BacMap

Definition	Jannaschia sp. CCS1 chromosome, complete genome.
Accession	NC_007802
Length	4,317,977

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The map label for this gene is phaB [H]

Identifier: 89052983

GI number: 89052983

Start: 490688

End: 491410

Strand: Reverse

Name: phaB [H]

Synonym: Jann_0492

Alternate gene names: 89052983

Gene position: 491410-490688 (Counterclockwise)

Preceding gene: 89052984

Following gene: 89052982

Centisome position: 11.38

GC content: 61.69

Gene sequence:

>723_bases
ATGGGACGAGTCGCACTGGTCACCGGCGGAAGCCGCGGCATTGGCGAAGCCATTTCCAAGGCCCTGCAAGCCGACGGCTA
TACCGTCGCCGCCACCTATGCGGGCAACGACGAGGCCGCCGCCAAGTTCACCGACGCCACGGGCATCAAGACCTACAAGT
GGAACGTTGCCGACTATGACAGCTCCAAAGCAGGCATCGAACAGGTCGAATCGGATCTTGGCCCCATCGAGGTTGTCGTC
GCCAACGCAGGCATCACCCGCGACGCCCCGTTCCACAAAATGACGCCCCAGCAGTGGAATGAGGTGATCGACACCAACCT
GACCGGCGTGTTCAACACCGTGCACCCGATCTGGCCCGGCATGCGCGAGCGGAAGTTTGGCCGCGTTATCGTGATCTCTT
CAATCAACGGCCAGAAGGGTCAGTTCGCACAAACAAACTATGCCGCCACGAAAGCGGGCGATCTCGGCATCGTGAAGTCT
CTGGCCCAGGAAGGCGCGCGCGCCGGCATCACCGCCAACGCGATCTGCCCCGGCTATATTGCGACGGAAATGGTCATGGC
GATCCCGGAGAAGGTACGTGACAGCATCGTCGCGGGCATTCCTGCCGGTCGTCTGGGCGAGCCAGAGGAAATCGCACGCT
GCGTCTGCTTCCTGGCGTCGGACGATAGCGGGTTCATCAACGGCTCGACCATCTCGGCCAACGGTGCGCAATTCTTCGTC
TAA

Upstream 100 bases:

>100_bases
AGCGGGACTGATCACCCTTACATCGCAGGCCGTGCGCAATAAATTTGCGCGCGGCCCTTTCTTTGCGTAACAAAGTTATA
AACTTCAGAAGGAGAGACAC

Downstream 100 bases:

>100_bases
AGAGTACCCCCAGATGCATGAAAGCCCCCGAGCAATCCTCGGGGGCTTTTTCGTGTCTGTCGCGCGGCTCTGATCGCAGT
GGCCGGACATACCTTGGGCC

Product: acetoacetyl-CoA reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MGRVALVTGGSRGIGEAISKALQADGYTVAATYAGNDEAAAKFTDATGIKTYKWNVADYDSSKAGIEQVESDLGPIEVVV
ANAGITRDAPFHKMTPQQWNEVIDTNLTGVFNTVHPIWPGMRERKFGRVIVISSINGQKGQFAQTNYAATKAGDLGIVKS
LAQEGARAGITANAICPGYIATEMVMAIPEKVRDSIVAGIPAGRLGEPEEIARCVCFLASDDSGFINGSTISANGAQFFV

Sequences:

>Translated_240_residues
MGRVALVTGGSRGIGEAISKALQADGYTVAATYAGNDEAAAKFTDATGIKTYKWNVADYDSSKAGIEQVESDLGPIEVVV
ANAGITRDAPFHKMTPQQWNEVIDTNLTGVFNTVHPIWPGMRERKFGRVIVISSINGQKGQFAQTNYAATKAGDLGIVKS
LAQEGARAGITANAICPGYIATEMVMAIPEKVRDSIVAGIPAGRLGEPEEIARCVCFLASDDSGFINGSTISANGAQFFV
>Mature_239_residues
GRVALVTGGSRGIGEAISKALQADGYTVAATYAGNDEAAAKFTDATGIKTYKWNVADYDSSKAGIEQVESDLGPIEVVVA
NAGITRDAPFHKMTPQQWNEVIDTNLTGVFNTVHPIWPGMRERKFGRVIVISSINGQKGQFAQTNYAATKAGDLGIVKSL
AQEGARAGITANAICPGYIATEMVMAIPEKVRDSIVAGIPAGRLGEPEEIARCVCFLASDDSGFINGSTISANGAQFFV

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=251, Percent_Identity=39.0438247011952, Blast_Score=156, Evalue=1e-38,
Organism=Homo sapiens, GI40254992, Length=236, Percent_Identity=31.7796610169492, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI4504505, Length=233, Percent_Identity=35.1931330472103, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI19923817, Length=250, Percent_Identity=29.6, Blast_Score=94, Evalue=9e-20,
Organism=Homo sapiens, GI7705925, Length=238, Percent_Identity=27.7310924369748, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI32483357, Length=246, Percent_Identity=29.2682926829268, Blast_Score=90, Evalue=1e-18,
Organism=Homo sapiens, GI66933014, Length=241, Percent_Identity=27.8008298755187, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI4758504, Length=253, Percent_Identity=28.8537549407115, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI5031737, Length=240, Percent_Identity=28.3333333333333, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI10190704, Length=241, Percent_Identity=26.9709543568465, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI7657478, Length=190, Percent_Identity=29.4736842105263, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI109715829, Length=230, Percent_Identity=25.6521739130435, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI31542939, Length=250, Percent_Identity=28, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI4503301, Length=204, Percent_Identity=27.9411764705882, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI59889578, Length=196, Percent_Identity=29.0816326530612, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI83715985, Length=253, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI223718074, Length=204, Percent_Identity=30.3921568627451, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI126723750, Length=246, Percent_Identity=24.7967479674797, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI4503817, Length=172, Percent_Identity=26.1627906976744, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1787335, Length=241, Percent_Identity=42.7385892116183, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1790717, Length=243, Percent_Identity=34.5679012345679, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI87082100, Length=242, Percent_Identity=34.297520661157, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=31.8367346938775, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789208, Length=243, Percent_Identity=28.8065843621399, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI2367365, Length=238, Percent_Identity=31.0924369747899, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1788459, Length=241, Percent_Identity=27.3858921161826, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI87082160, Length=240, Percent_Identity=27.0833333333333, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1786812, Length=245, Percent_Identity=25.7142857142857, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1789057, Length=256, Percent_Identity=25.78125, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789378, Length=254, Percent_Identity=26.7716535433071, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787905, Length=241, Percent_Identity=25.3112033195021, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787820, Length=155, Percent_Identity=32.9032258064516, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=42.9718875502008, Blast_Score=167, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI17555706, Length=239, Percent_Identity=40.5857740585774, Blast_Score=152, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17568967, Length=232, Percent_Identity=33.1896551724138, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17560676, Length=243, Percent_Identity=31.6872427983539, Blast_Score=103, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17538182, Length=248, Percent_Identity=29.8387096774194, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17561402, Length=241, Percent_Identity=28.2157676348548, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17561272, Length=193, Percent_Identity=30.0518134715026, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=251, Percent_Identity=26.6932270916335, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17536651, Length=252, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17536025, Length=252, Percent_Identity=28.1746031746032, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=266, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=26.5873015873016, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=222, Percent_Identity=25.6756756756757, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193203117, Length=222, Percent_Identity=25.6756756756757, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=186, Percent_Identity=26.3440860215054, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=261, Percent_Identity=27.5862068965517, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=236, Percent_Identity=26.6949152542373, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17567345, Length=192, Percent_Identity=23.9583333333333, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=263, Percent_Identity=26.9961977186312, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17564282, Length=197, Percent_Identity=23.8578680203046, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560150, Length=259, Percent_Identity=26.2548262548263, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=254, Percent_Identity=25.5905511811024, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=28.0769230769231, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17562904, Length=260, Percent_Identity=27.3076923076923, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=253, Percent_Identity=32.8063241106719, Blast_Score=108, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6324126, Length=252, Percent_Identity=26.5873015873016, Blast_Score=77, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320089, Length=194, Percent_Identity=28.3505154639175, Blast_Score=71, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24639444, Length=248, Percent_Identity=35.4838709677419, Blast_Score=140, Evalue=7e-34,
Organism=Drosophila melanogaster, GI21355319, Length=242, Percent_Identity=30.5785123966942, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI18859837, Length=243, Percent_Identity=32.5102880658436, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24643142, Length=239, Percent_Identity=30.1255230125523, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI23397609, Length=243, Percent_Identity=29.2181069958848, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17737361, Length=254, Percent_Identity=29.1338582677165, Blast_Score=80, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24649181, Length=189, Percent_Identity=29.6296296296296, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24641232, Length=232, Percent_Identity=30.6034482758621, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21357041, Length=251, Percent_Identity=27.4900398406374, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI221331218, Length=200, Percent_Identity=32, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24665243, Length=200, Percent_Identity=32, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281364892, Length=168, Percent_Identity=29.1666666666667, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI221331216, Length=201, Percent_Identity=31.3432835820896, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=25.6, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24665247, Length=201, Percent_Identity=31.3432835820896, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI116007236, Length=197, Percent_Identity=27.9187817258883, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24581726, Length=168, Percent_Identity=26.1904761904762, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI116007234, Length=217, Percent_Identity=29.4930875576037, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011283
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.36 [H]

Molecular weight: Translated: 25235; Mature: 25104

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRVALVTGGSRGIGEAISKALQADGYTVAATYAGNDEAAAKFTDATGIKTYKWNVADYD
CCEEEEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCCHHEEECCCCCCEEEEEECCCCC
SSKAGIEQVESDLGPIEVVVANAGITRDAPFHKMTPQQWNEVIDTNLTGVFNTVHPIWPG
CCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCC
MRERKFGRVIVISSINGQKGQFAQTNYAATKAGDLGIVKSLAQEGARAGITANAICPGYI
HHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHCCCEECCCCCHHH
ATEMVMAIPEKVRDSIVAGIPAGRLGEPEEIARCVCFLASDDSGFINGSTISANGAQFFV
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHEEEECCCCCEECCCEEECCCCEECC
>Mature Secondary Structure 
GRVALVTGGSRGIGEAISKALQADGYTVAATYAGNDEAAAKFTDATGIKTYKWNVADYD
CEEEEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCCHHEEECCCCCCEEEEEECCCCC
SSKAGIEQVESDLGPIEVVVANAGITRDAPFHKMTPQQWNEVIDTNLTGVFNTVHPIWPG
CCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCC
MRERKFGRVIVISSINGQKGQFAQTNYAATKAGDLGIVKSLAQEGARAGITANAICPGYI
HHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHCCCEECCCCCHHH
ATEMVMAIPEKVRDSIVAGIPAGRLGEPEEIARCVCFLASDDSGFINGSTISANGAQFFV
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHEEEECCCCCEECCCEEECCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8566717 [H]