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The map label for this gene is yycF [H]

Identifier: 89052908

GI number: 89052908

Start: 420512

End: 421198

Strand: Direct

Name: yycF [H]

Synonym: Jann_0417

Alternate gene names: 89052908

Gene position: 420512-421198 (Clockwise)

Preceding gene: 89052905

Following gene: 89052909

Centisome position: 9.74

GC content: 58.08

Gene sequence:

>687_bases
ATGGCAAACCTCAAGAAAATCCTTCTGGTCGATGACGAAGATGACCTGCGCGAAGCGCTCAGTGAACAGCTTGTGATGAC
CGAGGACTTCGATGTGTTCGAGGCGGCCAATGGCGCCCAGGCGATGGAGCGTGCAAAGGAAGGGATCTACGATCTCGTTA
TCCTCGACGTGGGCCTGCCCGATACCGATGGCCGTGAGCTGTGCCGCCTGATGCGCAAGCAGGGCGTGAAATGCCCGGTT
CTGATGCTGACGGGTCATGACAGTGACGCCGACACGATCCTTGGTCTGGATGCCGGGGCCAACGATTATGTCACCAAACC
CTTCCGTTTTCCGGTGCTTCTGGCCCGTATCCGCGCGCAACTACGCCAGCATGAGCAGTCTGAGGATGCCGTCTTCCAAC
TGGGGCCGTACACGTTCAAGCCCGCCATGAAGATGCTGATCACCGAGGACGAGCGGAAGATCCGCCTGACCGAGAAAGAG
ACCAACATCCTCAAGTTCCTCTACCGTGCCCAGGATGGCGTCGTCGCCCGTGACGTGCTGCTGCATGAGGTTTGGGGCTA
CAATGCCGGTGTCACGACCCACACGTTGGAGACGCATATTTACCGTCTTCGCCAGAAAATTGAGCCAGATCCGTCCAATG
CCCGCCTTCTTGTGACCGAATCTGGTGGGTATCGTCTGGTGGCGTAA

Upstream 100 bases:

>100_bases
GCCGACACAGGGCCGTGAGGCATGGTTACATCCATAGACAAACCGGGTGCGGGCGGGCCATGTCAGGACAACGGAACAAG
ACACGACAGGAACCCGCACC

Downstream 100 bases:

>100_bases
GGAATTCCCCCGGTGCCTGGGACCCGAGTTTGTGGGATAAGGCATCACCTCCCTGTTGTACTGGCCCGGACCTCGTGTCC
GGGCTTTTTTTTGGATGGGC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MANLKKILLVDDEDDLREALSEQLVMTEDFDVFEAANGAQAMERAKEGIYDLVILDVGLPDTDGRELCRLMRKQGVKCPV
LMLTGHDSDADTILGLDAGANDYVTKPFRFPVLLARIRAQLRQHEQSEDAVFQLGPYTFKPAMKMLITEDERKIRLTEKE
TNILKFLYRAQDGVVARDVLLHEVWGYNAGVTTHTLETHIYRLRQKIEPDPSNARLLVTESGGYRLVA

Sequences:

>Translated_228_residues
MANLKKILLVDDEDDLREALSEQLVMTEDFDVFEAANGAQAMERAKEGIYDLVILDVGLPDTDGRELCRLMRKQGVKCPV
LMLTGHDSDADTILGLDAGANDYVTKPFRFPVLLARIRAQLRQHEQSEDAVFQLGPYTFKPAMKMLITEDERKIRLTEKE
TNILKFLYRAQDGVVARDVLLHEVWGYNAGVTTHTLETHIYRLRQKIEPDPSNARLLVTESGGYRLVA
>Mature_227_residues
ANLKKILLVDDEDDLREALSEQLVMTEDFDVFEAANGAQAMERAKEGIYDLVILDVGLPDTDGRELCRLMRKQGVKCPVL
MLTGHDSDADTILGLDAGANDYVTKPFRFPVLLARIRAQLRQHEQSEDAVFQLGPYTFKPAMKMLITEDERKIRLTEKET
NILKFLYRAQDGVVARDVLLHEVWGYNAGVTTHTLETHIYRLRQKIEPDPSNARLLVTESGGYRLVA

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=36.5638766519824, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=36.4444444444444, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=34.7826086956522, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1790552, Length=223, Percent_Identity=35.4260089686099, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=33.7837837837838, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=30.0884955752212, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1787375, Length=219, Percent_Identity=32.8767123287671, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1790860, Length=212, Percent_Identity=34.9056603773585, Blast_Score=102, Evalue=1e-23,
Organism=Escherichia coli, GI1789402, Length=209, Percent_Identity=31.1004784688995, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=29.8701298701299, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1788394, Length=236, Percent_Identity=30.5084745762712, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI2367329, Length=215, Percent_Identity=35.3488372093023, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=29.8701298701299, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1788550, Length=168, Percent_Identity=30.952380952381, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790437, Length=148, Percent_Identity=31.0810810810811, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI145693140, Length=216, Percent_Identity=30.5555555555556, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788191, Length=110, Percent_Identity=35.4545454545455, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788713, Length=117, Percent_Identity=35.8974358974359, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25833; Mature: 25702

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANLKKILLVDDEDDLREALSEQLVMTEDFDVFEAANGAQAMERAKEGIYDLVILDVGLP
CCCCEEEEEECCCHHHHHHHHHHEEECCCCHHHHCCCCHHHHHHHHCCCEEEEEEECCCC
DTDGRELCRLMRKQGVKCPVLMLTGHDSDADTILGLDAGANDYVTKPFRFPVLLARIRAQ
CCCHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHH
LRQHEQSEDAVFQLGPYTFKPAMKMLITEDERKIRLTEKETNILKFLYRAQDGVVARDVL
HHHCCCCCCCEEEECCEEHHHHHHHHEECCCCEEEEEHHHHHHHHHHHHHCCCCHHHHHH
LHEVWGYNAGVTTHTLETHIYRLRQKIEPDPSNARLLVTESGGYRLVA
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEC
>Mature Secondary Structure 
ANLKKILLVDDEDDLREALSEQLVMTEDFDVFEAANGAQAMERAKEGIYDLVILDVGLP
CCCEEEEEECCCHHHHHHHHHHEEECCCCHHHHCCCCHHHHHHHHCCCEEEEEEECCCC
DTDGRELCRLMRKQGVKCPVLMLTGHDSDADTILGLDAGANDYVTKPFRFPVLLARIRAQ
CCCHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHH
LRQHEQSEDAVFQLGPYTFKPAMKMLITEDERKIRLTEKETNILKFLYRAQDGVVARDVL
HHHCCCCCCCEEEECCEEHHHHHHHHEECCCCEEEEEHHHHHHHHHHHHHCCCCHHHHHH
LHEVWGYNAGVTTHTLETHIYRLRQKIEPDPSNARLLVTESGGYRLVA
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]