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The map label for this gene is dapD

Identifier: 89052840

GI number: 89052840

Start: 353095

End: 353922

Strand: Direct

Name: dapD

Synonym: Jann_0349

Alternate gene names: 89052840

Gene position: 353095-353922 (Clockwise)

Preceding gene: 89052837

Following gene: 89052841

Centisome position: 8.18

GC content: 63.89

Gene sequence:

>828_bases
ATGTCGAACGCTCAGCTAGAGACCGCTATCGAGGCCGCATGGGAGGCCCGTGATACGATCACCCCCGCCACCATGGGCGA
GACCCGTGAAGCGATTGAAGATACGCTGGCCGCTTTGGACGGCGGCACGCTGCGTGTGGCCGAGAAGCAGGACAGCGGCG
ACTGGCATGTGAACCAATGGGCCAAGAAGGCGGTGCTTCTGGGCTTCCGCCTGAAAGATATGGAGATGCAGGGCGGCTCC
GCGCAGGGCGGCAGCTGGTGGGACAAGGTCGACAGCAAATGGGCCACCTGGGGCGATAATGAGTGGGGCGCCGCAGGCTT
CCGTGCCGTGCCCAACTGCGTCGTGCGCAAGTCCGCCTATATCGCGCCCGGCGTGGTGCTGATGCCGTCGTTTGTGAACC
TCGGCGCCTATGTCGATAGCGGCACGATGGTCGACACCTGGGCCACCGTCGGCTCCTGCGCGCAGATCGGCAAGAACGTG
CATCTCTCGGGTGGCGTCGGCATCGGCGGCGTGTTGGAGCCGATGCAGGCCGGCCCCACGATTATTGAGGACAATTGCTT
CATCGGCGCGCGCTCGGAAGTCGTGGAAGGCTGCATCGTGCGCGAAGGCTCCGTCCTTGGCATGGGCGTCTTTATCGGCC
AGTCGACCAAGATCGTGGACCGCGAGACCGGCGATGTGATGTATGGCGAAGTGCCGTCAGGGTCCGTTGTCGTGGCGGGC
TCCCTCCCGTCCAAGAACGGCGTGAACCTTTACTGCGCGGTCATCGTGAAGCGCGTGGATGAGAGGACGCGCTCCAAAAC
CTCCATCAACGAGCTGTTGCGCGACTGA

Upstream 100 bases:

>100_bases
CCGCGATACGCGCACCAGAAACCGCGCTGCGTTGCATCACGCCGTCCCACGCACTATAGCCGCATCAAATTTGAACCGCA
CCACATCGGGAGCCGCATCC

Downstream 100 bases:

>100_bases
CCCCTCGCCCTTCCCGTCGCGCCGCCGTTTCAGCTAAGGTGGCGCTCAAACATCACTGATGAGGAGACGAGATATGCAGG
GTCTTGGATTTTTTGCGGCC

Product: 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-succinyltransferase; THDP succinyltransferase; THP succinyltransferase; Tetrahydropicolinate succinylase

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MSNAQLETAIEAAWEARDTITPATMGETREAIEDTLAALDGGTLRVAEKQDSGDWHVNQWAKKAVLLGFRLKDMEMQGGS
AQGGSWWDKVDSKWATWGDNEWGAAGFRAVPNCVVRKSAYIAPGVVLMPSFVNLGAYVDSGTMVDTWATVGSCAQIGKNV
HLSGGVGIGGVLEPMQAGPTIIEDNCFIGARSEVVEGCIVREGSVLGMGVFIGQSTKIVDRETGDVMYGEVPSGSVVVAG
SLPSKNGVNLYCAVIVKRVDERTRSKTSINELLRD

Sequences:

>Translated_275_residues
MSNAQLETAIEAAWEARDTITPATMGETREAIEDTLAALDGGTLRVAEKQDSGDWHVNQWAKKAVLLGFRLKDMEMQGGS
AQGGSWWDKVDSKWATWGDNEWGAAGFRAVPNCVVRKSAYIAPGVVLMPSFVNLGAYVDSGTMVDTWATVGSCAQIGKNV
HLSGGVGIGGVLEPMQAGPTIIEDNCFIGARSEVVEGCIVREGSVLGMGVFIGQSTKIVDRETGDVMYGEVPSGSVVVAG
SLPSKNGVNLYCAVIVKRVDERTRSKTSINELLRD
>Mature_274_residues
SNAQLETAIEAAWEARDTITPATMGETREAIEDTLAALDGGTLRVAEKQDSGDWHVNQWAKKAVLLGFRLKDMEMQGGSA
QGGSWWDKVDSKWATWGDNEWGAAGFRAVPNCVVRKSAYIAPGVVLMPSFVNLGAYVDSGTMVDTWATVGSCAQIGKNVH
LSGGVGIGGVLEPMQAGPTIIEDNCFIGARSEVVEGCIVREGSVLGMGVFIGQSTKIVDRETGDVMYGEVPSGSVVVAGS
LPSKNGVNLYCAVIVKRVDERTRSKTSINELLRD

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fourth step. [C]

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family

Homologues:

Organism=Escherichia coli, GI1786362, Length=272, Percent_Identity=64.7058823529412, Blast_Score=325, Evalue=2e-90,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): DAPD_JANSC (Q28VJ6)

Other databases:

- EMBL:   CP000264
- RefSeq:   YP_508291.1
- ProteinModelPortal:   Q28VJ6
- SMR:   Q28VJ6
- STRING:   Q28VJ6
- GeneID:   3932790
- GenomeReviews:   CP000264_GR
- KEGG:   jan:Jann_0349
- eggNOG:   COG2171
- HOGENOM:   HBG704071
- OMA:   QWAKKAV
- PhylomeDB:   Q28VJ6
- ProtClustDB:   PRK11830
- BioCyc:   JSP290400:JANN_0349-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00811
- InterPro:   IPR005664
- InterPro:   IPR018357
- InterPro:   IPR023180
- InterPro:   IPR011004
- Gene3D:   G3DSA:1.10.166.10
- TIGRFAMs:   TIGR00965

Pfam domain/function: SSF51161 Trimer_LpxA_like

EC number: =2.3.1.117

Molecular weight: Translated: 29258; Mature: 29127

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: BINDING 108-108 BINDING 145-145

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNAQLETAIEAAWEARDTITPATMGETREAIEDTLAALDGGTLRVAEKQDSGDWHVNQW
CCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHH
AKKAVLLGFRLKDMEMQGGSAQGGSWWDKVDSKWATWGDNEWGAAGFRAVPNCVVRKSAY
HHHHHHHEEEEEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCCCHHHHHCHHHHHCCCC
IAPGVVLMPSFVNLGAYVDSGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPMQAGPT
CCCCCEEHHHHHHHCEEECCCCEEEHHHHHHHHHHHCCCEEECCCCCCCHHHCHHHCCCC
IIEDNCFIGARSEVVEGCIVREGSVLGMGVFIGQSTKIVDRETGDVMYGEVPSGSVVVAG
EEECCCEECCHHHHHHHHHEECCCEEEEEEEECCCCEEEECCCCCEEEECCCCCCEEEEE
SLPSKNGVNLYCAVIVKRVDERTRSKTSINELLRD
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNAQLETAIEAAWEARDTITPATMGETREAIEDTLAALDGGTLRVAEKQDSGDWHVNQW
CCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHH
AKKAVLLGFRLKDMEMQGGSAQGGSWWDKVDSKWATWGDNEWGAAGFRAVPNCVVRKSAY
HHHHHHHEEEEEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCCCHHHHHCHHHHHCCCC
IAPGVVLMPSFVNLGAYVDSGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPMQAGPT
CCCCCEEHHHHHHHCEEECCCCEEEHHHHHHHHHHHCCCEEECCCCCCCHHHCHHHCCCC
IIEDNCFIGARSEVVEGCIVREGSVLGMGVFIGQSTKIVDRETGDVMYGEVPSGSVVVAG
EEECCCEECCHHHHHHHHHEECCCEEEEEEEECCCCEEEECCCCCEEEECCCCCCEEEEE
SLPSKNGVNLYCAVIVKRVDERTRSKTSINELLRD
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA