Click here to switch to the map view.

The map label for this gene is gph [C]

Identifier: 89053116

GI number: 89053116

Start: 597830

End: 598495

Strand: Direct

Name: gph [C]

Synonym: Jann_0625

Alternate gene names: 89053116

Gene position: 597830-598495 (Clockwise)

Preceding gene: 89053115

Following gene: 89053117

Centisome position: 13.85

GC content: 66.97

Gene sequence:

>666_bases
TTGACACTGAAACTGGTGATCTTCGACGTGGACGGCACGCTGGTCGATTCCATCGCCCAGATTGAAACGGTGGTGAACCG
GGCCTTCGCCGCCCGCGGTTACGCGCCGCCCCCGCCCGGCGCGGTGCGCGGCCTTGTCGGGATATCGTTGCCGGAGCTGA
TGGCCGCGCTGAAGCCGGATCTGGACGCCCCTGCCATTGGCGCCCTGGTGGAGGCCTACAAACGCACTTTCGTGCAATCG
GCCACGCGCGAGGCCTCGCCGCTGTTTCCCGGAACGCTGGAGATGCTGAGCAGGCTGGCGGGCCGCGACGATCTGCTTCT
GGGCATCGCAACGGGCAAATCCCGGCGCGGGCTGGACAGGATCCTGCGGGAAAACGGGTTGGAGAGGCATTTCGTGACCC
GGCAGGTGGCCGATGATCACCCGTCCAAACCGCATCCGTCGATGGTGCTGAGCGCGCTGGCGGAGACCGGCATCGAGGCG
GAGGGGGCCGTGCTGATCGGCGACACGACCTTTGATCTTCAGATGGCCCAGGCGGCCGGGGTCAGGGGGATCGGCGTGGC
GTGGGGAAACCATGCGGCGGAGGATCTGCAGCCCCTGGCCAATCACATGCTGGGGGACTGGACGGCGTTGGACCCGTGTC
TTGACACCCTGTGGGAGGCCCGATGA

Upstream 100 bases:

>100_bases
ATCTGGTCGCGCCGCTGCCCGAGCATATGGCGAAGACGTGGGACACCCTCGGCTGGGACCCGCGCGATGTGCCCGCAGAC
CCGTTCGAGGATGATGCGTT

Downstream 100 bases:

>100_bases
CCGAGTGGAAAGCGAAACGGTTCTGGACCGAGGCGACGGTGGCCGAGGCGGATGGCGGGTTCAAAGTGCTTCTGGACGGG
CGCGGTGTGAACACGCCGGG

Product: HAD family hydrolase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MTLKLVIFDVDGTLVDSIAQIETVVNRAFAARGYAPPPPGAVRGLVGISLPELMAALKPDLDAPAIGALVEAYKRTFVQS
ATREASPLFPGTLEMLSRLAGRDDLLLGIATGKSRRGLDRILRENGLERHFVTRQVADDHPSKPHPSMVLSALAETGIEA
EGAVLIGDTTFDLQMAQAAGVRGIGVAWGNHAAEDLQPLANHMLGDWTALDPCLDTLWEAR

Sequences:

>Translated_221_residues
MTLKLVIFDVDGTLVDSIAQIETVVNRAFAARGYAPPPPGAVRGLVGISLPELMAALKPDLDAPAIGALVEAYKRTFVQS
ATREASPLFPGTLEMLSRLAGRDDLLLGIATGKSRRGLDRILRENGLERHFVTRQVADDHPSKPHPSMVLSALAETGIEA
EGAVLIGDTTFDLQMAQAAGVRGIGVAWGNHAAEDLQPLANHMLGDWTALDPCLDTLWEAR
>Mature_220_residues
TLKLVIFDVDGTLVDSIAQIETVVNRAFAARGYAPPPPGAVRGLVGISLPELMAALKPDLDAPAIGALVEAYKRTFVQSA
TREASPLFPGTLEMLSRLAGRDDLLLGIATGKSRRGLDRILRENGLERHFVTRQVADDHPSKPHPSMVLSALAETGIEAE
GAVLIGDTTFDLQMAQAAGVRGIGVAWGNHAAEDLQPLANHMLGDWTALDPCLDTLWEAR

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 23593; Mature: 23462

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLKLVIFDVDGTLVDSIAQIETVVNRAFAARGYAPPPPGAVRGLVGISLPELMAALKPD
CEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHCCC
LDAPAIGALVEAYKRTFVQSATREASPLFPGTLEMLSRLAGRDDLLLGIATGKSRRGLDR
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHH
ILRENGLERHFVTRQVADDHPSKPHPSMVLSALAETGIEAEGAVLIGDTTFDLQMAQAAG
HHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHCC
VRGIGVAWGNHAAEDLQPLANHMLGDWTALDPCLDTLWEAR
CCEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLKLVIFDVDGTLVDSIAQIETVVNRAFAARGYAPPPPGAVRGLVGISLPELMAALKPD
EEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHCCC
LDAPAIGALVEAYKRTFVQSATREASPLFPGTLEMLSRLAGRDDLLLGIATGKSRRGLDR
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHH
ILRENGLERHFVTRQVADDHPSKPHPSMVLSALAETGIEAEGAVLIGDTTFDLQMAQAAG
HHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHCC
VRGIGVAWGNHAAEDLQPLANHMLGDWTALDPCLDTLWEAR
CCEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA