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The map label for this gene is rnr [H]

Identifier: 89052847

GI number: 89052847

Start: 359493

End: 361829

Strand: Direct

Name: rnr [H]

Synonym: Jann_0356

Alternate gene names: 89052847

Gene position: 359493-361829 (Clockwise)

Preceding gene: 89052845

Following gene: 89052848

Centisome position: 8.33

GC content: 65.77

Gene sequence:

>2337_bases
ATGACGCCCCCGCACCTGCGTGCTACCTCACCCCCCATGAGCAACATCCCTTCCAAAGAGCAGATCCTGCAATGGATCAC
CGACAACCCCGGCAAACGGTCCAAGCGCGATATCGCCAAGGCGTTTGGCATCAAGGGGGCGGCGCGGATTGATCTGAAGC
GGATCCTCAGGGAGTTGCAGGAGGAGGGGCATCTGGAAAAGGTCGGGCGGACCTATCGCGACCCGGACAAACTGCCGCCG
GTGACGATCCTGTCCGTGCAGGCGCCCGACGACAACGGCGATCTGTTTGCGCGGCCTCTGGAATGGCACGGCGAGGGGGT
GGAGCCGCGCGTGCTGTACACGCCTCGGACGGCGGACCCGGCGGTGGGACAGGGCGACCGCATTCTGGCGAAGCTCTTTG
CGGTGGAGGGCTCCGACGCAGAAGACCACCAATATACCGCCAAGCTGATCCGTAAGATCGGGACCAACCCGCGCAAGATC
CTGGGGATTTTCCGCAAGGGGGCGGAGGGGGGCGTGATCACGCCGATCTCCAAAGGGTCCGACAAGGAATGGCAGGTGCG
GGCCGGTGATACGCACGGGGCCAAGGATGGCGAATTGGTGGAGGGGGAGCTGGCCGGGCCCAAGGCGCGGATGGGGGCGC
CGCGGGCCCGGATCACGACGCGCGTGGGCGATCCCGGGGCCGCGCGGGCCGTGTCGCTGATCGCGATCCATGAACATGGC
ATCCCCGACAGCTTCCCCAACAAGGTCGTGGCCGAGGCTGATGCGGCCAAACCCGCCGGCCTGACGGGGCGGGAGGATCT
GCGCGATCTGCCCCTGATCACCATCGACCCGGCGGATGCGCGCGACCATGATGATGCCTGCTATGCCCATGCCGATGAGG
ACCCGGGCAACAAGGGCGGCCATGTCATCTGGGTCGCGATTGCGGATGTGGCCCATTACGTCACGCCCGACAGCGCGCTG
GATCGCGAAGCGCGCAAGCGTGGCAACTCCACCTATTTCCCGGACCGTGTGGTGCCGATGCTGCCGGATCGGTTGTCGGG
CGATCTTTGCTCGTTGCACGAGGGGGTGCCGAGGGCGGTGATCGCGGTGCGGATGGTGATTGACGCCAGGGGCGAGAAAA
TCGGCCACACGTTCCATCGCGGGCTGATGACATCTGTCGCTTCGCTGAGTTACGAGGAGGCGCAGGCGGCGCAGGAGGGC
ACGCTCTCCGAGCGCACCGCGCCCCTCATCGAGGGCTCAATTCGCCCTCTCTTCGCAGCTTATGACGCGTTGAAGATCGC
ACGGGCCAAGCGGCAACCGCTGGAGCTGGACCTGCCGGAGCGGCGGATTGAACTGGATGACGCGGGCAATGTCACCTCGG
TGGCGTTCAAGGATCGCCTGGACGCGCACCGCCTGATTGAGGAATTCATGGTGCTGGCCAACGTTGCGGCGGCGGAGACG
CTGATCGCCAAGCGAACCCCGCTGCTGTTCCGCGTCCATGAGGAGCCGTCGCCCGAGAAGCTGGAAGCCCTGCGGGAGGT
GGCCGCCAGTGCGGGTCTGACGCTCGCCAAGGGGCAGGTGTTGCAGACCCGGCACCTGAATGCGCTGCTGAAGGCGGCGG
GGGAGGATACGTCCGAGTTGATCTCCATCTCCACCCTGCGGTCGATGCAGCAGGCCTATTACAACCCCGAGAATTTCGGC
CACTTTGGGCTTGCTTTGAAAAGCTATGCCCACTTCACGTCGCCGATCCGGCGCTACGCGGATCTGATCGTGCACCGGGC
GCTGATTGCTGCCCATGGGTGGGGGCCCGACGCGAAAATAGACGGCCTGTCGCCCGATGAAATTGAACGGCTGGAAGATA
CGGCCAAGCTGATTTCGGGCACCGAACGGCGGTCCATGGTGGCGGAGCGGGACACGTCCGACCGCTATCTGGCCGCGTAT
CTCTCGGACCGGGTGGGGGCGGAATTTGGCGGGCGCATCTCGGGCATTGCGCGGTTCGGCGTGTTCGTGAAGCTGGATGA
GACGGGGGCCGATGGCCTTTTGCCGATGCGCGCTTTGGGGCAGGAATATTTCCATTTCGATGCCGAGGCGCAGACGCTGA
TGGGCGCGGATACCGGCACGATGATCAGCATCGGCGACCGGGTGCTGGTGAAGCTGGCCGAGGCCGTGCCCGTGACCGGT
GGCCTGATCCTGGAGCTTCTGGAGCATGATGGCAAAGCGCCGTCCCGTGGCTCCGGGCGCGGTGCGCGGAAGGGTGGGGG
TCGTGGGCGCGGCAAGCCGCCTGCGCGGCGCAAGGTCAGCGCCTCCAAGGCACGCAAGACGAAGCTGCGCAAAAAGCAGG
ACCGCAGCAGACCCTAG

Upstream 100 bases:

>100_bases
CTCCGGTTTGTCTCTAACGGGTGTCGCACAAGCGCTGCGGAAAATGTTTATCCTTGTTCTTTGGAGTCCGCCCTATGGAG
CATACCTGAACAATTCGTCC

Downstream 100 bases:

>100_bases
GCGATGTCCTTCAACCAGATGTTTACCACTTCCGCAGGAGGGTGACCGGCAAAAGCCCGCCCAACATTTGCGGAAATGTG
TTAGTCTTGCGCAATTCCGC

Product: ribonuclease R

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 778; Mature: 777

Protein sequence:

>778_residues
MTPPHLRATSPPMSNIPSKEQILQWITDNPGKRSKRDIAKAFGIKGAARIDLKRILRELQEEGHLEKVGRTYRDPDKLPP
VTILSVQAPDDNGDLFARPLEWHGEGVEPRVLYTPRTADPAVGQGDRILAKLFAVEGSDAEDHQYTAKLIRKIGTNPRKI
LGIFRKGAEGGVITPISKGSDKEWQVRAGDTHGAKDGELVEGELAGPKARMGAPRARITTRVGDPGAARAVSLIAIHEHG
IPDSFPNKVVAEADAAKPAGLTGREDLRDLPLITIDPADARDHDDACYAHADEDPGNKGGHVIWVAIADVAHYVTPDSAL
DREARKRGNSTYFPDRVVPMLPDRLSGDLCSLHEGVPRAVIAVRMVIDARGEKIGHTFHRGLMTSVASLSYEEAQAAQEG
TLSERTAPLIEGSIRPLFAAYDALKIARAKRQPLELDLPERRIELDDAGNVTSVAFKDRLDAHRLIEEFMVLANVAAAET
LIAKRTPLLFRVHEEPSPEKLEALREVAASAGLTLAKGQVLQTRHLNALLKAAGEDTSELISISTLRSMQQAYYNPENFG
HFGLALKSYAHFTSPIRRYADLIVHRALIAAHGWGPDAKIDGLSPDEIERLEDTAKLISGTERRSMVAERDTSDRYLAAY
LSDRVGAEFGGRISGIARFGVFVKLDETGADGLLPMRALGQEYFHFDAEAQTLMGADTGTMISIGDRVLVKLAEAVPVTG
GLILELLEHDGKAPSRGSGRGARKGGGRGRGKPPARRKVSASKARKTKLRKKQDRSRP

Sequences:

>Translated_778_residues
MTPPHLRATSPPMSNIPSKEQILQWITDNPGKRSKRDIAKAFGIKGAARIDLKRILRELQEEGHLEKVGRTYRDPDKLPP
VTILSVQAPDDNGDLFARPLEWHGEGVEPRVLYTPRTADPAVGQGDRILAKLFAVEGSDAEDHQYTAKLIRKIGTNPRKI
LGIFRKGAEGGVITPISKGSDKEWQVRAGDTHGAKDGELVEGELAGPKARMGAPRARITTRVGDPGAARAVSLIAIHEHG
IPDSFPNKVVAEADAAKPAGLTGREDLRDLPLITIDPADARDHDDACYAHADEDPGNKGGHVIWVAIADVAHYVTPDSAL
DREARKRGNSTYFPDRVVPMLPDRLSGDLCSLHEGVPRAVIAVRMVIDARGEKIGHTFHRGLMTSVASLSYEEAQAAQEG
TLSERTAPLIEGSIRPLFAAYDALKIARAKRQPLELDLPERRIELDDAGNVTSVAFKDRLDAHRLIEEFMVLANVAAAET
LIAKRTPLLFRVHEEPSPEKLEALREVAASAGLTLAKGQVLQTRHLNALLKAAGEDTSELISISTLRSMQQAYYNPENFG
HFGLALKSYAHFTSPIRRYADLIVHRALIAAHGWGPDAKIDGLSPDEIERLEDTAKLISGTERRSMVAERDTSDRYLAAY
LSDRVGAEFGGRISGIARFGVFVKLDETGADGLLPMRALGQEYFHFDAEAQTLMGADTGTMISIGDRVLVKLAEAVPVTG
GLILELLEHDGKAPSRGSGRGARKGGGRGRGKPPARRKVSASKARKTKLRKKQDRSRP
>Mature_777_residues
TPPHLRATSPPMSNIPSKEQILQWITDNPGKRSKRDIAKAFGIKGAARIDLKRILRELQEEGHLEKVGRTYRDPDKLPPV
TILSVQAPDDNGDLFARPLEWHGEGVEPRVLYTPRTADPAVGQGDRILAKLFAVEGSDAEDHQYTAKLIRKIGTNPRKIL
GIFRKGAEGGVITPISKGSDKEWQVRAGDTHGAKDGELVEGELAGPKARMGAPRARITTRVGDPGAARAVSLIAIHEHGI
PDSFPNKVVAEADAAKPAGLTGREDLRDLPLITIDPADARDHDDACYAHADEDPGNKGGHVIWVAIADVAHYVTPDSALD
REARKRGNSTYFPDRVVPMLPDRLSGDLCSLHEGVPRAVIAVRMVIDARGEKIGHTFHRGLMTSVASLSYEEAQAAQEGT
LSERTAPLIEGSIRPLFAAYDALKIARAKRQPLELDLPERRIELDDAGNVTSVAFKDRLDAHRLIEEFMVLANVAAAETL
IAKRTPLLFRVHEEPSPEKLEALREVAASAGLTLAKGQVLQTRHLNALLKAAGEDTSELISISTLRSMQQAYYNPENFGH
FGLALKSYAHFTSPIRRYADLIVHRALIAAHGWGPDAKIDGLSPDEIERLEDTAKLISGTERRSMVAERDTSDRYLAAYL
SDRVGAEFGGRISGIARFGVFVKLDETGADGLLPMRALGQEYFHFDAEAQTLMGADTGTMISIGDRVLVKLAEAVPVTGG
LILELLEHDGKAPSRGSGRGARKGGGRGRGKPPARRKVSASKARKTKLRKKQDRSRP

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014625, Length=516, Percent_Identity=28.2945736434109, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI190014623, Length=516, Percent_Identity=28.2945736434109, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI19115966, Length=502, Percent_Identity=31.2749003984064, Blast_Score=166, Evalue=1e-40,
Organism=Homo sapiens, GI219521928, Length=502, Percent_Identity=31.2749003984064, Blast_Score=166, Evalue=1e-40,
Organism=Homo sapiens, GI134288890, Length=459, Percent_Identity=30.0653594771242, Blast_Score=152, Evalue=1e-36,
Organism=Escherichia coli, GI87082383, Length=745, Percent_Identity=35.5704697986577, Blast_Score=367, Evalue=1e-102,
Organism=Escherichia coli, GI1787542, Length=491, Percent_Identity=29.1242362525458, Blast_Score=151, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI212645896, Length=484, Percent_Identity=30.1652892561983, Blast_Score=173, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI17553506, Length=382, Percent_Identity=34.8167539267016, Blast_Score=163, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6324552, Length=505, Percent_Identity=28.9108910891089, Blast_Score=169, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6320499, Length=303, Percent_Identity=26.7326732673267, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24649634, Length=386, Percent_Identity=33.160621761658, Blast_Score=177, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24654592, Length=436, Percent_Identity=28.8990825688073, Blast_Score=139, Evalue=9e-33,
Organism=Drosophila melanogaster, GI19922976, Length=436, Percent_Identity=28.8990825688073, Blast_Score=139, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24654597, Length=436, Percent_Identity=28.8990825688073, Blast_Score=139, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR013668 [H]

Pfam domain/function: PF08461 HTH_12; PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 84660; Mature: 84529

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPPHLRATSPPMSNIPSKEQILQWITDNPGKRSKRDIAKAFGIKGAARIDLKRILRELQ
CCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHH
EEGHLEKVGRTYRDPDKLPPVTILSVQAPDDNGDLFARPLEWHGEGVEPRVLYTPRTADP
HCCCHHHHHHHCCCCCCCCCEEEEEEECCCCCCCEEECCHHHCCCCCCCEEEECCCCCCC
AVGQGDRILAKLFAVEGSDAEDHQYTAKLIRKIGTNPRKILGIFRKGAEGGVITPISKGS
CCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEECCCCCCC
DKEWQVRAGDTHGAKDGELVEGELAGPKARMGAPRARITTRVGDPGAARAVSLIAIHEHG
CCCEEEEECCCCCCCCCCEEECCCCCCHHHCCCCCHHEEEECCCCCHHHHEEEEEEECCC
IPDSFPNKVVAEADAAKPAGLTGREDLRDLPLITIDPADARDHDDACYAHADEDPGNKGG
CCCCCCCCHHHCCCCCCCCCCCCHHHHHHCCEEEECCCCCCCCCCCEEEECCCCCCCCCC
HVIWVAIADVAHYVTPDSALDREARKRGNSTYFPDRVVPMLPDRLSGDLCSLHEGVPRAV
EEEEEEEHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCHHHHHCCCCHHH
IAVRMVIDARGEKIGHTFHRGLMTSVASLSYEEAQAAQEGTLSERTAPLIEGSIRPLFAA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHCCCCHHHHHH
YDALKIARAKRQPLELDLPERRIELDDAGNVTSVAFKDRLDAHRLIEEFMVLANVAAAET
HHHHHHHHHHCCCCCCCCCHHEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIAKRTPLLFRVHEEPSPEKLEALREVAASAGLTLAKGQVLQTRHLNALLKAAGEDTSEL
HHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHCCCCHHHH
ISISTLRSMQQAYYNPENFGHFGLALKSYAHFTSPIRRYADLIVHRALIAAHGWGPDAKI
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DGLSPDEIERLEDTAKLISGTERRSMVAERDTSDRYLAAYLSDRVGAEFGGRISGIARFG
CCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHCHHHCCHHHHHHHEE
VFVKLDETGADGLLPMRALGQEYFHFDAEAQTLMGADTGTMISIGDRVLVKLAEAVPVTG
EEEEECCCCCCCCCHHHHHHHHHHCCCCCHHHHCCCCCCCEEECCHHHHHHHHHHCCCCH
GLILELLEHDGKAPSRGSGRGARKGGGRGRGKPPARRKVSASKARKTKLRKKQDRSRP
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TPPHLRATSPPMSNIPSKEQILQWITDNPGKRSKRDIAKAFGIKGAARIDLKRILRELQ
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHH
EEGHLEKVGRTYRDPDKLPPVTILSVQAPDDNGDLFARPLEWHGEGVEPRVLYTPRTADP
HCCCHHHHHHHCCCCCCCCCEEEEEEECCCCCCCEEECCHHHCCCCCCCEEEECCCCCCC
AVGQGDRILAKLFAVEGSDAEDHQYTAKLIRKIGTNPRKILGIFRKGAEGGVITPISKGS
CCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEECCCCCCC
DKEWQVRAGDTHGAKDGELVEGELAGPKARMGAPRARITTRVGDPGAARAVSLIAIHEHG
CCCEEEEECCCCCCCCCCEEECCCCCCHHHCCCCCHHEEEECCCCCHHHHEEEEEEECCC
IPDSFPNKVVAEADAAKPAGLTGREDLRDLPLITIDPADARDHDDACYAHADEDPGNKGG
CCCCCCCCHHHCCCCCCCCCCCCHHHHHHCCEEEECCCCCCCCCCCEEEECCCCCCCCCC
HVIWVAIADVAHYVTPDSALDREARKRGNSTYFPDRVVPMLPDRLSGDLCSLHEGVPRAV
EEEEEEEHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCHHHHHCCCCHHH
IAVRMVIDARGEKIGHTFHRGLMTSVASLSYEEAQAAQEGTLSERTAPLIEGSIRPLFAA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHCCCCHHHHHH
YDALKIARAKRQPLELDLPERRIELDDAGNVTSVAFKDRLDAHRLIEEFMVLANVAAAET
HHHHHHHHHHCCCCCCCCCHHEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIAKRTPLLFRVHEEPSPEKLEALREVAASAGLTLAKGQVLQTRHLNALLKAAGEDTSEL
HHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHCCCCHHHH
ISISTLRSMQQAYYNPENFGHFGLALKSYAHFTSPIRRYADLIVHRALIAAHGWGPDAKI
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DGLSPDEIERLEDTAKLISGTERRSMVAERDTSDRYLAAYLSDRVGAEFGGRISGIARFG
CCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHCHHHCCHHHHHHHEE
VFVKLDETGADGLLPMRALGQEYFHFDAEAQTLMGADTGTMISIGDRVLVKLAEAVPVTG
EEEEECCCCCCCCCHHHHHHHHHHCCCCCHHHHCCCCCCCEEECCHHHHHHHHHHCCCCH
GLILELLEHDGKAPSRGSGRGARKGGGRGRGKPPARRKVSASKARKTKLRKKQDRSRP
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]