTTGCTGGCCCGTCTGGAGCGGGCGCAGATCGCATCGCTGGCGTTGCTGGCCACTGACGGGATG
ATCGACGACGATCTGGAATATGAGCTGCTGGAGAATGCAGAGGTCCTGAACGTCGTGCTGGCGCGCAATTCGATGCGGCA
GCTTATCCTGTCGACGGAAGGGATGGAGCCGATCTCGGGCTCGTATGATTTGCGTTACGCGACCGCGTGGGATCTGATTC
GGGATGCGTCCATGCGGATTTTCGAGACGGAGAACCAGAACATCCGCGTCATCGGACGGCCCGTGCGCAACGCGGGCGAT
TCGATTGAGGTCACGATGGAAACCGCGCCCTTGCGCATGGCGATGCTTGATTATGGGTTGCGCGTTCTGATCCTGTCGGC
GGTGATCTCCATCTTCACGGCCATATTGTTGTTCGTGGCCGTCCGGGTGCTGATGGTGAACCCGATCAAACGGGTTGTGG
GCGCCATGATGACCTATGCGGAAGCGCCGGCCGATGCGAACCGGATCATCACGCCGCGCGGCACGGTGCGTGAGTTGCGC
AATGCCGAAGACGCCCTGCATGCCATGCAGACGCAGCTGACGTCACTATTGCGGCAGCGCGAACGCTTGGCGCAATTGGG
CGAGGCGGTGGCGAAGATCAGCCACGATCTGCGCAACATGCTGTCGGTCGCCACCCTTGTCGCGGATCGGCTGGAGACGG
TTCAGGACCCGACCGTGAAGCGCATTGCGCCCAAGCTGATCAACTCCCTCAGCCGCGCGATCAATCTGACGGAGGCAACG
CTGGCCTTTGGCCGGGCGGAGGAGCCCGCCCCGAAGCTGGACCGCGTCCCGCTGGAGCCATTGGTGGATGACGTGCTGGA
CAACGATAACCTCGCCCAGGGCGACGGCGAGGTCAGCTATGATGCGGAGATCGCGCATGGCATGGTCGTGCGCGCCGACC
CCGAGCAATTGCACCGCGTCCTGTCCAATCTGGTGCGCAACGCGCGGCAGGCTATCGCGGCAACAGGCGCGCCCGGCGAA
GTCACTATTCGCGGGGGCGAGCATGAGGGCGGCTGGCGGATTGAGGTGTGCGATACCGGTCCCGGCCTGCCCGGCAAGGC
GCAGGAGAGCCTTTTCAAACCGTTCTCATCCACCGACAAAGTTGGTGGCACGGGCCTTGGCCTTGCCATCTGCGCCGAGA
TCCTGCGCGGCCATGGGGGGCAGTTGAAACTGCTCAGTACCGGGCCCGAGGGCACAACCTTCGCCTTATACCTTCCCGGT
GGCATGGCGGCCTGA

Upstream 100 bases:

>100_bases
GCCCCCTATCCGACATTGGGAGAGATCAACAAACGCGCTGCCAGTGCCTATTTCACCCCCAAGCTGTTCGACAGTGCGCT
GGTGAAAAAGGTCGTGCGGT

Downstream 100 bases:

>100_bases
TTGCCCCTTGCACTGATGAGACGGCGGGGTTACATGCACCCCACGCGGATTGGTAGCTCAGCTGGATAGAGTACTTGACT
ACGAATCAAGGGGTCGGGGG

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MCKGSVGLRLGDSPGSGTKKEPFVANSLSGRFLILTIIFVMLAEVFIFVPSIARFREEYLLARLERAQIASLALLATDGM
IDDDLEYELLENAEVLNVVLARNSMRQLILSTEGMEPISGSYDLRYATAWDLIRDASMRIFETENQNIRVIGRPVRNAGD
SIEVTMETAPLRMAMLDYGLRVLILSAVISIFTAILLFVAVRVLMVNPIKRVVGAMMTYAEAPADANRIITPRGTVRELR
NAEDALHAMQTQLTSLLRQRERLAQLGEAVAKISHDLRNMLSVATLVADRLETVQDPTVKRIAPKLINSLSRAINLTEAT
LAFGRAEEPAPKLDRVPLEPLVDDVLDNDNLAQGDGEVSYDAEIAHGMVVRADPEQLHRVLSNLVRNARQAIAATGAPGE
VTIRGGEHEGGWRIEVCDTGPGLPGKAQESLFKPFSSTDKVGGTGLGLAICAEILRGHGGQLKLLSTGPEGTTFALYLPG
GMAA

Sequences:

>Translated_484_residues
MCKGSVGLRLGDSPGSGTKKEPFVANSLSGRFLILTIIFVMLAEVFIFVPSIARFREEYLLARLERAQIASLALLATDGM
IDDDLEYELLENAEVLNVVLARNSMRQLILSTEGMEPISGSYDLRYATAWDLIRDASMRIFETENQNIRVIGRPVRNAGD
SIEVTMETAPLRMAMLDYGLRVLILSAVISIFTAILLFVAVRVLMVNPIKRVVGAMMTYAEAPADANRIITPRGTVRELR
NAEDALHAMQTQLTSLLRQRERLAQLGEAVAKISHDLRNMLSVATLVADRLETVQDPTVKRIAPKLINSLSRAINLTEAT
LAFGRAEEPAPKLDRVPLEPLVDDVLDNDNLAQGDGEVSYDAEIAHGMVVRADPEQLHRVLSNLVRNARQAIAATGAPGE
VTIRGGEHEGGWRIEVCDTGPGLPGKAQESLFKPFSSTDKVGGTGLGLAICAEILRGHGGQLKLLSTGPEGTTFALYLPG
GMAA
>Mature_484_residues
MCKGSVGLRLGDSPGSGTKKEPFVANSLSGRFLILTIIFVMLAEVFIFVPSIARFREEYLLARLERAQIASLALLATDGM
IDDDLEYELLENAEVLNVVLARNSMRQLILSTEGMEPISGSYDLRYATAWDLIRDASMRIFETENQNIRVIGRPVRNAGD
SIEVTMETAPLRMAMLDYGLRVLILSAVISIFTAILLFVAVRVLMVNPIKRVVGAMMTYAEAPADANRIITPRGTVRELR
NAEDALHAMQTQLTSLLRQRERLAQLGEAVAKISHDLRNMLSVATLVADRLETVQDPTVKRIAPKLINSLSRAINLTEAT
LAFGRAEEPAPKLDRVPLEPLVDDVLDNDNLAQGDGEVSYDAEIAHGMVVRADPEQLHRVLSNLVRNARQAIAATGAPGE
VTIRGGEHEGGWRIEVCDTGPGLPGKAQESLFKPFSSTDKVGGTGLGLAICAEILRGHGGQLKLLSTGPEGTTFALYLPG
GMAA

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=227, Percent_Identity=32.15859030837, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1790436, Length=234, Percent_Identity=31.1965811965812, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1790300, Length=127, Percent_Identity=38.5826771653543, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788393, Length=295, Percent_Identity=24.7457627118644, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87082128, Length=314, Percent_Identity=25.1592356687898, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788713, Length=119, Percent_Identity=33.6134453781513, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786600, Length=225, Percent_Identity=27.1111111111111, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786912, Length=114, Percent_Identity=34.2105263157895, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52531; Mature: 52531

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCKGSVGLRLGDSPGSGTKKEPFVANSLSGRFLILTIIFVMLAEVFIFVPSIARFREEYL
CCCCCCCEEECCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LARLERAQIASLALLATDGMIDDDLEYELLENAEVLNVVLARNSMRQLILSTEGMEPISG
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SYDLRYATAWDLIRDASMRIFETENQNIRVIGRPVRNAGDSIEVTMETAPLRMAMLDYGL
CCCEEHHHHHHHHHHCCCEEEECCCCCEEEEECCCCCCCCCEEEEEECCCHHHHHHHHHH
RVLILSAVISIFTAILLFVAVRVLMVNPIKRVVGAMMTYAEAPADANRIITPRGTVRELR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCHHHHHHH
NAEDALHAMQTQLTSLLRQRERLAQLGEAVAKISHDLRNMLSVATLVADRLETVQDPTVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
RIAPKLINSLSRAINLTEATLAFGRAEEPAPKLDRVPLEPLVDDVLDNDNLAQGDGEVSY
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEE
DAEIAHGMVVRADPEQLHRVLSNLVRNARQAIAATGAPGEVTIRGGEHEGGWRIEVCDTG
CCHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEECCC
PGLPGKAQESLFKPFSSTDKVGGTGLGLAICAEILRGHGGQLKLLSTGPEGTTFALYLPG
CCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEECCC
GMAA
CCCC
>Mature Secondary Structure
MCKGSVGLRLGDSPGSGTKKEPFVANSLSGRFLILTIIFVMLAEVFIFVPSIARFREEYL
CCCCCCCEEECCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LARLERAQIASLALLATDGMIDDDLEYELLENAEVLNVVLARNSMRQLILSTEGMEPISG
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SYDLRYATAWDLIRDASMRIFETENQNIRVIGRPVRNAGDSIEVTMETAPLRMAMLDYGL
CCCEEHHHHHHHHHHCCCEEEECCCCCEEEEECCCCCCCCCEEEEEECCCHHHHHHHHHH
RVLILSAVISIFTAILLFVAVRVLMVNPIKRVVGAMMTYAEAPADANRIITPRGTVRELR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCHHHHHHH
NAEDALHAMQTQLTSLLRQRERLAQLGEAVAKISHDLRNMLSVATLVADRLETVQDPTVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
RIAPKLINSLSRAINLTEATLAFGRAEEPAPKLDRVPLEPLVDDVLDNDNLAQGDGEVSY
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEE
DAEIAHGMVVRADPEQLHRVLSNLVRNARQAIAATGAPGEVTIRGGEHEGGWRIEVCDTG
CCHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEECCC
PGLPGKAQESLFKPFSSTDKVGGTGLGLAICAEILRGHGGQLKLLSTGPEGTTFALYLPG
CCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEECCC
GMAA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]